74 research outputs found
Varicocele Surgery Improves Sperm Count in Infertile Oligospermic Patients and so Improves Fertility; A Study in a Tertiary Care Hospital
- Publication venue
- Faculty of Medicine, UKM Medical Centre
- Publication date
- 14/12/2015
- Field of study
The objective of this study was to find out the role of varicocele surgery in oligospermic infertile patients. It was a prospective and descriptive study carried out in Surgical Unit-I, Abbasi Shaheed Hospital and Karachi Medical and Dental College (KMDC), Karachi from April 2004 to March 2014. In this study, all patients of infertility due to low sperm count having bilateral varicocele were included while those patients having azoospermia or patients with unilateral varicocele were excluded. All patients were clinically assessed for bilateral varicocele and confirmed by ultrasonography of scrotum and relevant investigations were done. Patients were prepared for varicocele surgery and ligation of pampiniform plexus done. Semenanalysis were done during follow up and results were analyzed on SPSS version 14. Total fifty seven patients (n=57) were included in which age range was 20 to 30 years in 33.3%, 31 to 40 years in 42.1%, 41 to 50 years in 19.3% and 51 years to onwards in 05.3% patients only. Chronic smoking was found in 68.4% patients while 31.6% were nonsmokers. Normal testes was found in 77.19% while 22.81% had smaller (atrophied) testes. Very low sperm count was in 15.79%, 50.88% had low sperm count and 33.33% had near normal sperm count. All patients were operated for bilateral varicocele and discharged. Follow-up semen analysis showed improvement and semen analysis became normal in 19.3% after six months, 21.05% after nine months and 36.84% after one year of surgery while 22.81% had no improvement even after one year of surgery. Thus, patients with bilateral varicocele having low sperm count showed improvement in sperm count after varicocele surgery and so infertile patients may become fertile after varicocele surgery
Tripled coincidence point theorems for a φ-contractive mapping in a complete metric space without the mixed g-monotone property
- Author
- A Amini-Harandi
- A Roldan
- A Roldan
- ACM Ran
- B Samet
- BS Choudhury
- D Guo
- E Karapinar
- H Aydi
- H Aydi
- H Aydi
- H Aydi
- H Aydi
- H Aydi
- H Aydi
- JJ Nieto
- JJ Nieto
- M Abbas
- M Abbas
- M Berzig
- M Borcut
- M Mursaleen
- N Hussain
- NV Luong
- P Charoensawan
- Phakdi Charoensawan
- R Batra
- RP Agarwal
- SA Mohiuddine
- SM Alsulami
- T Gnana Bhaskar
- V Berinde
- V Berinde
- V Berinde
- V Berinde
- V Lakshmikantham
- W Sintunavarat
- W Sintunavarat
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Comprehensive analyses of tumor immunity: implications for cancer immunotherapy
- Author
- A Mackensen
- AM Giacomo Di
- AR Abbas
- AR Abbas
- B Li
- B Li
- Bo Li
- CG Drake
- DM Pardoll
- E Tran
- Eric Severson
- G Bindea
- H Matsushita
- Haoquan Zhao
- Hui Shen
- J Galon
- Jean-Christophe Pignon
- Jesse Novak
- Jon C. Aster
- Jun S. Liu
- K Milne
- K Silina
- KA Hoadley
- L Bingle
- M Angelova
- M Rajasagi
- M Yadav
- MG Anitei
- MJ Smyth
- MS Rooney
- NA Mabbott
- P Sharma
- PA Prieto
- PC Tumeh
- Peng Jiang
- RD Schreiber
- RS Herbst
- Sabina Signoretti
- Scott Rodig
- SF Hussain
- SL Carter
- SM Mahmoud
- T Alvaro
- Taiwen Li
- TI Zack
- TY Shibuya
- WE Johnson
- WH Fridman
- X. Shirley Liu
- Y Wada
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Measuring routine childhood vaccination coverage in 204 countries and territories, 1980-2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1
- Author
- Ab Khan M
- Abady GG
- Abbas KM
- Abbasi SW
- Abbastabar H
- Abd-Allah F
- Abdoli A
- Abolhassani H
- Abosetugn AE
- Adabi M
- Adamu AA
- Adetokunboh OO
- Adnani QES
- Advani SM
- Afzal S
- Aghamir SMK
- Ahinkorah BO
- Ahmad S
- Ahmad T
- Ahmadi S
- Ahmed H
- Ahmed MB
- Akalu Y
- Aklilu A
- Akunna CJ
- Al Hamad H
- Al Montasir A
- Al-Eyadhy A
- Alahdab F
- Albano L
- Alemayehu Y
- Alene KA
- Alhassan RK
- Ali L
