417 research outputs found
Challenges and Countermeasures of Teachers’ Professional Development from the Perspective of Globalization
Under the influence of globalization, the intensification of international competition is in the final analysis the competition of education and talents. Teachers are the main body of teaching activities. Teachers’ professionalization is an important symbol to measure a country’s educational level. At present, the professional development of teachers in China is facing enormous challenges. In terms of concept, system and the allocation and utilization of educational resources, there are great problems. In order to meet the needs of teachers’ professional development in the perspective of globalization, the new era should promote the upgrading of teachers’ professional level from the aspects of renewal of ideas, improvement of system guarantee system, diversified development and integration and distribution of resources
Neutron Energy Spectrum Measurements with a Compact Liquid Scintillation Detector on EAST
A neutron detector based on EJ301 liquid scintillator has been employed at
EAST to measure the neutron energy spectrum for D-D fusion plasma. The detector
was carefully characterized in different quasi-monoenergetic neutron fields
generated by a 4.5 MV Van de Graaff accelerator. In recent experimental
campaigns, due to the low neutron yield at EAST, a new shielding device was
designed and located as close as possible to the tokamak to enhance the count
rate of the spectrometer. The fluence of neutrons and gamma-rays was measured
with the liquid neutron spectrometer and was consistent with 3He proportional
counter and NaI (Tl) gamma-ray spectrometer measurements. Plasma ion
temperature values were deduced from the neutron spectrum in discharges with
lower hybrid wave injection and ion cyclotron resonance heating. Scattered
neutron spectra were simulated by the Monte Carlo transport Code, and they were
well verified by the pulse height measurements at low energies.Comment: 19 pages,10 figures, 1 tabl
Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion
AbstractThousands of genes have been well demonstrated to play important roles in cancer progression. As genes do not function in isolation, they can be grouped into “networks” based on their interactions. In this study, we discover a network regulating Claudin-4 in gastric cancer. We observe that Claudin-4 is up-regulated in gastric cancer and is associated with poor prognosis. Claudin-4 reinforce proliferation, invasion, and EMT in AGS, HGC-27, and SGC-7901 cells, which could be reversed by miR-596 and miR-3620-3p. In addition, lncRNA-KRTAP5-AS1 and lncRNA-TUBB2A could act as competing endogenous RNAs to affect the function of Claudin-4. Our results suggest that non-coding RNAs play important roles in the regulatory network of Claudin-4. As such, non-coding RNAs should be considered as potential biomarkers and therapeutic targets against gastric cancer.</jats:p
Which is better for gastric cancer patients, perioperative or adjuvant chemotherapy: a meta-analysis
meta-analysis of chemotherapy adverse effects. (A) Nausea and vomit, (B) gastrointestinal problem, (C) liver toxicity, (D) neurologic effects, (E) leukopenia, (F) thrombocytopenia, (G) neutropenia. (TIF 507Ă‚Â kb
Sodium-Related Adaptations to Drought: New Insights From the Xerophyte Plant Zygophyllum xanthoxylum
Understanding the unusual physiological mechanisms that enable drought tolerance in xerophytes will be of considerable benefit because of the potential to identify novel and key genetic elements for future crop improvements. These plants are interesting because they are well-adapted for life in arid zones; Zygophyllum xanthoxylum, for example, is a typical xerophytic shrub that inhabits central Asian deserts, accumulating substantial levels of sodium (Na+) in its succulent leaves while growing in soils that contain very low levels of this ion. The physiological importance of this unusual trait to drought adaptations remains poorly understood, however. Thus, 2-week-old Z. xanthoxylum plants were treated with 50 mM NaCl (Na) for 7 days in this study in order to investigate their drought tolerance, leaf osmotic potential (Ψs) related parameters, anatomical characteristics, and transpiration traits. The results demonstrated that NaCl treatment significantly enhanced both the survivability and durability of Z. xanthoxylum plants under extreme drought conditions. The bulk of the Na+ ions encapsulated in plants was overwhelmingly allocated to leaves rather than roots or stems under drought conditions; thus, compared to the control, significantly more Na+ compared to other solutes such as K+, Ca2+, Cl-, sugars, and proline accumulated in the leaves of NaCl-treated plants and led to a marked decrease (31%) in leaf Ψs. In addition, the accumulation of Na+ ions also resulted in mesophyll cell enlargement and leaf succulence, enabling the additional storage of water; Na+ ions also reduced the rate of water loss by decreasing stomatal density and down-regulating stomatal aperture size. The results of this study demonstrate that Z. xanthoxylum has evolved a notable ability to utilize Na+ ions to lower Ψs, swell its leaves, and decrease stomatal aperture sizes, in order to enable the additional uptake and storage of water and mitigate losses. These distinctive drought adaption characteristics mean that the xerophytic plant Z. xanthoxylum presents a fascinating case study for the potential identification of important and novel genetic elements that could improve crops. This report provides insights on the eco-physiological role of sodium accumulation in xerophytes adapted to extremely arid habitats
Experimental observation of topological Fermi arcs in type-II Weyl semimetal MoTe2
Weyl semimetal is a new quantum state of matter [1-12] hosting the condensed
matter physics counterpart of relativisticWeyl fermion [13] originally
introduced in high energy physics. The Weyl semimetal realized in the TaAs
class features multiple Fermi arcs arising from topological surface states [10,
11, 14-16] and exhibits novel quantum phenomena, e.g., chiral anomaly induced
negative mag-netoresistance [17-19] and possibly emergent supersymmetry [20].
Recently it was proposed theoretically that a new type (type-II) of Weyl
fermion [21], which does not have counterpart in high energy physics due to the
breaking of Lorentz invariance, can emerge as topologically-protected touching
between electron and hole pockets. Here, we report direct spectroscopic
evidence of topological Fermi arcs in the predicted type-II Weyl semimetal
MoTe2 [22-24]. The topological surface states are confirmed by directly
observing the surface states using bulk-and surface-sensitive angle-resolved
photoemission spectroscopy (ARPES), and the quasi-particle interference (QPI)
pattern between the two putative Fermi arcs in scanning tunneling microscopy
(STM). Our work establishes MoTe2 as the first experimental realization of
type-II Weyl semimetal, and opens up new opportunities for probing novel
phenomena such as exotic magneto-transport [21] in type-II Weyl semimetals.Comment: submitted on 01/29/2016. Nature Physics, in press. Spectroscopic
evidence of the Fermi arcs from two complementary surface sensitive probes -
ARPES and STS. A comparison of the calculated band structure for T_d and 1T'
phase to identify the topological Fermi arcs in the T_d phase is also
included in the supplementary informatio
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