Helium Emission in the Type Ic SN 1999cq

We present the first unambiguous detection of helium emission lines in spectra of Type Ic supernovae (SNe Ic). The presence of He I lines, with full width at half maximum ~ 2000 km/s, and the distinct absence of any other intermediate-width emission (e.g., Halpha), implies that the ejecta of SN Ic 1999cq are interacting with dense circumstellar material composed of almost pure helium. This strengthens the argument that the progenitors of SNe Ic are core-collapse events in stars that have lost both their hydrogen and helium envelopes, either through a dense wind or mass-transfer to a companion. In this way, SN 1999cq is similar to supernovae such as SN 1987K and SN 1993J that helped firmly establish a physical connection between Type Ib and Type II supernovae. The light curve of SN 1999cq is very fast, with an extremely rapid rise followed by a quick decline. SN 1999cq is also found to exhibit a high level of emission at blue wavelengths (< 5500 A), likely resulting from either an unusually large amount of iron and iron-group element emission or uncharacteristically low reddening compared with other SNe Ic.Comment: 17 pages (AASTeX V5.0), 4 figures, accepted for publication in the Astronomical Journa

The Construction and Validation of an Abridged Version of the Autism-Spectrum Quotient (AQ-Short)

This study reports on the development and validation of an abridged version of the 50-item Autism-Spectrum Quotient (AQ), a self-report measure of autistic traits. We aimed to reduce the number of items whilst retaining high validity and a meaningful factor structure. The item reduction procedure was performed on data from 1,263 Dutch students and general population adults. The resulting 28-item AQ-Short was subsequently validated in 3 independent samples, both clinical and controls, from the Netherlands and the UK. The AQ-Short comprises two higher-order factors assessing ‘social behavioral difficulties’ and ‘a fascination for numbers/patterns’. The clear factor structure of the AQ-Short and its high sensitivity and specificity make the AQ-Short a useful alternative to the full 50-item version

Radio emission of SN1993J: the complete picture. I. Re-analysis of all the available VLBI data

We have performed a complete re-calibration and re-analysis of all the available VLBI observations of supernova SN1993J, following an homogeneous and well-defined methodology. Observations of SN1993J at 69 epochs, spanning 13 years, were performed by two teams, which used different strategies and analysis tools. The results obtained by each group are similar, but their conclusions on the supernova expansion and the shape and evolution of the emitting region differ significantly. From our analysis of the combined set of observations, we have obtained an expansion curve with unprecedented time resolution and coverage. We find that the data from both teams are compatible when analyzed with the same methodology. One expansion index ($m_3 = 0.87 \pm 0.02$) is enough to model the expansion observed at 1.7\,GHz, while two expansion indices ($m_1 = 0.933\pm0.010$ and $m_2 = 0.796\pm0.005$), separated by a break time, $t_{br} = 390\pm30$ days, are needed to model the data, at frequencies higher than 1.7\,GHz, up to day 4000 after explosion. We thus confirm the wavelength dependence of the size of the emitting region reported by one of the groups. We also find that all sizes measured at epochs later than day 4000 after explosion are systematically smaller than our model predictions. We estimate the fractional shell width ($0.31 \pm 0.02$, average of all epochs and frequencies) and the level of opacity to the radio emission by the ejecta. We find evidence of a spectral-index radial gradient in the supernova shell, which is indicative of a frequency-dependent ejecta opacity. Finally, we study the distribution and evolution of the azimuthal anisotropies (hot spots) found around the radio shell during the expansion. These anisotropies have intensities of $\sim 20$% of the mean flux density of the shell, and appear to systematically evolve during the expansion.Comment: 13 pages, 9 figures, accepted for publication in A&

‘They’re more like ordinary stroppy British women’: Attitudes and expectations of maternity care professionals to UK-born ethnic minority women

Objective To explore the attitudes and expectations of maternity care professionals to UK-born ethnic minority mothers. Methods Qualitative in-depth interviews with 30 professionals from eight NHS maternity units in England that provide services for large proportions of women of black Caribbean, black African, Indian, Pakistani and Irish descent. Results All the professionals reported providing care to both UK-born and migrant mothers from ethnic minorities. Most of them felt that they could differentiate between UK-born and migrant mothers based mainly on language fluency and accent. ‘Westernized dress’ and ‘freedom’ were also cited as indicators. Overall, professionals found it easier to provide services to UK-born mothers and felt that their needs were more like those of white English mothers than those of migrant mothers. UK-born mothers were generally thought to be assertive and expressive, and in control of care-related decision-making whereas some South Asian Muslim women were thought to be constrained by family influences. Preconceived ideas about ethnic minority mothers' tolerance of pain in labour, use of pharmacological pain relief measures and mode of delivery were recurring themes. Women's education and social class were felt to be major influences on the uptake of maternity care, regardless of ethnicity. Conclusions Professionals appeared to equate the needs of UK-born ethnic minority women with those of white English women. Overall, this has positive implications for care provision. Despite this, specific behavioural expectations and unconscious stereotypical views were evident and have the potential to affect clinical practice

