164 research outputs found
The cold origin of the warm dust around epsilon Eridani
Context: The K2V star eps Eri hosts one known inner planet, an outer Kuiper
belt analog, and an inner disk of warm dust. Spitzer/IRS measurements indicate
that the warm dust is present at distances as close as a few AU from the star.
Its origin is puzzling, since an "asteroid belt" that could produce this dust
would be unstable because of the known inner planet. Aims: Here we test the
hypothesis that the observed warm dust is generated by collisions in the outer
belt and is transported inward by Poynting-Robertson (P-R) drag and strong
stellar winds. Methods: We simulated a steady-state distribution of dust
particles outside 10AU with a collisional code and in the inner region (r<10AU)
with single-particle numerical integrations. By assuming homogeneous spherical
dust grains composed of water ice and silicate, we calculated the thermal
emission of the dust and compared it with observations. We investigated two
different orbital configurations for the inner planet inferred from RV
measurements, one with a highly eccentric orbit of e=0.7 and another one with a
moderate one of e=0.25. We also produced a simulation without a planet.
Results: Our models can reproduce the shape and magnitude of the observed SED
from mid-IR to sub-mm wavelengths, as well as the Spitzer/MIPS radial
brightness profiles. The best-fit dust composition includes both ice and
silicates. The results are similar for the two possible planetary orbits and
without a planet. Conclusions: The observed warm dust in the system can indeed
stem from the outer belt and be transported inward by P-R and stellar wind
drag. The inner planet has little effect on the distribution of dust, so that
the planetary orbit could not be constrained. Reasonable agreement between the
model and observations can only be achieved by relaxing the assumption of
purely silicate dust and assuming a mixture of silicate and ice in comparable
amounts.Comment: 9 pages, 9 figures, abstract abridge
Entanglement entropy of the black hole horizon
We examine a possibility that, when a black hole is formed, the information
on the collapsed star is stored as the entanglement entropy between the outside
and the thin region (of the order of the Planck length) of the inside the
horizon. For this reason, we call this as the entanglement entropy of the black
hole ``horizon''. We construct two models, one is in the Minkowski spacetime
and the other is in the Rindler wedge. To calculate the entropy explicitly, we
assume that the thin regions of the order of the Planck length of the outside
and inside the horizon are completely entangled by quantum effects. We also use
a property of the entanglement entropy that it is symmetric under an
interchange of the observed and unobserved subsystems. Our setting and this
symmetric property substantially reduce the needed numerical calculation. As a
result of our analysis, we can explain the Bekenstein-Hawking entropy itself
(rather than its correction by matter fields) in the context of the
entanglement entropy.Comment: 28 pages, 5 figures, section 1 and the paragraph before subsection
3.1 are improved and enlarge
Debris Disks: Seeing Dust, Thinking of Planetesimals and Planets
Debris disks are optically thin, almost gas-free dusty disks observed around
a significant fraction of main-sequence stars older than about 10 Myr. Since
the circumstellar dust is short-lived, the very existence of these disks is
considered as evidence that dust-producing planetesimals are still present in
mature systems, in which planets have formed - or failed to form - a long time
ago. It is inferred that these planetesimals orbit their host stars at asteroid
to Kuiper-belt distances and continually supply fresh dust through mutual
collisions. This review outlines observational techniques and results on debris
disks, summarizes their essential physics and theoretical models, and then
places them into the general context of planetary systems, uncovering
interrelations between the disks, dust parent bodies, and planets. It is shown
that debris disks can serve as tracers of planetesimals and planets and shed
light on the planetesimal and planet formation processes that operated in these
systems in the past.Comment: Review paper, accepted for publication in "Research in Astronomy and
Astrophysics
Electronic Structure Calculation by First Principles for Strongly Correlated Electron Systems
Recent trends of ab initio studies and progress in methodologies for
electronic structure calculations of strongly correlated electron systems are
discussed. The interest for developing efficient methods is motivated by recent
discoveries and characterizations of strongly correlated electron materials and
by requirements for understanding mechanisms of intriguing phenomena beyond a
single-particle picture. A three-stage scheme is developed as renormalized
multi-scale solvers (RMS) utilizing the hierarchical electronic structure in
the energy space. It provides us with an ab initio downfolding of the global
band structure into low-energy effective models followed by low-energy solvers
for the models. The RMS method is illustrated with examples of several
materials. In particular, we overview cases such as dynamics of semiconductors,
transition metals and its compounds including iron-based superconductors and
perovskite oxides, as well as organic conductors of kappa-ET type.Comment: 44 pages including 38 figures, to appear in J. Phys. Soc. Jpn. as an
invited review pape
Early Gnathostome Phylogeny Revisited: Multiple Method Consensus
