10 research outputs found
Serving Us Rights: Securing the Right to Food in Canada
- Publication venue
- Canadian Review of Social Policy / Revue canadienne de politique sociale
- Publication date
- 14/12/2021
- Field of study
In recent decades, Canada has consistently failed to uphold basic human rights, including the right to food. This has caused widespread and persistent household food insecurity (HFI) which has become a serious, albeit overlooked, public health concern. Working from a political economic perspective, this article situates HFI within the context of the poverty resulting from neoliberal “rollbacks” to the welfare state. The majority of community and policy responses to HFI focus on the production or redistribution of food, which misses the underlying issue of inadequate income. These responses may even perpetuate food insecurity by offloading safety net functions onto corporations and communities that cannot compensate for welfare programs. In order to strengthen income-based responses to food insecurity, we recommend policy interventions under the “right to food” framework, which places primary responsibility on the state. But unlike traditionally legal conceptions of the right to food, we emphasize its utility as a tool for mobilizing civil society, which is a powerful yet underutilized source of accountability to state obligations. This approach therefore combines political action with policymaking, and civil society with senior governments, in the collective realization of the right to food
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers
- Author
- Aalfs Cora M.
- Aaltonen Kirsimari
- Adenis Claude
- Adlard Julian
- Agnarsson Bjarni A.
- Aittomäki Kristiina
- Alonso Rosario
- Amadori Alberto
- Andrulis Irene L.
- Angelakos Maggie
- Antoniou Antonis C.
- Ardern Jones Audrey
- Ardnor Christina Edwinsdotter
- Arnold Norbert
- Arun Banu K.
- Arver Brita
- Attard Virginia
- Ausems M. G. E. M.
- Balmaña J.
- Balogh Maria
- Bancroft Elizabeth
- Bardel Claire
- Bardsley Cathryn
- Barile Monica
- Barjhoux Laure
- Barouk Simonet Emmanuelle
- Barroso Alicia
- Barrowdale Daniel
- Barton David
- Barwell Julian
- Belotti Muriel
- Benitez Javier
- Berger Andreas
- Berlin Cheryl
- Berthet Pascaline
- Bignon Yves Jean
- Blanco Amie
- Blanco Ignacio
- Blein Sophie
- Blok M. J.
- Blomqvist Drs Carl
- Bonadona Valérie
- Bonanni Bernardo
- Bonnet Françoise
- Borg Ake
- Bourdon Violaine
- Bove Betsy
- Bozsik Aniko
- Bradshaw Nicola
- Brady Angela
- Breast Cancer Family Registry Null
- Bressac de Paillerets Brigitte
- Brewer Carole
- Brice Glen
- Bronner Myriam
- Bubien Virginie
- Buecher Bruno
- Bustinza Gisela Barbany
- Buys Saundra S.
- Caldes Trinidad
- Calender Alain
- Caligo Maria A.
- Capella Gabriel
- Capone Gabriele L.
- Caron Olivier
- Carter Jonathan
- Castro Elena
- Chan Salina
- Chenevix Trench Georgia
- Chung Wendy K.
- Claber Oonagh
- Claes Kathleen
- Colas Chrystelle
- Cole Trevor
- Collier Rebecca
- Collonge Rame Marie Agnès
- Collée J. M.
- Conejero Raquel Andrés
- Conrad Peggy
- Cook Jackie
- Corines Marina
- Coron Fanny
- Couch Fergus J.
- Coulet Florence
- Coupier Isabelle
- Cox David G.
- Craven Caroline
- Crawford Beth
- Crawford Gillian
- Damette Alexandre
- Damiola Francesca
- Danjean Vincent
- Davidson Rosemarie
- de Bock G. H.
- de la Hoya Miguel
- de Lange J. L.
- De Leeneer Kim
- de Pauw Antoine
- Del Valle Jesús
- Delatycki Martin
- della Puppa Lara
- Delnatte Capucine
- Demange Liliane
- Dennis Joe
- Devilee Peter
- Diez Orland
- Ding Chun
- Ding Yuan Chun
- Dishon Sara
- Disilvestro Paul A.
- Dite Gillian
- Ditsch Nina
- Dolcetti Riccardo
- Domchek Susan M.
- Domokos Gabriella
- Donaldson Alan
- Dorfling Cecilia M.
- Dorkins Huw
- Douglas Fiona
- Dreyfus Hélène
- Driessen Rebecca
- Drummond Sarah
- Dumont Martine
- Duncan Alexis
- Durda Katarzyna
- Durell Sarah
- Eason Jacqueline
- Easton Douglas F.
- Eccles Diana
- Eddy Charlotte
- Eeles Ros
- Eglitis Drs Janis
- Ehrencrona Hans
- Einbeigi Zakaria
- Eisinger François
- Ejlertsen Bent
- Ellis Ian
- Ellis Steve
- Emanuelsson Monica
- Embrace Null
- Engel Christoph
- Erkkilä Irja
- Evans D. Gareth
- Faivre Laurence
- Feillel Viviane
- Ferenczi Judit
- Ferrer Sandra Fert
- Fineberg Elena
- Fink Retter Anneliese
- Foo Claire
- Foretova Lenka
- Foulkes William
- Fournier Joëlle
- Franko Judit
- Fricker Jean Pierre
- Friedman Eitan
- Frost Debra
- Frénay Marc
- Garber Judy
- Gauthier Villars Marion
- Gayther Simon
- Gehrig Andrea
- Gerdes Anne Marie
- Gibson Sarah
- Gille J. J. P.
- Giraud Sophie
- Gladieff Laurence
- Glendon Gord
- Godwin Andrew K.
- Goff Sheila
- Goldgar David E.
- Golmard Lisa
- Goodman Selina
- Greene Mark H.
- Gregory Helen
- Griškevicius Laimonas
- Gronwald Jacek
- Guimbaud Rosine
- Gómez Garcia E. B.
- Halliday Dorothy
- Hamann Ute
- Handallou Sandrine
- Hansen Thomas V. O.
- Haque Eshika
- Harbst Katja
- Hardouin Agnès
- Harrington Patricia
- Harris Marion
- Healey Sue
- Henriksson Karin
- Hill Kathryn
- Hodgson Shirley
- Hoffman Jonathan
- Hogervorst Frans B. L.
- Hooning M. J.
- Houdayer Claude
- Houghton Catherine
- Houlston Richard
- Imyanitov Evgeny N.
- Isaacs Claudine
- Izatt Louise
- Jacobs Chris
- Jacobs Lauren
- Jager Agnes
- Jakubowska Anna
- James Margaret
- Janavicius Ramunas
- Jaworska Bieniek Katarzyna
- Jeffers Lisa
- Jensen Uffe Birk
- Jernström Helena
- Jobson Irene
- Karlan Beth Y.
- Karlsson Per
- Kast Karin
- Kaulich Daphne Geschwantler
- Kennedy M. John
- Kets Carolien M.
- Kientz Caroline
- Killick Emma
- Kivuva Emma
- Kleibl Zdenek
- Kohut Kelly
- Konstantopoulou Irene
- Krilova Anna
- Kristoffersson Ulf
- Kruse Torben A.
- Kuchenbaecker Karoline B.
- Kulkarni Anjana
- Kwan Lorna
- Laitman Yael
- Lalloo Fiona
- Lambo Rossana
- Langman Caroline
- Lasset Christine
- Lazaro Conxi
- Lebrun Marine
- Lee Andrew
- Lee Robin
- Lefol Cédrick
- Lehmann Anna
- Lejbkowicz Flavio
- Leroux Dominique
- Lester Jenny
- Lidereau Rosette
- Liedgren Sigrun
- Liljegren Annelie
- Lincoln Anne
- Lindblom Annika
- Lindeman Geoffrey
- Lindor Noralane M.
- Loman Niklas
- Longmuir Mark
- Longy Michel
- Loranger Kate
- Lubinski Jan
- Lucassen Anneke
- Lynch Henry T.
- Léone Mélanie
- Machackova Eva
- Mai Phuong L.
- Mak Julie
- Male Alison
- Manoukian Siranoush
- Markov Nadja Bogdanova
- Martayan Aline
- Martin Sue
- Maskiell Judi
- Maugard Christine
- Mazoyer Sylvie
- Mcbride Donna
- Mccann Emma
- Mcguffog Lesley
- Mcleod Diane
- Meijers Heijboer Hanne E. J.
- Meindl Alfons
- Melin Beatrice
- Mensenkamp A. R.
- Miedzybrodzka Zosia
- Mitchell Gillian
- Moncoutier Virginie
- Montagna Marco
- Morrison Patrick J.
- Mortemousque Isabelle
- Mourits M. J.
- Muller Danièle
- Mulligan Anna Marie
- Muranen Taru A.
- Murday Victoria
- Murray Alexandra
- Nathanson Katherine L.
- Neuhausen Susan L.
- Nevanlinna Heli
- Niederacher Dieter
- Niedermayr Eveline
- Nielsen Finn C.
- Niu Qun
- Noguchi Tetsuro
- Nogues Catherine
- Nordling Margareta
- Nussbaum Robert L.
- O'Conor Michelle
- Obdeijn I. M.
- Offit Kenneth
- Olah Edith
- Olopade Olufunmilayo I.
- Olsson Håkan
- Olswold Curtis
- Ong Kai Ren
- Oosterwijk Jan C.
- Orsulic Sandra
- Osorio Ana
- OTTINI LAURA
- Overbeek L. I. H.
- Page Elizabeth
- Palola Virpi
- Pankratz Vernon S.
- Papi Laura
- Papp Janos
- Paterson Joan
- Pedersen Inge Sokilde
- Peissel Bernard
- Peixoto Ana
- Pensotti Valeria
- Peterlongo Paolo
- Peyrat Jean Philippe
- Peysselon Magalie
- Pfeiler Georg
- Pharoah Paul D. P.
- Phelan Catherine M.
- Piedmonte Marion
- Pigg Maritta Hellström
- Pilato Brunella
- Pinchev Mila
- Pinto Pedro
- Pita Guillermo
- Platte Radka
- Plendl Hansjoerg
- Pocza Timea
- Pohlreich Petr
- Porteous Mary E.
