59 research outputs found
Construction of Red Fox Chromosomal Fragments from the Short-Read Genome Assembly
- Author
- Publication venue
- Publication date
- 01/01/2018
- Field of study
The genome of a red fox (Vulpes vulpes) was recently sequenced and assembled using next-generation sequencing (NGS). The assembly is of high quality, with 94X coverage and a scaffold N50 of 11.8 Mbp, but is split into 676,878 scaffolds, some of which are likely to contain assembly errors. Fragmentation and misassembly hinder accurate gene prediction and downstream analysis such as the identification of loci under selection. Therefore, assembly of the genome into chromosome-scale fragments was an important step towards developing this genomic model. Scaffolds from the assembly were aligned to the dog reference genome and compared to the alignment of an outgroup genome (cat) against the dog to identify syntenic sequences among species. The program Reference-Assisted Chromosome Assembly (RACA) then integrated the comparative alignment with the mapping of the raw sequencing reads generated during assembly against the fox scaffolds. The 128 sequence fragments RACA assembled were compared to the fox meiotic linkage map to guide the construction of 40 chromosomal fragments. This computational approach to assembly was facilitated by prior research in comparative mammalian genomics, and the continued improvement of the red fox genome can in turn offer insight into canid and carnivore chromosome evolution. This assembly is also necessary for advancing genetic research in foxes and other canids
Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine
- Author
- Amaral Michelle
- Amendola Laura
- Amendola Laura M.
- Appelbaum Paul S.
- Appelbaum Paul S.
- Aronson Samuel J.
- Arora Shubhangi
- Azzariti Danielle R.
- Barsh Greg S.
- Bebin E.M.
- Berg Jonathan S.
- Bernhardt Barbara A.
- Biesecker Barbara B.
- Biesecker Leslie G.
- Biesecker Leslie G.
- Biswas Sawona
- Biswas Sawona
- Blout Carrie L.
- Blout Carrie L.
- Bowling Kevin M.
- Bowling Kevin M.
- Breitkopf Carmen Radecki
- Brothers Kyle B.
- Brothers Kyle B.
- Brown Brian L.
- Burke Wylie
- Burt Amber A.
- Byers Peter H.
- Caga-anan Charlisse F.
- Caga-anan Charlisse F.
- Calikoglu Muge G.
- Carlson Sara J.
- Chahin Nizar
- Chinnaiyan Arul M.
- Chinnaiyan Arul M.
- Christensen Kurt D.
- Chung Wendy
- Chung Wendy K.
- Cirino Allison L.
- Clayton Ellen
- Clayton Ellen W.
- Conlin Laura K.
- Cooper Gregory M.
- Cooper Greg M.
- Crosslin David R.
- Davis James V.
- Davis Kelly
- Deardorff Matthew A.
- Devkota Batsal
- De Vries Raymond
- Diamond Pamela
- Dorschner Michael O.
- Dugan Noreen P.
- Dukhovny Dmitry
- Dulik Matthew C.
- East Kelly
- East Kelly M.
- Evans Barbara
- Evans James P.
- Evans James P.
- Everett Jessica
- Exe Nicole
- Fan Zheng
- Feuerman Lindsay Z.
- Filipski Kelly
- Finnila Candice R.
- Fishler Kristen
- Fullerton Stephanie M.
- Fullerton Stephanie M.
- Garraway Levi A.
- Garrett Jeremy R.
- Ghrundmeier Bob
- Giles Karen
- Gilmore Marian J.
- Girnary Zahra S.
- Goddard Katrina
- Goddard Katrina A.B.
- Gonsalves Steven
- Gordon Adam S.
- Gornick Michele C.
- Grady William M.
- Gray David E.
- Gray Stacy W.
- Gray Stacy W.
- Green Robert
- Green Robert C.
- Greenwood Robert S.
- Gutierrez Amanda M.
- Han Paul
- Hart Ragan
- Heagerty Patrick
- Henderson Gail E.
- Henderson Gail E.
- Hensman Naomi
- Hiatt Susan M.
- Himes Patricia
- Hindorff Lucia A.
- Hindorff Lucia A.
- Hisama Fuki M.
- Ho Carolyn Y.
- Hoffman-Andrews Lily B.
- Holm Ingrid A.
- Holm Ingrid A.
- Hong Celine
- Horike-Pyne Martha J.
- Hull Sara
- Hutter Carolyn M.
- Hutter Carolyn M.
- Jamal Seema
- Janne Pasi A.
- Jarvik Gail P.
- Jarvik Gail P.
- Jensen Brian C.
- Joffe Steve
- Joffe Steven
- Johnston Jennifer
- Karavite Dean
- Kauffman Tia L.
- Kaufman Dave
- Kaufman David
- Kelley Whitley
- Kim Jerry H.
- Kirby Christine
- Klein William
- Knoppers Bartha
- Knoppers Bartha M.
- Koenig Barbara A.
- Koenig Barbara A.
- Kong Sek Won
- Krantz Ian
- Krantz Ian D.
- Krier Joel B.
- Lamb Neil E.
- Lambert Michele P.
- Le Lan Q.
- Lebo Matthew S.
- Lee Alexander
- Lee Kaitlyn B.
- Lennon Niall
- Leo Michael C.
- Leppig Kathleen A.
- Lewis Katie
- Lewis Michelle
- Lewis Michelle Huckaby
- Lindeman Neal I.
- Lockhart Nicole
- Lonigro Bob
- Lose Edward J.
- Lupo Philip J.
- Lynch Frances
- Machini Kalotina
- MacRae Calum
- Manolio Teri A.
- Manolio Teri A.
- Marchuk Daniel S.
- Martinez Josue N.
- Masino Aaron
- McCullough Laurence
- McCullough Laurence
- McEwen Jean
- McEwen Jean
- McGuire Amy
- McGuire Amy
- McLaughlin Heather M.
- McMullen Carmit
- Mieczkowski Piotr A.
- Miller Jeff
- Miller Victoria A.
- Mody Rajen
- Mooney Sean D.
- Moore Elizabeth G.
- Morris Elissa
- Murray Michael
- Muzny Donna
- Muzny Donna
- Myers Richard M.
- Myers Richard M.
- Ng David
- Nickerson Deborah A.
- Nickerson Deborah A.
- Oliver Nelly M.
- Ou Jeffrey
- Ou Jeffrey
- Parsons Donald W.
- Parsons Will
- Patrick Donald L.
- Pennington Jeffrey
- Perry Denise L.
- Petersen Gloria
- Petersen Gloria M.
- Plon Sharon
- Plon Sharon E.
- Porter Katie
- Powell Bradford C.
- Punj Sumit
- Raesz-Martinez Robin A.
- Raskind Wendy H.
- Rehm Heidi L.
- Rehm Heidi L.
- Reigar Dean A.
- Reiss Jacob A.
- Rich Carla A.
- Richards Carolyn Sue
- Rini Christine
- Rivera-Munoz Edgar A.
- Roberts J. Scott
- Roberts Scott
- Robertson Peggy D.
- Robinson Dan
- Robinson Dan
- Robinson Jill O.
- Robinson Marguerite E.
- Roche Myra I.
- Rodriguez Laura Lyman
- Romasko Edward J.
- Rosenthal Elisabeth A.
- Salama Joseph
- Salama Joseph S.
- Scarano Maria I.
- Schneider Jennifer
- Scollon Sarah
- Scollon Sarah
- Seidman Christine E.
- Seifert Bryce A.
- Sharp Richard R.
- Sharp Richard R.
- Shirts Brian
- Shirts Brian H.
- Sholl Lynette M.
- Siddiqui Javed
- Silverman Elian
- Simmons Shirley
- Simons Janae V.
- Skinner Debra
- Spinner Nancy B.
- Spinner Nancy B.
- Stoffel Elena
- Strande Natasha T.
- Sunyaev Shamil
- Sybert Virginia P.
- Taber Jennifer
- Tabor Holly K.
- Tabor Holly K.
- Tarczy-Hornoch Peter
- Tarczy-Hornoch Peter
- Taylor Deanne M.
- Tilley Christian R.
- Tomlinson Ashley
- Trinidad Susan
- Tsai Ellen
- Ubel Peter
- Van Allen Eliezer M.
- Vassy Jason L.
- Vats Pankaj
- Veenstra David L.
- Veenstra David L.
- Vetter Victoria L.
- Vries Raymond D.
- Wagle Nikhil
- Wagle Nikhil
- Walser Sarah A.
- Walsh Rebecca C.
- Weck Karen
- Weck Karen
- Werner-Lin Allison
- Whittle Jana
- Wilfond Ben
- Wilfond Benjamin S.
- Wilhelmsen Kirk
- Wilhelmsen Kirk C.
- Wolf Susan M.
- Wolf Susan M.
- Wynn Julia
- Wynn Julia
- Yang Yaping
- Young Carol
- Yu Joon-Ho
- Yu Joon-Ho
- Zikmund-Fisher Brian J.
- Publication venue
- Publication date
- 01/01/2016
- Field of study
Despite rapid technical progress and demonstrable effectiveness for some types of diagnosis and therapy, much remains to be learned about clinical genome and exome sequencing (CGES) and its role within the practice of medicine. The Clinical Sequencing Exploratory Research (CSER) consortium includes 18 extramural research projects, one National Human Genome Research Institute (NHGRI) intramural project, and a coordinating center funded by the NHGRI and National Cancer Institute. The consortium is exploring analytic and clinical validity and utility, as well as the ethical, legal, and social implications of sequencing via multidisciplinary approaches; it has thus far recruited 5,577 participants across a spectrum of symptomatic and healthy children and adults by utilizing both germline and cancer sequencing. The CSER consortium is analyzing data and creating publically available procedures and tools related to participant preferences and consent, variant classification, disclosure and management of primary and secondary findings, health outcomes, and integration with electronic health records. Future research directions will refine measures of clinical utility of CGES in both germline and somatic testing, evaluate the use of CGES for screening in healthy individuals, explore the penetrance of pathogenic variants through extensive phenotyping, reduce discordances in public databases of genes and variants, examine social and ethnic disparities in the provision of genomics services, explore regulatory issues, and estimate the value and downstream costs of sequencing. The CSER consortium has established a shared community of research sites by using diverse approaches to pursue the evidence-based development of best practices in genomic medicine
Identification of common genetic risk variants for autism spectrum disorder
- Author
- Abdellaoui Abdel
- Adams Mark J.
