Plan de mejora en el proceso de Evaluación de Desempeño de la ips pharmasan

Cuando la Evaluación del desempeño se constituye como el eje central del funcionamiento empresarial, conviene que, todos y cada uno de los integrantes de organización, conozcan y se involucren con cada uno de los pasos de que se compone este, de ahí que, se presentan los resultados de la indagación que se hiciera en la IPS PHARMSAN de la ciudad de Bucaramanga y que buscó diseñar un plan de mejora del desempeño laboral como componente fundamental del desarrollo administrativo de la empresa. Se aplicó una metodología cualitativa y con enfoque socio crítico, aplicado a una población de usuarios seleccionados de manera aleatoria y a los cuales se les aplicó una encuesta virtual con la cual se sistematizaron los resultados presentados en este informe.When the Performance Evaluation is constituted as the central axis of the business operation, it is convenient that each and every one of the members of the organization, know and get involved with each of the steps that make up this, hence, they are presented the results of the investigation that was made in the IPS PHARMSAN of the city of Bucaramanga and that sought to Design a model for the improvement of work performance as a fundamental component of the administrative development of the company. A qualitative methodology with a socio-critical approach was applied, applied to a population of randomly selected users and to whom a virtual survey was applied with which the results presented in this report were systematized

Efecto cardioprotector de los inhibidores de sglt2 y agonistas del receptor de glp-1

Methodology: a narrative review was carried out through various databases from january 2015 to january 2022; the search and selection of articles was carried out in journals indexed in english. the following keywords were used: cardioprotective, sglt2 inhibitors, glp-1 receptor agonists. results: sglt2i reduce glycosylated hemoglobin between 0.5% and 1.0%, showing favorable effects on body weight, blood pressure, lipid profile, arterial stiffness and endothelial function. glp-1 analogs significantly reduce blood pressure values. the physiological mechanisms by which regulation is reached are still not entirely clear. various mechanisms have been proposed, among which we find the direct activation of the glp-1 receptor in the arteries and the renal system, including an improvement in endothelial function, as well as a vasodilator and natriuretic effect. conclusions: this review offers updated and detailed information on the cardioprotective effects that are provided by the use of sglt2 inhibitors and glp-1 receptor agonists in diabetic patients, especially in those with risk factors for developing cardiovascular diseases.Metodología: Se realizó una revisión narrativa a través de diversas bases de datos de Enero de 2015 a Enero de 2022; la búsqueda y selección de artículos fue llevada a cabo en revistas indexadas en idioma inglés. Se utilizaron como palabras clave: Cardioprotector, inhibidores de SGLT2, agonistas del receptor de GLP-1. Resultados: Los SGLT2i reducen la hemoglobina glicosilada entre un 0,5 % y un 1,0 % demostrando efectos favorables sobre el peso corporal, la presión arterial, el perfil lipídico, la rigidez arterial y la función endotelial. Los análogos del GLP-1 reducen significativamente los valores de la Presión arterial. Los mecanismos fisiológicos por los cuales se llega a una regulación aun no son del todo claras. Se han planteado diversos mecanismos, dentro de los cuales encontramos la activación directa del receptor del GLP-1 en las arterias y el sistema renal, incluida una mejora de la función endotelial, así como un efecto vasodilatador y natriurético. Conclusiones: La presente revisión ofrece información actualizada y detallada sobre los efectos cardioprotectores que son brindados por el uso de los inhibidores de SGLT2 y agonistas del receptor de GLP-1 en pacientes diabéticos, especialmente en aquellos con factores de riesgo de desarrollar enfermedades cardiovasculares