- Preisler Adams Sabine
- Prieur Fabienne
- Pujol Pascal
- Pye Carole
- Quarrell Oliver
- Radice Paolo
- Rahman Nazneen
- Ramus Susan J.
- Rantala Johanna
- Rappaport Christine
- Rea Gillian
- Rebbeck Timothy R.
- Rebischung Christine
- Remenieras Audrey
- Rennert Gad
- Rhiem Kerstin
- Robson Mark
- Rocha Patrícia
- Rogers Mark T.
- Rookus Matti A.
- Rosenquist Richard
- Rouleau Etienne
- Rudaitis Vilius
- Révillion Françoise
- Santos Catarina
- Sawyer Sarah
- Schmidt M. K.
- Schmutzler Rita K.
- Scuvera Giulietta
- Searle Anne
- Segota Ena
- Seldon Joyce
- Senter Leigha
- Serra Feliu Gemma
- Sevenet Nicolas
- Seynaeve C.
- Shanley Susan
- Side Lucy E.
- Siesling S.
- Simard Jacques
- Singer Christian F.
- Sinilnikova Olga M.
- Smalley Sarah
- Snadden Lesley
- Snyder Carrie L.
- Sobol Hagay
- Sokolowska Johanna
- Soller Maria
- Sornin Valérie
- Soubrier Florent
- Soucy Penny
- Spurdle Amanda B.
- Stayner Barbara
- Steele Linda
- Steinemann Doris
- Stengrevics Aivars
- Stenmark Askmalm Marie
- Stewart Nicola
- Stoppa Lyonnet Dominique
- Sukiennicki Grzegorz
- Sutter Christian
- Sweet Kevin
- Szabo Csilla I.
- Taylor Amy
- Taylor Jane
- Tchatchou Sandrine
- Tea Muy Kheng
- Teixeira Manuel R.
- Terry Mary Beth
- Teulé Alex
- Thelander Margo
- Thomas Gilles
- Thomassen Mads
- Thompson Ella
- Thorne Heather
- Tibiletti Maria Grazia
- Tihomirova Laima
- Tirapo Carole
- Tischkowitz Marc
- Tobias Ed
- Toland Amanda Ewart
- Tollenaar R. A. E. M.
- Tommasi Stefania
- Toulas Christine
- Tranchant Martine
- Tripathi Vishakha
- Tsimiklis Helen
- Tung Nadine
- Uhrhammer Nancy
- van Asperen C. J.
- van Cronenburg T. C. T. E. F.
- van den Ouweland Ans M. W.
- van der Hout A. H.
- van der Luijt Rob B.
- van Deurzen C. H. M.
- Van Le Linda
- van Leeuwen Flora E.
- van Os T. A. M.
- van Rensburg Elizabeth J.
- van Roozendaal Kees E. P.
- Varesco Liliana
- Varon Mateeva Raymonda
- Vasen H. F.
- Vaszko Tibor
- Vennin Philippe
- Verhoef S.
- Verny Pierre Carole
- Viel Alessandra
- Vijai Joseph
- von Wachenfeldt Anna
- Vénat Bouvet Laurence
- Waisfisz Q.
- Walker Lisa
- Wang Gohrke Shan
- Wappenschmidt Barbara
- Watt Catherine
- Weaver Jo Ellen
- Weitzel Jeffrey N.
- Wiggins Jennifer
- Wijnands R.
- Wijnen J. T.
- Winchester Lizzie
- Wozniak Eva
- Yannoukakos Drakoulis
- Zaffaroni Daniela
- Zidan Jamal
- Zikan Michal
- Zvocec Cecilia
- Öfverholm Anna
- Publication venue
- Publication date
- 01/01/2015
- Field of study
Introduction: Individuals carrying pathogenic mutations in the BRCA1 and BRCA2 genes have a high lifetime risk of breast cancer. BRCA1 and BRCA2 are involved in DNA double-strand break repair, DNA alterations that can be caused by exposure to reactive oxygen species, a main source of which are mitochondria. Mitochondrial genome variations affect electron transport chain efficiency and reactive oxygen species production. Individuals with different mitochondrial haplogroups differ in their metabolism and sensitivity to oxidative stress. Variability in mitochondrial genetic background can alter reactive oxygen species production, leading to cancer risk. In the present study, we tested the hypothesis that mitochondrial haplogroups modify breast cancer risk in BRCA1/2 mutation carriers. Methods: We genotyped 22,214 (11,421 affected, 10,793 unaffected) mutation carriers belonging to the Consortium of Investigators of Modifiers of BRCA1/2 for 129 mitochondrial polymorphisms using the iCOGS array. Haplogroup inference and association detection were performed using a phylogenetic approach. ALTree was applied to explore the reference mitochondrial evolutionary tree and detect subclades enriched in affected or unaffected individuals. Results: We discovered that subclade T1a1 was depleted in affected BRCA2 mutation carriers compared with the rest of clade T (hazard ratio (HR) = 0.55; 95% confidence interval (CI), 0.34 to 0.88; P = 0.01). Compared with the most frequent haplogroup in the general population (that is, H and T clades), the T1a1 haplogroup has a HR of 0.62 (95% CI, 0.40 to 0.95; P = 0.03). We also identified three potential susceptibility loci, including G13708A/rs28359178, which has demonstrated an inverse association with familial breast cancer risk. Conclusions: This study illustrates how original approaches such as the phylogeny-based method we used can empower classical molecular epidemiological studies aimed at identifying association or risk modification effects.Peer reviewe
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
- Author
- Aalfs C.M. (Cora)
- Adenis C. (Claude)
- Adlard J.W. (Julian)
- Agata S. (Simona)
- Agnarsson B.A. (Bjarni)
- Aittomäki K. (Kristiina)
- Andersen M.K. (Mette)
- Andrulis I.L. (Irene)
- Angelakos M. (Maggie)
- Antoniou A.C. (Antonis)
- Ardern-Jones A. (Audrey)
- Ardnor C.E. (Christina Edwinsdotter)
- Arnold N. (Norbert)
- Arun B.K. (Banu)
- Arver B. (Brita Wasteson)
- Asperen C.J. (Christi) van
- Attard V. (Virginia)
- Ausems M.G.E.M. (Margreet)
- Bacot F. (Francois)
- Bae-Jump V.L. (Victoria L.)
- Balmana J. (Judith)
- Bancroft E.K. (Elizabeth)
- Bardsley C. (Cathryn)
- Barjhoux L. (Laure)
- Barkardottir R.B. (Rosa)
- Barouk-Simonet E. (Emmanuelle)
- Barrowdale D. (Daniel)
- Barton D.E. (David)
- Barwell J. (Julian)
- Beattie M.S. (Mary)
- Belotti M. (Muriel)
- Benítez J. (Javier)
- Berlin C. (Cheryl)
- Berthet P. (Pascaline)
- Bignon Y.-J. (Yves-Jean)
- Bignon Y.-J. (Yves-Jean)
- Blanco I. (Ignacio)
- Blank S.V. (Stephanie)
- Blok M.J. (Marinus)
- Bock G.H. (Geertruida) de
- Bonadona V. (Valérie)
- Bonnani B. (Bernardo)
- Bonnet F. (Françoise)
- Borg Å. (Åke)
- Bourdon V. (Violaine)
- Bradshaw N. (Nicola)
- Brady A.F. (Angela)
- Bressac-de Paillerets B. (Brigitte)
- Brewer C. (C.)
- Brewer C. (Carole)
- Brice G. (Glen)
- Bronner M. (Myriam)
- Brunet J. (Joan)
- Bubien V. (Virginie)
- Buecher B. (Bruno)
- Bustinza G.B.
- Buys S.S. (Saundra)
- Caldes T. (Trinidad)
- Calender A. (Alain)
- Caligo M.A. (Maria)
- Campbell I. (Ian)
- Caron O. (Olivier)
- Castera L. (Laurent)
- Castro E. (Elena)
- Chan S. (Salina)
- Chenevix-Trench G. (Georgia)
- Chiquette J. (Jocelyne)
- Chung W.K. (Wendy)
- Claber O. (Oonagh)
- Claes K. (Kathleen)
- Cohn D.E. (David)
- Colas C. (Chrystelle)
- Cole T.J. (Trevor)
- Collier R. (Rebecca)
- Collée J.M. (Margriet)
- Cook J. (Jackie)
- Coron F. (Fanny)
- Couch F.J. (Fergus)
- Coulet F. (Florence)
- Coupier I. (Isabelle)
- Crawford G. (Gabe)
- Cronenburg T.C.T.E.F. van
- Cunningham J. (Jane)
- Daly M.B. (Mary)
- Damiola F. (Francesca)
- Damiola F. (Francesca)
- Davidson R. (Rosemarie)
- Deissler H. (Helmut)
- Delnatte C.D. (Capucine)
- Demange L. (Liliane)
- Dennis J. (Joe)
- Deurzen C.H.M. (Carolien) van
- Devilee P. (Peter)
- Devilee P. (Peter)
- Dicks E. (Ed)
- Diez O. (Orland)
- Ding Y.C. (Yuan)
- Dite G.S. (Gillian)
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- Domchek S.M. (Susan)
- Donaldson A. (Alan)
- Dorfling C.M. (Cecelia)
- Dorkins H. (Huw)
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- Douglas F. (Fiona)
- Dreyfus H. (Hélène)
- Drummond S. (Sarah)
- Duncan A. (Alexis)
- Dunning A.M. (Alison)
- Durda K. (Katarzyna)
- Durell S. (Sarah)
- Durán M. (Mercedes)
- Eason J. (Jacqueline)
- Easton D.F. (Douglas)
- Eccles D. (Diana)
- Eddy C. (Charlotte)
- Eeles R. (Rosalind)
- Ehrencrona H. (Hans)
- Einbeigi Z. (Zakaria)
- Eisinger F. (François)
- Ejlertsen B. (Bent)
- Ellis I.O. (Ian)
- Ellis S. (Steve)
- Ellis S.D. (Steve)
- Emanuelsson M. (Monica)
- Engel C. (Christoph)
- Engert S. (Stefanie)
- Evans D.G. (Gareth)
- Ewart-Toland A. (Amanda)
- Faivre L. (Laurence)
- Feillel V. (Viviane)
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- Fineberg E. (Elena)
- Fineberg E. (Elena)
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- Fredericksen Z. (Zachary)
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- Friedman E. (Eitan)
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- Gadzicki D. (Dorothea)
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- Garber J.