- Agee Michelle
- Agerbo Esben
- Air Tracy M.
- Alipanahi Babak
- Als Thomas D.
- Andlauer Till F. M.
- Andreassen Ole A.
- Anney Richard
- Arolt Volker
- Auton Adam
- Awashti Swapnil
- Bacanu Silviu-Alin
- Baekvad-Hansen Marie
- Baune Bernhard T.
- Beekman Aartjan T. F.
- Bell Robert K.
- Belliveau Rich
- Berger Klaus
- Bettella Francesco
- Bigdeli Tim B.
- Binder Elisabeth B.
- Blackwood Douglas H. R.
- Boomsma Dorret
- Borglum Anders D.
- Breen Gerome
- Bryc Katarzyna
- Bryois Julien
- Buttenschon Henriette N.
- Buxbaum Joseph D.
- Bybjerg-Grauholm Jonas
- Byrne Enda M.
- Cai Na
- Castelao Enrique
- Cerrato Felecia
- Chambert Kimberly
- Christensen Jane H.
- Churchhouse Claire
- Cichon Sven
- Clarke Toni-Kim
- Coleman Jonathan R.
- Colodro-Conde Lucia
- Couvy-Duchesne Baptiste
- Craddock Nick
- Crawford Gregory E.
- Daly Mark J.
- Dannlowski Udo
- Davies Gail
- de Geus E. J. C.
- De Rubeis Silvia
- Deary Ian J.
- Degenhardt Franziska
- Dellenvall Karin
- Demontis Ditte
- DePaulo J. Raymond
- Derks Eske M.
- Devlin Bernie
- Direk Nese
- Djurovic Srdjan
- Dolan Conor
- Domenici Enrico
- Domschke Katharina
- dPoterba Timothy
- Dumont Ashley L.
- Dunn Erin C.
- Eley Thalia C.
- Elson Sarah L.
- Escott-Price Valentina
- Esko Tonu
- Finucane Hilary K.
- Fontanillas Pierre
- Forstner Andreas J.
- Frank Josef
- Furlotte Nicholas A.
- Gaspar Helena A.
- Geschwind Daniel H.
- Gill Michael
- Goes Fernando S.
- Goldstein Jacqueline
- Gordon Scott D.
- Grabe Hans J.
- Grove Jakob
- Hall Lynsey S.
- Hamilton Steven P.
- Hansen Christine S.
- Hansen Thomas F.
- Hauberg Mads Engel
- Hayward Caroline
- Heath Andrew C.
- Herms Stefan
- Hickie Ian B.
- Hoffmann Per
- Hollegaard Mads
- Homuth Georg
- Hope Sigrun
- Horn Carsten
- Hottenga Jouke-Jan
- Hougaard David M.
- Howrigan Daniel P.
- Hromatka Bethann S.
- Huang Hailiang
- Huber Karen E.
- Hultman Christina M.
- Ising Marcus
- Jansen Rick
- Jörgenson Eric
- Kendler Kenneth S.
- Kiadeh Farnush Farhadi Hassan
- Klei Lambertus
- Kleinman Aaron
- Kloiber Stefan
- Knowles James A.
- Kohane Isaac S.
- Kraft Julia
- Kretzschmar Warren W.
- Krogh Jesper
- Kutalik Zoltan
- Levinson Douglas F.
- Lewis Cathryn M.
- Lewis Glyn
- Li Qingqin S.
- Li Yihan
- Lind Penelope A.
- Litterman Nadia K.
- Lucae Susanne
- MacIntyre Donald J.
- MacKinnon Dean F.
- Madden Pamela A. F.
- Magnusson Patrik K.
- Maier Robert M.
- Maier Wolfgang
- Maller Julian
- Marchini Jonathan
- Martin Alicia R.
- Martin Joanna
- Martin Nicholas G.
- Mattheisen Manuel
- Mbarek Hamdi
- McGrath Patrick
- McGuffin Peter
- McIntosh Andrew M.
- McIntyre Matthew H.
- Medland Sarah E.
- Mehta Divya
- Metspalu Andres
- Middeldorp Christel M.
- Mihailov Evelin
- Milaneschi Yuri
- Milani Lili
- Mirza Saira Saeed
- Mondimore Francis M.
- Montgomery Grant W.
- Moran Jennifer L.
- Mors Ole
- Mortensen Preben Bo
- Mostafavi Sara
- Mountain Joanna L.
- Mullins Niamh
- Müller-Myhsok Bertram
- Naerland Terje
- Nauck Matthias
- Neale Benjamin M.
- Ng Bernard
- Nivard Michel G.
- Noblin Elizabeth S.
- Noethen Markus M.
- Nordentoft Merete
- Northover Carrie A. M.
- Nyegaard Mette
- Nyholt Dale R.
- O'Donovan Michael C.
- O'Reilly Paul F.
- Oskarsson Hogni
- Owen Michael J.
- Paciga Sara A.
- Painter Jodie N.
- Pallesen Jonatan
- Palmer Duncan S.
- Palotie Aarno
- Pedersen Carsten Bocker
- Pedersen Marianne Giortz
- Pedersen Nancy L.
- Penninx Brenda W. J. H.
- Perlis Roy H.
- Peterson Roseann E.
- Pettersson Erik
- Peyrot Wouter J.
- Pistis Giorgio
- Pitts Steven J.
- Porteous David J.
- Posthuma Danielle
- Potash James B.
- Poulsen Jesper Buchhave
- Preisig Martin
- Quiroz Jörge A.
- Qvist Per
- Rehnstrom Karola
- Reichenberg Abraham
- Reichert Jennifer
- Rice John P.
- Rietschel Marcella
- Riley Brien P.
- Ripke Stephan
- Rivera Margarita
- Robinson Elise B.
- Roeder Kathryn
- Roussos Panos
- Saemundsen Evald
- Sandin Sven
- Sathirapongsasuti J. Fah
- Satterstrom F. Kyle
- Sazonova Olga
- Schoevers Robert
- Schulte Eva C.
- Schulze Thomas G.
- Schäfer Catherine
- Shelton Janie F.
- Shen Ling
- Shi Jianxin
- Shringarpure Suyash
- Shyn Stanley
- Sigurdsson Engilbert
- Sinnamon Grant C. B.
- Smit Johannes H.
- Smith Daniel J.
- Smith George Davey
- Smoller Jordan W.
- St Pourcain Beate
- Stefansson Hreinn
- Stefansson Kari
- Steinberg Stacy
- Stevens Christine R.
- Streit Fabian
- Strohmaier Jana
- Sullivan Patrick F.
- Tansey Katherine E.
- Teismann Henning
- Teumer Alexander
- Thompson Wesley
- Thomson Pippa A.
- Thorgeirsson Thorgeir E.
- Tiemeier Henning
- Traylor Matthew
- Treutlein Jens
- Trubetskoy Vassily
- Trzaskowski Maciej
- Tung Joyce Y.
- Turley Patrick
- Uher Rudolf
- Uitterlinden Andr G.
- Umbricht Daniel
- Vacic Vladimir
- Van Der Auwera Sandra
- van Hemert Albert M.
- Viktorin Alexander
- Visscher Peter M.
- Voelzke Henry
- Walters G. Bragi
- Walters Raymond K.
- Wang Yunpeng
- Webb Bradley T.
- Weinsheimer Shantel Marie
- Weissman Myrna M.
- Wellmann Jürgen
- Werge Thomas
- Willemsen Gonneke
- Wilson Catherine H.
- Witt Stephanie H.
- Won Hyejung
- Wray Naomi R.
- Wu Yang
- Xi Hualin S.
- Xu Xinyi
- Yang Jian
- Zhang Futao
- Publication venue
- Ludwig-Maximilians-Universität München
- Publication date
- 01/01/2019
- Field of study
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants contribute substantially to ASD susceptibility, but to date no individual variants have been robustly associated with ASD. With a marked sample-size increase from a unique Danish population resource, we report a genome-wide association meta-analysis of 18,381 individuals with ASD and 27,969 controls that identified five genome-wide-significant loci. Leveraging GWAS results from three phenotypes with significantly overlapping genetic architectures (schizophrenia, major depression, and educational attainment), we identified seven additional loci shared with other traits at equally strict significance levels. Dissecting the polygenic architecture, we found both quantitative and qualitative polygenic heterogeneity across ASD subtypes. These results highlight biological insights, particularly relating to neuronal function and corticogenesis, and establish that GWAS performed at scale will be much more productive in the near term in ASD
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
- Author
- Abdellaoui Abdel
- Abramova Liliya
- Adams Mark
- Adams Mark J.
- Adan Roger A. H.
- Adolfsson Rolf
- Adolfsson Rolf
- Adorjan Kristina
- Agartz Ingrid
- Agartz Ingrid
- Agerbo Esben
- Agerbo Esben
- Agerbo Esben
- Aguayo Samuel
- Ahuja Sunil
- Air Tracy M.
- Air Tracy M.
