Projeto de lareira à lenha com sistema de circulação de ar forçado

A energia é a capacidade de produzir um trabalho ou realizar uma ação. Ela é associada a, entre outros, energia elétrica, calor e movimento de um ou mais corpos. A eletricidade, por exemplo, pode ser produzida por fontes não renováveis: derivados de petróleo, carvão mineral e gás natural. Este processo traz muitos problemas ao ecossistema global, como a exaustão dos recursos naturais, efeito estufa e as mudanças climáticas. Também pode ser obtida por fontes renováveis, como a biomassa, solar e eólica; estas geram menos poluentes ou riscos e tendem a ser repostas com maior facilidade na natureza. O objetivo deste trabalho foi desenvolver uma lareira para aquecimento residencial que utiliza a lenha para a combustão, visando a redução no consumo de energia elétrica e preservação do meio ambiente. Além disso, aplicando os métodos e processos corretos de produção visa-se oferecer menos impacto ao ecossistema. Melhores resultados para o fornecimento de caloria são atingidos através de um sistema que emprega os fumos da queima para movimentar ventiladores que deslocam o ar quente para o ambiente, trazendo mais conforto e bem estar ao usuário.Energy is the ability of producing work or performing an action. It can be associated to, among others, electrical energy, heat and movement of one or more bodies. Electricity, for instance, can be produced by non-renewable fonts: petroleum products, coal and natural gas. This process brings a lot of problems to the global ecosystem, such as the exhaustion of natural resources, greenhouse effect and climate change. It can also be obtained from renewable sources, such as biomass, solar and wind; these generate fewer pollutants or risks and tend to be replenished more easily in nature. The goal of this work is to develop a fireplace for residential heating that uses firewood for combustion, aiming at a reduction to the use of electrical energy and environmental preservation. Besides, by applying the correct methods and processes in production the impact to the ecosystem is also reduced. Better results to the heat delivery are reached using a system that uses the burning fumes to move fans that move the hot air to the environment, bringing the user more comfort and well-being

Incidence of tuberculosis infection in spondyloarthritis patients treated with biological and conventional diseasemodifying anti-rheumatic drugs in an endemic area

Introduction: Registries of spondyloarthritis (SpA) patients’ follow-up provided evidence that tumor necrosis factor inhibitors (TNFi) increase the incidence of active tuberculosis infection (TB). However, most of these registries are from low burden TB areas. Few studies evaluated the safety of biologic agents in TB endemic areas. This study compares the TB incidence rate (TB IR) in anti-TNF-naïve and anti-TNFexperienced subjects with SpA in a high TB incidence setting. Methods: In this retrospective cohort study, medical records from patients attending a SpA clinic during 13 years (2004 to 2016) in a university hospital were reviewed. The TB IR was calculated and expressed as number of events per 105 patients/year; the incidence rate ratio (IRR) associated with the use of TNFi was calculated. Results: A total of 277 patients, 173 anti-TNF-naïve and 104 anti-TNF-experienced subjects, were evaluated; 35.7% (N = 35) of patients who were prescribed an antiTNF drug were diagnosed with latent tuberculosis infection (LTBI). Total follow-up time (person-years) was 1667.8 for anti-TNF-naïve and 394.9 for anti-TNF-experienced patients. TB IR (95% CI) was 299.8 (37.4-562.2) for anti-TNF naïve and 1012.9 (25.3-2000.5) for anti-TNF experienced subjects. The IRR associated with the use of TNFi was 10.4 (2.3- 47.9). Conclusions: In this high TB incidence setting, SpA patients exposed to anti-TNF therapy had a higher incidence of TB compared to anti-TNF-naïve subjects, although the TB incidence in the control group was significant

The STAR-RICH Detector

The STAR-RICH detector extends the particle idenfication capabilities of the STAR spectrometer for charged hadrons at mid-rapidity. It allows identification of pions and kaons up to ~3 GeV/c and protons up to ~5 GeV/c. The characteristics and performance of the device in the inaugural RHIC run are described

Centrality evolution of the charged-particle pseudorapidity density over a broad pseudorapidity range in Pb-Pb collisions at root s(NN)=2.76TeV

Peer reviewe

Geometrically nonlinear static and dynamic analysis of composite laminates shells with a triangular finite element