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- Gauthier-Villars M. (Marion)
- Gehrig P.A. (Paola A.)
- Gerdes A-M. (Anne-Marie)
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- Giraud S. (Sophie)
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- Goldgar D. (David)
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- Gregory H. (Helen)
- Gronwald J. (Jacek)
- Gschwantler-Kaulich D. (Daphne)
- Guimbaud R. (Rosine)
- Gómez García E.B. (Encarna)
- Hall A.S. (Alistair)
- Halliday D. (Dorothy)
- Hamann U. (Ute)
- Handallou S. (Sandrine)
- Hansen T.V.O. (Thomas)
- Haque E. (Eshika)
- Harbst K. (Katja)
- Hardouin A. (Agnès)
- hardouin A. (Agnès)
- Hart S. (Stewart)
- Healey S. (Sue)
- Henriksson K. (Karin)
- Herzog J. (Josef)
- Hodgson S.V. (Shirley)
- Hoffman J. (Jonathan)
- Hogervorst F.B.L. (Frans)
- Hooning M.J. (Maartje)
- Houdayer C. (Claude)
- Houghton C. (Catherine)
- Houlston R. (Richard)
- Hout A.H. (Annemarie) van der
- Hoya M. (Miguel) de La
- Huo D. (Dezheng)
- Huzarski T. (Tomasz)
- Imyanitov E.N. (Evgeny)
- Izatt L. (Louise)
- Izatt L. (Louise)
- Jacobs C. (Chris)
- Jakubowska A. (Anna)
- James M. (Margaret)
- James P.A. (Paul )
- Janavicius R. (Ramunas)
- Jaworska K. (Katarzyna)
- Jeffers L. (Lisa)
- Jensen U.B.
- Jernström H. (H.)
- Jobson I. (Irene)
- John E.M. (Esther)
- Jønson L. (Lars)
- Karlan B.Y. (Beth)
- Karlsson P. (Per)
- Kast K. (Karin)
- Kauff N. (Noah)
- Kaufman B. (Bella)
- Kennedy M.J. (John)
- Kets C.M. (Marleen)
- Kientz C. (Caroline)
- Killick S.R.
- Kivuva E. (Emma)
- Kohut K. (Kelly)
- Kosel M. (Matthew)
- Kristoffersson U. (Ulf)
- Kruse T.A. (Torben)
- Kuchenbaecker K.B. (Karoline)
- Kulkarni A. (Anjana)
- Kwong A. (Ava)
- Laitman Y. (Yael)
- Lalloo F. (Fiona)
- Lange J.L. (J.) de
- Langman C. (Caroline)
- Lasa A. (Adriana)
- Lasset C. (Christine)
- Lebrun M. (Marine)
- Lee A. (Andrew)
- Leeuwen F.E. (Flora) van
- Leeuwen F.E. (Flora) van
- Lehmann A. (Anna)
- Lejbkowicz F. (Flavio)
- Leroux D. (Dominique)
- Lester K.J. (Kathryn)
- Lidereau R. (Rosette)
- Liedgren S. (Sigrun)
- Ligtenberg M.J. (Marjolijn)
- Liljegren A. (Annelie)
- Lindblom A. (Annika)
- Lindor N.M. (Noralane)
- Loman N. (Niklas)
- Longmuir M. (Mark)
- Longy M. (Michel)
- Loud J.T. (Jennifer)
- Lu K.H. (Karen)
- Lubinski J. (Jan)
- Lucassen A. (Anneke)
- Luijt R.B. (Rob) van der
- Lynch H. (Henry)
- Lázaro C. (Conxi)
- Léone M. (Mélanie)
- Mai P.L. (Phuong)
- Male A. (Alison)
- Manoukian S. (Siranoush)
- Martin S. (Sue)
- Maskiell J. (Judi)
- Mazoyer S. (Sylvie)
- Mazoyer S. (Sylvie)
- McBride D. (Donna)
- McCann E. (Emma)
- McGuffog L. (Lesley)
- McLeod D. (Diane)
- Meijers-Heijboer E.J. (Hanne)
- Meijers-Heijboer H. (Hanne)
- Meindl A. (Alfons)
- Melin B. (Beatrice)
- Melloni G. (Giulia)
- Melville S.A. (Scott)
- Mensenkamp A.R. (Arjen)
- Miedzybrodzka Z. (Zosia)
- Miron A. (Alexander)
- Moeller S.T. (Sanne Traasdahl)
- Moncoutier V. (Virginie)
- Montagna M. (Marco)
- Morrison P.J. (Patrick)
- Mortemousque I. (Isabelle)
- Mourits M.J. (Marjan)
- Muller D.W. (Danièle)
- Mulligan A.M. (Anna Marie)
- Muranen T.A. (Taru)
- Murday V. (Victoria)
- Murray A. (Alexandra)
- Murray A. (Anna)
- Narod S. (Steven)
- Nathanson K.L. (Katherine)
- Neuhausen S.L. (Susan)
- Nevanlinna H. (Heli)
- Niederacher D. (Dieter)
- Niedermayr E. (Eveline)
- Nielsen F.C. (Finn)
- Noguchi T. (Tetsuro)
- Nogues C. (Catherine)
- Nordling M. (Margareta)
- Offit K. (Kenneth)
- Olah E.
- Olopade O.I. (Olofunmilayo)
- Olsson H.
- Olswold C. (Curtis)
- Ong K.-R. (Kai-Ren)
- Oosterwijk J.C. (Jan)
- Orsulic S. (Sandra)
- Os T.A.M. (Theo) van
- Os T.A.M. (Theo) van
- Osorio A. (Ana)
- Ottini L. (Laura)
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- Ozcelik H. (Hilmi)
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- Pedersen I.S. (Inge Sokilde)
- Peissel B. (Bernard)
- Pensotti V. (Valeria)
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- Tibiletti M.G. (Maria Grazia)
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- Tischkowitz M. (Marc)
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- Tollenaar R.A.E.M. (Rob)
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- Tripathi V. (Vishakha)
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- Varesco L. (Liliana)
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- Verhoef S.
- Verhoef S. (S.)
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- Viel A. (Alessandra)
- Vijai J. (Joseph)
- Vincent D. (Daniel)
- Volorio S. (Sara)
- Vénat-Bouvet L. (Laurence)
- Wachenfeldt A. (Anna) von
- Waisfisz Q. (Quinten)
- Walker L.J. (Lisa)
- Walsh C.S. (Christine)
- Wang C. (Chen)
- Wang X. (Xianshu)
- Wapenschmidt B. (Barbara)
- Watt C. (Catherine)
- Weaver J. (JoEllen)
- Weber B.H.F. (Bernhard)
- Weitzel J.N. (Jeffrey)
- Wiggins J. (Jennifer)
- Wijnen J.T. (Juul)
- Wijnen J.T. (Juul)
- Winchester L. (Lizzie)
- Yannoukakos D. (Drakoulis)
- Złowocka-Perłowska E. (Elzbieta)
- Öfverholm A. (Anna)
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 15/04/2013
- Field of study
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7×10-8, HR = 1.14, 95% CI: 1.09-1.20). In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4×10-8, HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4×10-8, HR = 1.20, 95% CI: 1.17-1.38). The 4q32.3 locus was not associated with ovarian cancer risk in the general population or BRCA2 carriers, suggesting a BRCA1-specific associat
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19
- Author
- ?ivko Iris
- Abbass Hakam
- Abdeladim Lilia
- Abdelhady Hesham
- Abdelkharim Hussam
- Abdelrazik Marwa
- Abdi Zakee
- Abdukahil Sheryl Ann
- Abel Lynn
- Abraham Jacinta
- Abrahamson Gail
- Abusamra Yousuf
- Aceto Romina
- Adams Nick
- Adams Peter
- Adebambo Olumide
- Adhikari Neill
- Adhikari Sheetal
- Affleck Julia
- Agha Gloria
- Aghemo Alessio
- Agno Ronan
- Ahmad Norfaizan
- Ain Quratul
- Ainscough Kate
- Ainsworth James
- Aitken Lindianne
- Akamp Ceren
- Al Enezi Farhan
- Al-Bassam Wisam
- Al-Beidh Farah
- Albert Martin
- Albrett Jonathan
- Alderman Meera
- Aldo Bonizzoni Matteo
- Alegria Ana
- Alessandro Carà Gianmarco
- Alexander Brian
- Alexander Peter
- Alfonso Jordan
- Ali Maryam
- Ali Murtaza
- Allam Hayat
- Allen Barbara
- Allen Louise
- Allibone Suzanne
- Almeshhedani Hasham
- AlQahtani Samah
- Alswaidan Lolowa
- Altomy Mohammed
- Al Amri Ali
- Al Qasim Eman
- Amatya Sameena
- Ambrosino Richard
- Anderson Thomas
- Andreae Mark
- Aneman Anders
- Angus Derek C.
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Anne-Laure Fedou
- Anstey Matthew
- Antcliffe David
- Anthony Alpha
- Antoine Marchalot
- Antoine Pierre
- Antoine Studer
- Anumakonda Vikram
- Aparicio Christelle
- Aquino Maia
- Arabi Yaseen M.
- Arachchige Malka
- Aravindan Latha
- Arbane Gill
- Archambault Patrick
- Archer Simon
- Aref Noah
- Arias Ana-Marie
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- McArthur Colin J.
- McAuley Daniel F.
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- McCallion Edmund
- McCarthy Aine
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- McGuinness Shay P.
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- Oza Deepali
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- Paramasivam Elankumaran
- Parekh Dhruv
- Parikh Harshel G.
- Parke Rachael L.
- Parker Jane C.
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- Ralston Maximillian
- Ramakrishnan N
- Ramali Mohamed
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- Trimmer Ken
- Triulzi Darrell
- Troeman Darren
- Trues Estefania
- Truman Nicholas
- Tsakiridou Kyriaki
- Tsang Jennifer
- Tsinaslanidis Georgios
- Tuckwell Caroline
- Tully Redmond
- Tully Riona
- Tung Raymond
- Tupper-Carey Daryl
- Turgeon Alexis F.