- Aljunid SM
- Almustanyir S
- Altirkawi KA
- Alvis-Guzman N
- Amu H
- Andrei CL
- Andrei T
- Ansar A
- Ansari-Moghaddam A
- Antonazzo IC
- Antony B
- Arab-Zozani M
- Arabloo J
- Artanti KD
- Arulappan J
- Awan AT
- Awoke MA
- Ayza MA
- Azarian G
- Azzam AY
- Babar Z-U-D
- Bach XT
- Balakrishnan S
- Banach M
- Bante SA
- Barnighausen TW
- Barqawi HJ
- Barrow A
- Bassat Q
- Bayarmagnai N
- Bekuma TT
- Belay HG
- Belgaumi UI
- Bhagavathula AS
- Bhandari D
- Bhardwaj N
- Bhardwaj P
- Bhaskar S
- Bhattacharyya K
- Bibi S
- Bijani A
- Biondi A
- Boloor A
- Braithwaite D
- Buonsenso D
- Butt ZA
- Camargos P
- Carreras G
- Carvalho F
- Castaneda-Orjuela CA
- Chakinala RC
- Charan J
- Chatterjee S
- Chattu SK
- Chattu VK
- Chowdhury FR
- Christopher DJ
- Chu D-T
- Chung S-C
- Cortesi PA
- Costa VM
- Couto RAS
- Dadras O
- Dagnew AB
- Dagnew B
- Dai X
- Dandona L
- Dandona R
- Darshan BB
- De Neve J-W
- Defo BK
- Derseh BT
- Desai R
- Desta AA
- Dhamnetiya D
- Dhimal M
- Dhimal ML
- Dianatinasab M
- Diaz D
- Djalalinia S
- Dorostkar F
- Edem B
- Edinur HA
- Eftekharzadeh S
- El Sayed I
- El-Jaafary S
- Elhadi M
- Elsharkawy A
- Enany S
- Erkhembayar R
- Esezobor CI
- Eskandarieh S
- Ezeonwumelu IJ
- Ezzikouri S
- Fares J
- Faris PS
- Feleke BE
- Ferede TY
- Fernandes E
- Fernandes JC
- Ferrara P
- Filip I
- Fischer F
- Francis MR
- Fukumoto T
- Fullman N
- Gad MM
- Gaidhane S
- Galles NC
- Gallus S
- Garg T
- Geberemariyam BS
- Gebre T
- Gebregiorgis BG
- Gebremedhin KB
- Gebremichael B
- Gessner BD
- Ghadiri K
- Ghafourifard M
- Ghashghaee A
- Giang TV
- Gilani SA
- Glushkova EV
- Golechha M
- Gonfa KB
- Gopalani SV
- Goudarzi H
- Gubari MIM
- Guo Y
- Gupta VB
- Gupta VK
- Gutierrez RA
- Haeuser E
- Halwani R
- Hamidi S
- Hanif A
- Haque S
- Harapan H
- Hargono A
- Hashi A
- Hassan S
- Hassanein MH
- Hassanipour S
- Hassankhani H
- Hay S
- Hayat K
- Hegazy M
- Heidari G
- Hezam K
- Holla R
- Hoque ME
- Hosseini M
- Hosseinzadeh M
- Hostiuc M
- Househ M
- Hsieh VC-R
- Huang J
- Humayun A
- Hussain R
- Hussein NR
- Ibitoye SE
- Ilesanmi OS
- Ilic IM
- Ilic MD
- Inamdar S
- Iqbal U
- Irham LM
- Irvani SSN
- Islam SMS
- Ismail NE
- Itumalla R
- Jha RP
- Joukar F
- Kabir A
- Kabir Z
- Kalhor R
- Kamal Z
- Kamande SM
- Kan FP
- Kandel H
- Kandel SN
- Karch A
- Kassahun G
- Kassebaum NJ
- Katoto PD
- Kelkay B
- Kengne AP
- Khader YS
- Khajuria H
- Khalil IA
- Khan EA
- Khan G
- Khan J
- Khan M
- Khang Y-H
- Khoja AT
- Khubchandani J
- Kim GR
- Kim MS
- Kim YJ
- Kimokoti RW
- Kisa A
- Kisa S
- Korshunov VA
- Kosen S
- Kulkarni V
- Kumar A
- Kumar GA
- Kumar N
- Kwarteng A
- La Vecchia C
- Lami FH
- Landires I
- Lasrado S
- Lassi ZS
- Lee H
- Lee YY
- Levi M
- Lewycka S
- Li S
- Lim SS
- Linh GV
- Liu PY
- Liu X
- Lobo SW
- Lopukhov PD
- Lozano R
- Makki A
- Malik AA
- Mansour-Ghanaei F
- Mansournia MA
- Mantovani LG
- Marks A
- Martins-Melo FR
- Matthews PC
- Medina JRC
- Mendoza W
- Menezes RG
- Mengesha EW
- Meretoja TJ
- Mersha AG
- Mesregah MK
- Mestrovic T
- Miazgowski B
- Milne GJ
- Mirica A
- Mirrakhimov EM
- Mirzaei HR
- Misra S
- Mithra P
- Moghadaszadeh M
- Mohamed TA
- Mohammad KA
- Mohammad Y
- Mohammadi M
- Mohammadian-Hafshejani A
- Mohammed A
- Mohammed S
- Mohapatra A
- Mokdad AH
- Molla MD
- Molokhia M
- Monasta L
- Moni MA
- Moore CE
- Moradi G
- Moradzadeh R
- Moraga P
- Mosser JF
- Mueller UO
- Munro SB
- Murray CJL
- Naghavi M
- Naimzada MD
- Naveed M
- Nayak BP
- Negoi I
- Nguyen J
- Nguyen TH
- Nikbakhsh R
- Ningrum DNA
- Nixon MR
- Nnaji CA
- Noubiap JJ
- Nunez-Samudio V
- Nwatah VE
- Oancea B
- Ochir C
- Ogbo FA
- Olagunju AT
- Olakunde BO
- Onwujekwe OE
- Otstavnov N
- Otstavnov SS
- Owolabi MO
- Padubidri JR
- Pakshir K
- Park E-C
- Pathak M
- Paudel R
- Pawar S
- Pereira J
- Peres MFP
- Perianayagam A
- Pinheiro M
- Pirestani M
- Podder V
- Polibin R
- Pollok RCG
- Postma MJ
- Pottoo FH
- Rabiee M
- Rabiee N
- Radfar A
- Rafiei A
- Rahimi-Movaghar V
- Rahman M
- Rahmani AM
- Rahmawaty S
- Rajesh A
- Ramirez DFB
- Ramshaw RE
- Ranasinghe P