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.A series of recent studies recovered consistent phylogenetic scenarios of jawed vertebrates, such as the paraphyly of placoderms with respect to crown gnathostomes, and antiarchs as the sister group of all other jawed vertebrates. However, some of the hylogenetic relationships within the group have remained controversial, such as the positions of Entelognathus, ptyctodontids, and the Guiyu-lineage that comprises Guiyu, Psarolepis and Achoania. The revision of the dataset in a recent study reveals a modified phylogenetic hypothesis, which shows that some of these phylogenetic conflicts were sourced from a few inadvertent miscodings. The interrelationships of early gnathostomes are addressed based on a combined new dataset with 103 taxa and 335 characters, which is the most comprehensive morphological dataset constructed to date. This dataset is investigated in a phylogenetic context using maximum parsimony (MP), Bayesian inference (BI) and maximum likelihood (ML) approaches in an attempt to explore the consensus and incongruence between the hypotheses of early gnathostome interrelationships recovered from different methods. Our findings consistently corroborate the paraphyly of placoderms, all `acanthodians' as a paraphyletic stem group of chondrichthyans, Entelognathus as a stem gnathostome, and the Guiyu-lineage as stem sarcopterygians. The incongruence using different methods is less significant than the consensus, and mainly relates to the positions of the placoderm Wuttagoonaspis, the stem chondrichthyan Ramirosuarezia, and the stem osteichthyan LophosteusÐthe taxa that are either poorly known or highly specialized in character complement. Given that the different performances of each phylogenetic approach, our study provides an empirical case that the multiple phylogenetic analyses of
morphological data are mutually complementary rather than redundant
Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial
Background Non-alcoholic steatohepatitis (NASH) is a common type of chronic liver disease that can lead to cirrhosis. Obeticholic acid, a farnesoid X receptor agonist, has been shown to improve the histological features of NASH. Here we report results from a planned interim analysis of an ongoing, phase 3 study of obeticholic acid for NASH. Methods In this multicentre, randomised, double-blind, placebo-controlled study, adult patients with definite NASH,non-alcoholic fatty liver disease (NAFLD) activity score of at least 4, and fibrosis stages F2–F3, or F1 with at least oneaccompanying comorbidity, were randomly assigned using an interactive web response system in a 1:1:1 ratio to receive oral placebo, obeticholic acid 10 mg, or obeticholic acid 25 mg daily. Patients were excluded if cirrhosis, other chronic liver disease, elevated alcohol consumption, or confounding conditions were present. The primary endpointsfor the month-18 interim analysis were fibrosis improvement (≥1 stage) with no worsening of NASH, or NASH resolution with no worsening of fibrosis, with the study considered successful if either primary endpoint was met. Primary analyses were done by intention to treat, in patients with fibrosis stage F2–F3 who received at least one dose of treatment and reached, or would have reached, the month 18 visit by the prespecified interim analysis cutoff date. The study also evaluated other histological and biochemical markers of NASH and fibrosis, and safety. This study is ongoing, and registered with ClinicalTrials.gov, NCT02548351, and EudraCT, 20150-025601-6. Findings Between Dec 9, 2015, and Oct 26, 2018, 1968 patients with stage F1–F3 fibrosis were enrolled and received at least one dose of study treatment; 931 patients with stage F2–F3 fibrosis were included in the primary analysis (311 in the placebo group, 312 in the obeticholic acid 10 mg group, and 308 in the obeticholic acid 25 mg group). The fibrosis improvement endpoint was achieved by 37 (12%) patients in the placebo group, 55 (18%) in the obeticholic acid 10 mg group (p=0·045), and 71 (23%) in the obeticholic acid 25 mg group (p=0·0002). The NASH resolution endpoint was not met (25 [8%] patients in the placebo group, 35 [11%] in the obeticholic acid 10 mg group [p=0·18], and 36 [12%] in the obeticholic acid 25 mg group [p=0·13]). In the safety population (1968 patients with fibrosis stages F1–F3), the most common adverse event was pruritus (123 [19%] in the placebo group, 183 [28%] in the obeticholic acid 10 mg group, and 336 [51%] in the obeticholic acid 25 mg group); incidence was generally mild to moderate in severity. The overall safety profile was similar to that in previous studies, and incidence of serious adverse events was similar across treatment groups (75 [11%] patients in the placebo group, 72 [11%] in the obeticholic acid 10 mg group, and 93 [14%] in the obeticholic acid 25 mg group). Interpretation Obeticholic acid 25 mg significantly improved fibrosis and key components of NASH disease activity among patients with NASH. The results from this planned interim analysis show clinically significant histological improvement that is reasonably likely to predict clinical benefit. This study is ongoing to assess clinical outcomes
Charged-particle multiplicities in pp interactions at root s=900 GeV measured with the ATLAS detector at the LHC ATLAS Collaboration
The first measurements from proton–proton collisions recorded with the ATLAS detector at the LHC are presented. Data were collected in December 2009 using a minimum-bias trigger during collisions at a centre-of-mass energy of 900 GeV. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity, and the relationship between mean transverse momentum and charged-particle multiplicity are measured for events with at least one charged particle in the kinematic range |η|500 MeVpT>500 MeV. The measurements are compared to Monte Carlo models of proton–proton collisions and to results from other experiments at the same centre-of-mass energy. The charged-particle multiplicity per event and unit of pseudorapidity at η=0η=0 is measured to be 1.333±0.003(stat.)±0.040(syst.)1.333±0.003(stat.)±0.040(syst.), which is 5–15% higher than the Monte Carlo models predict
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