- Al Eissa Mariam
- Albani Diego
- Alda Martin
- Alda Martin
- Alfredsson Lars
- Alfredsson Lars
- Alfredsson Lars
- Alliey-Rodriguez Ney
- Als Thomas D.
- Andlauer Till F. M.
- Ando Tetsuya
- Andreassen Ole A.
- Andreassen Ole A.
- Andreassen Ole A.
- Anjorin Adebayo
- Anjorin Adebayo
- Antilla Verneri
- Antoniou Anastasia
- Appadurai Vivek
- Argyres Dean P.
- Arolt Volker
- Artigas Maria Soler
- Aschauer Harald
- Ashley-Koch Allison E.
- Aslan Mihaela
- Awasthi Swapnil
- Awasthi Swapnil
- Awasthi Swapnil
- Azevedo M. Helena
- Babadjanova Gulja
- Bacanu Silviu-Alin
- Backlund Lena
- Baek Ji Hyun
- Baker Jessica H.
- Ballas Zuhair
- Bass Nicholas
- Bass Nicholas
- Bau Claiton H. D.
- Bauer Michael
- Baune Bernhard T.
- Baune Bernhard T.
- Baune Bernhard T.
- Beckham Jean
- Beckham Jean
- Beckham Jean C.
- Beekman Aartjan T. F.
- Beins Eva C.
- Bellivier Frank
- Bellivier Frank
- Bencko Vladimir
- Bengesser Susanne
- Bergen Andrew W.
- Bergen Andrew W.
- Bergen Sarah E.
- Berger Klaus
- Berger Klaus
- Berrettini Wade H.
- Berrettini Wade H.
- Berrettini Wade H.
- Bhushan Sujata
- Biernacka Joanna M.
- Biernacka Joanna M.
- Bigdeli Tim B.
- Bigdeli Tim B.
- Bigdeli Tim B.
- Binder Elisabeth B.
- Binder Elisabeth B.
- Birgegård Andreas
- Birner Armin
- Blackwood Douglas H. R.
- Boden Joseph M.
- Boehm Ilka
- Boehnke Michael
- Boehnke Michael
- Bohus Martin
- Bohus Martin
- Boks Marco P.
- Boks Marco P.
- Boni Claudette
- Boomsma Dorret I.
- Bosch Rosa
- Bosch Rosa
- Boyko Edward
- Braff David L.
- Brandt Harry
- Brandt Harry
- Breeling James
- Breen Gerome
- Breen Gerome
- Breen Gerome
- Breen Gerome
- Brewer Jessica V.
- Brophy Mary T.
- Brum Murielle
- Brumpton Ben M.
- Brunkhorst-Kanaan Nathalie
- Bryant Richard
- Bryois Julien
- Bryois Julien
- Bryois Julien
- Budde Monika
- Budde Monika
- Buehren Katharina
- Bulik Cynthia M.
- Bulik Cynthia M.
- Burghardt Roland
- Buttenschøn Henriette N.
- Bybjerg-Grauholm Jonas
- Bybjerg-Grauholm Jonas
- Byerley William
- Byrne Enda M.
- Byrne Enda M.
- Bækvad-Hansen Marie
- Bækvad-Hansen Marie
- Bøen Erlend
- Børglum Anders D.
- Børglum Anders D.
- Børglum Anders D.
- Børte Sigrid
- Cahn Wiepke
- Cai Na
- Cairns Murray
- Campos Adrian I.
- Carlberg Laura
- Carr Vaughan J.
- Carter Bruce W.
- Casas Miguel
- Casas Miquel
- Cassina Matteo
- Castelao Enrique
- Castelao Enrique
- Catts Stanley
- Cervantes Pablo
- Cervilla Jorge A.
- Chang Kyong-Mi
- Chang Xiao
- Charney Alexander W.
- Chaumette Boris
- Chen Hsi-Chung
- Chen Wei J.
- Cho Kelly
- Cho Kelly
- Christensen Jane Hvarregaard
- Cichon Sven
- Cichon Sven
- Cichon Sven
- Cichon Sven
- Clarke Toni-Kim
- Clarke Toni-Kim
- Clementi Maurizio
- Cohen David
- Coleman Jonathan R. I.
- Coleman Jonathan R. I.
- Coleman Jonathan R. I.
- Coleman Jonathan R. I.
- Colodro-Conde Lucía
- Cone Roger D.
- Connor Todd
- Constans Joseph
- Coombes Brandon
- Coon Hilary
- Corvin Aiden
- Corvin Aiden
- Courtet Philippe
- Couvy-Duchesne Baptiste
- Craddock Nicholas
- Craddock Nicholas
- Craddock Nick
- Craig David
- Crawford Gregory E.
- Crawford Steven
- Crawford Steven
- Crivelli Silvia
- Crow Scott
- Crow Scott
- Crowley James J.
- Cruceanu Cristiana
- Cuellar-Barboza Alfredo
- Cunningham Julie
- Curtis David
- Czerski Piotr M.
- Dahmen Norbert
- Dale Anders M.
- Dalkner Nina
- Danner Unna N.
- Dannlowski Udo
- Dannlowski Udo
- David Friederike S.
- Davies Gail
- Davis Oliver S. P.
- de Geus E. J. C.
- de Zwaan Martina
- Dedoussis George
- Degenhardt Franziska
- Degenhardt Franziska
- Degenhardt Franziska
- Degortes Daniela
- Dellitalia Louis
- Demontis Ditte
- Dennis Michelle F.
- Depaulo J. Raymond
- DePaulo J. Raymond
- der Auwera Sandra Van
- Derks Eske M.
- DeSocio Janiece E.
- Di Florio Arianna
- DiBlasi Emily
- Dick Danielle M.
- Dietl Lydie
- Dikeos Dimitris
- Dikeos Dimitris
- Dina Christian
- Direk Nese
- Djurovic Srdjan
- Djurovic Srdjan
- Dmitrzak-Weglarz Monika
- Do Nhan
- Dobbyn Amanda L.
- Docherty Anna R.
- Dolan Conor V.
- Domenici Enrico
- Domschke Katharina
- Douzenis Athanassios
- Drange Ole Kristian
- Duncan Laramie E.
- Dunn Erin C.
- Duriez Philibert
- Edenberg Howard J.
- Edenberg Howard J.
- Edwards Alexis C.
- Egberts Karin
- Ehrlich Stefan
- Eley Thalia C.
- Elvsåshagen Torbjørn
- Erlangsen Annette
- Escaramís Geòrgia
- Escott-Price Valentina
- Escott-Price Valentina
- Esko Tõnu
- Esko Tõnu
- Esko Tõnu
- Esko Tõnu
- Espeseth Thomas
- Estivill Xavier
- Etain Bruno
- Fanous Ayman H.
- Farmer Anne
- Favaro Angela
- Fayad Joseph
- Ferentinos Panagiotis
- Fernández-Aranda Fernando
- Fernández-Aranda Fernando
- Ferrier I. Nicol
- Fichter Manfred M.
- Fichter Manfred M.
- Finucane Hilary K.
- Fiorentino Alessia
- Fischer Krista
- Florez Hermes
- Floyd James A. B.
- Foo Jerome C.
- Foo Jerome C.
- Foretova Lenka
- Foroud Tatiana M.
- Forstner Andreas J.
- Forstner Andreas J.
- Forstner Andreas J.
- Forstner Andreas J.
- Forty Liz
- Forzan Monica
- Frank Josef
- Frank Josef
- Frank Josef
- Franklin Christopher S.
- Frei Oleksandr
- Freimer Nelson B.
- Frisén Louise
- Frye Mark
- Frye Mark
- Fullerton Janice M.
- Fullerton Janice M.
- Föcker Manuel
- Gaddy Melinda
- Gade Katrin
- Galfalvy Hanga
- Gallinger Steven
- Gallinger Steven
- Gambaro Giovanni
- Gandal Michael
- Gandal Michael J.
- Gappy Saib
- Garnham Julie
- Gaspar Héléna A.
- Gaspar Héléna A.
- Gatt Justine M.
- Gawlik Micha
- Gaziano J. Michael
- Gaziano J. Michael
- Gejman Pablo V.
- Gelernter Joel
- Gelernter Joel
- Gershon Elliot S.
- Gibson Gretchen
- Giegling Ina
- Giegling Ina
- Gill Michael
- Giuranna Johanna
- Giusti-Rodríquez Paola
- Gizer Ian R.
- Glatt Stephen J.
- Godschalk Michael
- Goes Fernando S.
- Goes Fernando S.
- Gonidakis Fragiskos
- Gordon Scott
- Gordon Scott D.
- Gordon Scott D.
- Gordon-Smith Katherine
- Gorwood Philip
- Gorwood Philip
- Grabe Hans J.
- Grabe Hans J.
- Greco Jennifer
- Green Melissa J.
- Green Melissa J.
- Greenwood Tiffany A.
- Grevet Eugenio H.
- Grigoroiu-Serbanescu Maria
- Grigoroiu-Serbanescu Maria
- Grove Jakob
- Grove Jakob
- Grove Jakob
- Guillaume Sébastien
- Guo Yiran
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- Woodside D. Blake
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- Wray Naomi R.
- Wray Naomi R.
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- Xu Wei
- Yang Jian
- Yao Shuyang
- Yeh Shing Shing
- Yilmaz Zeynep
- Yilmaz Zeynep
- Young Allan H.
- Young Hannah
- Zablocki Clement J.
- Zai Clement C.
- Zandi Peter P.
