Post-Hospital Syndrome and Hyponatremia

Introduction: Post-hospital syndrome (PHS) is defined as a period of vulnerability during the first 30 days after a patient is discharged from hospital, in which multiple factors come into play. Hyponatremia is the most frequent hydroelectrolytic disorder in hospitalized patients and may be related to the appearance of PHS. Objective: The objective is to estimate the prevalence of PHS that is assessed as the rate of readmissions in the first 30 days after discharge, in patients with hyponatremia. Material and Methods: It is a descriptive observational study of patients with hyponatremia who were discharged from 1 September 2010 to 2 February 2020 at the Internal Medicine Service of the Hospital University of San Juan (Alicante, Spain). Results: Of the 25 included patients, 5 (20%) were readmitted within a month of discharge, after a mean of 11.4 days (standard deviation [SD] 5.1). The overall mortality of the study was 20% (n = 5), with one case of death in the first 30 days post-hospitalization (4%). In 12 patients (48%) the origin of the hyponatremia was undetermined. The most frequently recorded etiology for the condition was pharmacological (n = 7, 28%), and there was pronounced variability in its clinical and laboratory study. The most widely used corrective measure was drug withdrawal, in 16 patients (64%). Water intake restriction was the most common treatment after discharge (5 patients, 20%), followed by urea (2 patients, 8%), while tolvaptan was not used. Conclusion: Hyponatremia may be the cause of PHS, which could increase the rate of early readmission. Hyponatremia is an underdiagnosed and undertreated entity, so it is necessary to apply an appropriate system to optimize its management and, in future studies, to assess its impact on PHS

An assessment of the cost-effectiveness of magnetic resonance, including diffusion-weighted imaging in patients with transient ischaemic attack and minor stroke : a systematic review, meta-analysis and economic evaluation

Erratum issued September 2015 Erratum DOI: 10.3310/hta18270-c201509Peer reviewedPublisher PD

MRI Diagnosis of Intracranial Hemorrhage: Experimental and Clinical Studies

The purpose of this work was to improve the diagnosis of intracranial hemorrhage with MRI, using, among others, T2*-w GE sequences. Various sequences were tested in rabbits at two magnetic field strengths. Then, the most effective technique was applied to stroke patients. Experimental studies: The MR detectability of small experimental haematomas in the brain and of blood in the cerebrospinal fluid (CSF) spaces of 30 rabbits was evaluated. MRI examinations were performed at determined intervals. The last MR images were compared to formalin fixed brain sections and, in 16 rabbits, also to the histological findings. T2*-weighted GE sequences revealed all the intraparenchymal haematomas at 1.5 T, appearing strongly hypointense. Their signal patterns remained unchanged during the follow-up. Blood in the CSF spaces was best detected at 1.5T with T2*-weighted GE sequences during the first 2 days. FLAIR and SE sequences were rather insensitive. Clinical studies: MR examinations were performed at 1.5T, including T1- and T2-w SE, FLAIR and T2*-w GE sequences. In the first clinical study, 66 intraparenchymal hematomas (IPH) of different sizes and ages were examined. T2*-w GE sequence was the most sensitive. On all the sequences, we found a big variety of signal patterns, without a clear relationship to the age of the hematomas. In a second clinical study, MR examinations were performed to 83 patients with acute stroke: 43 presented acute IPH and 40 were used as controls. Old microhemorrhages (OMHs) were found in 60% of the patients with IPH, and in 15% of the controls. Conclusion: T2*-weighted GE sequences are capable of revealing very small intraparenchymal hemorrhages at any stage, and blood in CSF spaces during at least the first 2 days. The age of IPHs cannot reliably be estimated with MRI. We have found a correlation between the presence of OMHs and acute intraparenchymal hematomas

Mapping between Industry 5.0 and Education 5.0

[EN] This paper performs a mapping between Industry 5.0 and Education 5.0. and identifies how the concepts of Industry 5.0 can be applied in education. Industry 4.0, has sought to minimize human intervention and prioritize the automation of processes. To some extent, the human being has been made to compete with machines, displacing the former from a multitude of scenarios. In the case of Industry 5.0, this trend is reversed: it is about generating a balance in which machine-human interaction is capable of providing maximum benefits. The current paper considers the following perspectives of Industry 5.0: cost optimization, sustainability, personalization and creativity, and resilience for its mapping towards Education 5.0 in industrial engineering courses.The authors acknowledge the support from the Universitat Politècnica de València (UPV) through the Projects of Innovation and Educational Improvement "La docencia inversa como metodología soporte a metodologías activas de aprendizaje" (PIME/21-22/263) and "Innovación y mejora educativa aplicada a los Objetivos de Desarrollo Sostenible en la ETSII" (PIME/21-22/281).Andres, B.; Sempere-Ripoll, F.; Esteso, A.; Alemany Díaz, MDM. (2022). Mapping between Industry 5.0 and Education 5.0. EDULEARN Proceedings (Internet). 2921-2926. https://doi.org/10.21125/edulearn.2022.07392921292

