268 research outputs found
The metal and dust yields of the first massive stars
We quantify the role of Population (Pop) III core-collapse supernovae (SNe)
as the first cosmic dust polluters. Starting from a homogeneous set of stellar
progenitors with masses in the range [13 - 80] Msun, we find that the mass and
composition of newly formed dust depend on the mixing efficiency of the ejecta
and the degree of fallback experienced during the explosion. For standard Pop
III SNe, whose explosions are calibrated to reproduce the average elemental
abundances of Galactic halo stars with [Fe/H] < -2.5, between 0.18 and 3.1 Msun
(0.39 - 1.76 Msun) of dust can form in uniformly mixed (unmixed) ejecta, and
the dominant grain species are silicates. We also investigate dust formation in
the ejecta of faint Pop III SN, where the ejecta experience a strong fallback.
By examining a set of models, tailored to minimize the scatter with the
abundances of carbon-enhanced Galactic halo stars with [Fe/H ] < -4, we find
that amorphous carbon is the only grain species that forms, with masses in the
range 2.7 10^{-3} - 0.27 Msun (7.5 10^{-4} - 0.11 Msun) for uniformly mixed
(unmixed) ejecta models. Finally, for all the models we estimate the amount and
composition of dust that survives the passage of the reverse shock, and find
that, depending on circumstellar medium densities, between 3 and 50% (10 - 80%)
of dust produced by standard (faint) Pop III SNe can contribute to early dust
enrichment.Comment: Accepted by MNRAS, 22 pages, 12 figures, 12 table
Network-aware design-space exploration of a power-efficient embedded application
The paper presents the design and multi-parameter optimization of a networked embedded application for the health-care domain. Several hardware, software, and application parameters, such as clock frequency, sensor sampling rate, data packet rate, are tuned at design- and run-time according to application specifications and operating conditions to optimize hardware requirements, packet loss, power consumption. Experimental results show that further power efficiency can be achieved by considering also communication aspects during design space exploratio
Halo dust detection around NGC 891
Observations of edge-on galaxies allow us to investigate the vertical extent
and properties of dust, gas and stellar distributions. NGC 891 has been studied
for decades and represents one of the best studied cases of an edge-on galaxy.
We use deep PACS data together with IRAC, MIPS and SPIRE data to study the
vertical extent of dust emission around NGC 891. We also test the presence of a
more extended, thick dust component. By performing a convolution of an
intrinsic vertical profile emission with each instrument PSF and comparing it
with observations we derived the scaleheight of a thin and thick dust disc
component. For all wavelengths considered the emission is best fit with the sum
of a thin and a thick dust component. The scaleheight of both dust components
shows a gradient passing from 70 m to 250 m. This could be due to a
drop in dust heating (and thus dust temperature) with the distance from the
plane, or to a sizable contribution () of an unresolved thin
disc of hotter dust to the observed surface brightness at shorter wavelengths.
The scaleheight of the thick dust component, using observations from 70 m
to 250 m has been estimated to be kpc, consistent with
previous estimates (extinction and scattering in optical bands and MIR
emission). The amount of dust mass at distances larger than kpc from
the midplane represents % of the total galactic dust mass and the
relative abundance of small grains with respect to large grains is almost
halved comparing to that in the midplane. The paucity of small grains high
above the midplane might indicate that dust is hit by interstellar shocks or
galactic fountains and entrained together with gas. The halo dust component is
likely to be embedded in an atomic / molecular gas and heated by a thick
stellar disc.Comment: 15 pages, 13 figures, A&A accepte
Gas-to-Dust mass ratios in local galaxies over a 2 dex metallicity range
This paper analyses the behaviour of the gas-to-dust mass ratio (G/D) of
local Universe galaxies over a large metallicity range. We combine three
samples: the Dwarf Galaxy Survey, the KINGFISH survey and a subsample from
Galametz et al. (2011) totalling 126 galaxies, covering a 2 dex metallicity
range, with 30% of the sample with 12+log(O/H) < 8.0. The dust masses are
homogeneously determined with a semi-empirical dust model, including submm
constraints. The atomic and molecular gas masses are compiled from the
literature. Two XCO are used to estimate molecular gas masses: the Galactic
XCO, and a XCO depending on the metallicity (as Z^{-2}). Correlations with
morphological types, stellar masses, star formation rates and specific star
formation rates are discussed. The trend between G/D and metallicity is
empirically modelled using power-laws (slope of -1 and free) and a broken
power-law. We compare the evolution of the G/D with predictions from chemical
evolution models. We find that out of the five tested galactic parameters,
metallicity is the galactic property driving the observed G/D. The G/D versus
metallicity relation cannot be represented by a power-law with a slope of -1
over the whole metallicity range. The observed trend is steeper for
metallicities lower than ~ 8.0. A large scatter is observed in the G/D for a
given metallicity, with a dispersion of 0.37 dex in metallicity bins of ~0.1
dex. The broken power-law reproduces best the observed G/D and provides
estimates of the G/D that are accurate to a factor of 1.6. The good agreement
of the G/D and its scatter with the three tested chemical evolution models
shows that the scatter is intrinsic to galactic properties, reflecting the
different star formation histories, dust destruction efficiencies, dust grain
size distributions and chemical compositions across the sample. (abriged)Comment: 23 pages, 12 figures, accepted in Astronomy & Astrophysic
Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors.