- Rao CR
- Rao SJ
- Rashid TA
- Rathi P
- Rawaf DL
- Rawaf S
- Razek MMAE
- Renzaho AMN
- Rezaei N
- Rezai MS
- Rios-Blancas M
- Rogowski ELB
- Rolfe S
- Ronfani L
- Rwegerera GM
- Saad AM
- Sabour S
- Saddik B
- Saeb MR
- Saeed U
- Sahebkar A
- Sahraian MA
- Salam N
- Salih YA
- Salimzadeh H
- Samaei M
- Samy AM
- Sanabria J
- Sanmarchi F
- Santric-Milicevic MM
- Sartorius B
- Sarveazad A
- Sathian B
- Saute RL
- Sawhney M
- Saxena D
- Saxena S
- Sbarra AN
- Schipp MF
- Seidu A-A
- Seylani A
- Shaikh MA
- Shamsizadeh M
- Shetty PH
- Shigematsu M
- Shin JI
- Sidemo NB
- Singh A
- Singh JA
- Sinha S
- Skryabin VY
- Skryabina AA
- Soheili A
- Tadesse EG
- Tamiru AT
- Tan K-K
- Tekalegn Y
- Temsah M-H
- Thakur B
- Thapar R
- Thavamani A
- Tobe-Gai R
- Tohidinik HR
- Tovani-Palone MR
- Traini E
- Tripathi M
- Tsegaye B
- Tsegaye GW
- Ullah A
- Ullah S
- Ullah S
- Unim B
- Updike RL
- Vacante M
- Velazquez DZ
- Vo B
- Vollmer S
- Waheed Y
- Winkler AS
- Wiysonge CS
- Yigit V
- Yirdaw BW
- Yon DK
- Yonemoto N
- Yu C
- Yuce D
- Yunusa I
- Zaki MES
- Zamani M
- Zamanian M
- Zewdie DT
- Zhang Z-J
- Zhong C
- Zumla A
- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 07/08/2021
- Field of study
Background: Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time. //
Methods: For this analysis we collated 55 326 country-specific, cohort-specific, year-specific, vaccine-specific, and dose-specific observations of routine childhood vaccination coverage between 1980 and 2019. Using spatiotemporal Gaussian process regression, we produced location-specific and year-specific estimates of 11 routine childhood vaccine coverage indicators for 204 countries and territories from 1980 to 2019, adjusting for biases in country-reported data and reflecting reported stockouts and supply disruptions. We analysed global and regional trends in coverage and numbers of zero-dose children (defined as those who never received a diphtheria-tetanus-pertussis [DTP] vaccine dose), progress towards GVAP targets, and the relationship between vaccine coverage and sociodemographic development. //
Findings: By 2019, global coverage of third-dose DTP (DTP3; 81·6% [95% uncertainty interval 80·4–82·7]) more than doubled from levels estimated in 1980 (39·9% [37·5–42·1]), as did global coverage of the first-dose measles-containing vaccine (MCV1; from 38·5% [35·4–41·3] in 1980 to 83·6% [82·3–84·8] in 2019). Third-dose polio vaccine (Pol3) coverage also increased, from 42·6% (41·4–44·1) in 1980 to 79·8% (78·4–81·1) in 2019, and global coverage of newer vaccines increased rapidly between 2000 and 2019. The global number of zero-dose children fell by nearly 75% between 1980 and 2019, from 56·8 million (52·6–60·9) to 14·5 million (13·4–15·9). However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. Only 11 countries and territories were estimated to have reached the national GVAP target of at least 90% coverage for all assessed vaccines in 2019. //
Interpretation: After achieving large gains in childhood vaccine coverage worldwide, in much of the world this progress was stalled or reversed from 2010 to 2019. These findings underscore the importance of revisiting routine immunisation strategies and programmatic approaches, recentring service delivery around equity and underserved populations. Strengthening vaccine data and monitoring systems is crucial to these pursuits, now and through to 2030, to ensure that all children have access to, and can benefit from, lifesaving vaccines
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adelson JD
- Adeoye AM
- Adetokunboh OO
- Adham D
- Advani SM
- Afarideh M
- Afshari M
- Afshin A
- Agardh EE
- Agarwal G
- Agasthi P
- Agesa KM
- Aghaali M
- Aghamir SMK
- Agrawal A
- Ahmad T
- Ahmadi A
- Ahmadi K
- Ahmadi M
- Ahmadieh H
- Ahmadpour E
- Ahmed MB
- Aji B
- Akalu TY
- Akinyemi RO
- Akinyemiju T
- Akombi B
- Akunna CJ
- Al-Aly Z
- Al-Mekhlafi HM
- Al-Raddadi RM
- Alahdab F
- Alam K
- Alam N
- Alam S
- Alam T
- Alanezi FM
- Alanzi TM
- Albertson SB
- Alcalde-Rabanal JE
