Selective CO₂ capture in metal-organic frameworks with azine-functionalized pores generated by mechanosynthesis

Two new three-dimensional porous Zn(II)-based metal-organic frameworks, containing azine-functionalized pores, have been readily and quickly isolated via mechanosynthesis, by using a nonlinear dicarboxylate and linear N-donor ligands. The use of nonfunctionalized and methyl-functionalized N-donor ligands has led to the formation of frameworks with different topologies and metal-ligand connectivities and therefore different pore sizes and accessible volumes. Despite this, both metal-organic frameworks (MOFs) possess comparable BET surface areas and CO₂ uptakes at 273 and 298 K at 1 bar. The network with narrow and interconnected pores in three dimensions shows greater affinity for CO compared to the network with one-dimensional and relatively large pores-attributable to the more effective interactions with the azine groups

Improving the multiobjective evolutionary algorithm based on decomposition with new penalty schemes

It has been increasingly reported that the multiobjective optimization evolutionary algorithm based on decomposition (MOEA/D) is promising for handling multiobjective optimization problems (MOPs). MOEA/D employs scalarizing functions to convert an MOP into a number of single-objective subproblems. Among them, penalty boundary intersection (PBI) is one of the most popular decomposition approaches and has been widely adopted for dealing with MOPs. However, the original PBI uses a constant penalty value for all subproblems and has difficulties in achieving a good distribution and coverage of the Pareto front for some problems. In this paper, we investigate the influence of the penalty factor on PBI, and suggest two new penalty schemes, i.e., adaptive penalty scheme and subproblem-based penalty scheme (SPS), to enhance the spread of Pareto-optimal solutions. The new penalty schemes are examined on several complex MOPs, showing that PBI with the use of them is able to provide a better approximation of the Pareto front than the original one. The SPS is further integrated into two recently developed MOEA/D variants to help balance the population diversity and convergence. Experimental results show that it can significantly enhance the algorithm�s performance. © 2016, Springer-Verlag Berlin Heidelberg

Postoperative intravenously administered iron sucrose versus postoperative orally administered iron to treat post-bariatric abdominoplasty anaemia (ISAPA): the study protocol for a randomised controlled trial

BACKGROUND: Anaemia and iron deficiency are common complications following post-bariatric abdominoplasty. Given the low oral absorbability of iron resulting from bariatric surgery, it has been hypothesised that postoperative intravenously administered iron supplementation could be used to treat anaemia and to prevent the development of iron deficiency in these patients. METHODS/DESIGN: In this multicentre open-label randomised clinical trial, 56 adult women undergoing post-bariatric anchor-line abdominoplasty will be allocated at a ratio of 1:1 for postoperative supplementation with two intravenously administered applications of 200 mg of iron saccharate or postoperative supplementation with 100 mg of iron polymaltose complex administered orally, twice a day for 8 weeks. The primary outcome is the difference in mean haemoglobin levels between the two groups at eight postoperative weeks. Secondary outcomes evaluated at one, four and eight postoperative weeks include iron profile, reticulocyte count, overall quality of life measured using the Short-Form 36 Health Survey (SF-36) questionnaire, fatigue measured using the Functional Assessment of Chronic Illness Therapy – Fatigue (FACIT-F), adverse effects and postoperative complications. DISCUSSION: This randomised clinical trial aims to evaluate the haematopoietic effectiveness of intravenously administered iron supplementation in patients undergoing post-bariatric abdominoplasty. A more effective recovery of haemoglobin levels could help improve the patients’ quality of life and could provide an improved haematological status in preparation for the subsequent and frequent plastic surgeries these patients undergo. TRIAL REGISTRATION: Clinicaltrials.gov Identifier: NCT01857011 (8 May 2013), Universal Trial Number U111-1169-6223, Brazilian Clinical Trials Registry (REBEC): RBR-2JGRKQ

Current trend in synthesis, Post-Synthetic modifications and biological applications of Nanometal-Organic frameworks (NMOFs)

Since the early reports of MOFs and their interesting properties, research involving these materials has grown wide in scope and applications. Various synthetic approaches have ensued in view of obtaining materials with optimised properties, the extensive scope of application spanning from energy, gas sorption, catalysis biological applications has meant exponentially evolved over the years. The far‐reaching synthetic and PSM approaches and porosity control possibilities have continued to serve as a motivation for research on these materials. With respect to the biological applications, MOFs have shown promise as good candidates in applications involving drug delivery, BioMOFs, sensing, imaging amongst others. Despite being a while away from successful entry into the market, observed results in sensing, drug delivery, and imaging put these materials on the spot light as candidates poised to usher in a revolution in biology. In this regard, this review article focuses current approaches in synthesis, post functionalization and biological applications of these materials with particular attention on drug delivery, imaging, sensing and BioMOFs

2013 WSES guidelines for management of intra-abdominal infections

Peer reviewe

WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis

Acute appendicitis (AA) is among the most common cause of acute abdominal pain. Diagnosis of AA is challenging; a variable combination of clinical signs and symptoms has been used together with laboratory findings in several scoring systems proposed for suggesting the probability of AA and the possible subsequent management pathway. The role of imaging in the diagnosis of AA is still debated, with variable use of US, CT and MRI in different settings worldwide. Up to date, comprehensive clinical guidelines for diagnosis and management of AA have never been issued. In July 2015, during the 3rd World Congress of the WSES, held in Jerusalem (Israel), a panel of experts including an Organizational Committee and Scientific Committee and Scientific Secretariat, participated to a Consensus Conference where eight panelists presented a number of statements developed for each of the eight main questions about diagnosis and management of AA. The statements were then voted, eventually modified and finally approved by the participants to The Consensus Conference and lately by the board of co-authors. The current paper is reporting the definitive Guidelines Statements on each of the following topics: 1) Diagnostic efficiency of clinical scoring systems, 2) Role of Imaging, 3) Non-operative treatment for uncomplicated appendicitis, 4) Timing of appendectomy and in-hospital delay, 5) Surgical treatment 6) Scoring systems for intra-operative grading of appendicitis and their clinical usefulness 7) Non-surgical treatment for complicated appendicitis: abscess or phlegmon 8) Pre-operative and post-operative antibiotics.Peer reviewe

Regeneration and reconstruction of metal-organic frameworks: Opportunities for industrial usage

Over the past two decades, metal–organic frameworks (MOFs) with special and designable structures, adjustable cavity size, and high surface area have attracted special attention for their applications as adsorbents, catalysts and photocatalysts, among other uses. However, due to production costs and performance, large scale and industrial usage of such materials is still limited. Particularly for the use of MOFs as adsorbents, it is essential to examine appropriate regeneration methods in order to be reusable. In other applications, particularly in catalysis, reconstruction of MOFs is necessary in order to regain the initial activity of fresh materials and facilitate their application at industrial scale. The goal of this review is to provide a comprehensive assessment of the regeneration procedures and reconstruction techniques for MOF adsorbents based on the existing data. This discussion is further extended to describe the impact of temperature, pressure, and moisture on the interaction between adsorbent/adsorbate molecules, and the stability and capacity of sorbents after regeneration. This review will help readers to gain insights into the desorption process in MOF as adsorbents under different regeneration conditions