10 research outputs found
Efficient Ugi reactions in an aqueous vesicle system
No full textA new, alternative route for the synthesis of a variety of α-aminoacyl amides via the four-component Ugi reaction in the presence of different types of surfactants was investigated. The best results were obtained if the reaction was carried out in the presence of either didodecyldimethylammonium bromide (DDAB) vesicles or Triton X-100 micelles. The presence of vesicles or micelles in these systems was confirmed by applying dynamic light scattering (DLS) and fluorescence measurements. Additionally, detailed studies of the dependence on the concentration of the two surfactants and on their reusability were performed. The obtained results demonstrate the beneficial effect aqueous surfactant systems may have on the course of the Ugi-multicomponent reaction.ISSN:2046-206
Synthesis of (E)-α,β-unsaturated carboxylic esters derivatives from cyanoacetic acid via promiscuous enzyme-promoted cascade esterification/Knoevenagel reaction
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Enzymatic Tandem Approach to Knoevenagel Condensation of Acetaldehyde with Acidic Methylene Compounds in Organic Media
No full textThe studies on chemoselective promiscuous activity of hydrolases on acylals transformations
No full textAntibacterial pyrrolidinyl and piperidinyl substituted 2,4-diacetylphloroglucinols from Pseudomonas protegens UP46
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