Recent investigations have revealed that the genetic deletion of P2X7 receptors (P2rx7) results in an antidepressant phenotype in mice. However, the link between the deficiency of P2rx7 and changes in behavior has not yet been explored. In the present study, we studied the effect of genetic deletion of P2rx7 on neurochemical changes in the hippocampus that might underlie the antidepressant phenotype. P2X7 receptor deficient mice (P2rx7-/-) displayed decreased immobility in the tail suspension test (TST) and an attenuated anhedonia response in the sucrose preference test (SPT) following bacterial endotoxin (LPS) challenge. The attenuated anhedonia was reproduced through systemic treatments with P2rx7 antagonists. The activation of P2rx7 resulted in the concentration-dependent release of [3H]glutamate in P2rx7+/+ but not P2rx7-/- mice, and the NR2B subunit mRNA and protein was upregulated in the hippocampus of P2rx7-/- mice. The brain-derived neurotrophic factor (BDNF) expression was higher in saline but not LPS-treated P2rx7-/- mice; the P2rx7 antagonist Brilliant blue G elevated and the P2rx7 agonist benzoylbenzoyl ATP (BzATP) reduced BDNF level. This effect was dependent on the activation of NMDA and non-NMDA receptors but not on Group I metabotropic glutamate receptors (mGluR1,5). An increased 5-bromo-2-deoxyuridine (BrdU) incorporation was also observed in the dentate gyrus derived from P2rx7-/- mice. Basal level of 5-HT was increased, whereas the 5HIAA/5-HT ratio was lower in the hippocampus of P2rx7-/- mice, which accompanied the increased uptake of [3H]5-HT and an elevated number of [3H]citalopram binding sites. The LPS-induced elevation of 5-HT level was absent in P2rx7-/- mice. In conclusion there are several potential mechanisms for the antidepressant phenotype of P2rx7-/- mice, such as the absence of P2rx7-mediated glutamate release, elevated basal BDNF production, enhanced neurogenesis and increased 5-HT bioavailability in the hippocampus
Probing the high-redshift universe with SPICA: Toward the epoch of reionisation and beyond
With the recent discovery of a dozen dusty star-forming galaxies and around 30 quasars at z > 5 that are hyper-luminous in the infrared (μ LIR > 1013 L⊙, where μ is a lensing magnification factor), the possibility has opened up for SPICA, the proposed ESA M5 mid-/far-infrared mission, to extend its spectroscopic studies toward the epoch of reionisation and beyond. In this paper, we examine the feasibility and scientific potential of such observations with SPICA’s far-infrared spectrometer SAFARI, which will probe a spectral range (35–230 μm) that will be unexplored by ALMA and JWST. Our simulations show that SAFARI is capable of delivering good-quality spectra for hyper-luminous infrared galaxies at z = 5 − 10, allowing us to sample spectral features in the rest-frame mid-infrared and to investigate a host of key scientific issues, such as the relative importance of star formation versus AGN, the hardness of the radiation field, the level of chemical enrichment, and the properties of the molecular gas. From a broader perspective, SAFARI offers the potential to open up a new frontier in the study of the early Universe, providing access to uniquely powerful spectral features for probing first-generation objects, such as the key cooling lines of low-metallicity or metal-free forming galaxies (fine-structure and H2 lines) and emission features of solid compounds freshly synthesised by Population III supernovae. Ultimately, SAFARI’s ability to explore the high-redshift Universe will be determined by the availability of sufficiently bright targets (whether intrinsically luminous or gravitationally lensed). With its launch expected around 2030, SPICA is ideally positioned to take full advantage of upcoming wide-field surveys such as LSST, SKA, Euclid, and WFIRST, which are likely to provide extraordinary targets for SAFARI
Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects
In a large multicentre study, Toledo et al. examine core Alzheimer's disease CSF biomarkers in 1233 cognitively normal subjects aged 40-85 years. Alzheimer disease-like changes in Aβ1-42 are seen as early as middle age, while APOE genotype strongly modifies age-related effects on both Aβ1-42 and phosphorylated/total ta
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