18 research outputs found

    The burden of unintentional drowning: Global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study

    Get PDF
    __Background:__ Drowning is a leading cause of injury-related mortality globally. Unintentional drowning (International Classification of Diseases (ICD) 10 codes W65-74 and ICD9 E910) is one of the 30 mutually exclusive and collectively exhaustive causes of injury-related mortality in the Global Burden of Disease (GBD) study. This study's objective is to describe unintentional drowning using GBD estimates from 1990 to 2017. __Methods:__ Unintentional drowning from GBD 2017 was estimated for cause-specific mortality and years of life lost (YLLs), age, sex, country, region, Socio-demographic Index (SDI) quintile, and trends from 1990 to 2017. GBD 2017 used standard GBD methods for estimating mortality from drowning. __Results:__ Globally, unintentional drowning mortality decreased by 44.5% between 1990 and 2017, from 531 956 (uncertainty interval (UI): 484 107 to 572 854) to 295 210 (284 493 to 306 187) deaths. Global age-standardised mortality rates decreased 57.4%, from 9.3 (8.5 to 10.0) in 1990 to 4.0 (3.8 to 4.1) per 100 000 per annum in 2017. Unintentional drowning-associated mortality was generally higher in children, males and in low-SDI to middle-SDI countries. China, India, Pakistan and Bangladesh accounted for 51.2% of all drowning deaths in 2017. Oceania was the region with the highest rate of age-standardised YLLs in 2017, with 45 434 (40 850 to 50 539) YLLs per 100 000 across both sexes. __Conclusions:__ There has been a decline in global drowning rates. This study shows that the decline was not consistent across countries. The results reinforce the need for continued and improved policy, prevention and research efforts, with a focus on low-and middle-income countries

    The Physics of the B Factories

    Get PDF

    Materials for advanced electric machines: an overview

    No full text
    Materials behavior, along with the machine design, controls the performance of the electric machine. Advanced electric machines are placing increased demands on materials behavior especially to achieve power density, efficiency, and endurance. For the Electric Ship, such advanced electric machines include actuators, motors, generators, certain energy storage systems, electric clutches and brakes, and specialized machines for weaponry. Small engineering refinements from practice are often inadequate for the advanced electric machine systems and the associated materials utilized in these machines to meet performance goals. A method for directing appropriate attention to materials requirements based on the machine performance goals is needed. This paper will present a method for prioritizing materials issues based on ten machine performance categories. As each advanced electric machine will present a unique set of requirements, the prioritization guides valuing of associated materials issues.Center for Electromechanic

    Marine subsidies produce cactus forests on desert islands

    No full text
    In island systems, nitrogen-rich seabird guano is a marine subsidy that can shape terrestrial plant communities. In zones of nutrient upwelling such as the Gulf of California, copious seabird guano is commonplace on bird islands. Several bird islands host regionally unique cactus forests, especially of the large columnar cactus, cardón (Pachycereus pringlei). We show that a chain of interactions across the land-sea interface yields an allochthonous input of nitrogen in the form of seabird guano, fueling the production of some of the densest cactus populations in the world. Fish, seabird, guano, soil, and cactus samples were taken from the representative seabird island of San Pedro Mártir for nitrogen stable isotope ratio measurements, which were compared to soil and cactus samples from other seabird and non-seabird Gulf islands and terrestrial ecosystems throughout the range of the cardón. Isla San Pedro Mártir δ15N values are distinctively high, ranging from fish + 17.7, seabird + 19.7, guano + 14.8, soil + 34.3 and cactus + 30.3 compared to average values across non-bird sites of + 13.0 (N = 213, S.D. = 3.7) for soil and + 9.8 (N = 212, S.D. = 3.4) for cactus. These δ15N values are among the highest ever reported for plants. Seabird island soil and cactus δ15N values were consistently significantly enriched relative to mainland and non-bird islands, a relationship expected due to the progressive volatilization of 14N rich ammonia from decomposing guano deposits. Our findings demonstrate that seabird-mediated marine nutrient deposits provide the source for solubilized nitrogen on desert islands, which stimulate terrestrial plant production in the cardón cactus beyond that seen in either mainland ecosystems or non-seabird islands. © 2022, The Author(s).Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

    Selective and graded recruitment of cat hamstring muscles with intrafascicular stimulation

    No full text
    The muscles of the hamstring group can produce different combinations of hip and knee torque. Thus, the ability to activate the different hamstring muscles selectively is of particular importance in eliciting functional movements such as stance and gait in a person with spinal cord injury.We investigated the ability of intrafascicular stimulation of the muscular branch of the sciatic nerve to recruit the feline hamstring muscles in a selective and graded fashion. A Utah Slanted Electrode Array, consisting of 100 penetrating microelectrodes, was implanted into the muscular branch of the sciatic nerve in six cats. Muscle twitches were evoked in the three compartments of biceps femoris (anterior, middle, and posterior), as well as semitendinosus and semimembranosus, using pulse-width modulated constant-voltage pulses. The resultant compound muscle action potentials were recorded using intramuscular fine-wire electrodes. 74% of the electrodes per implant were able to evoke a threshold response in these muscles, and these electrodes were evenly distributed among the instrumented muscles. Of the five muscles instrumented, on average 2.5 could be selectively activated to 90% of maximum EMG, and 3.5 could be selectively activated to 50% of maximum EMG. The muscles were recruited selectively with a mean stimulus dynamic range of 4.14 5.05 dB between threshold and either spillover to another muscle or a plateau in the response. This selective and graded activation afforded by intrafascicular stimulation of the muscular branch of the sciatic nerve suggests that it is a potentially useful stimulation paradigm for eliciting distinct forces in the hamstring muscle group in motor neuroprosthetic applications.</p

    Automated stimulus-response mapping of high-electrode-count neural implants

    No full text
    Over the past decade, research in the field of functional electrical stimulation (FES) has led to a new generation of high-electrode-count (HEC) devices that offer increasingly selective access to neural populations. Incorporation of these devices into research and clinical applications, however, has been hampered by the lack of hardware and software platforms capable of taking full advantage of them. In this paper, we present the first generation of a closed-loop FES platform built specifically for HEC neural interface devices. The platform was designed to support a wide range of stimulus-response mapping and feedback-based control routines. It includes a central control module, a 1100-channel stimulator, an array of biometric devices, and a 160-channel data recording module. To demonstrate the unique capabilities of this platform, two automated software routines for mapping stimulus-response properties of implanted HEC devices were implemented and tested. The first routine determines stimulation levels that produce perithreshold muscle activity, and the second generates recruitment curves (as measured by peak impulse response). Both routines were tested on 100-electrode Utah Slanted Electrode Arrays (USEAs) implanted in cat hindlimb nerves using joint torque or emg as muscle output metric. Mean time to map perithreshold stimulus level was 16.4 s for electrodes that evoked responses (n = 3200), and 3.6 s for electrodes that did not evoke responses (n = 1800). Mean time to locate recruitment curve asymptote for an electrode (n = 155) was 9.6 s , and each point in the recruitment curve required 0.87 s. These results demonstrate the utility of our FES platform by showing that it can be used to completely automate a typically time- and effort-intensive procedure associated with using HEC devices.</p

    The BaBar detector: Upgrades, operation and performance

    Get PDF
    Contains fulltext : 121729.pdf (preprint version ) (Open Access
    corecore