129,959 research outputs found
Airborne chemical sensing with mobile robots
Airborne chemical sensing with mobile robots has been an active research areasince the beginning of the 1990s. This article presents a review of research work in this field,including gas distribution mapping, trail guidance, and the different subtasks of gas sourcelocalisation. Due to the difficulty of modelling gas distribution in a real world environmentwith currently available simulation techniques, we focus largely on experimental work and donot consider publications that are purely based on simulations
Physical constraints on accuracy and persistence during breast cancer cell chemotaxis
Directed cell motion in response to an external chemical gradient occurs in
many biological phenomena such as wound healing, angiogenesis, and cancer
metastasis. Chemotaxis is often characterized by the accuracy, persistence, and
speed of cell motion, but whether any of these quantities is physically
constrained by the others is poorly understood. Using a combination of theory,
simulations, and 3D chemotaxis assays on single metastatic breast cancer cells,
we investigate the links among these different aspects of chemotactic
performance. In particular, we observe in both experiments and simulations that
the chemotactic accuracy, but not the persistence or speed, increases with the
gradient strength. We use a random walk model to explain this result and to
propose that cells' chemotactic accuracy and persistence are mutually
constrained. Our results suggest that key aspects of chemotactic performance
are inherently limited regardless of how favorable the environmental conditions
are
Sensing array for coherence analysis of modulated aquatic chemical plumes
An electrochemical sensor array can provide information about the spatial and temporal distribution of chemicals in liquid turbulent plumes. Planar laser induced fluorescence (PLIF) and amperometric sensor arrays were used to record signals from modulated chemical plumes released into a recirculating aquatic flume. Coherence analysis was applied to extract the frequency components contained in the sensor response. Effects due to release distance, modulation frequency, and array orientation were investigated. This study has demonstrated that frequency encoded information can be extracted from a turbulent chemical plume using an array of amperometric sensors with optimized three-dimensional geometry and tuning.M.S.Committee Chair: Janata, Jiri; Committee Member: Lyon, Andrew; Committee Member: Weissburg, Mar
Chemical event tracking using a low-cost wireless chemical sensing network
A recently developed low-cost light emitting diode (LED) chemical sensing technique is integrated with a Mica2Dot wireless communications platform to form a deployable wireless chemical event indicator network. The operation of the colorimetric sensing node has been evaluated to determine its reproducibility and limit of detection for an acidic airborne contaminant. A test-scale network of five similar chemical sensing nodes is deployed in a star communication topology at fixed points within a custom built Environmental Sensing Chamber (ESC). Presented data sets collected from the deployed wireless chemical sensor network (WCSN) show that during an acidic event scenario it is possible to track the plume speed and direction, and estimate the concentration of chemical plume by examining the collective sensor data relative to individual sensor node location within the monitored environment
Nanoscale Sensing Using Point Defects in Single-Crystal Diamond: Recent Progress on Nitrogen Vacancy Center-Based Sensors
Individual, luminescent point defects in solids so called color centers are
atomic-sized quantum systems enabling sensing and imaging with nanoscale
spatial resolution. In this overview, we introduce nanoscale sensing based on
individual nitrogen vacancy (NV) centers in diamond. We discuss two central
challenges of the field: First, the creation of highly-coherent, shallow NV
centers less than 10 nm below the surface of single-crystal diamond. Second,
the fabrication of tip-like photonic nanostructures that enable efficient
fluorescence collection and can be used for scanning probe imaging based on
color centers with nanoscale resolution.Comment: Overview paper on sensing with defects in diamond, we focus on
creation of shallow NV centers and nanostructures, Final Version published in
Crystal
Increasing pattern recognition accuracy for chemical sensing by evolutionary based drift compensation
Artificial olfaction systems, which mimic human olfaction by using arrays of gas chemical sensors combined with pattern recognition methods, represent a potentially low-cost tool in many areas of industry such as perfumery, food and drink production, clinical diagnosis, health and safety, environmental monitoring and process control. However, successful applications of these systems are still largely limited to specialized laboratories. Sensor drift, i.e., the lack of a sensor's stability over time, still limits real in dustrial setups. This paper presents and discusses an evolutionary based adaptive drift-correction method designed to work with state-of-the-art classification systems. The proposed approach exploits a cutting-edge evolutionary strategy to iteratively tweak the coefficients of a linear transformation which can transparently correct raw sensors' measures thus mitigating the negative effects of the drift. The method learns the optimal correction strategy without the use of models or other hypotheses on the behavior of the physical chemical sensors
Acoustic Communication for Medical Nanorobots
Communication among microscopic robots (nanorobots) can coordinate their
activities for biomedical tasks. The feasibility of in vivo ultrasonic
communication is evaluated for micron-size robots broadcasting into various
types of tissues. Frequencies between 10MHz and 300MHz give the best tradeoff
between efficient acoustic generation and attenuation for communication over
distances of about 100 microns. Based on these results, we find power available
from ambient oxygen and glucose in the bloodstream can readily support
communication rates of about 10,000 bits/second between micron-sized robots. We
discuss techniques, such as directional acoustic beams, that can increase this
rate. The acoustic pressure fields enabling this communication are unlikely to
damage nearby tissue, and short bursts at considerably higher power could be of
therapeutic use.Comment: added discussion of communication channel capacity in section
Distributed Control of Microscopic Robots in Biomedical Applications
Current developments in molecular electronics, motors and chemical sensors
could enable constructing large numbers of devices able to sense, compute and
act in micron-scale environments. Such microscopic machines, of sizes
comparable to bacteria, could simultaneously monitor entire populations of
cells individually in vivo. This paper reviews plausible capabilities for
microscopic robots and the physical constraints due to operation in fluids at
low Reynolds number, diffusion-limited sensing and thermal noise from Brownian
motion. Simple distributed controls are then presented in the context of
prototypical biomedical tasks, which require control decisions on millisecond
time scales. The resulting behaviors illustrate trade-offs among speed,
accuracy and resource use. A specific example is monitoring for patterns of
chemicals in a flowing fluid released at chemically distinctive sites.
Information collected from a large number of such devices allows estimating
properties of cell-sized chemical sources in a macroscopic volume. The
microscopic devices moving with the fluid flow in small blood vessels can
detect chemicals released by tissues in response to localized injury or
infection. We find the devices can readily discriminate a single cell-sized
chemical source from the background chemical concentration, providing
high-resolution sensing in both time and space. By contrast, such a source
would be difficult to distinguish from background when diluted throughout the
blood volume as obtained with a blood sample
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