7,055 research outputs found
Biodegradation Behavior of Ozonated Natural Organic Matter in Sand Filters
Aujourd'hui, il est démontré que les traitements biologiques utilisés pour le traitement de l'eau potable sont des méthodes efficaces pour la réduction de la matière organique de l'eau, des sous-produits de la désinfection, ainsi que pour le contrôle de la croissance bactérienne dans les réseaux.Quelques études récentes ont tenté de modéliser ce qui se passait sur les filtres biologiques utilisés pour le traitement de l'eau potable. Les modèles de biofilms développés pour les eaux usées sont souvent utilisés pour l'eau potable. Contrairement au biofilm des eaux usées, épais et dense, celui de l'eau potable est dispersè en fraction dans le milieu du filtre ainsi que sur sa pami. Le biofilm est donc très dispersé et les paramètres importants de modélisation du biofilm en eau usée (densité, épaisseur) ne sont pas appropriés pour l'estimation du biofilm dans les filtres d'eau potable.La matière organique est constituée d'un ensemble complexe de composés organiques. Quelques-uns ne sont pas facilement biodégradables, d'autres le sont facilement et une autre fraction est récalcitrante. Dans ces conditions, un modèle utilisant un seul substrat pour représenter la cinétique de biodégradation n'est pas approprié. WANG et SUMMERS (1994) ont récemment développé un modèle mathématique utilisant plusieurs substrats pour décrire la réduction de la matière organique de l'eau dans les filtres biologiques. Le modèle suppose que la filtration biologique est composée de deux étapes : un transfert massique exteme suivi de l'utilisation du substrat à la surface du filtre. Dans ce modèle, la matière organique est divisée en trois portions: des composés facilement ou lentement biodégradables et récalcitrants. Des vitesses différentes de réaction sont utilisées pour chaque fraction. Les résultats démontrent que la diminution de la concentration de la matière organique est souvent limitée parle taux d'utilisation des substrats, et non pas par la vitesse du transfert exteme de la matière.Les objectifs de cette recherche sont d'identifier les éléments de la matière organique ainsi que les composés lentement ou rapidement biodégradables et de suivre l'évolution de ces composés dans les filtres biologiques.Une fois traitée par ozonisation, la matière organique est utilisée comme substrat dans cette recherche. La matière organique a été isolée par concentration sur résine échangeuse d'ions d'une eau souterraine prélevée en Allemagne. Le taux de traitements en ozone a été de 0,35 mg O3 par mg de carbone organique dissous (COD). Un sable bioacclimaté a été utilisé comme milieu filtrant et comme source de biomasse. Avant chaque expérience, il a été mélangé pour avoir une répartition homogène de la biomasse dans le filtre, La quantité de substrats était mesurée par les analyses du COD, du carbone organique dissous biodégradable (CODB), du carbone organique assimilable (COA), des aldéhydes et d'acides cétoniques. Les résultats, exprimés en terme du temps de contact théorique, démontrent que la vitesse de filtration dans le filtre (dans des proportions de 1,5 à 15 m/h) n'a pas d'influence sur la réduction des substrats. Le facteur limitant pour l'élimination du carbone organique par filtration est donc l'utilisation du substrat et non par le transfert externe de matière.Dans cette recherche, la fraction de la matière organique est appelée « rapidement biodégradable » si elle est éliminée dans les trois premières minutes du temps de contact. Elle constitue 15 ib du COD. La fraction du CODB de l'eau traitée par ozonisation représente environ 40 à 45 % du COD.Presqu'un tiers du CODB est rapidement biodégradé. Les résultats démontrent que 90 % du COA est utilisé par le Spirillum sp . NOX (COA-NOX), et que presque tout le COA est rapidement biodégradé et s'élimine par biofiltration en une minute de temps de contact. Le glyoxal et le méthyl glyoxal sont totalement éliminés après deux minutes de temps de contact. Par contre, seulement 60 % du formaldéhyde est éliminé dans les deux premières minutes de temps de contact et l'augmentation du temps de contact n'engendre pas une élimination supplémentaire. En outre, on n'observe pas de réduction significative de l'acétaldéhyde. Les résultats démontrent que les acides cétoniques sont rapidement et fortement dégradés. Plus de 90 % d'acide glyoxalique et d'acide pyruvique sont éliminés dans la première minute de temps de contact.Natural