64 research outputs found

    Dust emission from crusted surfaces: Insights from field measurements and modelling

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    Crusted surfaces can be major sources of mineral dust emission. Quantitative understanding of dust emission from crusted surfaces is limited, because (1) theories on dust emission are not well tested for such surfaces; and (2) modelling is hampered by a lack of input data sufficient to describe the surface conditions. Combining detailed field measurements with physics-based numerical modelling, we present new insights into dust emission from crusted surfaces. Our measurements confirm that crust erodibility and dust-emission intensity can increase or decrease after previous erosion events. To support interpretation of the measurements and to test the applicability of a state-of-the-art parameterisation to simulate dust emission from crusted surfaces, we apply the dust emission scheme of Shao (2004). Saltation flux, which is input to the scheme, is approximated using the parameterisation of Kawamura (1964) and a scaling factor obtained from observations. Limitations of this approach are discussed. Our results show that the dust emission scheme is suitable to estimate dust emission from crusted surfaces if accurate input data and parameters describing the soil-surface condition are provided. The parameters were optimized for each dust event to achieve a best estimate. The variation of the resulting parameter values confirms the observed variability of dust-emission efficiency between the events and provides further evidence that it was caused by variations in crust erodibility. Our study demonstrates that available physics-based dust-emission parameterisations are able to simulate dust emissions under complicated conditions, but also that refined information on the soil-surface conditions are needed as input to the schemes.This study was funded by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) grant KL 2932/1-1 awarded as a postdoctoral research fellowship to MK. TEG and RSVP acknowledge support from NASA grant NNX16AH13G. 15 NPW acknowledges support through funding from the Department of Interior, Bureau of Land Management. We thank Ralph Lorenz for providing pressure loggers and the Davis anemometer used on Site F. We also thank Sharalyn Peterson, Justin Van Zee, and Bradley Cooper for field and lab assistance. LPI point data were recorded using DIMA (https://jornada.nmsu.edu/monit-assess/dima). Any use of trade, product, or firm names is for descriptive purposes only and does not imply endorsement by the U.S. Government. The USDA is an equal opportunity provider and employer. We thank two anonymous reviewers for their positive and helpful comments.Peer ReviewedPostprint (author's final draft

    Enhancing wind erosion monitoring and assessment for U.S. rangelands

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    Wind erosion is a major resource concern for rangeland managers because it can impact soil health, ecosystem structure and function, hydrologic processes, agricultural production, and air quality. Despite its significance, little is known about which landscapes are eroding, by how much, and when. The National Wind Erosion Research Network was established in 2014 to develop tools for monitoring and assessing wind erosion and dust emissions across the United States. The Network, currently consisting of 13 sites, creates opportunities to enhance existing rangeland soil, vegetation, and air quality monitoring programs. Decision-support tools developed by the Network will improve the prediction and management of wind erosion across rangeland ecosystems. © 2017 The Author(s)The Rangelands archives are made available by the Society for Range Management and the University of Arizona Libraries. Contact [email protected] for further information

    Gravitational Lensing at Millimeter Wavelengths

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    With today's millimeter and submillimeter instruments observers use gravitational lensing mostly as a tool to boost the sensitivity when observing distant objects. This is evident through the dominance of gravitationally lensed objects among those detected in CO rotational lines at z>1. It is also evident in the use of lensing magnification by galaxy clusters in order to reach faint submm/mm continuum sources. There are, however, a few cases where millimeter lines have been directly involved in understanding lensing configurations. Future mm/submm instruments, such as the ALMA interferometer, will have both the sensitivity and the angular resolution to allow detailed observations of gravitational lenses. The almost constant sensitivity to dust emission over the redshift range z=1-10 means that the likelihood for strong lensing of dust continuum sources is much higher than for optically selected sources. A large number of new strong lenses are therefore likely to be discovered with ALMA, allowing a direct assessment of cosmological parameters through lens statistics. Combined with an angular resolution <0.1", ALMA will also be efficient for probing the gravitational potential of galaxy clusters, where we will be able to study both the sources and the lenses themselves, free of obscuration and extinction corrections, derive rotation curves for the lenses, their orientation and, thus, greatly constrain lens models.Comment: 69 pages, Review on quasar lensing. Part of a LNP Topical Volume on "Dark matter and gravitational lensing", eds. F. Courbin, D. Minniti. To be published by Springer-Verlag 2002. Paper with full resolution figures can be found at ftp://oden.oso.chalmers.se/pub/tommy/mmviews.ps.g

    New genetic loci link adipose and insulin biology to body fat distribution.

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    Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms

    AI is a viable alternative to high throughput screening: a 318-target study

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    : High throughput screening (HTS) is routinely used to identify bioactive small molecules. This requires physical compounds, which limits coverage of accessible chemical space. Computational approaches combined with vast on-demand chemical libraries can access far greater chemical space, provided that the predictive accuracy is sufficient to identify useful molecules. Through the largest and most diverse virtual HTS campaign reported to date, comprising 318 individual projects, we demonstrate that our AtomNet® convolutional neural network successfully finds novel hits across every major therapeutic area and protein class. We address historical limitations of computational screening by demonstrating success for target proteins without known binders, high-quality X-ray crystal structures, or manual cherry-picking of compounds. We show that the molecules selected by the AtomNet® model are novel drug-like scaffolds rather than minor modifications to known bioactive compounds. Our empirical results suggest that computational methods can substantially replace HTS as the first step of small-molecule drug discovery

    Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

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    Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

    Wind Erosion

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    Wind erosion refers to the detachment, transport, and deposition of sediment by wind. It is a dynamic, physical process where loose, dry, bare soils are transported by strong winds. Geomorphologists and other earth scientists usually consider wind erosion as a specific subdiscipline of a more broad study of aeolian (also spelled eolian) processes. The term aeolian is derived from the Greek god Aeolus, the keeper of the winds, so aeolian processes refer to effects produced by the force of the wind interacting with surface features. Although aeolian research spans a wide range of topics, which may even include research on other planets, in this chapter we will limit our focus to erosion of soils by the wind on the Earth’s surface, and more specifically on crop land and range land. The movement of sediment by wind has been occurring for many eons, as demonstrated by aeolian cross-bedding seen in wind-blown sands of ancient sandstone bedrock. Loess deposits are ubiquitous accumulations of aeolian sediments of silt, and smaller amounts of clay and sand, derived from wind-blown glacial outwash deposits or from deserts or playa lakes. Large dune fields and sand seas around the world provide further evidence of current and past aeolian environments (Fig. 14|1). Fixed or stable dunes are no longer active in the current climate but were active sand seas or dune fields in the past. Scientists have long been interested in the direct and indirect effects of wind erosion. The earliest publication relating to aeolian processes was written by a Flemish astronomer, Godefroy Wendelin, in 1646 (Stout et al., 2009). Wendelin’s paper (Wendelin, 1646) described the purple rain of Brussels that we now recognize as wet deposition of African windblown dust. Charles Darwin collected dust over the Atlantic Ocean that had fallen during his voyages on the HMS Beagle (Darwin, 1845). Recent analysis of this dust indicated it originated from the Western Sahara and molecular-microbiological methods demonstrated the presence of many viable microbes even today (Gorbushina et al., 2007)
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