583 research outputs found
COBRA: a new European research project for organic plant breeding
Development of organic plant breeding and seed production will have a valuable impact on organic plant production. Breeding of plant material adapted for organic agriculture is crucial in order to cope with stresses such as climate change, weeds and seed borne diseases. Conventional varieties may not meet the specific needs of organic agriculture. The use of plant material adapted to conditions of organic agriculture will have a positive effect on the productivity and sustainability of organic crop production
Potato variety diversity, determinants and Implications for potato breeding strategy in Ethiopia.
Understanding what farmers need in potato varieties and assessing available genetic resources at the farmer and district levels is important for the conservation and improvement of potato in Ethiopia. A survey was conducted in six major potato growing districts representing different agro-ecologies, cropping systems, market outlets, and levels of new variety adoption. Seventy to ninety percent of the farmers surveyed reported growing two or more potato varieties; some farmers reported growing up to five. The greatest diversity at the district level (up to 10 potato varieties) was recorded at Gumer & Geta where there is better access to new varieties while the lowest diversity was reported in districts with low access to new cultivars. The distribution of varieties differed among agro-ecologies as did the traits that farmers were most concerned with, such as drought tolerance, late blight resistance, yield potential, marketability, food value, storage quality, adaptation to low soil fertility, time to maturity and suitability for multiple harvesting. Farmers’ decision-making processes and external factors that influence potato variety diversity were also documented. The registration of predominant local varieties and use of these local varieties as a starting point for the development of improved varieties are some of the recommendations for future potato breeding in Ethiopia. Moreover, it is necessary to consider variations in agro-ecologies, cropping systems and market outlets in the process of developing varieties suitable for farmers’ and consumers’ real needs
Mixed Models with n>1 and Large Scale Structure constraints
Recent data on CBR anisotropies show a Doppler peak higher than expected in
CDM cosmological models, if the spectral index . However, CDM and LCDM
models with n>1 can hardly be consistent with LSS data. Mixed models, instead,
whose transfer function is naturally steeper because of free--streaming in the
hot component, may become consistent with data if n>1, when Omega_h is large.
This is confirmed by our detailed analysis, extended both to models with a hot
component whose momentum space distribution had a thermal origin (like massive
neutrinos), and to models with a non--cold component arising from heavier
particle decay. In this work we systematically search models which fulfill all
constraints which can be implemented at the linear level. We find that a
stringent linear constraint arises from fitting the extra-power parameter
Gamma. Other significant constraints arise comparing the expected abundances of
galaxy clusters and high-z systems with observational data. Keeping to models
with Gamma \geq 0.13, a suitable part of the space parameter still allows up to
\sim 30% of hot component (it is worth outlining that our stringent criteria
allow only models with 0.10 \mincir Omega_h \mincir 0.16, if n \leq 1). We also
outline that models with such large non--cold component would ease the solution
of the so--called baryon catastrophe in galaxy clusters.Comment: 28 pages + 9 figures, uses elsart.sty, to be published in New
Astronom
A lattice model for the kinetics of rupture of fluid bilayer membranes
We have constructed a model for the kinetics of rupture of membranes under
tension, applying physical principles relevant to lipid bilayers held together
by hydrophobic interactions. The membrane is characterized by the bulk
compressibility (for expansion), the thickness of the hydrophobic part of the
bilayer, the hydrophobicity and a parameter characterizing the tail rigidity of
the lipids. The model is a lattice model which incorporates strain relaxation,
and considers the nucleation of pores at constant area, constant temperature,
and constant particle number. The particle number is conserved by allowing
multiple occupancy of the sites. An equilibrium ``phase diagram'' is
constructed as a function of temperature and strain with the total pore surface
and distribution as the order parameters. A first order rupture line is found
with increasing tension, and a continuous increase in proto-pore concentration
with rising temperature till instability. The model explains current results on
saturated and unsaturated PC lipid bilayers and thicker artificial bilayers
made of diblock copolymers. Pore size distributions are presented for various
values of area expansion and temperature, and the fractal dimension of the pore
edge is evaluated.Comment: 15 pages, 8 figure
Measurement of (anti)deuteron and (anti)proton production in DIS at HERA
The first observation of (anti)deuterons in deep inelastic scattering at HERA
has been made with the ZEUS detector at a centre-of-mass energy of 300--318 GeV
using an integrated luminosity of 120 pb-1. The measurement was performed in
the central rapidity region for transverse momentum per unit of mass in the
range 0.3<p_T/M<0.7. The particle rates have been extracted and interpreted in
terms of the coalescence model. The (anti)deuteron production yield is smaller
than the (anti)proton yield by approximately three orders of magnitude,
consistent with the world measurements.Comment: 26 pages, 9 figures, 5 tables, submitted to Nucl. Phys.