- Alema NM
- Alemu BW
- Alemu YM
- Alhabib KF
- Alhassan RK
- Ali M
- Ali S
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Alla F
- Allebeck P
- Almadi MAH
- Almasi A
- Almasi-Hashiani A
- Almasri NA
- Almulhim AM
- Alonso J
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- Alumran AK
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- Alvis-Zakzuk NJ
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- Amare B
- Amini S
- Amini-Rarani M
- Aminorroaya A
- Amiri F
- Amit AML
- Amugsi DA
- Amul GGH
- Anbesu EW
- Ancuceanu R
- Anderlini D
- Anderson JA
- Andrei CL
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- Angus C
- Anjomshoa M
- Ansari F
- Ansari I
- Ansari-Moghaddam A
- Antonazzo IC
- Antonio CAT
- Antony CM
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- Anvari D
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- Arabloo J
- Aravkin AY
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- Avokpaho EFGA
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- Callender CSKH
- Camera LA
- Campos-Nonato IR
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- Collins EL
- Comfort H
- Compton K
- Conti S
- Cooper OR
- Corso B
- Cortesi PA
- Costa VM
- Cousin E
- Cowden RG
- Cowie BC
- Cromwell EA
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- Cross M
- Crowe CS
- Cruz JA
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- da Silva DD
- Dahlawi SMA
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- Dai H
- Damasceno AAM
- Damiani G
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- Danielsson A-K
- Dargan PI
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- Darwesh AM
- Daryani A
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- Davila-Cervantes CA
- Davis AC
- Davitoiu DV
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- De Neve J-W
- Dean FE
- DeCleene NK
- Deen A
- Defo BK
- Degenhardt L
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- Dellavalle RP
- Demeke FM
- Demoz GT
- Demsie DG
- Denova-Gutierrez E
- Dereje ND
- Deribe K
- Dervenis N
- Desai R
- Desalew A
- Dessie GA
- Deuba K
- Dharmaratne SD
- Dhungana GP
- Dianatinasab M
- Diaz D
- Dichgans M
- Didarloo A
- Dingels ZV
- Dippenaar IN
- Dirac MA
- Djalalinia S
- Do HT
- Dokova K
- Doku DT
- Dolecek C
- Dolgert AJ
- Dorostkar F
- Doshi CP
- Doshi PP
- Doshmangir L
- Douiri A
- Doxey MC
- Doyle KE
- Driscoll TR
- Dubljanin E
- Dunachie SJ
- Duncan BB
- Duraes AR
- Eagan AW
- Ebrahimi H
- Edvardsson D
- Effiong A
- Ehrlich JR
- El Nahas N
- El Sayed I
- El Tantawi M
- El-Jaafary SI
- Elbarazi I
- Elgendy IY
- Elhabashy HR
- Elsharkawy A
- Elyazar IRF
- Emamian MH
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- Wolfe CDA
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- Wondmieneh AB
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- Wu A-M
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- Wu J
- Wunrow HY
- Xie Y
- Xu G
- Xu R
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- Yamada T
- Yamagishi K
- Yaminfirooz M
- Yano Y
- Yaya S
- Yazdi-Feyzabadi V
- Yearwood JA
- Yeheyis TY
- Yeshitila YG
- Yilgwan CS
- Yilma MT
- Yip P
- Yonemoto N
- Yoon S-J
- York HW
- Younis MZ
- Younker TP
- Yousefi B
- Yousefi Z
- Yousefifard M
- Yousefinezhadi T
- Yousuf AY
- Yu C
- Yu Y
- Yuan C-W
- Yuce D
- Yusefzadeh H
- Zadey S
- Zahabi SS
- Zaidi SS
- Zaki L
- Zaki MES
- Zakzuk J
- Zamani M
- Zamanian M
- Zandian H
- Zangeneh A
- Zarafshan H
- Zastrozhin MS
- Zewdie KA
- Zhang J
- Zhang Y
- Zhang Z-J
- Zhao JT
- Zhao X-JG
- Zhao Y
- Zheleva B
- Zheng P
- Zhou M
- Zhu C
- Ziapour A
- Zimsen SRM
- Zlavog BS
- Zodpey S
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/10/2020
- Field of study
Five insights from the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
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- Publication venue
- Publication date
- 01/01/2020
- Field of study
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.Peer reviewe
Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.