- Turki Salah
- Turner Anne M.
- Turner Elizabeth
- Turner Keri
- Turner-Bone Ian
- Turns Margaret
- TV Bharath
- Udayanga Ishara
- Uddin Ruzena
- Udy Andrew
- Ullmann Hannah
- Umrani Zulfiqar
- Unsworth Adam
- Uriel Alison
- Ustianowski Andrew
- Uyeki Tim
- Vaara Suvi
- Vaduganathan Muthiah
- Vahtera Annukka
- Vale Cassandra
- Valentine Eliza
- Vamplew Luke
- van Amerongen Roosmarijn
- van Bentum-Puijk Wilma
- van Bree Sjoerd
- van de Veerdonk Frank L.
- van den Berg Lettie
- van den Oever Huub
- van der Eng Hetty
- Van Der Heyden Kymbalee
- van der Kraan-Donker Annemarie
- van Gulik Laura
- van Haren Frank
- Van Hecke Jolien
- van Kimmenade Roland
- van Nieuwkoop Kees
- van Zanten Arthur
- van Zuylen Tamara
- Van?t Hoff William
- Vandewoestyne Sophie
- Vanjak Christian
- Vanmali Piyush
- van Opdorp Marjolein
- van Vonderen Marit
- Vargas Jr. Jesus
- Varghese Siby
- Vautier Sarah
- Vazquez-Grande Gloria
- Veenith Tonny
- Veillard Marion
- Venkatesh Bala
- Verlander Mark
- Vermassen Joris
- Vermeiren Daisy
- Vermont - van der Staaij Janine
- Verrier Nathalie
- Vertue Mark
- Verula Jerik
- Victor Saji
- Viehman Alex
- Vieillard-Baron Antoine
- Vignesh C
- Villot Solenne
- Vilá Clara
- Vincent Rachel
- Virdee Satwinder
- Visentin Elisa
- Visser Yorik
- Vita Tina
- Vivier Dominique
- Vodovar Dominique
- Voicu Sebastian
- Voigt Ingo
- Voiriot Guillaume
- Volkov Lev
- Voza Gennaro
- Vuylsteke Alain
- Wada Asako
- Waddington Natalia
- Wahl Nadine
- Waite Alicia
- Walden Andrew
- Walker Gena
- Walker Rachel
- Walker Susan
- Walsh Joanne
- Walsh Tim
- Walsham James
- Walton Catherine
- Wang Shu
- Ward Geraldine
- Ward Kathryn
- Ward Luke
- Warnapura Loku
- Warnock Majella
- Watchorn Olivia
- Waters Abby
- Waterson Sharon
- Watkins Claire
- Watpool Irene
- Watters Malcolm
- Watts Angela
- Waugh Victoria
- Webb Steve A.
- Weber Lisa
- Webster Denise
- Weerasinghe Thanuja
- Weismann Dirk
- Weiss Daniel
- Weissman Alexandra
- Wells Alan
- Wells Colin
- Wells Karen
- Welters Ingeborg
- West Lauren
- Westlake Samantha
- Wetherill Bill
- Wetzold Richard
- Whileman Amanda
- Whitbread Jennifer
- White Alison
- White Hayden
- White Ian
- White Katie
- Whitehead Christina
- Whitehouse Tony
- Wibrow Bradley
- Wigbers Jeanette
- Wijewardena Gayathri
- Wilby Elizabeth
- Wilcox Elizabeth
- Wilcox Louise
- Wild Helen
- Wild Laura
- Wilding Laura
- Wiles Matt
- Wiley Daisy
- Wilhelmsen Elva
- Wilkinson Dean
- Willams Felicity
- Williams Alexandra
- Williams Angharad
- Williams Anna
- Williams Erin
- Williams Gemma
- Williams Hannah
- Williams Karen
- Williams Marie
- Williams Patricia
- Williams Penny
- Williams Tony
- Williams Virginie
- Williamson Dawn
- Williamson James D
- Willis Joanna
- Willson Jayne
- Wilson Anna
- Wilson Craig
- Wilson Jean
- Wilson Maggie
- Winters James
- Winters Lauren
- Wise Matt
- Wisniewski Mary
- Wittekamp Bastiaan
- Wittenberg Wendy
- Wnuk Chris
- Woelke Amy
- Wong Jenny
- Wong Onyee
- Wood Erica
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Woodward Robert
- Woolett Melissa
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wrey Brown Caroline
- Wright Chris
- Wright Kim
- Wunderley Renee
- Wyatt Rachel
- Wylie Katharine
- Xavier Kugan
- Yamagishi Yoshiaki
- Yamashita Chizuru
- Yang Yang
- Yarad Elizabeth
- Yates Bryan
- Yates David
- Yealy Donald
- Young Ian
- Young Meredith
- Young Paul
- Youngstein Taryn
- Yu Haili
- Yusuff Hakeem
- Zaharia Mihaela
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zarychanski Ryan
- Zdanavidiene Ausra
- Zhao Xiao
- Zinzoni Vanessa
- Zitter Letizia
- Zouita Louisa
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 11/04/2023
- Field of study
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19.
DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022).
INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days.
MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes.
RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively).
CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes.
TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570
Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer
- Author
- Abdi Ehtesham
- Abraham Jean
- Abreu Miguel
- Adams Sylvia
- Aktan G.
- Al Baghdadi Tareq
- Allerton Rozenn
- Allison Magnuson
- Altena Renske
- Alés Martínez Jose Enrique
- Anampa Mesias Jesus
- Andreopoulou Eleni
- Ansari Bilal
- Antill Yoland
- Aogi Kenjiro
- Aragones Antonia Marquez
- Arahmani A.
- Armstrong A.C.
- Armstrong Anne
- Armstrong Deborah
- Armstrong Deborah
- Arnedos M.
- Arrick Bradley
- Asaad Shonda
- Aydogdu Mustafa
- Baez-Diaz Luis
- Bahadur Shakeela
- Bakker Sandra
- Balmaña J.
- Barrett Sophie
- Bartsch Rupert
- Bañuelos Juan Cueva
- Bear Harry
- Bechtner Christina
- Bella Santiago
- Bergh J.
- Bermejo de las Heras Begoña
- Bernardo Antonio
- Bertrán Ana Santaballa
- Bianchini Giampaolo
- Biganzoli Laura
- Blajman Cesar
- Bliss J.
- Boadle David
- Bobolis Kristie
- Bonetti Andrea
- Bordeleau Louise
- Borges Virginia
- Borley Annabel
- Borms Marleen
- Borrego Manuel Ruiz
- Boyle L.E.
- Braga Sofia
- Brain Etienne
- Braybrooke Jeremy
- Brescia Frank
- Brufsky A.M.
- Brufsky Adam
- Bucci Eraldo
- Burhani Nafisa
- Busch Steffi
- Cameron D.
- Campbell C.
- Cannon George
- Cannon George
- Canon Jean-Luc
- Cao María González
- Cardoso Catarina
- Cardoso Fátima
- Carlson Jay
- Carlson Jay
- Carney Jennifer Fu
- Carrasco Fernando Henao
- Casa-Nova Mafalda
- Cescon Terrence
- Chacón López-Muñiz José Ignacio
- Chae Yee Soo
- Chakiba-Brugere Camille
- Chalchal Haji
- Chan Stephen
- Chang Brian
- Chang Yuan-Ching
- Charles William
- Chen Shang-Hung
- Chen Shin-Cheh
- Chen Shou-Tung
- Chiu Chang-Fang
- Cho Eun Kyung
- Chowdhury Nabila
- Chung Wei-Pang
- Ciccarese Mariangela
- Ciruelos Gil Eva María
- Cobleigh Melody
- Cole John
- Cole John
- Cole John
- Cole John
- Colleoni M.A.
- Colleoni Marco
- Company Jesús Alarcon
- Conejero Raquel Andrés
- Conibear John
- Constanzo Maria Victoria
- Conte Pierfranco
- Copson Ellen
- Copur Mehmet
- Cortesi Laura
- Cortijo Lucía González
- Cretella Elisabetta
- Cristofanilli Massimo
- Crusades Gema Llort
- Cui K.
- Curtit Elsa
- Dakhil Shaker
- Dakhil Shaker
- Dalivoust Philippe
- Darsow Maren
- Dayao Zoneddy
- de Boer Maaike
- de la Haba Juan
- de Laurentiis Michelino
- Decker Thomas
- Dedes Konstantin
- Delaloge S.
- Delaloge Suzette
- Delgado Mingorance Juan Ignacio
- Deming Richard
- Denittis Albert
- Deryal Mustafa
- Desbiens Christine
- Deveras Ruby Anne E.
- Dewar Joanna
- Dewitz Thomas
- Dieterich Max
- Domchek S.M.
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- Doster John
- Doyle Thomas
- Duhoux François
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- Eisen A.
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- Eisenberg Peter
- Ellis Robert
- Elsafy F.
- Emde Till-Oliver
- Erdkamp Franciscus
- Estevez Laura García
- Extra Jean-Marc
- Faller Bryan
- Fan Z.
- Fan Zhimin
- Fasching Peter
- Fehm Tanja
- Fein L.E.
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- Feusner James
- Fielding A.
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- Gayle Arlene
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- Hayward Richard
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- Helfgott Ruth
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- Mackiewicz Jacek
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- Martinez de Dueñas E.
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- Meisel Jane
- Menter Alex
- Merkel Douglas
- Mita Monica
- Molins Agusti Barnadas
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- Murillo Serafín Morales
- Murray Nicholas
- Müller Volkmar
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- Nagy Tünde
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- Novak Urban
- Nowecki Zbigniew
- O'Connor Brian
- Ochoa Augusto
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- Ofori Samuel
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- Oliff Ira
- Openshaw Thomas
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- Osaki Akihiko
- Padró Josep Gumà
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- Pristauz-Telsnigg Gunda
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- Ruddy Kathryn
- Ruggeri Enzo Maria
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- Sami Amer
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- Sarosiek Tomasz
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- Schmidt M.
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- Schreiber Carsten
- Seaward Samantha
- Seaward Samantha
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- Shao Z.
