1,869 research outputs found
Discrete-Event Modeling of a High-Performance Computing Cluster with Service Rate Control
We present a stochastic recursion based discrete-event model of a high-performance computing cluster with service rate switching capabilities. The model is easily adopted to many common settings of modern supercomputers, such as specific scheduling disciplines and various control policies. We also provide some illustrative numerical experiments and discuss further generalizations of the model
Preventive antibiotic treatment of calves: emergence of dysbiosis causing propagation of obese state-associated and mobile multidrug resistance-carrying bacteria
In agriculture, antibiotics are used for the treatment and prevention of livestock disease. Antibiotics perturb the bacterial gut composition but the extent of these changes and potential consequences for animal and human health is still debated. Six calves were housed in a controlled environment. Three animals received an injection of the antibiotic florfenicol (Nuflor), and three received no treatment. Faecal samples were collected at 0, 3 and 7 days, and bacterial communities were profiled to assess the impact of a therapy on the gut microbiota. Phylogenetic analysis (16S‐rDNA) established that at day 7, antibiotic‐treated microbiota showed a 10‐fold increase in facultative anaerobic Escherichia spp, a signature of imbalanced microbiota, dysbiosis. The antibiotic resistome showed a high background of antibiotic resistance genes, which did not significantly change in response to florfenicol. However, the maintenance of Escherichia coli plasmid‐encoded quinolone, oqxB and propagation of mcr‐2, and colistin resistance genes were observed and confirmed by Sanger sequencing. The microbiota of treated animals was enriched with energy harvesting bacteria, common to obese microbial communities. We propose that antibiotic treatment of healthy animals leads to unbalanced, disease‐ and obese‐related microbiota that promotes growth of E. coli carrying resistance genes on mobile elements, potentially increasing the risk of transmission of antibiotic resistant bacteria to humans
Broken symmetry states and divergent resistance in suspended bilayer graphene
Graphene [1] and its bilayer have generated tremendous excitement in the
physics community due to their unique electronic properties [2]. The intrinsic
physics of these materials, however, is partially masked by disorder, which can
arise from various sources such as ripples [3] or charged impurities [4].
Recent improvements in quality have been achieved by suspending graphene flakes
[5,6], yielding samples with very high mobilities and little charge
inhomogeneity. Here we report the fabrication of suspended bilayer graphene
devices with very little disorder. We observe fully developed quantized Hall
states at magnetic fields of 0.2 T, as well as broken symmetry states at
intermediate filling factors , , and . The
devices exhibit extremely high resistance in the state that grows
with magnetic field and scales as magnetic field divided by temperature. This
resistance is predominantly affected by the perpendicular component of the
applied field, indicating that the broken symmetry states arise from many-body
interactions.Comment: 23 pages, including 4 figures and supplementary information; accepted
to Nature Physic
The Dynamics of Protest Recruitment through an Online Network
The recent wave of mobilizations in the Arab world and across Western countries has generated much discussion on how digital media is connected to the diffusion of protests. We examine that connection using data from the surge of mobilizations that took place in Spain in May 2011. We study recruitment patterns in the Twitter network and find evidence of social influence and complex contagion. We identify the network position of early participants (i.e. the leaders of the recruitment process) and of the users who acted as seeds of message cascades (i.e. the spreaders of information). We find that early participants cannot be characterized by a typical topological position but spreaders tend to be more central in the network. These findings shed light on the connection between online networks, social contagion, and collective dynamics, and offer an empirical test to the recruitment mechanisms theorized in formal models of collective action
Application of Graphene within Optoelectronic Devices and Transistors
Scientists are always yearning for new and exciting ways to unlock graphene's
true potential. However, recent reports suggest this two-dimensional material
may harbor some unique properties, making it a viable candidate for use in
optoelectronic and semiconducting devices. Whereas on one hand, graphene is
highly transparent due to its atomic thickness, the material does exhibit a
strong interaction with photons. This has clear advantages over existing
materials used in photonic devices such as Indium-based compounds. Moreover,
the material can be used to 'trap' light and alter the incident wavelength,
forming the basis of the plasmonic devices. We also highlight upon graphene's
nonlinear optical response to an applied electric field, and the phenomenon of
saturable absorption. Within the context of logical devices, graphene has no
discernible band-gap. Therefore, generating one will be of utmost importance.