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- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators
- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators, Nepogodiev, D
- Stechman M
- Stewart D
- Stewart E
- Stewart H
- Stewart R
- Stickler E
- Stoddart MT
- Stokes E
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- Strang S
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- Stringfellow TD
- Stubbing-Moore A
- Sturrock S
- Subar D
- Subratty SM
- Sukirthan N
- Sukumar S
- Sulaiman SK
- Sultan S
- Sun L
- Sundaram K
- Suresh R
- Suresh S
- Sureshkumar A
- Suri A
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- Swan A
- Swan I
- Swaray A
- Swartbol T
- Symons L
- Szczap A
- Szuman A
- Tailor S
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- Tam JP
- Tan CY
- Tan KL
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- Tan TSE
- Tang A
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- Taribagil P
- Tariq A
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- Tayeh S
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- Taylor R
- Taylor Z
- Telfer R
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- Teo R
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- Thakrar D
- Thatcher A
- Theodoropoulou K
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- Worsfold M
- Wright OW
- Wright R
- Wright S
- Wroe N
- Wynell-Mayow W
- Xu Y
- Yahaya AA
- Yalamarthi S
- Yang DD
- Yang N
- Yap J
- Yardimci E
- Yarham E
- Yasin IH
- Yasin T
- Yates J
- Ye W
- Yeo A
- Yeoh T
- Yeung J
- Yin ZD
- Yip J
- Yoganayagam N
- Yogeswara T
- York J
- Yousaf A
- Youssef H
- Yu T
- Yule A
- Zaat S
- Zanichelli D
- Zaver V
- Zeng R
- Zhang Y
- Zheleniakova T
- Zhu Y
- Zornoza A
- Zubikarai G
- Zulkifli A
- Zuzarte L
- Publication venue
- 'Wiley'
- Publication date
- 18/05/2018
- Field of study
Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability
The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Aali Amirali
- Abbas Qamar
- Abbasi Behzad
- Abbasi-Kangevari Mohsen
- Abbasi-Kangevari Zeinab
- Abbastabar Hedayat
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed Abdelwahab
- Abdoli Gholamreza
- Abdulkader Rizwan Suliankatchi
- Abdulkadir Hanan Abdulkadir
- Abedi Aidin
- Abegaz Kedir Hussein
- Abidi Hassan
- Aboagye Richard Gyan
- Abolhassani Hassan
- Absalan Abdorrahim
- Abtew Yonas Derso
- Abu-Gharbieh Eman
- Achappa Basavaprabhu
- Acheson Alistair R
- Acuna Juan Manuel
- Addison Daniel
- Addo Isaac Yeboah
- Adegboye Oyelola A
- Adesina Miracle Ayomikun
- Adnan Mohammad
- Adnani Qorinah Estiningtyas Sakilah
- Advani Shailesh M
- Afrin Sumia
- Afzal Muhammad Sohail
- Aggarwal Manik
- Ahinkorah Bright Opoku
- Ahmad Araz Ramazan
- Ahmad Rizwan
- Ahmad Sajjad
- Ahmad Sohail
- Ahmadi Sepideh
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Muktar Beshir
- Aiman Wajeeha
- Ajami Marjan
- Akalu Gizachew Taddesse
- Akbarzadeh-Khiavi Mostafa
- Aklilu Addis
- Akonde Maxwell
- Akunna Chisom Joyqueenet
- Al-Hanawi Mohammed Khaled
- Al-Maweri Sadeq Ali Ali
- Al-Raddadi Rajaa M
- Al-Rifai Rami H Hani
- Al-Sabah Salman Khalifah
- Al-Tammemi Ala'a B
- Alahdab Fares
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Alessy Saleh Ali
- Algammal Abdelazeem M
- Alhassan Robert Kaba
- Ali Adel Hajj
- Ali Beriwan Abdulqadir
- Ali Hiwa Abubaker
- Ali Liaqat
- Ali Syed Shujait
- Alimohamadi Yousef