Observation of Orbitally Excited B_s Mesons
We report the first observation of two narrow resonances consistent with
states of orbitally excited (L=1) B_s mesons using 1 fb^{-1} of ppbar
collisions at sqrt{s} = 1.96 TeV collected with the CDF II detector at the
Fermilab Tevatron. We use two-body decays into K^- and B^+ mesons reconstructed
as B^+ \to J/\psi K^+, J/\psi \to \mu^+ \mu^- or B^+ \to \bar{D}^0 \pi^+,
\bar{D}^0 \to K^+ \pi^-. We deduce the masses of the two states to be m(B_{s1})
= 5829.4 +- 0.7 MeV/c^2 and m(B_{s2}^*) = 5839.7 +- 0.7 MeV/c^2.Comment: Version accepted and published by Phys. Rev. Let
Statins for extension of disability-free survival and primary prevention of cardiovascular events among older people: protocol for a randomised controlled trial in primary care (STAREE trial)
Introduction: The world is undergoing a demographic transition to an older population. Preventive healthcare has reduced the burden of chronic illness at younger ages but there is limited evidence that these advances can improve health at older ages. Statins are one class of drug with the potential to prevent or delay the onset of several causes of incapacity in older age, particularly major cardiovascular disease (CVD). This paper presents the protocol for the STAtins in Reducing Events in the Elderly (STAREE) trial, a randomised double-blind placebo-controlled trial examining the effects of statins in community dwelling older people without CVD, diabetes or dementia. Methods and analysis: We will conduct a double-blind, randomised placebo-controlled trial among people aged 70 years and over, recruited through Australian general practice and with no history of clinical CVD, diabetes or dementia. Participants will be randomly assigned to oral atorvastatin (40 mg daily) or matching placebo (1:1 ratio). The co-primary endpoints are disability-free survival defined as survival-free of dementia and persistent physical disability, and major cardiovascular events (cardiovascular death or non-fatal myocardial infarction or stroke). Secondary endpoints are all-cause death, dementia and other cognitive decline, persistent physical disability, fatal and non-fatal myocardial infarction, fatal and non-fatal stroke, heart failure, atrial fibrillation, fatal and non-fatal cancer, all-cause hospitalisation, need for permanent residential care and quality of life. Comparisons between assigned treatment arms will be on an intention-to-treat basis with each of the co-primary endpoints analysed separately in time-to-first-event analyses using Cox proportional hazards regression models. Ethics and dissemination: STAREE will address uncertainties about the preventive effects of statins on a range of clinical outcomes important to older people. Institutional ethics approval has been obtained. All research outputs will be disseminated to general practitioner co-investigators and participants, published in peer-reviewed journals and presented at national and international conferences. Trial registration number: NCT02099123.Sophia Zoungas, Andrea Curtis, Simone Spark, Rory Wolfe, John J McNeil, Lawrence Beilin, Trevor T-J Chong, Geoffrey Cloud, Ingrid Hopper, Alissia Kost, Mark Nelson, Stephen J Nicholls, Christopher M Reid, Joanne Ryan, Andrew Tonkin, Stephanie A Ward, Anthony Wierzbicki, On behalf of STAREE investigator grou
On the Holographic RG-flow and the Low-energy, Strong Coupling, Large N Limit
From the AdS/CFT correspondence, we learn that the classical evolution of
supergravity in the bulk can be reduced to a RG-flow equation for the dual
low-energy, strongly coupled and large N gauge theory on the boundary. This
result has been used to obtain interesting relations between the various terms
in the gravitational part of the boundary effective action, in particular the
term that affect the cosmological constant. It is found that once the
cosmological constant is cancelled in the UV theory, the RG-flow symmetry of
the boundary effective action automatically implies the existence of zero
cosmological constant solutions that extend all the way into the IR. Given the
standard (and well founded) contradiction between the RG-flow idea and the
observational evidence of a small cosmological constant, this is considered to
be an important progress, albeit incomplete, towards the final solution.
Motivated by this success, it would be interesting to see whether this
RG-stability extends outside the scope of strong 't Hooft coupling and large N
regime that are implicitly assumed in the de Boer-Verlinde-Verlinde
Hamilton-Jacobi formulation of the holographic RG-flow equations of the
boundary theory. In this paper, we address this question. Taking into account
the leading order corrections in the 1/N and parameters, we
derive new bulk/boundary relations, from which one can read all the local terms
in the boundary effective action. Next, we use the resulting constraints, to
examine whether the RG-stability of the cosmological constant extends to the
new coupling regime. It would be also interesting to use these constraints to
study the Randall-Sundrum scenario in this case.Comment: 27 pages, LateX, no figures, minor changes, typos corrected and added
more reference
Nucleosomes in gene regulation: theoretical approaches
This work reviews current theoretical approaches of biophysics and
bioinformatics for the description of nucleosome arrangements in chromatin and
transcription factor binding to nucleosomal organized DNA. The role of
nucleosomes in gene regulation is discussed from molecular-mechanistic and
biological point of view. In addition to classical problems of this field,
actual questions of epigenetic regulation are discussed. The authors selected
for discussion what seem to be the most interesting concepts and hypotheses.
Mathematical approaches are described in a simplified language to attract
attention to the most important directions of this field
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