organic matter (NOM) in drinking water is a complex mixture of organic compounds. Some of the compounds are not biodegradable, while others are quickly biodegradable and a third group is more resistant to biodegradation. To have a better understanding of the biofiltration process in drinking water treatment, it is important to identify the elements of the quickly and slowly biodegradable NOM and to characterize the biodegradation rate of each element. In this study, an ozonated NOM solution was used as the substrate. The NOM was isolated from a groundwater in Germany using ion-exchange resins. The ozone dose was 0.35 mg O3/mg DOC (dissolved organic carbon). Previously bioacclimated sand was used as filter media and biomass source and was homogeneously distributed in the filter prior to each run. The substrate removal was evaluated by DOC, biodegradable DOC (BDOC), assimilable organic carbon (AOC), aldehyde and ketoacid analyses. When expressed in terms of the empty bed contact time (EBCT), the results showed that filter velocity in the range of 1.5 to 15 m/hr had no impact on substrate removal. This implies that substrate utilization, not external mass transfer, is the rate limiting step for substrate removal in drinking water biofilters. In this study, compounds or NOM fractions are termed quickly biodegradable if they are removed in the first three minutes of EBCT. 15% of the DOC was removed by the biofilter within three minutes of EBCT and was termed the quickly biodegradable fraction. The BDOC fraction of the ozonated solution was determined to be 40 to 45% of the DOC. In terms of BDOC, about one third of the total BDOC was quickly biodegradable. The AOC results show that about 90% of the total AOC was utilized by Spirillum sp. NOX (AOC-NOX). Most of the AOC was quickly biodegradable and was removed within one minute of EBCT. For aldehydes, glyoxal and methyl glyoxal were removed to below the detection limit after two minutes of EBCT. However, only 60% of formaldehyde removal was achieved in the first two minutes of EBCT, and no additional removal was achieved with increasing EBCT. Additionally, no significant removal of acetaldehyde was observed. The results of ketoacids show that their utilization rates were very high. More than 90% of glyoxylic acid and pyruvic acid were removed within one minute of EBCT
Disappearance of plasmaspheric hiss following interplanetary shock
Abstract Plasmaspheric hiss is one of the important plasma waves controlling radiation belt dynamics. Its spatiotemporal distribution and generation mechanism are presently the object of active research. We here give the first report on the shock-induced disappearance of plasmaspheric hiss observed by the Van Allen Probes on 8 October 2013. This special event exhibits the dramatic variability of plasmaspheric hiss and provides a good opportunity to test its generation mechanisms. The origination of plasmaspheric hiss from plasmatrough chorus is suggested to be an appropriate prerequisite to explain this event. The shock increased the suprathermal electron fluxes, and then the enhanced Landau damping promptly prevented chorus waves from entering the plasmasphere. Subsequently, the shrinking magnetopause removed the source electrons for chorus, contributing significantly to the several-hours-long disappearance of plasmaspheric hiss
The alpha 7 nicotinic receptor agonist PHA-543613 hydrochloride inhibits <i>Porphyromonas gingivalis</i>-induced expression of interleukin-8 by oral keratinocytes
Objective:
The alpha 7 nicotinic receptor (α7nAChR) is expressed by oral keratinocytes. α7nAChR activation mediates anti-inflammatory responses. The objective of this study was to determine if α7nAChR activation inhibited pathogen-induced interleukin-8 (IL-8) expression by oral keratinocytes.<p></p>
Materials and methods:
Periodontal tissue expression of α7nAChR was determined by real-time PCR. OKF6/TERT-2 oral keratinocytes were exposed to <i>Porphyromonas gingivalis</i> in the presence and absence of a α7nAChR agonist (PHA-543613 hydrochloride) alone or after pre-exposure to a specific α7nAChR antagonist (α-bungarotoxin). Interleukin-8 (IL-8) expression was measured by ELISA and real-time PCR. Phosphorylation of the NF-κB p65 subunit was determined using an NF-κB p65 profiler assay and STAT-3 activation by STAT-3 in-cell ELISA. The release of ACh from oral keratinocytes in response to <i>P. gingivalis</i> lipopolysaccharide was determined using a GeneBLAzer M3 CHO-K1-blacell reporter assay.<p></p>