- Alipour Vahid
- Aljunid Syed Mohamed
- Alkhayyat Motasem
- Almustanyir Sami
- Alonso Nivaldo
- Alqalyoobi Shehabaldin
- Altawalah Haya
- Alvis-Guzman Nelson
- Amare Firehiwot
- Ameyaw Edward Kwabena
- Amirzade-Iranaq Mohammad Hosein
- Amu Hubert
- Amusa Ganiyu Adeniyi
- Ancuceanu Robert
- Anderson Jason A
- Animut Yaregal Animut
- Anoushiravani Amir
- Anoushirvani Ali Arash
- Ansari-Moghaddam Alireza
- Ansha Mustafa Geleto
- Antony Benny
- Antwi Maxwell Hubert
- Anwar Sumadi Lukman
- Anwer Razique
- Anyasodor Anayochukwu Edward
- Arab-Zozani Morteza
- Arabloo Jalal
- Aremu Olatunde
- Argaw Ayele Mamo
- Ariffin Hany
- Aripov Timur
- Arshad Muhammad
- Artaman Al
- Arulappan Judie
- Aruleba Raphael Taiwo
- Aryannejad Armin
- Asaad Malke
- Asemahagn Mulusew A
- Asemi Zatollah
- Asghari-Jafarabadi Mohammad
- Ashraf Tahira
- Assadi Reza
- Athar Mohammad
- Athari Seyyed Shamsadin
- Atout Maha Moh'd Wahbi
- Attia Sameh
- Aujayeb Avinash
- Ausloos Marcel
- Avila-Burgos Leticia
- Avval Atlas Haddadi
- Awedew Atalel Fentahun
- Awoke Mamaru Ayenew
- Awoke Tewachew
- Ayana Tegegn Mulatu
- Ayen Solomon Shitu
- Azadi Davood
- Azadnajafabad Sina
- Azami-Aghdash Saber
- Azanaw Melkalem Mamuye
- Azangou-Khyavy Mohammadreza
- Azizi Hosein
- Azzam Ahmed YY
- Babajani Amirhesam
- Badar Muhammad
- Badiye Ashish D
- Baghcheghi Nayereh
- Bagheri Nader
- Bagherieh Sara
- Bahadory Saeed
- Baig Atif Amin
- Bain Luchuo Engelbert
- Baker Jennifer L
- Bakhtiari Ahad
- Bakshi Ravleen Kaur
- Banach Maciej
- Banerjee Indrajit
- Bardhan Mainak
- Barone-Adesi Francesco
- Barra Fabio
- Barrow Amadou
- Bashir Nasir Z
- Bashiri Azadeh
- Basu Saurav
- Batiha Abdul-Monim Mohammad
- Begum Aeysha
- Bekele Alehegn Bekele
- Belay Alemayehu Sayih
- Belete Melaku Ashagrie
- Belgaumi Uzma Iqbal
- Bell Arielle Wilder
- Belo Luis
- Benzian Habib
- Berhie Alemshet Yirga
- Bermudez Amiel Nazer C
- Bernabe Eduardo
- Bhagavathula Akshaya Srikanth
- Bhala Neeraj
- Bhandari Bharti Bhandari
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhattacharyya Krittika
- Bhojaraja Vijayalakshmi S
- Bhuyan Soumitra S
- Bibi Sadia
- Bicer Burcu Kucuk
- Bilchut Awraris Hailu
- Bintoro Bagas Suryo
- Biondi Antonio
- Birega Mesfin Geremaw Birega
- Birhan Habitu Eshetu
- Bjørge Tone
- Blyuss Oleg
- Bodicha Belay Boda Abule
- Bohan Phillip M Kemp
- Bolla Srinivasa Rao
- Boloor Archith
- Bosetti Cristina
- Braithwaite Dejana
- Brauer Michael
- Brenner Hermann
- Briko Andrey Nikolaevich
- Briko Nikolay Ivanovich
- Buchanan Christina Maree
- Bulamu Norma B
- Bustamante-Teixeira Maria Teresa
- Butt Muhammad Hammad
- Butt Nadeem Shafique
- Butt Zahid A
- Cao Chao
- Cao Yin
- Carreras Giulia
- Carvalho Márcia
- Cembranel Francieli
- Cerin Ester
- Chakraborty Promit Ananyo
- Chandrasekar Viveksandeep Thoguluva
- Charalampous Periklis
- Chattu Vijay Kumar
- Chimed-Ochir Odgerel
- Chirinos-Caceres Jesus Lorenzo
- Cho Daniel Youngwhan
- Cho William CS
- Christopher Devasahayam J
- Chu Dinh-Toi
- Chukwu Isaac Sunday
- Cohen Aaron J
- Collaborators GBD 2019 Cancer Risk Factors
- Compton Kelly
- Conde Joao
- Cortés Sandra
- Costa Vera Marisa
- Cruz-Martins Natália
- Culbreth Garland T
- Cámera Luis Alberto
- Dadras Omid
- Dagnaw Fentaw Teshome
- Dahlawi Saad MA
- Dai Xiaochen
- Dandona Lalit
- Dandona Rakhi
- Daneshpajouhnejad Parnaz
- Danielewicz Anna
- Dao An Thi Minh