- Zeggini Eleftheria
- Zerwas Stephanie
- Zhang Futao
- Zhao Hongyu
- Zhou Hang
- Zillich Lea
- Zillich Lea
- Zipfel Stephan
- Zwart John-Anker
- Świątkowska Beata
- Świątkowska Beata
- Świątkowska Beata
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. We investigated the shared and divergent genetic architectures of SA, psychiatric disorders, and other known risk factors. Results Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained associated with SA after conditioning on psychiatric disorders and replicated in an independent cohort from the Million Veteran Program. This locus has been implicated in risk-taking behavior, smoking, and insomnia. SA showed strong genetic correlation with psychiatric disorders, particularly major depression, and also with smoking, pain, risk-taking behavior, sleep disturbances, lower educational attainment, reproductive traits, lower socioeconomic status, and poorer general health. After conditioning on psychiatric disorders, the genetic correlations between SA and psychiatric disorders decreased, whereas those with nonpsychiatric traits remained largely unchanged. Conclusions Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.Peer reviewe
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
- Author
- Adams Mark J
- Adan Roger A H
- Adolfsson Annelie Nordin
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Akil Huda
- Albani Diego
- Alda Martin
- Alexander Madeline
- Alfredsson Lars
- Als Thomas D
- Andlauer Till F M
- Ando Tetsuya
- Andreassen Ole A
- Androutsos Christos
- Anjorin Adebayo
- Anney Richard J L
- Anttila Verneri
- Arking Dan E
- Arnold Paul D
- Arranz M. J.
- Artigas Maria Soler
- Aschauer Harald
- Asherson Philip
- Backlund Lena
- Baker Jessica H
- Baldursson Gísli
- Banaschewski Tobias
- Barr Cathy L
- Barta Csaba
- Bass Nicholas
- Bauer Michael
- Baune Bernhard T
- Begemann Martin
- Belangero Sintia
- Bellgrove Mark
- Belliveau Richard A
- Bellivier Frank
- Bencko Vladimir
- Bergen Andrew W
- Bergen Sarah E
- Berger Klaus
- Berrettini Wade H
- Bettella Francesco
- Bey Katharina
- Bienvenu O Joseph
- Biernacka Joanna M
- Binder Elisabeth B
- Birgegård Andreas
- Black Donald W
- Blackwood Douglas H R
- Boomsma Dorret I
- Bramon Elvira
- Brandt Harry
- Breen Gerome
- Brown Lawrence W
- Buccola Nancy G
- Budde Monika
- Budman Cathy
- Buitelaar Jan
- Bulik Cynthia M
- Bunney William
- Burghardt Roland
- Burmeister Margit
- Burton Christie L
- Buxbaum Joseph D
- Bybjerg-Grauholm Jonas
- Byerley William
- Byrne Enda M
- Bækvad-Hansen Marie
- Bøen Erlend
- Børglum Anders D
- Cairns Murray J
- Campion Dominique
- Carlberg Laura
- Carr Vaughan J
- Casas Miquel
- Cassina Matteo
- Castelao Enrique
- Cath Danielle
- Cerrato Felecia
- Chambert Kimberly
- Cheon Keun-Ah
- Christensen Jane H
- Churchhouse Claire
- Cichon Sven
- Ciullo Valentina
- Clarke Toni-Kim
- Clementi Maurizio
- Cloninger C Robert
- Coffey Barbara J
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- Cormand Bru
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- Curtis David
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- Dale Anders M
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- Dalsgaard Søren
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- Danner Unna N
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- De Rubeis Silvia
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- Delorme Richard
- Demontis Ditte
- Denys Damiaan
- Depienne Christel
- Derks Eske M
- DeSocio Janiece E
- Di Florio Arianna
- Dick Danielle M
- Dietrich Andrea
- Dina Christian
- Direk Nese
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- Docherty Anna R
- Domenici Enrico
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- Donohoe Gary
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- Edenberg Howard J
- Egberts Karin
- Ehrenreich Hannelore
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- Zipfel Stephan
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyper-activity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. Genetic correlation analyses revealed a meaningful structure within the eight disorders, identifying three groups of inter-related disorders. Meta-analysis across these eight disorders detected 109 loci associated with at least two psychiatric disorders, including 23 loci with pleiotropic effects on four or more disorders and 11 loci with antagonistic effects on multiple disorders. The pleiotropic loci are located within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes. These findings have important implications for psychiatric nosology, drug development, and risk prediction.Peer reviewe
Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000–14 (CONCORD-3) : analysis of individual data from 258 cancer registries in 61 countries
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- Won Y. J.
- Woods R. R.
- Woronoff A. S.
- Wu T. H.
- Wu X. C.
- Wyn Huws Dyfed
- WójcikTomaszewska J.
- Yakut C. I.
- Yang L.
- Yang Y. L.
- Yi H.
- Yoshida K.
- Yoshitake M.
- You H.
- Yépez Chamorro M. C.
- Yépez J. G.
- Zadnik V.
- Zanetti R.
- Zavala D.
- Zborovskaya A. A.
- Zeissig S. R.
- Zeng H.
- Zhang B.
- Zhang J. H.
- Zhao D. L.
- Zhaolai H.
- Zhou X.
- Zhou Y.
- Zhu F. D.
- Zhu J.
- Zhuikova L. D.
- Zimmerman H. J.
- Zorzi M.
- Zvolský M.
- Ólafsdóttir E. J.
- Üçüncü N.
- Łapińska J. B.
- Šekerija M.
- Žagar T.
- Publication venue
- The Lancet Publishing Group
- Publication date
- 01/01/2022
- Field of study
Background Leukaemias comprise a heterogenous group of haematological malignancies. In CONCORD-3, we analysed
data for children (aged 0–14 years) and adults (aged 15–99 years) diagnosed with a haematological malignancy
during 2000–14 in 61 countries. Here, we aimed to examine worldwide trends in survival from leukaemia, by age and
morphology, in young patients (aged 0–24 years).
Methods We analysed data from 258 population-based cancer registries in 61 countries participating in CONCORD-3
that submitted data on patients diagnosed with leukaemia. We grouped patients by age as children (0–14 years),
adolescents (15–19 years), and young adults (20–24 years). We categorised leukaemia subtypes according to the
International Classification of Childhood Cancer (ICCC-3), updated with International Classification of Diseases
for Oncology, third edition (ICD-O-3) codes. We estimated 5-year net survival by age and morphology, with 95% CIs,
using the non-parametric Pohar-Perme estimator. To control for background mortality, we used life tables by
country or region, single year of age, single calendar year and sex, and, where possible, by race or ethnicity. All-age
survival estimates were standardised to the marginal distribution of young people with leukaemia included in the
analysis.
Findings 164563 young people were included in this analysis: 121328 (73·7%) children, 22963 (14·0%) adolescents, and
20272 (12·3%) young adults. In 2010–14, the most common subtypes were lymphoid leukaemia (28205 [68·2%] patients)
and acute myeloid leukaemia (7863 [19·0%] patients). Age-standardised 5-year net survival in children, adolescents, and
young adults for all leukaemias combined during 2010–14 varied widely, ranging from 46% in Mexico to more than
85% in Canada, Cyprus, Belgium, Denmark, Finland, and Australia. Individuals with lymphoid leukaemia had better
age-standardised survival (from 43% in Ecuador to ≥80% in parts of Europe, North America, Oceania, and Asia) than
those with acute myeloid leukaemia (from 32% in Peru to ≥70% in most high-income countries in Europe,
North America, and Oceania). Throughout 2000–14, survival from all leukaemias combined remained consistently
higher for children than adolescents and young adults, and minimal improvement was seen for adolescents and young
adults in most countries.
