Are there fetal stem cells in the maternal brain?

GUZEL, Ali irfan/0000-0002-9720-5920; Tunc, Erdal/0000-0003-4964-1004;WOS: 000317029800002PubMed: 25206703Fetal cells can enter maternal blood during pregnancy but whether they can also cross the blood-brain barrier to enter the maternal brain remains poorly understood. Previous results suggest that fetal cells are summoned to repair damage to the mother's brain. If this is confirmed, it would open up new and safer avenues of treatment for brain damage caused by strokes and neural diseases. in this study, we aimed to investigate whether a baby's stem cells can enter the maternal brain during pregnancy. Deceased patients who had at least one male offspring and no history of abortion and blood transfusion were included in this study. DNA was extracted from brain tissue samples of deceased women using standard phenol-chloroform extraction and ethanol precipitation methods. Genomic DNA was screened by quantitative fluorescent-polymerase chain reaction amplification together with short tandem repeat markers specific to the Y chromosome, and 13, 18, 21 and X. Any foreign DNA residues that could be used to interpret the presence of fetal stem cells in the maternal brain were monitored. Results indicated that fetal stem cells can not cross the blood-brain barrier to enter the maternal brain.Research Funds of University of Cukurova, TurkeyCukurova UniversityThe study was supported by Research Funds of University of Cukurova, Turkey

The investigation of the relationship between the factors that prevent university students from attending to the recreational activities and the life satisfaction of the participantsÜniversite öğrencilerinin rekreatif etkinliklere katılımlarına engel teşkil eden faktörler ile katılımcıların yaşam doyumları arasındaki ilişkinin incelenmesi

The aim of the study is to investigate the relationship between the factors that prevent university students from attending to the recreational activities and the life satisfaction of the participants with the demographic variance. In accordance with this purpose, totally 263 students that are 140 (53.2%) “women” and 123 (46.8%) “men” who have been chosen with random sampling method attended to the study voluntarily.In this investigation, “Free Time Obstacles” ,which has been developed by Gürbüz and Karaküçük to determine the factors that might obstruct the attendance of the participants to the recreational activities and evaluates the factors that might prevent the university students from attending to recreational activities, was used. LSS (Life Satisfaction Scale) ,which has been created by Diener and his colleagues (1985) and adapted to Turkish by Yetim(1993), was used to evaluate the life satisfaction of the participants.Percentage (%) and frequency (f) methods were used to determine the distributions personal information of the participants; Shapiro Wilks normality test was used to determine whether data have normal distribution or not and as a result of these, after it is understood that the data are appropriate to the conditions of non-parametric test; Mann- Whitney U and Kruskall Wallis tests were used to determine the significant differences; and Spearman Correlation Test was carried out to determine the relationship between Free Time Obstacles Scale and Life Satisfaction Scale.As a result; it is observed that there is no significant relationship between Free Time Obstacles Scale and Life Satisfaction Scale; there is no significant difference between Life Satisfaction and gender variance considering gender variance; according to the Free Time Obstacles, there is only significant difference at the time sub-dimension; according to the doing sport, there is only significant difference at the Lack of Interest among the Free Time Obstacles; according to the Life Satisfaction, there is significant difference because of the people that don’t participate to the sportive activities. While according to the wealth level, a significant difference was determined at Life Satisfaction level, it is was determined that there is no significant difference at Free Time Obstacles and wealth level. Also, it is determined that there is a significant difference between Life Satisfaction and having difficulty in taking advantage of free time; there is a significant difference between having difficulty in taking advantage of free time and Free Time Obstacles at facility-service and time sub-dimension.Extended English abstract is in the end of PDF (TURKISH) file. ÖzetÇalışmanın amacı üniversite öğrencilerin rekreatif etkinliklere katılımlarına engel teşkil eden faktörler ile katılımcıların yaşam doyumları arasındaki ilişkinin demografik değişkenler ile birlikte incelenmesidir. Bu amaç doğrultusunda tesadüfi örnekleme yöntemiyle seçilmiş olan 140 (%53.2) “Kadın” ve 123 (%46.8) “Erkek” toplam 263 üniversite öğrencisi çalışmaya gönüllü olarak katılmıştır.Araştırmada, katılımcıların rekreasyonel faaliyetlere katılımlarına engel teşkil edebilecek faktörlerin belirlenmesi için Gürbüz ve Karaküçük tarafından geliştirilen üniversite öğrencilerinin rekreasyonel etkinliklerine katılmalarına engel teşkil edebilecek unsurları değerlendiren “Boş Zaman Engelleri” kullanılmıştır. Katılımcıların yaşam doyumlarını ölçmek amacıyla ise Diener ve arkadaşları (1985) tarafından geliştirilen ve Yetim (1993) tarafından Türkçe’ye uyarlanan YDÖ (Yaşam Doyumu Ölçeği) kullanılmıştır.Katılımcıların kişisel bilgilerinin dağılımlarının belirlenmesi için yüzde (%) ve frekans (f) yöntemleri; verilerin normal bir dağılıma sahip olup olmadığının belirlenmesi için Shapiro Wilks normallik testi uygulanmış ve bunun neticesinde verilerin non parametrik test koşullarına uygun olduğunun anlaşılmasından sonra anlamlı farklılıkların belirlenmesi için Mann-Whitney U ve Kruskall Wallis testleri, Boş Zaman Engelleri Ölçeği ile Yaşam Doyumu Ölçeği arasındaki ilişkinin belirlenmesi için ise Spearman Korelasyon testi uygulanmıştır.Sonuç olarak; boş zaman engelleri ile yaşam doyumu arasında, cinsiyet değişkeni açısından bakıldığında yaşam doyumu ile cinsiyet değişkeni arasında anlamlı bir farklılık olmadığı tespit edilmiştir. Boş zaman engelleri açısından ise sadece zaman alt boyutunda anlamlı bir farklılık olduğu, spor yapma durumuna göre boş zaman engelleri arasında da sadece ilgi eksikliği boyutunda anlamlı bir farklılık olduğu saptanmış, yaşam doyumuna göre incelendiğinde ise sportif etkinliklere katılmayan kişilerden kaynaklı anlamlı bir farklılığın olduğu ortaya çıkmıştır. Refah düzeyi değişkenine göre incelendiğinde yaşam doyumu düzeyinde anlamlı bir farklılık saptanmasına karşın boş zaman engelleri açısından refah düzeyinde ise anlamlı bir farklılık olmadığı tespit edilmiştir. Ayrıca yaşam doyumu ile boş zamanları değerlendirme güçlüğü çekmek arasında anlamlı bir farklılık olduğu, boş zaman değerlendirme güçlüğü çekmek ile boş zaman engelleri arasında ise tesis-hizmet ve zaman alt boyutlarında anlamlı bir farklılık olduğu tespit edilmiştir