- Darwesh Aso Mohammad
- Das Saswati
- Davitoiu Dragos Virgil
- De la Hoz Fernando Pio
- Debela Sisay Abebe
- Dehghan Azizallah
- Dehkordi Javad Javad Aminian
- Demisse Biniyam
- Demisse Fitsum Wolde
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- Woldemariam Melat
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- Xiao Hong
- Xu Rixing
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- Xu Xiaoyue
- Yadav Lalit
- Yang Lin
- Yazdanpanah Fereshteh
- Yeshaw Yigizie
- Yismaw Yazachew
- Yonemoto Naohiro
- Younis Mustafa Z
- Yousefi Zabihollah
- Yousefian Fatemeh
- Yu Chuanhua
- Yu Yong
- Yunusa Ismaeel
- Zahir Mazyar
- Zaki Nazar
- Zaman Burhan Abdullah
- Zangiabadian Moein
- Zare Fariba
- Zare Iman
- Zareshahrabadi Zahra
- Zarrintan Armin
- Zastrozhin Mikhail Sergeevich
- Zeineddine Mohammad A
- Zhang Dongyu
- Zhang Jianrong
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhou Linghui
- Zodpey Sanjay
- Zoladl Mohammad
- Šekerija Mario
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Background Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe
The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Aali A
- Ab Khan M
- Abbas Q
- Abbasi B
- Abbasi-Kangevari M
- Abbasi-Kangevari Z
- Abbastabar H
- Abd-Elsalam S
- Abdelmasseh M
- Abdelwahab AA
- Abdoli G
- Abdulkader RS
- Abdulkadir HA
- AbdulmuhsinMohammad K
- Abedi A
- Abegaz KH
- Abidi H
- Aboagye RG
- Abolhassani H
- Absalan A
- Abtew YD
- Abu-Gharbieh E
- Achappa B
- Acheson AR
- Acuna JM
- Addison D
- Addo IY
- Adegboye OA
- Adesina MA
- Adnan M
- Adnani QES
- Advani SM
- Afrin S
- Afzal MS
- Aggarwal M
- Ahinkorah BO
- Ahmad AR
- Ahmad R
- Ahmad S
- Ahmadi S
- Ahmed H
- Ahmed LA
- Ahmed MB
- Aiman W
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- Sitas F
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- Socea B
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- Soodejani MT
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- Soshnikov S
- Sotoudeh H
- Sowe A
- Sufiyan MB
- Suk R
- Suleman M
- Sultana S
- Sur D
- Swamy SN
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- Szacska M
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- Tahbaz SV
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- Tekalegn Y
- Tesfay FH
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- Ticoalu JHV
- Tiyuri A
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- Toroudi HP
- Touvier M
- Tovani-Palone MR
- Traini E
- Tran KB
- Tran MTN
- Tripathy JP
- Ukke GG
- Ullah I
- Ullah S
- Unnikrishnan B
- Vacante M
- Vaezi M
- Valdez PR
- Vardavas C
- Varniab ZS
- Varthya SB
- Vaziri S
- Velazquez DZ
- Veroux M
- Villeneuve PJ
- Violante FS
- Vladimirov SK
- Vlassov V
- Vo B
- Vos T
- Vu LG
- Wadood AW
- Waheed Y
- Walde MT
- Wamai RG
- Wang C
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- Waris A
- Westerman R
- Wickramasinghe ND
- Woldemariam M
- Woldu B
- Xiao H
- Xu R
- Xu S
- Xu X
- Yadav L
- Yang L
- Yazdanpanah F
- Yeshaw Y
- Yismaw Y
- Yonemoto N
- Younis MZ
- Yousefi Z
- Yousefian F
- Yu C
- Yu Y
- Yunusa I
- Zahir M
- Zaki N
- Zaman BA
- Zangiabadian M
- Zare F
- Zare I
- Zareshahrabadi Z
- Zarrintan A
- Zastrozhin MS
- Zeineddine MA
- Zhang D
- Zhang J
- Zhang Y
- Zhang Z-J
- Zhou L
- Zodpey S
- Zoladl M
- Publication venue
- Publication date
- 20/08/2022
- Field of study
Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.