The Caldera. No. 24

El poder extraordinario que tiene la literatura, en la vida de un ser humano, es incalculable; no sólo es abrir un libro y pasar los ojos por las páginas; ¡No! Es dejarse atrapar, dejarse llevar por mundos y contextos distintos, diversos, pletóricos de vivencias humanas que nos hacen únicos e irrepetibles. Cada vez que abrimos un libro y nos damos el permiso de leerlo, nos volvemos mejores seres humanos, porque comprendemos más al otro, o por lo menos, tratamos de reconocer cómo vivían, cómo pensaban, cómo actuaban, en otras épocas, incluyendo la nuestra. Con la lectura, podemos entender por qué los seres humanos son como son, potenciamos la empatía y fortalecemos la conciencia moral, entre algunas ventajas que tiene este proceso que nos acompaña a lo largo de toda la vida. Este año, en la mejor Feria del Libro del Oriente Colombiano, ULIBRO 2021, que se realiza del 30 de agosto, al 4 de septiembre, estamos invitados a participar en conversatorios, talleres, encuentros con autores, entre otras actividades propuestas, de manera presencial y virtual, para seguir fortaleciendo nuestro proyecto de vida; también, estamos invitados a dejarnos contagiar de la lectura, de la escritura, de la oralidad, a partir de “Las historias asombrosas”, que se van a tomar los diferentes espacios propuestos.1. Experiencias Internacionales…5 2. Homenaje al Dr. Alfonso Gómez Gómez; Por Samir Rodríguez Sarmiento…12 3. Nuestro Preescolar; Por Pilar Rocío Silva, Clara María Hassen y Laura Melissa Ayala…16 4. Maestros Caldistas; Por Gisela Afanador Díaz y Elena Mireya Brijaldo…20 5. Reloj Solar…24 6. La Cuna de Excélsior. VIII Concurso de Lectura en Voz Alta…29 7. VIII Concurso Intercolegiado Departamental de Oratoria...35 8. Homenaje a Augusto Monterroso; Por comunidad caldista...49 9. Expresiones Caldistas…52 10. Galería de Imágenes…86 11. Nuestros Maestros…92The extraordinary power that literature has, in the life of a human being, is incalculable; It is not just opening a book and running your eyes through the pages; No! It is to let yourself be trapped, to let yourself be carried away by different, diverse worlds and contexts, full of human experiences that make us unique and unrepeatable. Every time we open a book and give ourselves permission to read it, we become better human beings, because we understand others more, or at least, we try to recognize how they lived, how they thought, how they acted, in other times, including ours. . With reading, we can understand why human beings are the way they are, we enhance empathy and strengthen moral conscience, among some advantages that this process has that accompanies us throughout our lives. This year, in the best Book Fair of the Colombian East, ULIBRO 2021, which takes place from August 30 to September 4, we are invited to participate in talks, workshops, meetings with authors, among other proposed activities, in person and virtual, to continue strengthening our life project; Also, we are invited to let ourselves be infected with reading, writing, orality, starting from "The amazing stories", which are going to take the different spaces proposed

Stable graphene oxide-gold nanoparticle platforms for biosensing applications

Graphene oxide-gold nanoparticle (AuNPs@GO) hybrids were fabricated in water dispersions of graphene oxide (GO) and Au precursor completely free of stabilizing agents by UV-light irradiation. Gold nanoparticle (AuNP) nucleation, growth, and stabilization mechanisms at the surface of GO are discussed on the basis of UV-Vis, Raman, IR, and X-Ray photo-spectroscopy studies. The analyses of AuNPs@GO hybrids by transmission electron microscopy (TEM), thermogravimetric (TGA) and electrochemical tests show that they exhibit outstanding chemical, thermal and electrochemical stabilities. Thus, AuNPs@GO biosensing platforms were fabricated for surface enhanced Raman spectroscopy (SERS) detection of crystal violet (CV), a SERS standard molecule, and in a different set of experiments, for flavin adenine dinucleotide (FAD), a flavoprotein coenzyme that plays an important role in many oxidoreductase and reversible redox conversions in biochemical reactions. AuNPs@GO hybrids synthesized by using UV light irradiation show exceptional stability and high intensification of the Raman signals showing that they have high potential for use as biomedical probes for the detection, monitoring, and diagnosis of medical diseases.Fil: Hernández Sánchez, Dania. Universidad Autónoma de San Luis Potosí; México. Graphenemex S.A.; MéxicoFil: Villabona Leal, Giovanny. Universidad Autónoma de San Luis Potosí; MéxicoFil: Saucedo Orozco, Izcoatl. Universidad Autónoma de San Luis Potosí; MéxicoFil: Bracamonte, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; ArgentinaFil: Pérez, Eliás. Universidad Autónoma de San Luis Potosí; MéxicoFil: Bittencourt, Carla. University of Mons; BélgicaFil: Quintana, Mildred. Universidad Autónoma de San Luis Potosí; Méxic

Antibacterial Additive for Polystyrene Based on Silver Nanoparticles Supported on Titanium Dioxide

Silver nanoparticles supported on titanium dioxide nanoparticles (Ag/TiO2) were incorporated and evaluated as antibacterial additive for polystyrene materials. These particles were synthesized using a deposition-precipitation method by adding silver nitrate as metallic precursor, sodium hydroxide as reducing agent, and commercial TiO2 (P25) as support. Rectangular pieces of polystyrene (PS) containing 100, 300, 500, and 700 ppm (wt.%) of the additive were made using an extrusion-injection molding process, and they were evaluated for their antibacterial properties against Escherichia coli using the Pour Plate method. Particles were distributed on the PS surface, and PS pieces presented a good antibacterial efficiency at 100, 300, and 500 ppm and decreased for 700 ppm due to an additive agglomeration on the PS surface. These results validate the antibacterial properties of Ag/TiO2, determine a concentration limit at which the additive is well distributed on the PS surface, and assess the importance of Ag in this system