Interpretation This study offers the first worldwide picture of population-based survival from leukaemia in children,
adolescents, and young adults. Adolescents and young adults diagnosed with leukaemia continue to have lower
survival than children. Trends in survival from leukaemia for adolescents and young adults are important indicators
of the quality of cancer management in this age group.peer-reviewe
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
- Author
- A Gordon Robertson
- Abdullah Kahraman
- Abel Gonzalez-Perez
- Adam A Margolin
- Adam Abeshouse
- Adam Grundhoff
- Adam J Struck
- Adam J Struck
- Adam J Wright
- Adam Lambert
- Adam P Butler
- Adam P Butler
- Adel El-Naggar
- Adnan M Nagrial
- Adrian Ally
- Adrian Baez-Ortega
- Adrian Thorogood
- Adriana Salcedo
- Adrienne M Flanagan
- Ake Borg
- Akihiro Fujimoto
- Akihiro Suzuki
- Akinyemi I Ojesina
- Alain Viari
- Alan J Robertson
- Alan P Hoyle
- Alan Thompson
- Alasdair Stenhouse
- Alastair M Thompson
- Aldo Scarpa
- Alessandro Pastore
- Alex Buchanan
- Alex Buchanan
- Alexander Claviez
- Alexander J Lazar
- Alexander Martinez-Fundichely
- Alfonso Muñoz
- Alfonso Valencia
- Aliaksei Z Holik
- Alice Meng
- Alicia L Bruzos
- Allison Creason
- Allison P Heath
- Alvin Wei Tian Ng
- Alvis Brazma
- Amaro Taylor-Weiner
- Amber L Johns
- Amie Radenbaugh
- Amit G Deshwar
- Ana Dueso-Barroso
- Ana Mijalkovic Mijalkovic-Lazic
- Ana Milovanovic
- Ana Milovanovic
- Andre Kahles
- Andrea Haake
- Andrea Holbrook
- Andrea L Richardson
- Andrea Mafficini
- Andrea Ruzzenente
- Andreas Behren
- Andreas Rosenwald
- Andreia V Pinho
- Andrew Berchuck
- Andrew D Cherniack
- Andrew J Dunford
- Andrew J Mungall
- Andrew J Spillane
- Andrew Menzies
- Andrew Menzies
- Andrew P Barbour
- Andrew Tutt
- Andrew V Biankin
- Andrey Korshunov
- Andrés Lanzós
- Andy Cafferkey
- Andy G Lynch
- Angela Chou
- Angela N Brooks
- Angela Tam
- Angelica Ochoa
- Angelika N Christ
- Angelo P Dei Tos
- Anieta M Sieuwerts
- Anil K Sood
- Anita Langerød
- Anja Füllgrabe
- Anke K Bergmann
- Ann-Marie Patch
- Anna deFazio
- Anna Ehinger
- Anna Fitzgerald
- Anne Hamilton
- Anne Vincent-Salomon
- Anne Y Warren
- Anne-Lise Børresen-Dale
- Annegien Broeks
- Anthony DiBiase
- Anthony J Gill
- Anthony Ng
- Anthony R Green
- Antonia L Pritchard
- Antonio Pea
- Antonios Koures
- Aparna Prasad
- Apurva M Hegde
- Aquila Fatima
- Arcadi Navarro
- Arie B Brinkman
- Arif O Harmanci
- Arindam Maitra
- Armando Lopez-Guillermo
- Arndt Borkhardt
- Arnoud Boot
- Asger Hobolth
- Ashley Williams
- Ashton A Connor
- Atul J Butte
- Aurélien Chateigner
- Austin J Hepperla
- Axel Aretz
- Aya Sasaki-Oku
- Ayellet V Segre
- B F Francis Ouellette
- Bailey Matthew H
- Barbara Hutter
- Barbara Hutter
- Barbara Kremeyer
- Bartha M Knoppers
- Beifang Niu
- Beifang Niu
- Beifang Niu
- Benedikt Brors
- Benita Kiat Tee Tan
- Benjamin J Raphael
- Benjamin P Berman
- Benjamin Raeder
- Bernardo Rodriguez-Martin
- Bernhard Radlwimmer
- Bernice H Wong
- Beth Karlan
- Bin Tean Teh
- Bin Zhu
- Birgit Burkhardt
- Bishoy M Faltas
- Bodil Bjerkehagen
- Bogdan Czerniak
- Boris Winterhoff
- Borislav C Rusev
- Bradly G Wouters
- Brandi N Davis-Dusenbery
- Brian Craft
- Brian D O'Connor
- Brian Patrick O'Neill
- Brice Aminou
- Calvin Wing Yiu Chan
- Cameron M Soulette
- Carl Herrmann
- Carl Morrison
- Carlo Gambacorti-Passerini
- Carlos Caldas
- Carlos D Bustamante
- Carlos López-Otín
- Carlota Rubio-Perez
- Carmen Gomez
- Carolien H M van Deurzen
- Carolyn M Hutter
- Carolyn M Hutter
- Carrie Cibulskis
- Caterina Vicentini
- Catherine A Shang
- Catherine D Moser
- Catherine J Kennedy
- Catrina C Fronick
- Chad J Creighton
- Chandra Sekhar Pedamallu
- Chang Li
- Charles David Imbusch
- Charles M Perou
- Charles Saller
- Charles Short
- Charlie E Massie
- Chawalit Pairojkul
- Chen Hong
- Chen Ye
- Cheng-Zhong Zhang
- Chin-Lee Wu
- Chip Stewart
- Chip Stewart
- Chip Stewart
- Choon Kiat Ong
- Chris Lawerenz
- Chris Mitchell
- Chris Sander
- Christian von Mering
- Christiane Buchholz
- Christina K Yung
- Christina K Yung
- Christina Yau
- Christine A Iacobuzio-Donahue
- Christine Chomienne
- Christine Desmedt
- Christine P'ng
- Christof von Kalle
- Christoph Borst
- Christoph Plass
- Christopher A Miller
- Christopher Benz
- Christopher J Scarlett
- Christopher J Yoon
- Christopher K Wong
- Christopher M Lalansingh
- Christopher M Lalansingh
- Christopher Ogden
- Christopher S Foster
- Christopher Umbricht
- Christopher W Toon
- Christos Sotiriou
- Cindy Bell
- Cinzia Cantù
- Ciyue Shen
- Claes Wadelius
- Clare Verrill
- Clarissa Gerhauser
- Claudia Calabrese
- Claudio Bassi
- Claudio Luchini
- Claudiu Farcas
- Clemency Jolly
- Colin A Purdie
- Colin A Semple
- Colin C Collins
- Colin S Cooper
- Conrad R Leonard
- Constance H Li
- Corbin D Jones
- Craig Shriver
- Cristina López
- Cyriac Kandoth
- Cyril Fisher
- D Neil Hayes
- Dai-Ying Wu
- Daiming Fan
- Daisuke Komura
- Dale W Garsed
- Daniel A Leongamornlert
- Daniel Baumhoer
- Daniel Hübschmann
- Daniel J Turner
- Daniel J Weisenberger
- Daniel M Berney
- Daniel Rosebrock
- Daniel S Brewer
- Daniela S Gerhard
- Danielle Pasternack
- Darell Bigner
- Dariush Etemadmoghadam
- Darlene Lee
- Darrin F Taylor
- Dave Larson
- David A Wheeler
- David A Wheeler
- David C Wedge
- David Craft
- David D L Bowtell
- David E Neal
- David Haan
- David Haussler
- David Haussler
- David Hedley
- David Huntsman
- David I Heiman
- David J Adams
- David J Van Den Berg
- David K Chang
- David K Miller
- David Khoo
- David Mutch
- David N Louis
- David Nicol
- David Ocana
- David R Jones
- David R Jones
- David Scott
- David T Bowen
- David T W Jones
- David Tamborero
- David Torrents
- David Torrents
- David Townend
- David Vicente
- Davide Antonello
- Declan Cahill
- Denis Larsimont
- Denis Yuen
- Denise Brooks
- Deniz Demircioğlu
- Dennis C Sgroi
- Dennis Karsch
- Dennis T Maglinte
- Dennis Wigle
- Derek W Wright
- Dianne E Chadwick
- Dido Lenze
- Dieter Kube
- Dieter Weichenhan
- Dilip D Giri
- Dimitri Livitz
- Dimitri Livitz
- Dimple Chakravarty
- Ding
- Dirk Schadendorf
- Dmitry A Gordenin
- Dominik Glodzik
- Don Chalmers
- Dong Guanlan
- Dongbing Liu
- Donghoon Lee
- Donghui Tan
- Donna M Muzny
- Dorthe Grabau
- Douglas A Levine
- Douglas F Easton
- Douglas Voet
- Duncan Beardsmore
- Dursi Lewis Jonathan
- Edward W Rowe
- Eigo Shimizu
- Ekta Khurana
- Elaine R Mardis
- Electron Kebebew
- Elena Piñeiro-Yáñez
- Elena Provenzano
- Elias Campo
- Elisabet Barrera
- Elisabetta Sereni
- Elizabeth A Musgrove
- Elizabeth L Appelbaum
- Elizabeth L Christie
- Elli Papaemmanuil
- Ellrott Kyle
- Emilie Lalonde
- Eoghan Harrington
- Eric Chuah
- Eric Green
- Eric Lander
- Eric Minwei Liu
- Eric Z Ma
- Eric Z Ma
- Erik Garrison
- Erik Larsson
- Erik Mayer
- Erik N Bergstrom
- Erin Curley
- Ermin Hodzic
- Erwin G Van Meir
- Esa Pitkänen
- Esther Rheinbay
- Esther Rheinbay
- Eun Pyo Hong
- Eunjung Alice Lee
- Eva G Alvarez
- Eva Hellstrom-Lindberg
- Ewan Birney
- F Germán Rodríguez-González
- Fabien C Lamaze
