2,528 research outputs found

    Quantifying image distortion based on Gabor filter bank and multiple regression analysis

    Get PDF
    Image quality assessment is indispensable for image-based applications. The approaches towards image quality assessment fall into two main categories: subjective and objective methods. Subjective assessment has been widely used. However, careful subjective assessments are experimentally difficult and lengthy, and the results obtained may vary depending on the test conditions. On the other hand, objective image quality assessment would not only alleviate the difficulties described above but would also help to expand the application field. Therefore, several works have been developed for quantifying the distortion presented on a image achieving goodness of fit between subjective and objective scores up to 92%. Nevertheless, current methodologies are designed assuming that the nature of the distortion is known. Generally, this is a limiting assumption for practical applications, since in a majority of cases the distortions in the image are unknown. Therefore, we believe that the current methods of image quality assessment should be adapted in order to identify and quantify the distortion of images at the same time. That combination can improve processes such as enhancement, restoration, compression, transmission, among others. We present an approach based on the power of the experimental design and the joint localization of the Gabor filters for studying the influence of the spatial/frequencies on image quality assessment. Therefore, we achieve a correct identification and quantification of the distortion affecting images. This method provides accurate scores and differentiability between distortions

    Disentangling the complexity of the rumen microbial diversity through fractionation using a sucrose density gradient

    Get PDF
    The ruminal microbial community is an important element in health, nutrition, livestock productivity, and climate impact. Despite the historic and current efforts to characterize this microbial diversity, many of its members remain unidentified, making it challenging to associate microbial groups with functions. Here we present a low-cost methodology for rumen sample treatment that separates the microbial community based on cell size, allowing for the identification of subtle compositional changes. In brief, the sample is centrifuged through a series of sucrose density gradients, and cells migrate to their corresponding density fraction. From each fraction, DNA is extracted an

    La fotografía gastronómica y la identidad de marca en el consumidor de un restaurante gourmet, Trujillo-2021

    Get PDF
    La presente investigación tuvo como objetivo identificar la relación existente entre el uso de la fotografía gastronómica y la formación de identidad de marca entre los consumidores de un restaurante gourmet de la ciudad de Trujillo. Para ello, los autores del trabajo se basaron en un enfoque netamente cuantitativo para analizar ambas variables, de tipo no experimental, con un diseño correlacional. En el estudio se aplicaron como instrumentos una guía de observación a las publicaciones en sus diversas plataformas digitales y se aplicó una encuesta utilizando la escala de Likert a una muestra por conveniencia, conformada por cien personas a quienes se les formuló preguntas, junto con una tabla de observación con diez muestras. Para la aprobación de las herramientas ejecutadas, se utilizó la matriz de validación de personas experimentadas y, por otro lado, el cálculo de Alfa de Cronbach que permita indicar la fiabilidad de la encuesta. Los resultados revelaron que ambas variables poseen una correlación significativa en el segmento y rubro al que se encuentra direccionada la investigación, siendo relevante el uso de fotografía gastronómica en el posicionamiento del restaurante gourmet.The objetctive of this research was to identify the relationship between the use of gastronomic photography and the formation of brand identity among consumers of a gourmet restaurant in the city of Trujillo. For this, the authors of the work used a purely quantitative approach to analyze both variables of a non-experimental type, with a correlational design. In the study, an observation guide was applied as instruments to the publications on its various digital platforms and a survey was applied using the Likert scale to a convenience sample, made up of one hundred people who were asked questions, along with a table observation with ten samples. For the approval of the executed tools, the validation matrix of experienced people was used and, on the other hand, the calculation of Cronbach's Alpha that allows indicating the reliability of the survey. The results revealed that both variables have a significant correlation in the segment and area to which the research is directed, the use of gastronomic photography being relevant in the positioning of the gourmet restaurant

    Volume-assured pressure support mode plus pirfenidone as resuscitation therapy in patients with exacerbation of idiopathic pulmonary fibrosis