IBV realiza el estudio antropométrico de la población femenina en España promovido por el INC

Last month of February, the Minister of Health and Consumption, Mr. Bernat Soria, presented the results of the anthropometric study of the Spanish feminine population in Spain. This study was carried out by the Institute of Biomechanics of Valencia, which was the successful bidder of the contest summoned by the National Institute of Consumption (INC) for the accomplishment of a study in which has been registered the anthropometrical dimensions of 10.415 women between 12 and 70 years old. These results constitute the starting point to elaborate a new sizing system for the textile and confection sector in the frame of the agreement signed in 2007 by the Ministry of Health and Consumption with the associations and companies of the sectors of confection, distribution, fashionable design and knitted garment in Spain. The objective is to define the shape and dimensions of the body of the Spanish woman and, starting from the standard IN 13402-3-2004, to develop a system of homogeneous pattern design, adapted to the users, which there could use all the designers, manufacturers and distributors.EL PASADO MES DE FEBRERO EL MINISTRO DE SANIDAD Y CONSUMO, D. BERNAT SORIA, PRESENTÓ LOS RESULTADOS DEL estudio antropométrico de la población femenina en España realizado por el Instituto de Biomecánica deValencia, que fue el adjudicatario del concurso convocado por el Instituto Nacional de Consumo (INC) para la realización de un estudio en el que se han registrado las dimensiones antropométricas de 10.415 mujeres de entre 12 y 70 años. Estos resultados constituyen el punto de partida para elaborar un nuevo sistema de tallaje para el sector textil y de la confección en el marco del acuerdo suscrito en 2007 por el Ministerio de Sanidad y Consumo con las asociaciones y empresas de los sectores de confección, distribución, diseño de moda y género de punto en España. El objetivo es definir la forma y dimensiones del cuerpo de la mujer española y, partiendo de la norma EN 13402-3-2004, desarrollar un sistema de patronaje homogéneo, adaptado a las usuarias, que puedan utilizar todos los diseñadores, fabricantes y distribuidores

Validation of F-18-FDG PET/MRI and diffusion-weighted MRI for estimating the extent of peritoneal carcinomatosis in ovarian and endometrial cancer : a pilot study

Background: The extent of peritoneal carcinomatosis is difficult to estimate preoperatively, but a valid measure would be important in identifying operable patients. The present study set out to validate the usefulness of integrated F-18-FDG PET/MRI, in comparison with diffusion-weighted MRI (DW-MRI), for estimation of the extent of peritoneal carcinomatosis in patients with gynaecological cancer. Methods: Whole-body PET/MRI was performed on 34 patients with presumed carcinomatosis of gynaecological origin, all scheduled for surgery. Two radiologists evaluated the peritoneal cancer index (PCI) on PET/MRI and DW-MRI scans in consensus. The surgeon estimated PCI intraoperatively, which was used as the gold standard. Results: Median total PCI for PET/MRI (21.5) was closer to surgical PCI (24.5) (p = 0.6), than DW-MRI (median PCI 20.0, p = 0.007). However, both methods were highly correlated with the surgical PCI (PET/MRI: beta = 0.94 p < 0.01, DW-MRI: beta = 0.86, p < 0.01). PET/MRI was more accurate (p = 0.3) than DW-MRI (p = 0.001) when evaluating patients at primary diagnosis but no difference was noted in patients treated with chemotherapy. PET/MRI was superior in evaluating high tumour burden in inoperable patients. In the small bowel regions, there was a tendency of higher sensitivity but lower specificity in PET/MRI compared to DW-MRI. Conclusions: Our results suggest that FDG PET/MRI is superior to DW-MRI in estimating total spread of carcinomatosis in gynaecological cancer. Further, the greatest advantage of PET/MRI seems to be in patients at primary diagnosis and with high tumour burden, which suggest that it could be a useful tool when deciding about operability in gynaecological cancer