- Shao Zhimin
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- Sharma Priyanka
- Sharma Ruby
- Shen Kunwei
- Shenk Robert
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- Shenk Robert
- Siegel Robert
- Siggelkow Wulf
- Sigurdson Elin
- Silander Gustav
- Simon Hélène
- Simon Michael
- Singer C.F.
- Singer Christian
- Smith Ron
- Sohn Joo Hyuk
- Song Chuangui
- Sonke G.S.
- Sonke Gabe
- Soori Gamini
- Specht Jennifer
- Spector David
- Steen Preston
- Stefek Andrea
- Stickeler E.
- Stickeler Elmar
- Stockham Abigail
- Storniolo Anna M.V.
- Strasser-Weippl Kathrin
- Stöger Herbert
- Suga J. Marie
- Suga J. Marie
- Suga J. Marie
- Suga J. Marie
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- Sugimoto Takeki
- Sui Xingwei
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- Sumida Kenneth N.M.
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- Sun Qiang
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- Takada Masahiro
- Takahashi Masato
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- Tennevet Isabelle
- Terhaag Jürgen
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- Tiley Susan
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- Tokunaga Eriko
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- Tondini Carlo
- Toppmeyer Deborah
- Tormo Salvador Blanch
- Torres Antonio Antón
- Toyama Tatsuya
- Traina T.A.
- Tredan Olivier
- Trehan Shruti
- Tseng Ling-Ming
- Tsugawa Koichiro
- Tutt A.N.J.
- Tutt Andrew
- Uleer Christoph
- Unnikrishnan Madhu
- Urquhart Alexander
- Uziely Beatrice
- Vachhani Hetal
- Vakhariya Cynthia
- Valdes-Albini Frances
- van der Westhuizen Andre
- van Haelst Carol
- Vanderwoude Amy
- Varadarajan Ramya
- Varela Mirta
- Venat-Bouvet Laurence
- Verusio Claudio
- Viale G.
- Villaró Gemma Viñas
- Virani Shamsuddin
- Vogel Victor
- von Wachenfeldt Väppling Anna
- Wade James
- Wade James
- Wagner Harald
- Waisman James
- Wang Shui
- Wang Yongsheng
- Watanabe Junichiro
- Weigel Michael
- Weltermann Angsar
- Weniger Steffi
- Wette Viktor
- Wilbur Deborah
- Wilkinson Mary
- Winter Matthew
- Wolf Sütterlin Marc
- Wong Derrick
- Wong Lucas
- Wood Marie
- Wood Marie
- Woodward Natasha
- Wüllner Michaela Penelope
- Xu Binghe
- Yamauchi Hideko
- Yan Fengting
- Yanagita Yasuhiro
- Yang H.
- Yang Hongjian
- Yeh Dah-Cherng
- Yerushalmi R.
- Yerushalmi Rinat
- Yothers G.
- Yu Jyh-Cherng
- Zahm Dirk
- Zakalik Dana
- Zamagni Claudio
- Zaman Khalil
- Zarba Juan Jose
- Zera Richard
- Zera Richard
- Zhang J.
- Zhang Jin
- Zheng Hong
- Zhuo Ying
- Zimbler Harvey
- Zoppoli G.
- Öhler Leopold
- Španić T.
- Publication venue
- Elsevier
- Publication date
- 01/12/2022
- Field of study
International audienc
A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial
- Author
- Abrams Judith
- Adda Mireille
- Adderley Jane
- Adhikari Neill K. J.
- Adhikari Neill K. J.
- Aissaoui Nadia
- Alam Ahsan
- Albrett Jonathan
- Albright Robert C.
- Alcuaz Victoria
- Allam Hayat
- Altarelli Marco
- Amaral Andre
- Amsbaugh Amy
- Anderson Felicity
- Andreu Pascal
- Antunes Veronica
- Arbane Gill
- Argaud Laurent
- Arias Castro
- Asehnoune Karim
- Attwood Ben
- Auld Fiona
- Ayas Najib
- Aycinena Juan Carlos
- Azais Marie-Ange
- Bachler Mirjam
- Backhouse Felicity
- Bagshaw Sean M.
- Bagshaw Sean M.
- Bagshaw Sean M.
- Bagshaw Sean M.
- Baharlo Behrad
- Bai Guoqiang
- Bai Jing
- Baig Nadia
- Baig Nadia
- Bailey Matthew
- Baker Nerilee
- Ball Ian M.
- Ball Jonathan
- Barbar Saber Davide
- Barbier François
- Barchard Jennifer
- Bass Frances
- Bates Samantha
- Baudry Thomas
- Beck James
- Beehre Nina
- Bellemare David
- Belley-Cote Emilie
- Bellmann Romuald
- Bellomo Rinaldo
- Bellomo Rinaldo
- Benettaib Fatna
- Benoit Luc
- Benton Jane
- Benzekri Dalila
- Bergin Colin
- Bihari Shailesh
- Bihorac Azra
- Bird Sarah
- Bitker Laurent
- Board Jasmin
- Bociek Aneta
- Bohé Julien
- Boisrame-Helms Julie
- Boivin Annick
- Bojic Andja
- Bone Allison
- Boschert Catherine
- Bouisse Camille
- Boulain Thierry
- Boulet Éric
- Boumahni Dounia
- Bourchard Pierre-Alexandre
- Bowman Katie
- Bracke Stephanie
- Bradford Celia
- Brailsford Jane
- Brandtner Anna
- Bretagnol Anne
- Brickell Kathy
- Broadfield Emma
- Brodutch Shira
- Brooks Jenny
- Brown Gillian
- Brown Sherry
- Browne Troy
- Buehner Ulrike
- Buhr Heidi
- Burke Tara
- Burns Karen
- Buscher Hergen
- Butler Magdalena
- Butler Susie
- Cahill Hazel
- Cailhier Jean-François
- Callahan Jean Christophe
- Callender Owen
- Campbell Eileen
- Campbell Troy
- Campbell Victoria
- Campisi Josie
- Camporota Luigi
- Campos Sara
- Canet Emmanuel
- Cantien Marie
- Carbonnaeu Élaine
- Carles Michel
- Carney Dominic
- Carney Gayle
- Carpentier Dorothée
- Carrera Ron
- Carrier François-Martin
- Carson Joshua
- Carter Joseph
- Carungcong Jaime
- Carvelli Paula
- Cegarra Santiago
- Cennamo Armando
- Chadbourn Indra
- Chadwick Lesley
- Chan Peter
- Chee Nigel
- Chen Man
- Chen Yan
- Chen Zhenzhen
- Chenaf Samir
- Cheung Winston
- Chevrel Guillaume
- Chiella Bianca
- Chimunda Tim
- Chudeau Nicolas
- Cinotti Raphaël
- Cirone Robert
- Clarey Emma
- Clark Amy
- Clark Edward
- Clark Michele
- Clarke France
- Cleophax Cedric
- Clere-Jehl Raphael
- Cloutier Eve
- Cohen Yves
- Cole Jade
- Cole Louise
- Coles Jennifer
- Colin Gwenhaël
- Collins Amy
- Combes Alain
- Commeureuc Morgane
- Condin Christopher
- Conner Louise
- Cooper Lauren
- Corcoran Eleanor
- Costa Patricia
- Costerousse Olivier
- Coupez Elisabeth
- Cour Martin
- Cowdrey Keri-Anne
- Creary Thais
- Crosby Laura
- Cross Rosalba
- Cunningham Mishell
- Cupka Julie
- da Costa Bruno R.
- Daniels Alison
- Dargent Auguste
- Davies Tracy Michelle
- De Crop Luc
- De La Salle Sylvie
- De Prost Nicolas
- De Watteville Aude
- Decalvele Maxens
- Dechanet Aline
- Dekeyser Thibault
- Delabranche Xavier
- Delaney Anthony
- Delecolle Lucie
- Delgado Carlos Castro
- Delisle-Thibault Charles
- Demeure Dominique
- Demiri Suela
- Demoule Alexandre
- Deng Fuxing
- Derrien Benoit
- Despy Liesl
- Dessap Armand Mekontso
- Devereaux Kelson
- Di Nella Michelle
- Diehl Jean-Luc
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- Dilawershah Maria
- Ding Lili
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- D’Aragon Frédérick
- Eastwood Glenn M.
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- Elizabeth Wilcox M.
- Eller Philipp
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- Ensenyat-Martin Luis
- Eraldi Jean-Pierre
- Fadel Fouad
- Fan Jingqun
- Farnell-Ward Sarah
- Farrah Helen
- Faure Morgane
- Felix Luis
- Fellows Emma
- Fendt Lucia
- Fennessy Gerard
- Fiancette Maud
- Finfer Simon
- Finkenstedt Armin
- Finney Clare
- Fletcher Jason
- Forbes Loretta
- Forni Lui G.
- Forshaw Greg
- Foulkes Stephen
- Francoeur Charles Langis
- Franja Vincenta
- Freebairn Ross
- French Craig
- Friedrich Jan
- Fries Dietmar
- Fu Lijuan
- Fu Yongjian
- Fusco Kelly
- Gallagher Martin P.
- Gallagher Martin P.
- Gangopadhyay Himangsu
- Gantner Dashiell
- Gao Lan
- Garg Amit
- Gattas David
- Gatward Jonathan
- Gaudry Stéphane
- Gaudry Stéphane
- George Aparna
- Georgescu Ilinca
- Gernez Coralie
- Ghamraoui Ali
- Ghate Taneera
- Ghosh Angaj
- Giannakouros Panagiota
- Gibson Neil
- Giebel Shelley
- Gilder Eileen
- Glybina Anna
- Gomes Brigette
- Gomez Raquel
- Goodson Jennifer
- Gordon Boyd J.