- Author
- Abantanga F
- Abbas M
- Abbo O
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elrasoul Y
- Abdallah E
- Abdel-Wahab NYE
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelkader M
- Abdelkareem A
- Abdelraheim M
- Abdelshafy M
- Abdulgawad M
- Abdullah AAN
- Abdullah NAN
- Abebe NS
- Abebe NS
- Aber A
- Abington E
- Aboarab A
- Aboraya M
- Aboraya M
- Abouelnasr A
- Abouzahra A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abudeeb H
- Abuseif M
- Acharya P
- Adams R
- Adebanjo A
- Adekoya A
- Adel A
- Adel A
- Ademuyiwa A
- Ademuyiwa AO
- Adeniran J
- Adeniyi A
- Adesanya O
- Adesina A
- Adesuyi A
- Adeyeye A
- Adham W
- Afandy A
- Afifi AM
- Afzal M
- Agalianos C
- Agarwal A
- Agius M
- Aguilar-Jimenez J
- Aguilera M
- Aguilera O
- Ahlqvist S
- Ahmed A
- Ahmed EA
- Ahmed H
- Ahmed SM
- Aigrain Y
- Ajao AE
- Akeel N
- Akhtar M
- Al Awwad S
- Al-Aarag AA-R
- Al-Azraqi IAA
- Al-Faifi JJ
- Al-Hameedi HII
- Al-Hasani RKMJ
- Al-Mallah A
- Al-Mousa M
- Al-Nahrawi S
- Al-Obaedi O
- Al-shammari A
- Alahmady O
- Alakaloko F
- Alamoudi U
- Albeladi B
- Aldalaq A
- Aldhafeeri S
- Aledrisy M
- Alfarsi MA
- Alghamdi B
- Alghamdi M
- Algohary O
- Alhabli I
- Alhendy M
- Ali A
- Ali A
- Ali H
- Ali SS
- Alimi Q
- Aljiffry M
- Aljohani E
- Aljohani S
- Alkammash A
- Alkhabbaz D
- Alkhouri M
- Allam M
- Allegri A
- Allen JLY
- Allott R
- Almallah A
- Almoflihi A
- Almuallem S
- Almy J
- Alnawam E
- Alnuqaydan SA
- Alomar IN
- Alqahtani E
- Alrahawy M
- Alrajraji M
- Alrifaie A
- AlRowais M
- Alsaggaf M
- Alsaggaf MU
- Altaf A
- Altamimi A
- Althwainy A
- Altoe F
- Altwigry AM
- Alvarado Jaramillo R
- Alvarez Barreda LM
- Alwafai MG
- Aly AK
- Alyami R
- AlYoussef I
- Alzahrani M
- Alzayat T
- Amandito R
- Ambrozeviciute V
- Ameen M
- Amer MA
- Amin J
- Ammar M
- Ammar MS
- Amreia M
- Anandkumar D
- Anderson D
- Anderson R
- Anderson-Knight H
- Andersson L
- Andres Garcia-Marin J
- Ansaloni L
- Antar S
- Anthoulakis C
- Anwar AW
- Anwer W
- Anyanwu L-J
- Aql S
- Arachchi PP
- Arachchige LAJJ
- Aranzabal Durand SY
- Araujo R
- Ardley R
- Arenas A
- Arevalo Azmitia JR
- Arias Pacheco RD
- Arman S
- Arnaud AP
- Arnaud AP
- Arroyo Basto CA
- Arulampalam T
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- Watson NFS
- Watts A
- Weber B
- Weber P
- Weinstein MS
- Wheeler J
- Whewell H
- White T
- Wild JRL
- Williams E
- Williams G
- Williams O
- Williamson A
- Wilson A
- Wilson MSJ
- Wilson MSJ
- Winstanley J
- Witherspoon P
- Wogensen F
- Woin E
- Wold TB
- Wolf B
- Wondimu S
- Wong CS
- Woodward H
- Worku M
- Wredberg C
- Wright NJ
- Xerri T
- Yallop L
- Yaseen T
- Yaseen TM
- Yavuz MA
- Yee J
- Yeo LS
- Yeung ENW
- Yong CO
- Youssef D
- Youssef H
- Youssif JH
- Zachariades D-C
- Zakir M
- Zalabia MF
- Zamarin K
- Zani A
- Zanini N
- Zapata Ponze De Leon M
- Zapata Ponze De Leon M
- Zardab A
- Zegarra S
- Zeidan S
- Zelada Alvarez II
- Zerihun AB
- Zhang Z
- Zheng F
- Zidan H
- Zidan M
- Ziff O
- Zikry M
- Zil-E-Ali A
- Zilinskas J
- Zilinskiene R
- Zimmermann EF
- Zuber M
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. METHODS: This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6 months was conducted. Follow-up lasted 30 days. RESULTS: 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33-4.99, p = 0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76-2.52, p = 0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42-0.71, p < 0.001) and SSIs (OR 0.22, 95% CI 0.14-0.33, p < 0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11-0.44) and SSI (OR 0.21 95% CI 0.09-0.45). CONCLUSION: A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. TRIAL REGISTRATION: NCT02179112
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