The initial part of polymorphic ventricular tachycardia as a clue for the sustainability of tachycardia and ablation success: A varying degree of purkinje–Myocardial complicity?

The cardiac Purkinje system is capable of very rapid burst activity suggestive of its potential role in being a driver of polymorphic ventricular tachycardia (VT) (PMVT) or ventricular fibrillation (VF). It plays a pivotal role, however, not only in the triggering of but also the perpetuation of ventricular arrhythmias. A varying degree of Purkinje–myocardial complicity has been blamed in determining not only the sustained or non-sustained nature of PMVT but also the pleomorphism of the non-sustained runs. The initial part of PMVT before cascading to the whole ventricle to establish disorganized VF can give important clues for ablation of PMVT and VF. We present a case of an electrical storm after acute myocardial infarction that was successfully ablated after identifying Purkinje potentials that triggered polymorphic, monomorphic, and pleiomorphic VTs and VF

Minimally invasive repair of pectus excavatum (MIRPE) in adults: is it a proper choice?

Introduction : The Nuss procedure is suitable for prepubertal and early pubertal patients but can also be used in adult patients. Aim : To determine whether the minimally invasive technique (MIRPE) can also be performed successfully in adults. Material and methods : Between July 2006 and January 2016, 836 patients (744 male, 92 female) underwent correction of pectus excavatum with the MIRPE technique at our institution. The mean age was 16.8 years (2–45 years). There were 236 adult patients (28.2%) (> 18 years) – 20 female, 216 male. The mean age among the adult patients was 23.2 years (18–45 years). The recorded data included length of hospital stay, postoperative complications, number of bars used, duration of the surgical procedure and signs of pneumothorax on the postoperative chest X-ray. Results: MIRPE was performed in 236 adult patients. The average operative time was 44.4 min (25–90 min). The median postoperative stay was 4.92 ±2.81 days (3–21 days) in adults and 4.64 ±1.58 (2–13) in younger patients. The difference was not statistically significant (p = 0.637). Two or more bars were used in 36 (15.8%) adult patients and in 44 (7.5%) younger patients. The difference was not statistically significant either (p = 0.068). Regarding the overall complications, complication rates among the adult patients and younger patients were 26.2% and 11.8% respectively. The difference was statistically significant (p = 0.007). Conclusions : MIRPE is a feasible procedure that produces good long-term results in the treatment of pectus excavatum in adults

Effects of Coronary Artery Bypass Grafting Surgery on Olfactory and Taste Functions

Conclusion: Our study demonstrated that olfactory function was impaired in patients, who underwent on-pump CABG in the postoperative period, and significant impairment in taste function was present in neither off-pump nor on-pump CABG patients. However, the results of our study should be supported by more comprehensive, prospective, randomized controlled trials with more extensive patient series and by further tests

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Konakçı çeşitinin Anopheles sacharovi Favre' nin yumurta verimi ve ömür uzunluğuna etkisi

TEZ368Tez (Yüksek Lisans) -- Çukurova Üniversitesi, Adana, 1987.Kaynakça (s.50-55) var.iv, 56 s. ; 30 cm.

Sıtma vektörü [Anopheles sacharovi] favre'de konak tercihi

TEZ885Tez (Doktora) -- Çukurova Üniversitesi, Adana, 1991.Kaynakça (s. 38-42) var.rnk. res. ; 30 cm.