Geometrically nonlinear static and dynamic behaviour of laminate composite shells are analyzed in this work using the Finite Element Method (FEM). Triangular elements with three nodes and six degrees of freedom per node (three displacement and three rotation components) are used. For static analysis the nonlinear equilibrium equations are solved using the Generalized Displacement Control Method (GDCM) while the dynamic solution is performed using the classical Newmark Method with an Updated Lagrangean Formulation (ULF). The system of equations is solved using the Gradient Cojugate Method (GCM) and in nonlinear cases with finite rotations and displacements an iterativeincremental scheme is employed. Numerical examples are presented and compared with results obtained by other authors with different kind of elements and different schemes

Linear static and dynamic analysis of thin laminated composite structures with a triangular finite element

Linear static and dynamic behavior of thin laminate composite structures are analyzed in this study using the Finite Element Method (FEM). Triangular elements with three nodes and six degrees of freedom per node (three displacement and three rotation components) are used. For static analysis the equilibrium equations are solved using Pre-conditioned Gradient Conjugate Method (GCM) while the dynamic solution is performed using the classical Newmark Method. Analytical evaluation of consistent element mass matrix and determination of membrane and membrane-bending coupling element stiffness matrix in the explicit form are showed. Numerical examples are presented and compared with results obtained by other authors with different types of elements and different schemes, proving the validity and effectiveness of the developed model

Extrato da casca de Syzygium cumini no controle da glicemia e estresse oxidativo de ratos normais e diabéticos

O Syzygium cumini, também conhecido como Jambolão é amplamente utilizado na medicina popular para o tratamento da diabetes melito. Este estudo verificou a eficiência do extrato da casca de Syzygium cumini sobre os níveis glicêmicos e estresse oxidativo de ratos normais e diabéticos induzidos por aloxano. Os animais foram divididos em grupo controle (C), controle tratado (CT), diabético controle (DC) e diabético tratado (DT). A administração oral do extrato aquoso da casca de Jambolão, na dose de 1g/kg de peso vivo, por um período de trinta dias, não resultou em uma redução significativa na glicemia e nos níveis de hemoglobina glicosilada. Neste estudo, o tratamento com o extrato demonstrou um aumento dos níveis de substâncias reativas ao ácido tiobarbitúrico (TBA-RS) no plasma dos ratos do grupo DT (P<0,05), comparado com o C. A atividade da catalase nos rins dos ratos do grupo DC diminuiu significativamente (P<0,01) e no fígado houve uma elevação significativa dessa enzima no grupo DC (P<0,01). Estes resultados indicam que o extrato da casca do Jambolão não possui efeito hipoglicemiante em ratos diabéticos induzidos pelo aloxano. O efeito antioxidante desta planta não foi suficiente para diminuir significativamente a produção de TBA-RS. A diminuição da atividade da catalase nos rins pode ser devida à exaustão ou inibição desta enzima e seu aumento, no fígado, devido ao estresse oxidativo, ocasionado pelo estado diabético

In vitro effects of L-arginine and guanidino compounds on NTPDase1 and 5'-nucleotidase activities from rat brain synaptosomes

Tissue accumulation of arginine (Arg), N-acetylarginine (NA), argininic acid (AA) and homoarginine (HA) occurs in hyperargininemia, an inborn error of the urea cycle. In the present study, we investigated the in vitro effects of Arg, NA, AA and HA on NTPDase1 and 5′-nucleotidase activities from synaptosomal cerebral cortex of rats. The results showed that Arg enhances NTPDase1 activity at the high concentrations tested (1.5 and 3.0 mM) for both the ATP and ADP nucleotides. Activation was also observed with other guanidino compounds tested: NA, AA and HA activated ATP and ADP hydrolysis in all experiments at the concentration of 25 μM. Besides this, NA and AA activated ATP hydrolysis at a lower concentration (1 μM). In another set of experiments, we verified the effect of Arg on purified apyrase at pH 8.0 and 6.5 and observed an increase in the enzyme activity at all Arg concentrations tested (0.01–3.0 mM). In contrast, Arg and the other guanidino compounds tested did not alter 5′-nucleotidase activity. These results suggest that changes in nucleotide hydrolysis may be involved in the brain dysfunction caused by hyperargininemia amongst other potential pathophysiological mechanisms involved in this condition