Results:
Expression of α7nAChR mRNA was elevated in diseased periodontal tissue. PHA-543613 hydrochloride inhibited <i>P. Gingivalis</i>-induced expression of IL-8 at the transcriptional level. This effect was abolished when cells were pre-exposed to a specific α7nAChR antagonist, α-bungarotoxin. PHA-543613 hydrochloride downregulated NF-κB signalling through reduced phosphorylation of the NF-κB p65-subunit. In addition, PHA-543613 hydrochloride promoted STAT-3 signalling by maintenance of phosphorylation. Furthermore, oral keratinocytes upregulated ACh release in response to <i>P. Gingivalis</i> lipopolysaccharide.<p></p>
Conclusion:
These data suggest that α7nAChR plays a role in regulating the innate immune responses of oral keratinocytes.<p></p>
MICE: The muon ionization cooling experiment. Step I: First measurement of emittance with particle physics detectors
Copyright @ 2011 APSThe Muon Ionization Cooling Experiment (MICE) is a strategic R&D project intended to demonstrate the only practical solution to providing high brilliance beams necessary for a neutrino factory or muon collider. MICE is under development at the Rutherford Appleton Laboratory (RAL) in the United Kingdom. It comprises a dedicated beamline to generate a range of input muon emittances and momenta, with time-of-flight and Cherenkov detectors to ensure a pure muon beam. The emittance of the incoming beam will be measured in the upstream magnetic spectrometer with a scintillating fiber tracker. A cooling cell will then follow, alternating energy loss in Liquid Hydrogen (LH2) absorbers to RF cavity acceleration. A second spectrometer, identical to the first, and a second muon identification system will measure the outgoing emittance. In the 2010 run at RAL the muon beamline and most detectors were fully commissioned and a first measurement of the emittance of the muon beam with particle physics (time-of-flight) detectors was performed. The analysis of these data was recently completed and is discussed in this paper. Future steps for MICE, where beam emittance and emittance reduction (cooling) are to be measured with greater accuracy, are also presented.This work was supported by NSF grant PHY-0842798
Status of Muon Collider Research and Development and Future Plans
The status of the research on muon colliders is discussed and plans are
outlined for future theoretical and experimental studies. Besides continued
work on the parameters of a 3-4 and 0.5 TeV center-of-mass (CoM) energy
collider, many studies are now concentrating on a machine near 0.1 TeV (CoM)
that could be a factory for the s-channel production of Higgs particles. We
discuss the research on the various components in such muon colliders, starting
from the proton accelerator needed to generate pions from a heavy-Z target and
proceeding through the phase rotation and decay ()
channel, muon cooling, acceleration, storage in a collider ring and the
collider detector. We also present theoretical and experimental R & D plans for
the next several years that should lead to a better understanding of the design
and feasibility issues for all of the components. This report is an update of
the progress on the R & D since the Feasibility Study of Muon Colliders
presented at the Snowmass'96 Workshop [R. B. Palmer, A. Sessler and A.
Tollestrup, Proceedings of the 1996 DPF/DPB Summer Study on High-Energy Physics
(Stanford Linear Accelerator Center, Menlo Park, CA, 1997)].Comment: 95 pages, 75 figures. Submitted to Physical Review Special Topics,
Accelerators and Beam
First Observation of CP Violation in B0->D(*)CP h0 Decays by a Combined Time-Dependent Analysis of BaBar and Belle Data
We report a measurement of the time-dependent CP asymmetry of B0->D(*)CP h0
decays, where the light neutral hadron h0 is a pi0, eta or omega meson, and the
neutral D meson is reconstructed in the CP eigenstates K+ K-, K0S pi0 or K0S
omega. The measurement is performed combining the final data samples collected
at the Y(4S) resonance by the BaBar and Belle experiments at the
asymmetric-energy B factories PEP-II at SLAC and KEKB at KEK, respectively. The
data samples contain ( 471 +/- 3 ) x 10^6 BB pairs recorded by the BaBar
detector and ( 772 +/- 11 ) x 10^6, BB pairs recorded by the Belle detector. We
measure the CP asymmetry parameters -eta_f S = +0.66 +/- 0.10 (stat.) +/- 0.06
(syst.) and C = -0.02 +/- 0.07 (stat.) +/- 0.03 (syst.). These results
correspond to the first observation of CP violation in B0->D(*)CP h0 decays.