    Get PDF
    Introduction: Treatment among advanced stage idiopathic pulmonary fibrosis is quite challenging, especially considering that no major evidence has been released about it. This case report demonstrates and discusses the benefit of non-invasive mechanical ventilation in volume-assured pressure support (AVAPS) mode plus pirfenidone based on the relief of a patient’s symptoms in combination with high-resolution computed tomography (HRCT) evidence.Material and methods: An 83-year-old female patient with multiple hospital admissions within a  six-month period initially presented with cardiac symptoms which were later attributed to a possible exacerbation of her primary diagnosis, idiopathic pulmonary fibrosis.Conclusion: The addition of non-invasive mechanical ventilation in AVAPS mode plus pirfenidone can improve the survival rates even in patients with current exacerbations of acute respiratory failure due to idiopathic pulmonary fibrosis

    Game Theory-Based Cooperation for Underwater Acoustic Sensor Networks: Taxonomy, Review, Research Challenges and Directions.

    Get PDF
    Exploring and monitoring the underwater world using underwater sensors is drawing a lot of attention these days. In this field cooperation between acoustic sensor nodes has been a critical problem due to the challenging features such as acoustic channel failure (sound signal), long propagation delay of acoustic signal, limited bandwidth and loss of connectivity. There are several proposed methods to improve cooperation between the nodes by incorporating information/game theory in the node's cooperation. However, there is a need to classify the existing works and demonstrate their performance in addressing the cooperation issue. In this paper, we have conducted a review to investigate various factors affecting cooperation in underwater acoustic sensor networks. We study various cooperation techniques used for underwater acoustic sensor networks from different perspectives, with a concentration on communication reliability, energy consumption, and security and present a taxonomy for underwater cooperation. Moreover, we further review how the game theory can be applied to make the nodes cooperate with each other. We further analyze different cooperative game methods, where their performance on different metrics is compared. Finally, open issues and future research direction in underwater acoustic sensor networks are highlighted

    Establishment of triple-negative breast cancer cells based on BMI: A novel model in the correlation between obesity and breast cancer

    Get PDF
    IntroductionObesity has been associated with an increased risk of biologically aggressive variants in breast cancer. Women with obesity often have tumors diagnosed at later stages of the disease, associated with a poorer prognosis and a different response to treatment. Human cell lines have been derived from specific subtypes of breast cancer and have served to define the cell physiology of corresponding breast cancer subtypes. However, there are no current cell lines for breast cancer specifically derived from patients with different BMIs. The availability of those breast cancer cell lines should allow to describe and unravel functional alterations linked to these comorbidities. MethodsCell cultures were established from tumor explants. Once generated, the triple negative subtype in a patient with obesity and a patient with a normal BMI were chosen for comparison. For cellular characterization, the following assays were conducted: proliferation assays, chemo – sensitivity assays for doxorubicin and paclitaxel, wound healing motility assays, matrix invasion assays, breast cancer cell growth to estradiol by chronic exposure to leptin, induction of endothelial permeability and tumorigenic potential in athymic mice with normo - versus hypercaloric diets with an evaluation of the epithelium – mesenchymal transformation proteins.ResultsTwo different cell lines, were established from patients with breast cancer: DSG-BC1, with a BMI of 21.9 kg/m2 and DSG-BC2, with a BMI of 31.5 kg/m2. In vitro, these two cell lines show differential growth rates, motility, chemosensitivity, vascular permeability, response to leptin with an activation of the JAK2/STAT3/AKT signaling pathway. In vivo, they displayed distinct tumorigenic potential. In particular, DSG-BC2, presented higher tumorigenicity when implanted in mice fed with a hypercaloric diet.DiscussionTo our knowledge, these primary cultures are the first in vitro representation of both breast cancer and obesity. DSG – BC2 presented a more aggressive in vivo and in vitro phenotype. These results support the hypothesis that breast cancer generated in an obese metabolic state may represent a contrasting variant within the same disease. This new model will allow both further comprehension, functional studies and the analysis of altered molecular mechanisms under the comorbidity of obesity and breast cancer

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

    Get PDF
    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
    corecore