Amongst many others, some existing methods to open this band-gap include
chemical doping, deformation of the honeycomb structure, or the use of carbon
nanotubes (CNTs). We shall also discuss various designs of transistors,
including those which incorporate CNTs, and others which exploit the idea of
quantum tunneling. A key advantage of the CNT transistor is that ballistic
transport occurs throughout the CNT channel, with short channel effects being
minimized. We shall also discuss recent developments of the graphene tunneling
transistor, with emphasis being placed upon its operational mechanism. Finally,
we provide perspective for incorporating graphene within high frequency
devices, which do not require a pre-defined band-gap.Comment: Due to be published in "Current Topics in Applied Spectroscopy and
the Science of Nanomaterials" - Springer (Fall 2014). (17 pages, 19 figures
A mathematical and computational review of Hartree-Fock SCF methods in Quantum Chemistry
We present here a review of the fundamental topics of Hartree-Fock theory in
Quantum Chemistry. From the molecular Hamiltonian, using and discussing the
Born-Oppenheimer approximation, we arrive to the Hartree and Hartree-Fock
equations for the electronic problem. Special emphasis is placed in the most
relevant mathematical aspects of the theoretical derivation of the final
equations, as well as in the results regarding the existence and uniqueness of
their solutions. All Hartree-Fock versions with different spin restrictions are
systematically extracted from the general case, thus providing a unifying
framework. Then, the discretization of the one-electron orbitals space is
reviewed and the Roothaan-Hall formalism introduced. This leads to a exposition
of the basic underlying concepts related to the construction and selection of
Gaussian basis sets, focusing in algorithmic efficiency issues. Finally, we
close the review with a section in which the most relevant modern developments
(specially those related to the design of linear-scaling methods) are commented
and linked to the issues discussed. The whole work is intentionally
introductory and rather self-contained, so that it may be useful for non
experts that aim to use quantum chemical methods in interdisciplinary
applications. Moreover, much material that is found scattered in the literature
has been put together here to facilitate comprehension and to serve as a handy
reference.Comment: 64 pages, 3 figures, tMPH2e.cls style file, doublesp, mathbbol and
subeqn package
The Fungal Cell Wall : Structure, Biosynthesis, and Function
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M. are part of the MRC Centre for Medical Mycology. J.P.L. acknowledges support from ANR, Aviesan, and FRM.Peer reviewedPublisher PD
Internal solitary waves in the Mozambique Channel: Observations and interpretation
This paper presents new results showing that the Sofala shelf in the Mozambique Channel (20°S, 36°E) is a previously unknown “hot spot” for the generation of internal tides and internal waves. We investigate available Envisat advanced synthetic aperture radar imagery of the region, which is capable of showing the surface signatures of the internal waves. This is complemented by modeling of the ray pathways of internal tidal energy propagation, and of the P. G. Baines (1982) barotropic body force, which drives the generation of internal tides near the shelf break. The hot spot region is localized between 20° and 21°S because of the particular nature of the bathymetry there. Farther north and south, the forcing is reduced and insufficient to generate internal solitary waves in the synthetic aperture radar images. The analysis reveals two distinct types of internal wave trains that are observed traveling oceanward away from the shelf break, and we suggest that these result from direct generation at the shelf break and from “local” generation at about 80 km from the shelf break, respectively, because of the surfacing of internal tidal rays at the thermocline. Finally, we have investigated seasonal differences in the wave patterns, which penetrate more extensively into the channel during the southern summer and appear slightly farther to the south during the southern winter. We also conclude that the local generation process is more likely to occur during the winter when the stratification is reduced. <br/
Energy gaps, topological insulator state and zero-field quantum Hall effect in graphene by strain engineering
Among many remarkable qualities of graphene, its electronic properties
attract particular interest due to a massless chiral character of charge
carriers, which leads to such unusual phenomena as metallic conductivity in the
limit of no carriers and the half-integer quantum Hall effect (QHE) observable
even at room temperature [1-3]. Because graphene is only one atom thick, it is
also amenable to external influences including mechanical deformation. The
latter offers a tempting prospect of controlling graphene's properties by
strain and, recently, several reports have examined graphene under uniaxial
deformation [4-8]. Although the strain can induce additional Raman features
[7,8], no significant changes in graphene's band structure have been either
observed or expected for realistic strains of approx. 10% [9-11]. Here we show
that a designed strain aligned along three main crystallographic directions
induces strong gauge fields [12-14] that effectively act as a uniform magnetic
field exceeding 10 T. For a finite doping, the quantizing field results in an
insulating bulk and a pair of countercirculating edge states, similar to the
case of a topological insulator [15-20]. We suggest realistic ways of creating
this quantum state and observing the pseudo-magnetic QHE. We also show that
strained superlattices can be used to open significant energy gaps in
graphene's electronic spectrum
Azimuthal anisotropy and correlations at large transverse momenta in and Au+Au collisions at = 200 GeV
Results on high transverse momentum charged particle emission with respect to
the reaction plane are presented for Au+Au collisions at =
200 GeV. Two- and four-particle correlations results are presented as well as a
comparison of azimuthal correlations in Au+Au collisions to those in at
the same energy. Elliptic anisotropy, , is found to reach its maximum at
GeV/c, then decrease slowly and remain significant up to
-- 10 GeV/c. Stronger suppression is found in the back-to-back
high- particle correlations for particles emitted out-of-plane compared to
those emitted in-plane. The centrality dependence of at intermediate
is compared to simple models based on jet quenching.Comment: 4 figures. Published version as PRL 93, 252301 (2004
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