The hypothesis of no mixing-induced CP violation is excluded in these decays at
the level of 5.4 standard deviations.Comment: 9 pages, 2 figures, submitted to Physical Review Letter
Measurement of the quasi-elastic axial vector mass in neutrino-oxygen interactions
The weak nucleon axial-vector form factor for quasi-elastic interactions is
determined using neutrino interaction data from the K2K Scintillating Fiber
detector in the neutrino beam at KEK. More than 12,000 events are analyzed, of
which half are charged-current quasi-elastic interactions nu-mu n to mu- p
occurring primarily in oxygen nuclei. We use a relativistic Fermi gas model for
oxygen and assume the form factor is approximately a dipole with one parameter,
the axial vector mass M_A, and fit to the shape of the distribution of the
square of the momentum transfer from the nucleon to the nucleus. Our best fit
result for M_A = 1.20 \pm 0.12 GeV. Furthermore, this analysis includes updated
vector form factors from recent electron scattering experiments and a
discussion of the effects of the nucleon momentum on the shape of the fitted
distributions.Comment: 14 pages, 10 figures, 6 table
A Study of Time-Dependent CP-Violating Asymmetries and Flavor Oscillations in Neutral B Decays at the Upsilon(4S)
We present a measurement of time-dependent CP-violating asymmetries in
neutral B meson decays collected with the BABAR detector at the PEP-II
asymmetric-energy B Factory at the Stanford Linear Accelerator Center. The data
sample consists of 29.7 recorded at the
resonance and 3.9 off-resonance. One of the neutral B mesons,
which are produced in pairs at the , is fully reconstructed in
the CP decay modes , , , () and , or in flavor-eigenstate
modes involving and (). The flavor of the other neutral B meson is tagged at the time of
its decay, mainly with the charge of identified leptons and kaons. The proper
time elapsed between the decays is determined by measuring the distance between
the decay vertices. A maximum-likelihood fit to this flavor eigenstate sample
finds . The value of the asymmetry amplitude is determined from
a simultaneous maximum-likelihood fit to the time-difference distribution of
the flavor-eigenstate sample and about 642 tagged decays in the
CP-eigenstate modes. We find , demonstrating that CP violation exists in the neutral B meson
system. (abridged)Comment: 58 pages, 35 figures, submitted to Physical Review
Recommended from our members
Precise Measurement of the e+ e- --> pi+ pi- (gamma) Cross Section with the Initial-State Radiation Method at BABAR
A precise measurement of the cross section of the process
from threshold to an energy of 3GeV is obtained
with the initial-state radiation (ISR) method using 232fb of data
collected with the BaBar detector at center-of-mass energies near
10.6GeV. The ISR luminosity is determined from a study of the leptonic process
, which is found to agree with the
next-to-leading-order QED prediction to within 1.1%. The cross section for the
process is obtained with a systematic uncertainty
of 0.5% in the dominant resonance region. The leading-order hadronic
contribution to the muon magnetic anomaly calculated using the measured
cross section from threshold to 1.8GeV is .Comment: 58 pages, 56 figures, to be submitted to Phys. Rev.
Measurement of the Branching Fraction for B- --> D0 K*-
We present a measurement of the branching fraction for the decay B- --> D0
K*- using a sample of approximately 86 million BBbar pairs collected by the
BaBar detector from e+e- collisions near the Y(4S) resonance. The D0 is
detected through its decays to K- pi+, K- pi+ pi0 and K- pi+ pi- pi+, and the
K*- through its decay to K0S pi-. We measure the branching fraction to be
B.F.(B- --> D0 K*-)= (6.3 +/- 0.7(stat.) +/- 0.5(syst.)) x 10^{-4}.Comment: 7 pages, 1 postscript figure, submitted to Phys. Rev. D (Rapid
Communications
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