- Fabien Calvo
- Fabio C P Navarro
- Faiyaz Notta
- Fan Yang
- Fan Zhang
- Faraz Hach
- Faraz Hach
- Faridah Mbabaali
- Fatima Al-Shahrour
- Federico Abascal
- Fei-Fei Liu
- Felicity Newell
- Fenglin Liu
- Fernanda Amary
- Ferran Muiños
- Florian Markowetz
- Fouad Yousif
- Francesc Muyas
- Francesco Favero
- Francisco M De La Vega
- Francisco Sanchez-Vega
- Fraser R Duthie
- Fred Sweep
- Freddie C Hamdy
- Fruzsina Molnár-Gábor
- Fumie Hosoda
- G Petur Nielsen
- G Steven Bova
- Gad Getz
- Gad Getz
- Gad Getz
- Gaetan MacGrogan
- Gaetano Finocchiaro
- Gary D Bader
- Gavin Ha
- Gavin W Wilson
- Genta Nagae
- Geoff Macintyre
- George B Hanna
- George L Mihaiescu
- Georgia Escaramis
- Georgina V Long
- Gerd Nettekoven
- German M Demidov
- German Ott
- Gerrit K Hooijer
- Gerstein Mark B
- Gert G Van den Eynden
- Getz Gad
- Ghislaine Scelo
- Giada Bonizzato
- Giampaolo Tortora
- Gilles Romieu
- Gilles Thomas
- Giovanni Marchegiani
- Gisela Mir Arnau
- Giuseppe Malleo
- Gloria M Petersen
- Gordon B Mills
- Gordon B Mills
- Gordon Saksena
- Gordon Saksena
- Gordon Saksena
- Grace Tiao
- Grace Tiao
- Graham J Mann
- Grant Sanders
- Gu Kong
- Guanming Wu
- Guido Reifenberger
- Guido Sauter
- Guillaume Bourque
- Gulietta M Pupo
- Gun Ho Jang
- Gunes Gundem
- Gunnar Rätsch
- Gurnit Atwal
- Hailei Zhang
- Haiyan Irene Li
- Han Liang
- Hana Susak
- Hans Binder
- Hans Lehrach
- Hans-Jörg Warnatz
- Hardeep K Nahal-Bose
- Hark Kyun Kim
- HarshaVardhan Doddapaneni
- Hartmut Juhl
- Harvey Pass
- Hayley C Whitaker
- Hayley J Luxton
- Hazel Burke
- Heather K Schmidt
- Heather Thorne
- Hee Jin Lee
- Heidi J Sofia
- Heidi Sofia
- Helen Davies
- Helena Kilpinen
- Helene Kretzmer
- Heng Xiong
- Henk G Stunnenberg
- Henrik Hornshøj
- Henry Lee-Six
- Hideki Ohdan
- Hidenori Ojima
- Hidewaki Nakagawa
- Hikmat Al-Ahmadie
- Hilda A Pickett
- Hirofumi Rokutan
- Hirokazu Taniguchi
- Hiroki Yamaue
- Hiroko Tanaka
- Hiromi Nakamura
- Hiroshi Aikata
- Hiroto Katoh
- Hiroyuki Aburatani
- Hitoshi Katai
- Hitoshi Nakagama
- Hojabr Kakavand
- Holger Sültmann
- Holmfridur Hilmarsdottir
- Hong Su
- Hong Xue
- Hong Xue
- Hongtu Zhu
- Hongwei Zhang
- Hongxin Zhang
- Hsiao-Wei Chen
- Huanming Yang
- Hugh Barr
- Hui Shen
- Husen M Umer
- Huy Q Dinh
- Hyung-Lae Kim
- Hyung-Lae Kim
- Hyung-Yong Kim
- Hyunghwan Kim
- Ian J Davis
- Ian Welch
- Ignacio Vázquez-García
- Ignaty Leshchiner
- Ignaty Leshchiner
- Ignaty Leshchiner
- Iker Reyes-Salazar
- Ilinca Lungu
- Ilse Rooman
- Ilya Shmulevich
- Iman Sarrafi
- Iman Sarrafi
- Ina Felau
- Ioana Cutcutache
- Irene Papatheodorou
- Irinel Popescu
- Iris Pauporté
- Iris Selander
- Isabelle Treilleux
- Isidro Cortés-Ciriano
- Ivan Borozan
- Ivana Cataldo
- Ivica Letunic
- Ivica Letunic
- Ivo Buchhalter
- Ivo Buchhalter
- Ivo G Gut
- Ivo G Gut
- Ivon Harliwong
- Izar Villasante
- Iñigo Martincorena
- J Lynn Fink
- J Robert O'Neill
- J Todd Auman
- Jaclyn Smith
- Jacqueline Boultwood
- Jacqueline E Schein
- Jaegil Kim
- Jake June-Koo Lee
- Jakob Skou Pedersen
- Jakob Skou Pedersen
- James E Haber
- James G Kench
- James Gossage
- James S Wilmott
- Jan Komorowski
- Jan O Korbel
- Janae V Simons
- Jane E Brock
- Janet S Graham
- Janet S Rader
- Jared T Simpson
- Jared T Simpson
- Jason Huse
- Jaswinder S Samra
- Javier Bartolome
- Javier Bartolomé Rodriguez
- Javier Temes
- Jean C Zenklusen
- Jean Y Yang
- Jean-Rémi Trotta
- Jeffrey A Wintersinger
- Jeffrey Boyd
- Jeffrey E Gershenwald
- Jeffrey Marks
- Jeffrey Roach
- Jenna Eagles
- Jennifer L Jennings
- Jeong-Yeon Lee
- Jeremiah A Wala
- Jeremiah A Wala
- Jeremy Chien
- Jeremy Johns
- Jerome Myers
- Jesper Lagergren
- Jessica I Hoell
- Jessica K Miller
- Ji Wan Park
- Jia Liu
- Jian Wang
- Jianhong Hu
- Jianjiong Gao
- Jianmin Wu
- Jiashan Zhang
- Jiayin Wang
- Jiayin Wang
- Jieming Chen
- Jihoon Kim
- Jill Barnholtz-Sloan
- Jillian A Hung
- Jing Zhang
- Jingchun Zhu
- Joachim Weischenfeldt
- Joachim Weischenfeldt
- Joan Frigola
- Joana Carlevaro-Fita
- Jocelyne Jacquemier
- Joel S Parker
- Johan Staaf
- Johann S De Bono
- Johanna Bertl
- Johannes Werner
- Johannes Werner
- John A Demchok
- John A Foekens
- John Bartlett
- John Busanovich
- John D McPherson
- John F Thompson
- John Letaw
- John N Weinstein
- John N Weinstein
- John R McPherson
- John V Pearson
- John W M Martens
- Jon G Jonasson
- Jon W Teague
- Jon W Teague
- Jonas Demeulemeester
- Jonathan Barenboim
- Jonathan Cebon
- Jonathan D Kay
- Jonathan Göke
- Jonathan Hinton
- Jonathan Hinton
- Jonathan Nicholson
- Jonathan R Stretch
- Jonathan Spring
- Jonathan Warrell
- Jong K Kim
- Jongsun Jung
- Jongsun Jung
- Jongwhi H Hong
- Joong-Won Park
- Jordi Deu-Pons
- Jorge Reis-Filho
- Jorge Zamora
- Jorunn E Eyfjord
- Jos Jonkers
- Jose I Martin-Subero
- Jose M C Tubio
- Jose M G Izarzugaza
- Josep L L Gelpi
- Josep L L Gelpi
- Joshua Armenia
- Joshua M Stuart
- Joshua M Stuart
- Joshy George
- José María Heredia-Genestar
- Joy C Jayaseelan
- Juergen Eils
- Juhee Lee
- Jules N A Kerssemakers
- Julia Markowski
- Julia Richter
- Julian M Hess
- Julian M Hess
- Julian M Hess
- Juliann Shih
- Julie Livingstone
- Julie M Wilson
- Jun Li
- Jun Yu
- Jung Kyoon Choi
- Junjun Zhang
- Junjun Zhang
- Juok Cho
- Juris Viksna
- Justin P Whalley
- Jyoti Nangalia
- Jörg Tost
- Jüri Reimand
- K Vijay Raghavan
- Kadir C Akdemir
- Kai Ye
- Kai Ye
- Kai Ye
- Kaixian Yu
- Kami Chiotti
- Kamna Ramakrishnan
- Kaoru Nakano
- Karen McCune
- Karen Mungall
- Karen Smith-McCune
- Karin A Oien
- Karin S Kassahn
- Karine Jegalian
- Karolina Czajka
- Karsten Rippe
- Katalin Karaszi
- Katarzyna O Sikora
- Katayoon Kasaian
- Katayoon Kasaian
- Katherine A Hoadley
- Kathleen H Burns
- Kathleen Marchal
- Kathryn Alsop
- Katia Nones
- Kazuaki Chayama
- Kazuhiro Maejima
- Kazuhiro Ohi
- Ke Yuan
- Keiran M Raine
- Keiran M Raine
- Keith A Boroevich
- Kelso Sean
- Ken Chen
- Ken Chen
- Ken Dutton-Regester
- Kenji Tatsuno
- Kenneth Aldape
- Keren Isaev
- Kerstin Haase
- Keun Soo Ahn
- Keunchil Park
- Kevin J Dawson
- Kevin Thai
- Kiejung Park
- Kin Chan
- Kiran Kumar
- Kirsten Kübler
- Kiyo Shimizu
- Kjong-Van Lehmann
- Klev Diamanti
- Koji Arihiro
- Koo Jeong Kang
- Kortine Kleinheinz
- Kortine Kleinheinz
- Kristian Cibulskis
- Kuan-Lin Huang
- Kui Wu
- Kunihito Gotoh
- Kwun M Fong
- Kyle Covington
- Kyle Covington
- Kyle Ellrott
- Kyle Ellrott
- Kyle Ellrott
- L Van't Veer
- Lara Jerman
- Lara Urban
- Lars Feuerbach
- Larsson Omberg
- Laura Planko
- Laurence B Lovat
- Laurent Arnould
- Lauri A Aaltonen
- Lawrence E Heisler
- Layla Oesper
- Lee E Timms
- Lei Song
- Leigh B Thorne
- Leng Han
- Leonidas Salichos
- Leslie Cope
- Leszek J Klimczak
- Levi Garraway
- Lewis Jonathan Dursi
- Lewis Jonathan Dursi
- Lewis R Roberts
- Li Ding
- Li Ding
- Li Ding
- Li Shantao
- Liang Wen-Wei
- Liangtao Zheng
- Lieven P C Verbeke
- Lihua Zou
- Liis Uusküla-Reimand
- Liliana Greger
- Liming Yang
- Lin Li
- Lina Sieverling
- Lina Wadi
- Lincoln D Stein
- Linda Mileshkin
- Linghua Wang
- LiRehan Akbani
- Lisa Lype
- Lisa Mirabello
- Lisle E Mose
- Liu Xi
- Liu Xi