A Decade of SN1993J: Discovery of Wavelength Effects in the Expansion Rate

We have studied the growth of the shell-like radio structure of supernova SN1993J in M81 from September 1993 through October 2003 with very-long-baseline interferometry (VLBI) observations at the wavelengths of 3.6, 6, and 18cm. For this purpose, we have developed a method to accurately determine the outer radius (R) of any circularly symmetric compact radio structure like SN1993J. The source structure of SN1993J remains circularly symmetric (with deviations from circularity under 2%) over almost 4000 days. We characterize the decelerated expansion of SN 1993J through approximately day 1500 after explosion with an expansion parameter $m= 0.845\pm0.005$ ($R \propto t^{m}$). However, from that day onwards the expansion is different when observed at 6 and 18cm. Indeed, at 18cm, the expansion can be well characterized by the same $m$ as before day 1500, while at 6cm the expansion appears more decelerated, and is characterized by another expansion parameter, $m_{6}= 0.788\pm0.015$. Therefore, since about day 1500 on, the radio source size has been progressively smaller at 6cm than at 18cm. These findings are in stark contrast to previous reports by other authors on the details of the expansion. In our interpretation the supernova expands with a single expansion parameter, $m= 0.845\pm0.005$, and the 6cm results beyond day 1500 are due to physical effects, perhaps also coupled to instrumental limitations. Two physical effects may be involved: (a) a changing opacity of the ejecta to the 6cm radiation, and (b) a radial decrease of the magnetic field in the emitting region. (Long abstract cut. Please, read full abstract in manuscript).Comment: 21 pages, 19 figures, accepted in A&

Absolute Single-Molecule Entropies from Quasi-Harmonic Analysis of Microsecond Molecular Dynamics: Correction Terms and Convergence Properties

The convergence properties of the absolute single-molecule configurational entropy and the correction terms used to estimate it are investigated using microsecond molecular dynamics simulation of a peptide test system and an improved methodology. The results are compared with previous applications for systems of diverse chemical nature. It is shown that (i) the effect of anharmonicity is small, (ii) the effect of pairwise correlation is typically large, and (iii) the latter affects to a larger extent the entropy estimate of thermodynamic states characterized by a higher motional correlation. The causes of such deviations from a quasi-harmonic behavior are explained. This improved approach provides entropies also for molecular systems undergoing conformational transitions and characterized by highly frustrated energy surfaces, thus not limited to systems sampling a single quasi-harmonic basin. Overall, this study emphasizes the need for extensive phase-space sampling in order to obtain a reliable estimation of entropic contributions

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in neuroscience, psychiatry, neurology, and genetics. Most ENIGMA WGs focus on specific psychiatric and neurological conditions, other WGs study normal variation due to sex and gender differences, or development and aging; still other WGs develop methodological pipelines and tools to facilitate harmonized analyses of "big data" (i.e., genetic and epigenetic data, multimodal MRI, and electroencephalography data). These international efforts have yielded the largest neuroimaging studies to date in schizophrenia, bipolar disorder, major depressive disorder, post-traumatic stress disorder, substance use disorders, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, autism spectrum disorders, epilepsy, and 22q11.2 deletion syndrome. More recent ENIGMA WGs have formed to study anxiety disorders, suicidal thoughts and behavior, sleep and insomnia, eating disorders, irritability, brain injury, antisocial personality and conduct disorder, and dissociative identity disorder. Here, we summarize the first decade of ENIGMA's activities and ongoing projects, and describe the successes and challenges encountered along the way. We highlight the advantages of collaborative large-scale coordinated data analyses for testing reproducibility and robustness of findings, offering the opportunity to identify brain systems involved in clinical syndromes across diverse samples and associated genetic, environmental, demographic, cognitive, and psychosocial factors

Event Monitoring System to Classify Unexpected Events for Production Planning

[EN] Production planning prepares companies to a future production scenario. The decision process followed to obtain the production plan considers real data and estimated data of this future scenario. However, these plans can be affected by unexpected events that alter the planned scenario and in consequence, the production planning. This is especially critical when the production planning is ongoing. Thus providing information about these events can be critical to reconsider the production planning. We herein propose an event monitoring system to identify events and to classify them into different impact levels. The information obtained from this system helps to build a risk matrix, which determines the significance of the risk from the impact level and the likelihood. 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