88 research outputs found

    Hysteretic response characteristics and dynamic phase transition via site dilution in the kinetic Ising model

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    The decay of the hysteresis loop area of the system, which is obeying a site diluted kinetic Ising model, is considered by the disorder parameter using the effective field theory analysis. The exhibition focuses on the understanding of external field frequency, amplitude and the site concentration dependency of the hysteresis loop area for several powerful treatments. Important characteristics of the hysteretic response, such as frequency dispersion, effect of domain nucleation phenomenon on the dynamic process etc. has been introduced together with well known other characteristics. An attempt has been made to explain the relations between the competing time scales (intrinsic microscopic relaxation time of the system and the time period of the external oscillatory field) and the shape of the response. As a result of the detailed investigations, existence of essentially three, particularly four types of dispersion curves have been propounded.Comment: 16 pages, 8 figure

    Turner syndrome and associated problems in turkish children: A multicenter study

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    Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosi) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto’s thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. © Journal of Clinical Research in Pediatric Endocrinology

    Sleep problems during COVID-19 pandemic and its’ association to psychological distress: a systematic review and meta-analysis

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    Background: The emerging novel coronavirus disease 2019 (COVID-19) has become one of the leading cause of deaths worldwide in 2020. The present systematic review and meta-analysis estimated the magnitude of sleep problems during the COVID-19 pandemic and its relationship with psychological distress. Methods: Five academic databases (Scopus, PubMed Central, ProQuest, ISI Web of Knowledge, and Embase) were searched. Observational studies including case-control studies and cross-sectional studies were included if relevant data relationships were reported (i.e., sleep assessed utilizing the Pittsburgh Sleep Quality Index or Insomnia Severity Index). All the studies were English, peer-reviewed papers published between December 2019 and February 2021. PROSPERO registration number: CRD42020181644. Findings: 168 cross-sectional, four case-control, and five longitudinal design papers comprising 345,270 participants from 39 countries were identified. The corrected pooled estimated prevalence of sleep problems were 31% among healthcare professionals, 18% among the general population, and 57% among COVID-19 patients (all p-values < 0.05). Sleep problems were associated with depression among healthcare professionals, the general population, and COVID-19 patients, with Fisher's Z scores of -0.28, -0.30, and -0.36, respectively. Sleep problems were positively (and moderately) associated with anxiety among healthcare professionals, the general population, and COVID-19 patients, with Fisher's z scores of 0.55, 0.48, and 0.49, respectively. Interpretation: Sleep problems appear to have been common during the ongoing COVID-19 pandemic. Moreover, sleep problems were found to be associated with higher levels of psychological distress. With the use of effective programs treating sleep problems, psychological distress may be reduced. Vice versa, the use of effective programs treating psychological distress, sleep problems may be reduced

    Yapı Değişikliklerinin Yönetimi ve Yapı Bilgi Modellerinin Bir Parçası Olarak Kayda Geçirilmesi

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    Yapı lar tasarımdan yıkıma kadar tü m yaşam sü releri boyunca birçok değişikliğe uğrar. Bu değişiklikl er in tasarım ve imalat aşaması nda gerçekleşenleri planlar üzerinde saklanmaya çalışılsa da özellikle tesis yönetimi sürecinde meydana gelen bakım, onarı m ve tadilat değiş iklikleri nin bir çoğu formel bir ş ekilde saklanmaz. Yapımdan sonra meydana gelen bu tü r değişikliklerin saklanmaması ve bir değ işiklik geçmiş inin bulunmayışı, binaların en uzun evresi olan tesis y ö netimi s ü resinc e, gü ncellenmemi ş ve g ü venilemez plan ve bina bilgilerine dayanı larak i ş letilmesi ve yö netilmesine neden olmaktadı r. De ğ i ş iklikler d üzenli olarak kayda ge ç irilmedi ğinde, bina kayı tlar ının g ü ncellenmesi yüksek maliyetlere sebep olmakta, ancak g ü ncellenmemeleri daha da ciddi sorunlara yol a çabilmekte dir. Ö rneğin bakım/onarım personelinin iş s ü re ç leri gerekli ve gü ncel bina bilgiler in e ula şılamadığı için uzamakta , ayrıca afet ve acil durum sırasında yapı la ra mü daha le edilirken bina kayı tlar ında olmayan beklenmedik durumlarla kar şı la şılmaktad ır. Bu bildiride, bahsedilen olumsuzlukları ö nleme ye yardı mc ı olmak amac ıyla geli ş tirilen formel bir yakla şı mda, bina değ i ş ikliklerini dü ze nleme ve değ i şiklik ge ç mi şini kaydetme yö nteminin genel bir tan ımı ve anlat ımı yapı lmaktad ı r. Geli ş tirilen yakla şım tesis y ö netimi esnas ında en sık ger ç ekleşen bakı m/ onarım sonucundaki değ i ş iklik l erin kaydedilmesini ve Yap ı Bilgi Modellerinin ( YBM, Buildin g Information Models - BIM ) bir par ç as ı olarak saklanmas ını iç erir. Bu yakla şı mla YBM ’ nin bir par ç as ı olarak saklanan değ i şiklikler, daha sonra bina kayı tlar ının (yani modellerin) g ü ncellenme gere ğinin anla şı lmas ı , nerelerin g ü ncellenmesine ö ncelik verilme si gerekti ğ i nin belirlenmesi ve binada s ıklıkl a olu şan problemlerin idraki ile yeni bakım ve onarım planlarının yapı lmas ı için destek sa ğ lamay ı öngö rmektedi
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