- Lixing Yang
- Lora Lewis
- Lorenz H P Trümper
- Loretta M S Lau
- Lori Boice
- Loris Mularoni
- Lorraine A Chantrill
- Louis Letourneau
- Luc Dirix
- Luca Landoni
- Luca Malcovati
- Lucas Lochovsky
- Lucila Ohno-Machado
- Lucinda A Fulton
- Lucy Matthews
- Lucy Stebbings
- Lucy Stebbings
- Lucy Yates
- Ludmil B Alexandrov
- Ludmila Danilova
- Luisa Mantovani-Löffler
- Luke Marsden
- Maciej Wiznerowicz
- Malcolm Brock
- Malcolm J Moore
- Malene Juul
- Malik Alawi
- Mamoru Kato
- Manasa Ramakrishna
- Manaswi Gupta
- Manolis Kellis
- Manuel Prinz
- Mara Rosenberg
- Marat D Kazanov
- Marc D Perry
- Marc D Perry
- Marc J van de Vijver
- Marc Zapatka
- Marcel Kool
- Marcel Smid
- Marcin Imielinski
- Marco A Marra
- Marco Miotto
- Marcus Bosenberg
- Marek Cmero
- Maria Elisabeth Goebler
- Maria Keays
- Maria O'Donovan
- Maria Scardoni
- Maria Vittoria Davi
- Marie-Laure Yaspo
- Marina Pajic
- Mario Berrios
- Mario Cazzola
- Marius Rohde
- Mark A Rubin
- Mark B Gerstein
- Mark B Gerstein
- Mark H Wright
- Mark Lathrop
- Mark P Hamilton
- Mark Phillips
- Mark Pinese
- Mark Shackleton
- Markus B Schilhabel
- Markus Kreuz
- Markus Loeffler
- Markus Ringnér
- Marta Aymerich
- Marta Gut
- Marta Paczkowska
- Marta Tojo
- Martin Hansmann
- Martin L Ferguson
- Martin Peifer
- Mary J Goldman
- Masakazu Yamamoto
- Masaki Ueno
- Masashi Fujita
- Masashi Fukayama
- Matteo Fassan
- Matthew A Field
- Matthew A Reyna
- Matthew D Wilkerson
- Matthew Eldridge
- Matthew G Cordes
- Matthew G Soloway
- Matthew H Bailey
- Matthew H Bailey
- Matthew H Bailey
- Matthew J Anderson
- Matthew Meyerson
- Matthew R Huska
- Matthew Ringel
- Matthew W Fittall
- Matthias Bieg
- Matthias Bieg
- Matthias Schlesner
- Matthias Schlesner
- Mattia Bosio
- Maxime Tarabichi
- Maximillian G Marin
- Mayuko Furuta
- Mei Huang
- Melpomeni Kasapi
- Meyerson William U
- Mi Ni Huang
- Mia Nastic
- Michael A Hollingsworth
- Michael Birrer
- Michael C Heinold
- Michael C Heinold
- Michael C Quinn
- Michael C Wendl
- Michael C Wendl
- Michael D McLellan
- Michael D McLellan
- Michael D McLellan
- Michael Dunn
- Michael Fraser
- Michael H A Roehrl
- Michael Hummel
- Michael Ittmann
- Michael Kneba
- Michael Koscher
- Michael Mayo
- Michael R Stratton
- Michael S Lawrence
- Michael S Noble
- Michele Milella
- Michele Simbolo
- Michelle Chan-Seng-Yue
- Michelle Sam
- Michelle T Dow
- Miguel Betancourt
- Miguel Vazquez
- Mihoko Saito-Adachi
- Milana Frenkel-Morgenstern
- Milena Kovacevic
- Ming Ta Michael Lee
- Ming Tsao
- Miranda D Stobbe
- Miranda D Stobbe
- Miriam R Aure
- Miruna Balasundaram
- Mitsuhiro Komura
- Mohamed Helmy
- Mohammed Ghori
- Moiz S Bootwalla
- Monika Szczepanowski
- Monique Albert
- Montserrat Puiggròs
- Montserrat Puiggròs
- Morgan L Taschuk
- Moritz Gerstung
- Morten Muhlig Nielsen
- Morten Muhlig Nielsen
- Murat Iskar
- Myron Peto
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- W Kimryn Rathmell
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- Wan Choi
- Wanding Zhou
- Wang Liang-Bo
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- Wei Jiao
- Wendl Michael C
- Wenyi Wang
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- Wheeler David A
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- Xing Hua
- Xingmin Liu
- Xinyue Li
- Xiuqing Zhang
- Xiuqing Zheng
- Xose S Puente
- Xuan Le
- Xuanping Zhang
- Xuemei Luo
- Xueqing Zou
- Yan Shi
- Yan Zhang
- Yang Wu
- Yang Yang
- Yann Joly
- Yanxun Xu
- Yao He
- Yasin Senbabaoglu
- Yassen Assenov
- Yasser Riazalhosseini
- Yasuhito Arai
- Yasushi Rino
- Yasushi Totoki
- Yeng Ang
- Yi Huang
- Yi Huang
- Yifei Men
- Yiling Lu
- Yilong Li
- Yingyan Yu
- Yiwen Chen
- Yogesh Kumar
- Yogesh Kumar
- Yoke-Eng Chiew
- Yong Hou
- Yong Zhou
- Yong-Jie Lu
- Yongzhan Nie
- Yosef E Maruvka
- Yosef E Maruvka
- Yoshiiku Kawakami
- Young Seok Ju
- Youngchoon Woo
- Youngil Koh
- Youngwook Kim
- Youyong Lu
- Yu Fan
- Yu Fan
- Yu Fan
- Yu-Jia Shiah
- Yuan Ji
- Yuan Yuan
- Yuichi Shiraishi
- Yulia Newton
- Yulia Rubanova
- Yumeng Wang
- Yupeng Cun
- Yussanne Ma
- Zachary Heins
- Zechen Chong
- Zechen Chong
- Zemin Zhang
- Zhaohong Chen
- Zhenggang Wu
- Zhenggang Wu
- Zhining Wang
- Zhongming Zhao
- Ziao Lin
- Zsofia Kote-Jarai
- Ólafur Andri Stefánsson
- Øystein Garred
- Publication venue
- Nature Communications
- Publication date
- 01/01/2020
- Field of study
Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts
Underlying Event measurements in pp collisions at s=0.9 and 7 TeV with the ALICE experiment at the LHC
- Author
- A Buckley
- A Capella
- A. Kurepin
- A.B. Kurepin
- A.K. Dutta Majumdar
- Abdiel Ramirez Reyes
- Adam Ryszard Kisiel
- Adam Tomasz Matyja
- Adam Wlodzimierz Jacholkowski
- Aditya Nath Mishra
- Adrian Sevcenco
- Adriana Telesca
- Airton Deppman
- Ajay Kumar Dash
- Ajit Kumar Mohanty
- AK Aamodt
- Alain Baldit
- Alain Michalon
- Alberica Toia
- Alberto Baldisseri
- Alberto Gago
- Alberto Masoni
- Alberto Pulvirenti
- Alejandro Szanto de Toledo
- Alessandra Fantoni
- Alessandra Maria Mazzoni
- Alessandro De Falco
- Alessandro Ferretti
- Alessandro Grelli
- Alessandro Pesci
- Alexander Akindinov
- Alexander Borissov
- Alexander Hansen
- Alexander Kluge
- Alexander Mamonov
- Alexander Nedosekin
- Alexander Ochirov
- Alexander Philipp Kalweit
- Alexander Vinogradov
- Alexander Vodopianov
- Alexander Wilk
- Alexandr Tumkin
- Alexandre Alarcon do Passo Suaide
- Alexandre Nyanin
- Alexandre Rachevski
- Alexandre Shabetai
- Alexandru Bercuci
- Alexandru Florin Dobrin
- Alexei Kaidalov
- Alexei Khanzadeev
- Alexei Pavlinov
- Alexey Bogdanov
- Alexey Kuryakin
- Alexey Vyushin
- Alexis Jean-Michel Mas
- Alfredo Musso
- Alice Zimmermann
- Alina Gabriela Grigoras
- Alla Maevskaya
- Alphonse Rademakers
- Amalia Pop
- Amaya Ofelia Casanova Diaz
- Ana Maria Marin
- Anand Kumar Dubey
- Anatoly Fedunov
- Anatoly Kolojvari
- Anders Nils Erik Oskarsson
- Andras Gabor Agocs
- Andre Augustinus
- Andre Mischke
- Andrea Agostinelli
- Andrea Alici
- Andrea Dainese
- Andrea Danu
- Andrea De Azevedo Moregula
- Andrea Rossi
- Andreas Arend
- Andreas Morsch
- Andrei George Gheata
- Andrei Ionut Herghelegiu
- Andres Sandoval
- Andrew Marshall Adare
- Andrey Ivanov
- Andrey Kazantsev
- Andrey Korneev
- Andrey Reshetin
- Andrey Vasiliev
- Andrey Zarochentsev
- Andry Malala Rakotozafindrabe
- Andrzej Deloff
- Andrzej Rybicki
- Andzhey Asryan
- Angela Badala
- Anik Gupta
- Anitha Nyatha
- Anju Bhasin
- Ankita Goswami
- Anna Piccotti
- Anna Rita Reolon
- Annalisa De Caro
- Annalisa Mastroserio
- Annika Passfeld
- Anselmo Margotti
- Ante Bilandzic
- Anthony Timmins
- Antoine Xavier Lardeux
- Anton Alkin
- Anton Andronic
- Anton Jusko
- Antonin Maire
- Antonino Zichichi
- Antonio Di Mauro
- Antonio Juan Rubio Montero
- Antonio Ortiz Velasquez
- Antonio Uras
- Ara Grigoryan
- Arian Abrahantes Quintana
- Armando Palmeri
- Arnulfo Martinez Davalos
- Arsen Hayrapetyan
- Arshad Ahmad
- Artem Konevskih
- Artur Krzysztof Szostak
- Arturo Alejandro Menchaca-Rocha
- Arturo Fernandez Tellez
- Arturo Tauro
- Arvinder Singh Palaha