- Goulart Joyce McKenney
- Goulart Joyce McKenney
- Goundry Stephanie
- Grainger Lia
- Grangé Steven
- Grant Alice
- Grant Caroline
- Gray Geraldine
- Grenier Stéphanie
- Gresham Rebecca
- Grillot Nicolas
- Guerot Emmanuel
- Guery Aurore
- Guilbault Gabrielle
- Guitton Christophe
- Guo Dongchen
- Guo Litao
- Gurung Babita
- Gutierrez David
- Guy Zoe
- Haljan Gregory
- Hall Adam
- Hallion Jane
- Haltia Paivi
- Hambrook Geraldine
- Hammond Naomi
- Hamshere Alexandra
- Hang Lele
- Harasemiw Oksana
- Harkett Samanth
- Harkins Margaret
- Harmon John
- Harris Claire-Louise
- Harrop Clare
- Hartig Frank
- Harvey Dan
- Hashemighouchani Haleh
- Haslam Nicole
- Hasslacher Julia
- Hauschild Caroline
- Hazelton Tracy
- He Xiandi
- He Xiaona
- Heidegger Claudia
- Heinonen Jonna
- Henderson Seton
- Henderson Steven
- Hendry Deborah
- Hernandez Clara
- Hernu Romain
- Herridge Margaret S.
- Higson Vicki
- Hill Dianne
- Hill Helen
- Hindle Julia
- Hiremath Swapnil
- Hirst Claire
- Hodder Jennifer
- Hodgson Luke E.
- Hopkins Philip
- Hoppu Sanna
- Hoste Eric
- Hou Guo
- Houghton James
- Howard Kate
- Howcroft Clare
- Howe Elizabeth
- Howlett Luisa
- Hu Chenghuan
- Hu Tingting
- Hu Xiaobo
- Huang Lili
- Huang Yingzi
- Hunt Anna
- Hunt Miranda
- Hunter Stephanie
- Hussain Nauman
- Hutch Debra
- Inkinen Outi
- Investigators STARRT-AKI
- Jackson Carolyn
- Jackson David
- Jagannathan Vijay
- Jalkanen Ville
- Jang Ryan
- Janin Pierre
- Ji Xiaojun
- Jim Kym
- Jin Xia
- Joannidis Michael
- Joannidis Michael
- Johnson Emily
- Johnston Andy
- Joseph Gipsy
- Judd Harriet
- Junge Andrea
- Järvisalo Mikko J.
- Kamel Toufik
- Kapoor Ritoo
- Karachi Tim
- Karlsson Sari
- Kashani Kianoush B.
- Kaufman Melissa
- Kaur Navjot
- Kavikondala Kanthi
- Kaye Callum
- Keet Owen
- Kentala Satu
- Kerr Deborah
- Khalid Imrana
- Ki Vincent
- Kiley Sean
- Kirkham Simon
- Kissling Sébastien
- Klein David
- Klein Sebastian
- Knight David
- Knott Cameron
- Koglberger Paul
- Kokotsis Nicos
- Kol Mark
- Koottayi Sathyajith
- Korhonen Anna-Maija
- Kruger Peter
- Kuitunen Anne
- Kummerlen Christine
- Kutsogiannis Demetrios J.
- Küllmar Mira
- Lacave Guillaume
- Lacherade Jean Claude
- Ladouceur Marilène
- Lafrance Jean-Philippe
- Lagarrigue Matthieu Henry-
- Lakatos Louis
- Lakhal Karim
- Lambert Bridget
- Lamontagne François
- Lamontagne François
- Lamontagne François
- Landais Mickael
- Landoni Giovanni
- Lapinsky Stephen
- Lappi Eliria
- Large Audrey
- Latimer-Bell Charlotte
- Latta Laura
- Laurie Gordon
- Lauzier François
- Lawrence Cassie
- Le Moal Charlène
- Leaver Susannah
- Lebert Christine
- LeBlanc Guillaume
- Lebrasseur Martine
- Lee Sandra
- Leivo Keijo
- Lellouche Francois
- Lembo Rosalba
- Lenga Ilan
- Lesona Eden
- Levoranta Markus
- Li Hao
- Li Jian
- Li Jianquan
- Li Jing
- Li Min
- Li Nan
- Li Rui
- Lian Yingtao
- Liangos Orfeas
- Licari Elisa
- Lim Rosario
- Lin Jin
- Lin Jincan
- Liu Airan
- Liu Cheng
- Liu Hongjuan
- Liu Jingfeng
- Liu Kathleen D.
- Liu Manli
- Liu Pei
- Liu Xingang
- Liu Yu
- Liu Zhongmin
- Liu Zhou
- Liu Zhuang
- Lizotte Patricia
- Lobaz Steve
- Lombardi Gaetano
- Long Dali
- Long Stephanie
- Lord Jenny
- Lowrey Julie
- Lu Kun
- Lu Liping
- Lyas Claretha
- Lynch Matthew
- Lynch Matthew
- Långsjö Jaakko
- Ma Hongye
- MacIntyre Erika
- Magder Sheldon
- Maguire Teena
- Maizel Julien
- Malila Kaisa
- Mallaird Samia Abed
- Mallet Maxime
- Manns Braden J.
- Manso Katarina
- Marceron Alina
- Marchalot Antoine
- Marchand Joannie
- Margalef Jordi
- Margarson Michael
- Marinoff Nicole
- Marios Clémence
- Marotti Martina
- Marque Sophie
- Martin Emma
- Martin-Lefevre Laurent
- Martino Frédéric
- Martins Laura
- Marzaroli Matteo
- Marzouk Mehdi
- Masi Paul
- Maslove David
- Mason Chris
- Mason Sophie
- Mason Tracy
- Masse Marie-Hélène
- Masters Kristy
- Matheson Elisha
- Mathonnet Armelle
- Mayaux Julien
- Mayette Michael
- Mazer David
- McArthur Colin
- McAuley Daniel F.
- McAuley Danny F.
- McCall Philip
- McClure Jason
- McConnochie Rachael
- McCoshen Lorena
- McCracken Phoebe
- McGain Forbes
- McGlone Philip
- McGloughlin Steve
- McGonigal Elizabeth
- McGuinness Shay
- McGuinness Shay
- McGuinness Shay P.
- McIntyre Lauralyn
- Mckay-Vucago Agnes
- McKerrow Elizabeth
- McLaughlan Derek
- Meehan Sharon
- Mehrtens Jan
- Mehta Navdeep
- Mehta Sangeeta
- Mei Huaxian
- Mei Jing
- Meng Zhaoli
- Merdji Hamid
- Meredith Megan
- Messika Jonathan
- Mew Louise
- Meyer Jason
- Meziani Ferhat
- Millen Tina
- Mitchell Wendy
- Mo Min
- Monnier Alexandra
- Monti Giacomo
- Montillier Philippe
- Moon Angela
- Mooney Owen
- Morawiec Elise
- Moreland Gayle
- Morgan Matt
- Morgan Rebecca
- Morgan Stacey
- Morizot Laura
- Morris Anna
- Moser Max
- Mu Sijie
- Mulder John
- Muller Grégoire
- Muller Lucie
- Murray Lauren
- Murray Patrick T.
- Muscedere John
- Musselwhite Janine
- Mwaura Esther
- Naeem Syed
- Naeem Syed
- Naud Jean-François
- Navarra Leanlove
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- Needham Matthew
- Neils Seigenthaller
- Newby Lynette
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- Nichol Alistair D.
- Nichol Alistair D.
- Nichol Alistair D.
- Nicholson Alice
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- Nieszkowska Ania
- Niven Alexander S.
- Niven Daniel J.
- Noble Harriet
- Noel Gibney R. T.
- Norris Sean
- Novellas Neus Grau
- Ogg Bethan
- Okubanjo Maryanne
- Olatunji Shaanti
- Omalay George
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- Orford Neil
- Ortiz-Soriano Victor M.
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- Ostermann Marlies
- Ostermann Marlies
- Ovakim Daniel
- Ovsenek Athena
- Oxtoby Kerry
- Oziemski Peter
- O’Mara AnnMarie
- O’Mara AnnMarie
- Padayachee Laven
- Palevsky Paul M.
- Pan Chun
- Pan Yu
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- Qiu Yu
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- Rahmani Imen
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- Rewa Oleksa
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- Rochwerg Bram
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- Romanovsky Adam S.
- Roodenburg Owen
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- Rosenow Nadine
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- Ruddell Stacey
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- Schenk Bettina
- Scherr Kimberly
- Schneider Antoine G.
- Schneider Antoine G.
- Schnorf Madeleine
- Schwartz Kate
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- Sharif Sairah
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- Simmonds Catherine
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- Simon Mathieu
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- Smith Orla M.
- Snelson Catherine
- Sokolowski Colleen
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- Souweine Bertrand
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- Staudinger Thomas
- Steele Andrew
- Stelfox Henry T.
- Stelfox Henry T.
- Stewart Richard
- Stoltenberg Anita
- Suen Gabriel
- Suhonen Taria
- Sun Jingjing
- Sutherland Sara-Beth
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- Thevenin Fabienne
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- Turgeon Alexis F.
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- Udy Andrew
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- Vaara Suvi T.
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- van Waegeningh Thomas
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- Vladic Chelsey
- Wagner Martin
- Walczak Karolina
- Wald Ron
- Wald Ron
- Wald Ron
- Wallace Samantha
- Wang Amanda Y.
- Wang Chuanyao
- Wang Chunting
- Wang Cunzhen
- Wang Dongxin
- Wang Haibo
- Wang Haiman
- Wang Jane
- Wang Jinlong
- Wang Kaiwu
- Wang Peng
- Wang Qizhi
- Wang Quihui
- Wang Xue
- Wang Yifeng
- Ward Geraldine
- Watpool Irene
- Watson Hayley
- Waugh Victoria
- Wax Randy
- Weir Matthew
- Weir Matthew A.
- Welsh Deborah
- Welters Ingeborg
- Wen Mingxiang
- Wetzig Krista
- White Peggy
- Whitehead Christina
- Whitehouse Tony
- Whitlock Richard P.
- Wilby Elizabeth
- Williams Erin
- Williams Karen
- Willox Fiona
- Wise Matthew
- Wittig Monika
- Wolverson Adam
- Wong Helen
- Wood Gordon
- Woolett Melissa
- Wootten Anna
- Wren Lynn
- Wu Changde
- Wu Jing
- Wun James
- Wyncoll Duncan
- Xu Hao
- Xu Song
- Yan Jie
- Yan Jinqi
- Yang Enyu
- Yang Jianxu
- Yang Juan
- Yang Yang
- Yang Yi
- Yang Ziqi
- Yao Han
- Yao Lan
- Yarad Elizabeth
- Ye Baning
- Yehia Aihem
- Young Helen
- Young Meredith
- Young Paul
- Youngs Nora
- Yu Zhui
- Zahirieh Alireza
- Zampieri Fernando G.
