Safety of hospital discharge before return of bowel function after elective colorectal surgery

Background Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien-Dindo classification system. Results A total of 3288 patients were included in the analysis, of whom 301 (9 center dot 2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4-7) and 7 (6-8) days respectively (P < 0 center dot 001). There were no significant differences in rates of readmission between these groups (6 center dot 6 versus 8 center dot 0 per cent; P = 0 center dot 499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0 center dot 90, 95 per cent c.i. 0 center dot 55 to 1 center dot 46; P = 0 center dot 659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34 center dot 7 versus 39 center dot 5 per cent; major 3 center dot 3 versus 3 center dot 4 per cent; P = 0 center dot 110). Conclusion Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients

Search for a light charged Higgs boson decaying to c-sbar in pp collisions at sqrt(s) = 8 TeV

see paper for full list of authorsInternational audienceA search for a light charged Higgs boson, originating from the decay of a top quark and subsequently decaying into a charm quark and a strange antiquark, is presented. The data used in the analysis correspond to an integrated luminosity of 19.7 inverse-femtobarns recorded in proton-proton collisions at sqrt(s) = 8 TeV by the CMS experiment at the LHC. The search is performed in the process t tbar to W+/- b H-/+ bbar, where the W boson decays to a lepton (electron or muon) and a neutrino. The decays lead to a final state comprising an isolated lepton, at least four jets and large missing transverse energy. No significant deviation is observed in the data with respect to the standard model predictions, and model-independent upper limits are set on the branching fraction BF( t to H+ b ), ranging from 1.2 to 6.5% for a charged Higgs boson with mass between 90 and 160 GeV, under the assumption that BF( H+ to c sbar ) = 100%

Measurement of charged pion, kaon, and proton production in proton-proton collisions at root s=13 TeV

Transverse momentum spectra of charged pions, kaons, and protons are measured in proton-proton collisions at √s = 13 TeV with the CMS detector at the LHC. The particles, identified via their energy loss in the silicon tracker, are measured in the transverse momentum range of pT ∼ 0.1-1.7 GeV/c and rapidities /y/ < 1. The pT spectra and integrated yields are compared to previous results at smaller √s and to predictions of Monte Carlo event generators. The average pT increases with particle mass and charged particle multiplicity of the event. Comparisons with previous CMS results at √s = 0.9, 2.76, and 7 TeV show that the average pT and the ratios of hadron yields feature very similar dependences on the particle multiplicity in the event, independently of the center-of-mass energy of the pp collision