- Ashok Kumar Bhati
- Aurora Diozcora Vargas
- Ayben Karasu Uysal
- B Andersson
- Baba Potukuchi
- Barbara Guerzoni
- Barthelemy von Haller
- Basanta Kumar Nandi
- Bastian Bathen
- Bedangadas Mohanty
- Benjamin Donigus
- Beomkyu Kim
- Beomsu Chang
- Bernard Hicks
- Bernd Stefan Windelband
- Bernhard Skaali
- Betty Abelev
- Bikash Sinha
- Bjarte Kileng
- Bjorn Steven Nilsen
- Blahoslav Pastircak
- Bogdan Theodor Rascanu
- Bogdan Vulpescu
- Borge Svane Nielsen
- Boris Batyunya
- Boris Grinyov
- Boris Hippolyte
- Boris Polichtchouk
- Boris Wagner
- Branislav Sitar
- Brigitte Cheynis
- Brijesh Kumar Srivastava
- Bruno Alessandro
- Bruno Alexandre Boyer
- Bruno Espagnon
- Bruno Ghidini
- Byounghee Han
- Camilo Andres Carrillo Montoya
- Camilo Ernesto Lara
- Carlos Albert Salgado
- Carlos Eugenio Perez Lara
- Carlos Pajares
- Carmelo Di Giglio
- Carsten Sogaard
- Casper Nygaard
- Catia Petta
- Cenek Zach
- Cesar Guerra Gutierrez
- Chamath Kottachchi Kankanamge Don
- Chiara Bianchin
- Chiara Oppedisano
- Chiara Zampolli
- Christelle Sophie Roy
- Christian Claude Kuhn
- Christian Holm Christensen
- Christian Joachim Schmidt
- Christian Klein-Bosing
- Christian Lippmann
- Christina Markert
- Christine Nattrass
- Christoph Blume
- Christoph Heinrich Baumann
- Christoph Mayer
- Christophe Furget
- Christophe Pierre Suire
- Christopher Daniel Anson
- Christos Tagridis
- Cinzia Luzzi
- Ciprian Mihai Mitu
- Claude Andre Pruneau
- Claudio Bortolin
- Claudio Geuna
- Claudiu Cornel Schiaua
- Constantinos Loizides
- Corrado Cicalo
- Costanza Cavicchioli
- Costin Grigoras
- Crispin Williams
- Cristian Andrei
- Cristian George Ivan
- Cristina Lazzeroni
- Cristina Terrevoli
- Csaba Soos
- Cvetan Cheshkov
- Cynthia Marie Hadjidakis
- Cyrano Bergmann
- D Acosta
- Dae Sung Hwang
- Dagmar Adamova
- Daicui Zhou
- Daniel Berenyi
- Daniel Felea
- Daniel Jesus Tapia Takaki
- Daniel Lohner
- Daniel Mayani
- Daniela Fabris
- Daniele De Gruttola
- Danilo Vranic
- Danthasinghe Piyarathna
- Dario Berzano
- Dariusz Miskowiec
- David Chinellato
- David Christopher Truesdale
- David Evans
- David Olle Rickard Silvermyr
- David Philip Emschermann
- David Rohr
- David Tlusty
- Davide Caffarri
- Davide Falchieri
- Davide Perrino
- Debasish Das
- Deepa Thomas
- Deepika Rathee
- Denise Aparecida Moreira De Godoy
- Despoina Hatzifotiadou
- Dhevan Raja Gangadharan
- Diego Perini
- Diego Stocco
- Dieter Rohrich
- Dilan Minthaka Madagodahettige-Don
- Dmitri Ivanovich Patalakha
- Dmitri Peresunko
- Dmitry Aleksandrov
- Dmitry Blau
- Dmitry Budnikov
- Dmitry Finogeev
- Dmitry Mal’Kevich
- Do Won Kim
- Domenico Colella
- Domenico Di Bari
- Domenico Elia
- Dominik Fehlker
- Don Constantin Vernekohl
- Dong Jo Kim
- Dong Wang
- Dosatsu Sakata
- Dumitru Hasegan
- Durga Prasad Mahapatra
- Edgar Perez Lezama
- Edith Zinhle Buthelezi
- Edmundo Garcia-Solis
- Eduardo Del Castillo Sanchez
- Eleazar Cuautle
- Elena Bruna
- Elena Gonzalez Ferreiro
- Elienos Pereira De Oliveira Filho
- Elisa Incani
- Elisabetta Crescio
- Emanuele Quercigh
- Emilia Cruz Alaniz
- Emilio Chiavassa
- Enrichetta Maria Fiore
- Enrico Fragiacomo
- Enrico Scomparin
- Erick Jonathan Almaraz Avina
- Ermanno Vercellin
- Ernesto Belmont-Moreno
- Ernesto Calvo Villar
- Ernesto Lopez Torres
- Ervin Denes
- Ester Anna Rita Casula
- Esther Montes
- Eugen Mudnic
- Eugenio Nappi
- Eugenio Scapparone
- Eulogio Serradilla
- Eva Sicking
- Evert Anders Stenlund
- Evgeny Karpechev
- Evgeny Kryshen
- Evgeny Ryabinkin
- Ewa Gladysz-Dziadus
- F. Blanco
- Fabio Colamaria
- Fabrizio Coccetti
- Fatima Padilla
- Federico Antinori
- Federico Carminati
- Federico Cindolo
- Federico Ronchetti
- Fedor Guber
- Felix Vincenz Rettig
- Fengchu Zhou
- Fernando Baltasar Dos Santos Pedrosa
- Fernando Scarlassara
- Filimon Roukoutakis
- Filip Krizek
- Filippo Costa
- Fiorella Fionda
- Flavio Tosello
- Florian Painke
- Francesca Bellini
- Francesca Soramel
- Francesco Barile
- Francesco Blanco
- Francesco Bossu
- Francesco Carena
- Francesco Noferini
- Francesco Prino
- Francesco Riggi
- Franck Manso
- Franco Meddi
- Francois Piuz
- Frederic Lefevre
- Frederick Kramer
- G Aad
- G Aad
- Gabriel de Barros
- Galina Shabratova
- Gaute vrebekk
- Gennady Zinovjev
- Gerardo Antonio Herrera Corral
- Gerardus Nooren
- Gergely Gabor Barnafoldi
- Gergoe Hamar
- Giacinto de Cataldo
- Giacomo Contin
- Giacomo Ortona
- Giacomo Vito Margagliotti
- Giacomo Volpe
- Gian Michele Innocenti
- Gianfranco Segato
- Gianluca Aglieri Rinella
- Gianluca Usai
- Gideon Francois Steyn
- Gilda Scioli
- Gines Martinez Garcia
- Ginevra D’Erasmo
- Giorgio Stefanini
- Giovanna Puddu
- Giovanni Cara Romeo
- Giuseppe Eugenio Bruno
- Giuseppe Pappalardo
- Giuseppe Simonetti
- Giuseppe Viesti
- Gleb Nazarov
- Grazia Luparello
- Greeshma Koyithatta Meethaleveedu
- Grigory Feofilov
- Grzegorz Andrzej Wilk
- Grzegorz Stefanek
- Guido Marie Urciuoli
- Guillaume Batigne
- Guillermo Tejeda Munoz
- Gunnar Lovhoiden
- Gustavo Conesa Balbastre
- Guy Paic
- Gyulnara Eyyubova
- Haavard Helstrup
- Haeng Jin Jang
- Hanna Paulina Zbroszczyk
- Hans Beck
- Hans Boggild
- Hans Gutbrod
- Hans Hjersing Dalsgaard
- Hans Muller
- Hans Rudolf Schmidt
- Harald Appelshauser
- Hege Austrheim Erdal
- Heiko Engel
- Helen Louise Caines
- Helmut Oskar Oeschler
- Henner Buesching
- Henning Kvaerno
- Henrik Qvigstad
- Hermes Leon
- Hermes Leon Vargas
- Herve Borel
- Hideki Hamagaki
- Hideyuki Obayashi
- Hiroaki Sakaguchi
- Hiroki Yokoyama
- Hisayuki Torii
- Hongyan Yang
- Hugues Delagrange
- Hyung Taik Jung
- Hyungsuk Son
- Ian Gardner Bearden
- Igor Altsybeev
- Igor Lakomov
- Igor Pshenichnov
- Igor Yushmanov
- Ildefonso Leon Monzon
- Ilya Selioujenkov
- Imrich Szarka
- In-Kwon Yoo
- Indranil Das
- Ingrid Christine Kraus
- Ingvar Otterlund
- Ionel Stan
- Ionel Stan
- Ionela Berceanu
- Ionut Cristian Arsene
- Iouri Belikov
- Irakli Garishvili
- Irakli Martashvili
- Irene Sgura
- Iryna Ilkiv
- Isabel Dominguez
- Ismael Cortes Maldonado
- Ivan Kisel
- Ivan Kralik
- Ivana Hrivnacova
- Ivonne Alicia Maldonado Cervantes
- Iwona Sputowska
- Jacek Tomasz Otwinowski
- Jan Cepila
- Jan de Cuveland
- Jan Fiete Grosse-Oetringhaus
- Jan Figiel
- Jan Marian Pluta
- Jan Rak
- Jana Bielcikova
- Janka Vrlakova
- Janusz Oleniacz
- Jaroslav Ban
- Jaroslav Bielcik
- Jason Glyndwr Ulery
- Javier Ernesto Castillo Castellanos
- Jean Willy Andre Cleymans
- Jean-Luc Fernand Charvet
- Jean-Pierre Michel Coffin
- Jean-Pierre Revol
- Jean-Sebastien Real
- Jean-Yves Grossiord
- Jeewon Seo
- Jennifer Lynn Klay
- Jens Joergen Gaardhoje
- Jens Wiechula
- Jerzy Gustaw Bartke
- Jesus Guillermo Contreras
- Jiebin Luo
- Jihye Song
- Jim Thomas
- Jin Sook Kim
- Jiri Kral
- Jiri Mares
- Joakim Ingemar Nystrand
- Jocelyn Mlynarz
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Exploring the relationships between motivation, attachment and loyalty within sport event tourism
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- 'Informa UK Limited'
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- Field of study
- …