- Zangrillo Alberto
- Zarbock Alexander
- Zeng Qinjing
- Zhang Jichen
- Zhang Lei
- Zhang Meng
- Zhang Minwei
- Zhang Songsong
- Zhao Dan
- Zhao Mengya
- Zhao Shibing
- Zhao Shuangping
- Zhi Deyuan
- Zhou Qi
- Zhou Xiao
- Zhuang Haizhou
- Zotter Klemens
- Zuber Benjamin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
Background
Timing of initiation of kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial compared two strategies of KRT initiation (accelerated versus standard) in critically ill patients with acute kidney injury and found neutral results for 90-day all-cause mortality. Probabilistic exploration of the trial endpoints may enable greater understanding of the trial findings. We aimed to perform a reanalysis using a Bayesian framework.
Methods
We performed a secondary analysis of all 2927 patients randomized in multi-national STARRT-AKI trial, performed at 168 centers in 15 countries. The primary endpoint, 90-day all-cause mortality, was evaluated using hierarchical Bayesian logistic regression. A spectrum of priors includes optimistic, neutral, and pessimistic priors, along with priors informed from earlier clinical trials. Secondary endpoints (KRT-free days and hospital-free days) were assessed using zero–one inflated beta regression.
Results
The posterior probability of benefit comparing an accelerated versus a standard KRT initiation strategy for the primary endpoint suggested no important difference, regardless of the prior used (absolute difference of 0.13% [95% credible interval [CrI] − 3.30%; 3.40%], − 0.39% [95% CrI − 3.46%; 3.00%], and 0.64% [95% CrI − 2.53%; 3.88%] for neutral, optimistic, and pessimistic priors, respectively). There was a very low probability that the effect size was equal or larger than a consensus-defined minimal clinically important difference. Patients allocated to the accelerated strategy had a lower number of KRT-free days (median absolute difference of − 3.55 days [95% CrI − 6.38; − 0.48]), with a probability that the accelerated strategy was associated with more KRT-free days of 0.008. Hospital-free days were similar between strategies, with the accelerated strategy having a median absolute difference of 0.48 more hospital-free days (95% CrI − 1.87; 2.72) compared with the standard strategy and the probability that the accelerated strategy had more hospital-free days was 0.66.
Conclusions
In a Bayesian reanalysis of the STARRT-AKI trial, we found very low probability that an accelerated strategy has clinically important benefits compared with the standard strategy. Patients receiving the accelerated strategy probably have fewer days alive and KRT-free. These findings do not support the adoption of an accelerated strategy of KRT initiation
Regional Practice Variation and Outcomes in the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial: A Post Hoc Secondary Analysis.
- Author
- Abed Mallaird Samia
- Abrams Judith
- Adda Mireille
- Adderley Jane
- Adhikari Neill KJ
- Adhikari Neill KJ
- Adhikari Neill KJ
- Aissaoui Nadia
- Alam Ahsan
- Albrett Jonathan
- Albright Robert C
- Alcuaz Victoria
- Allam Hayat
- Altarelli Marco
- Amaral Andre
- Amsbaugh Amy
- Amélie Ordon Marie
- Anderson Felicity
- Andreu Pascal
- Antunes Veronica
- Arbane Gill
- Argaud Laurent
- Arias Castro
- Asehnoune Karim
- Attwood Ben
- Auld Fiona
- Ayas Najib
- Azais Marie-Ange
- Bachler Mirjam
- Backhouse Felicity
- Bagshaw Sean M
- Bagshaw Sean M
- Bagshaw Sean M
- Bagshaw Sean M
- Baharlo Behrad
- Bai Guoqiang
- Bai Jing
- Baig Nadia
- Baig Nadia
- Bailey Matthew
- Baker Nerilee
- Ball Ian M
- Ball Jonathan
- Barbar Davide
- Barbier François
- Barchard Jennifer
- Bass Frances
- Bates Samantha
- Baudry Thomas
- Beck James
- Beehre Nina
- Bellemare David
- Belley-Cote Emilie
- Bellmann Romuald
- Bellomo Rinaldo
- Bellomo Rinaldo
- Bellomo Rinaldo
- Benettaib Fatna
- Benoit Luc
- Benton Jane
- Benzekri Dalila
- Bergin Colin
- Bihari Shailesh
- Bihorac Azra
- Bird Sarah
- Bitker Laurent
- Board Jasmin
- Bociek Aneta
- Bohé Julien
- Boisrame-Helms Julie
- Boivin Annick
- Bojic Andja
- Bone Allison
- Boschert Catherine
- Bouisse Camille
- Boulain Thierry
- Boulet Éric
- Boumahni Dounia
- Bourchard Pierre-Alexandre
- Bowman Katie
- Bracke Stephanie
- Bradford Celia
- Brailsford Jane
- Brandtner Anna
- Bretagnol Anne
- Brickell Kathy
- Broadfield Emma
- Brodutch Shira
- Brooks Jenny
- Brown Gillian
- Brown Sherry
- Browne Troy
- Buehner Ulrike
- Buhr Heidi
- Burke Tara
- Burns Karen
- Buscher Hergen
- Butler Magdalena
- Butler Susie
- Cahill Hazel
- Cailhier Jean-François
- Callender Owen
- Campbell Eileen
- Campbell Troy
- Campbell Victoria
- Campisi Josie
- Camporota Luigi
- Campos Sara
- Canet Emmanuel
- Cantien Marie
- Carbonnaeu Élaine
- Carles Michel
- Carlos Aycinena Juan
- Carney Dominic
- Carney Gayle
- Carpentier Dorothée
- Carrera Ron
- Carrier François-Martin
- Carson Joshua
- Carter Joseph
- Carungcong Jaime
- Carvelli Paula
- Castro Delgado Carlos
- Cegarra Santiago
- Cennamo Armando
- Chadbourn Indra
- Chadwick Lesley
- Chan Peter
- Chee Nigel
- Chen Man
- Chen Yan
- Chen Zhenzhen
- Chenaf Samir
- Cheung Winston
- Chevrel Guillaume
- Chiella Bianca
- Chimunda Tim
- Christophe Callahan Jean
- Chudeau Nicolas
- Cinotti Raphaël
- Cirone Robert
- Clarey Emma
- Clark Amy
- Clark Edward
- Clark Michele
- Clarke France
- Claude Lacherade Jean
- Cleophax Cedric
- Clere-Jehl Raphael
- Cloutier Eve
- Cohen Yves
- Cole Jade
- Cole Louise
- Coles Jennifer
- Colin Gwenhaël
- Collins Amy
- Combes Alain
- Commeureuc Morgane
- Condin Christopher
- Conner Louise
- Cooper Lauren
- Corcoran Eleanor
- Costa Patricia
- Costerousse Olivier
- Coupez Elisabeth
- Cour Martin
- Cowdrey Keri-Anne
- Creary Thais
- Crosby Laura
- Cross Rosalba
- Cunningham Mishell
- Cupka Julie
- D'Aragon Frédérick
- Dang Van Hoa
- Daniels Alison
- Dargent Auguste
- De Crop Luc
- De La Salle Sylvie
- De Prost Nicolas
- De Watteville Aude
- Decalvele Maxens
- Dechanet Aline
- Dekeyser Thibault
- Delabranche Xavier
- Delaney Anthony
- Delecolle Lucie
- Delisle-Thibault Charles
- Demeure Dominique
- Demiri Suela
- Demoule Alexandre
- Deng Fuxing
- Derrien Benoit
- Despy Liesl
- Devereaux Kelson
- Di Nella Michelle
- Didier Thevenin Lens
- Diehl Jean-Luc
- Diel Naomi
- Dignam Gemma
- Dilawershah Maria
- Ding Lili
- Ding Ruiqi
- Ditlbacher Adelheid
- Dodek Peter
- Dominy Clive
- Dong Lei
- Dong Xin
- Dooley Natalie
- Doran Peter
- Dorfman Robert
- Dos Santos Sandra
- Dres Martin
- Dreyfuss Didier
- Dreyfuss Didier
- Dreyfuss Didier
- Drover John
- Du Bin
- Du Bin
- Duan Meili
- Dubos René
- Duffy Jane
- Duffy Karina
- Dufour Nicolas
- Duggan Shelley
- Duke Graeme
- Dun Shijuan
- Dyett John
- Eastwood Glenn M
- Eckert Philippe
- Efron Philip
- Elderkin Tania
- Elias Madona
- Elizabeth Wilcox M
- Ellis Karen
- Emery Malo
- Endre Zoltan
- Ensenyat-Martin Luis
- Eraldi Jean-Pierre
- Fadel Fouad
- Fan Jingqun
- Farnell-Ward Sarah
- Farrah Helen
- Faure Morgane
- Felix Luis
- Fellows Emma
- Fendt Lucia
- Fennessy Gerard
- Fiancette Maud
- Finfer Simon
- Finkenstedt Armin
- Finney Clare
- Fletcher Jason
- Forbes Loretta
- Forni Lui G
- Forshaw Greg
- Foulkes Stephen
- Franja Vincenta
- Freebairn Ross
- French Craig
- Friedrich Jan
- Fries Dietmar
- Fu Lijuan
- Fu Yongjian
- Fusco Kelly
- Gallagher Martin
- Gallagher Martin P
- Gallagher Martin P
- Gangopadhyay Himangsu
- Gantner Dashiell
- Gao Lan
- Garg Amit
- Gattas David
- Gatward Jonathan
- Gaudry Stephane
- Gaudry Stéphane
- Gaudry Stéphane
- George Aparna
- Georgescu Ilinca
- Gernez Coralie
- Ghamraoui Ali
- Ghate Taneera
- Ghosh Angaj
- Giannakouros Panagiota
- Gibson Neil
- Giebel Shelley
- Gilder Eileen
- Glybina Anna
- Gomes Brigette
- Gomez Raquel
- Goodson Jennifer
- Gordon Boyd J
- Goundry Stephanie
- Grainger Lia
- Grangé Steven
- Grant Alice
- Grant Caroline
- Grau Novellas Neus
- Gray Geraldine
- Grenier Stéphanie
- Gresham Rebecca
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- Wu Changde
- Wu Jing
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- Wyncoll Duncan
- Xu Hao
- Xu Song
- Yan Jie
- Yan Jinqi
- Yang Enyu
- Yang Jianxu
- Yang Juan
- Yang Yang
- Yang Yi
- Yang Ziqi
- Yao Han
- Yao Lan
- Yarad Elizabeth
- Ye Baning
- Yehia Aihem
- Young Helen
- Young Meredith
- Young Paul
- Youngs Nora
- Yu Zhui
- Zahirieh Alireza
- Zangrillo Alberto
- Zarbock Alexander
- Zeng Qinjing
- Zhang Jichen
- Zhang Lei
- Zhang Meng
- Zhang Minwei
- Zhang Songsong
- Zhao Dan
- Zhao Mengya
- Zhao Shibing
- Zhao Shuangping
- Zhi Deyuan
- Zhou Qi
- Zhou Xiao
- Zhuang Haizhou
- Zotter Klemens
- Zuber Benjamin
- Publication venue
- Ovid Technologies (Wolters Kluwer Health)
- Publication date
- 01/02/2024
- Field of study
ObjectivesAmong patients with severe acute kidney injury (AKI) admitted to the ICU in high-income countries, regional practice variations for fluid balance (FB) management, timing, and choice of renal replacement therapy (RRT) modality may be significant.DesignSecondary post hoc analysis of the STandard vs. Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial (ClinicalTrials.gov number NCT02568722).SettingOne hundred-fifty-three ICUs in 13 countries.PatientsAltogether 2693 critically ill patients with AKI, of whom 994 were North American, 1143 European, and 556 from Australia and New Zealand (ANZ).InterventionsNone.Measurements and main resultsTotal mean FB to a maximum of 14 days was +7199 mL in North America, +5641 mL in Europe, and +2211 mL in ANZ (p p p p p p p p = 0.007).ConclusionsAmong STARRT-AKI trial centers, significant regional practice variation exists regarding FB, timing of initiation of RRT, and initial use of continuous RRT. After adjustment, such practice variation was associated with lower ICU and hospital stay and 90-day mortality among ANZ patients compared with other regions
Identification of six new susceptibility loci for invasive epithelial ovarian cancer.
- Author
- Aalfs C M
- Aalfs Cora M
- Aben Katja K H
- Adenis Claude
- Adlard Julian
- Agata Simona
- Aghajanian Carol A
- Aghmesheh Morteza
- Agnarsson Bjarni A
- Aittomäki Kristiina
- Akloul Linda
- Alducci Elisa
- Allavena Anna
- Amor David
- Andersen Mette K
- Andrews Lesley
- Andrulis Irene L
- Antill Yoland
- Anton-Culver Hoda
- Antonenkova Natalia
- Antoniou Antonis C
- Apostolou Paraskevi
- Arason Adalgeir
- Ardern-Jones Audrey
- Ardnor Christina Edwinsdotter
- Aretini Paolo
- Armitage Shane
- Arnold Leanne
- Arnold Norbert
- Arun Banu K
- Arver Brita
- Attard Virginia
- Ausems M G E M
- Ausems Margreet G E M
- Azmi Mat Adenan Noor
- Azodi Masoud
- Bae-Jump Victoria L
- Baker Helen
- Balleine Rosemary
- Balmana Judith
- Bancroft Elizabeth
- Bandera Elisa V
- Bankier Agnes
- Bardsley Cathryn
- Barile Monica
- Barjhoux Laure
- Barkardottir Rosa B
- Barouk-Simonet Emmanuelle
- Barrowdale Daniel
- Barton David
- Barwell Julian
- Basil Jack B
- Bastick Patti
- Baumgärtner Anne
- Bean Yukie
- Becker Alexandra
- Beckmann Matthias W
- Beesley Jonathan
- Beilby John
- Belotti Muriel
- Benitez Javier
- Bennett Barbara
- Bennett Ian
- Berchuck Andrew
- Berger Andreas
- Berger Raanan
- Berlin Cheryl
- Bernard Loris
- Berry Geoffrey
- Berthet Pascaline
- Bignon Yves-Jean
- Birot Anne-Marie
- Bisogna Maria
- Bjorge Line
- Blackburn Anneke
- Blanco Ignacio
- Blank Stephanie V
- Blok M J
- Blok Marinus J
- Blom Marie-Jose
- bniak Tadeusz D
- Bogdanova Natalia
- Boggess John F
- Bogwitz Michael
- Bojesen Anders
- Bonadona Valérie
- Bonanni Bernardo
- Bonnet Françoise
- Borg Ake
- Bosch Nina
- Bourdon Violaine
- Boutry-Kryza Nadia
- Bove Betsy
- Bowtell D
- Bradshaw Nicola
- Brennan Meagan
- Bressac-de Paillerets Brigitte
- Bressac-de-Paillerets Brigitte
- Brewer Carole
- Brice Glen
- Brinton Louise A
- Bronner Myriam
- Brooks-Wilson Angela
- Brown Melissa
- Bruinsma Fiona
- Brunet Joan
- Bubien Virginie
- Buckley Michael
- Buecher Bruno
- Burgess Matthew
- Burke Jo
- Bustinza Gisela Barbany
- Butow Phyllis
- Butzow Ralf
- Buys Saundra S
- Byron John W
- Byron Keith
- Byrski Tomasz
- Caldes Trinidad
- Calender Alain
- Caligo Maria A
- Callen David
- Campbell Ian
- Capella Gabriel
- Capra Fabio
- Caron Olivier
- Carter Jonathan
- Carty Karen
- Casella Cinzia
- Castera Laurent
- Cattaneo Elisa
- Catts Zohra Ali-Kahn
- Caux-Moncoutier Virginie
- Chan Salina B
- Chan T L
- Chang-Claude Jenny
- Chauhan Deepa
- Chauhan Manisha
- Chen Ann
- Chen Xiaoqing
- Chen Zhihua
- Chenevix-Trench G
- Chiquette Jocelyne
- Christian Alice
- Chu Carol
- Chung Wendy K
- Claber Oonagh
- Claes Kathleen
- Clarke Christine
- Coetzee Gerry
- Coetzee Simon
- Cohn David E
- Colas Chrystelle
- Cole Trevor
- Collavoli Anita
- Collee J Margriet
- Collet Agnès
- Colley Alison
- Collier Rebecca
- Collonge-Rame Marie-Agnès
- Collée J M
- Concannon Patrick
- Cook Jackie
- Cook Linda S
- Cook Margaret
- Corines Marina
- Coron Fanny
- Cotton Dick
- Couch Fergus J
- Coulet Florence
- Coupier Isabelle
- Cramer Daniel W
- Crawford Gillian
- Crook Ashley
- Cui James
- Culling Bronwyn
- Cummings Margaret
- Cunningham Julie
- Cybulski Cezary
- D'Andrea Emma
- Dall'Olio Valentina
- Daly Mary B
- Damiola Francesca
- Dansonka-Mieszkowska Agnieszka
- Darder Esther
- Davidson Rosemarie
- Dawson Sarah-Jane
- de Bock G H
- de la Hoya Miguel
- de Lange J L
- De Leeneer Kim
- De Paepe Anne
- de Pauw Antoine
- deFazio A
- deFazio Anna
- Deissler Helmut
- Del Valle Jesus
- Delatycki Martin
- Delnatte Capucine
- DeMars Leslie R
- Dennis Joe
- Devilee P
- Devilee Peter
- Dicks Ed
- Dickson Rebecca
- Diez Orland
- Ding Yuan Chun
- DiSilvestro Paul A
- Ditsch Nina
- Dixon Joanne
- Dobrovic Alexander
- Doherty Jennifer A
- Dolcetti Riccardo
- Domchek Susan M
- Donaldson Alan
- Dorfling Cecilia M
- Dorkins Huw
- Douglas Fiona
- Downing Sarah
- Dreyfus Hélène
- Drummond Sarah
- du Bois Andreas
- Dudding Tracy
- Dumont Martine
- Duncan Alexis
- Dunning Alison M
- Duran Mercedes
- Durda Katarzyna
- Durell Sarah
- Dutra-Clarke Anna
- Dörk Thilo
- Dürst Matthias
- Eason Jacqueline
- Easton Douglas F
- Eccles Diana
- Eddy Charlotte
- Edkins Ted
- Edwards Robert P
- Edwards Stacey
- Eeles Ros
- Eglitis Janis
- Ehrencrona Hans
- Eilber Ursula
- Einbeigi Zakaria
- Eisenbruch Maurice
- Eisinger François
- Ejlertsen Bent
- Ekici Arif B
- Elan Camille
- Ellis Ian
- Ellis Steve
- Emanuelsson Monica
- Engel Christoph
- Engert Stefanie
- Evans D Gareth
- Faivre Laurence
- Farshid Gelareh
- Fasching Peter A
- Fassy-Colcombet Marion
- Fawcett Susan
- Feillel Viviane
- Feliubadalo Lidia
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- Feroce Irene
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- Ficarazzi Filomena
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- Fineberg Elena
- Fink-Retter Anneliese
- Fiorica James V
- Firgaira Frank
- Flanagan James
- Fleming Jean
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- Fostira Florentia
- Foulkes William D
- Fountzilas George
- Fourme Emmanuelle
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- Fournier Joëlle
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- Fridley Brooke L
- Friebel Tara
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- Ganz Patricia A
- Gao Yu-Tang
- Garber Judy
- Garcia Encarna B Gómez
- Garcia Maria Jose
- Gardner Mac
- Gattas Mike
- Gaudet Mia M
- Gauthier-Villars Marion
- Gayther Simon
- Gayther Simon A
- Gehrig Andrea
- Gentry-Maharaj Aleksandra
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- George Angela
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- Gertig D
- Gibson Sarah
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- Gismondi Viviana
- Gladieff Laurence
- Glasspool Rosalind
- Glendon Gord
- Godino Javier
- Godwin Andrew K
- Goff Sheila
- Goldblatt Jack
- Goldgar David E
- Golmard Lisa
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- Goodman Marc T
- Goodman Selina
- Gorski Bohdan
- Green Adele C
- Greene Mark H
- Greening Sian
- Gregory Helen
- Grist Scott
- Gronwald Jacek
- Guillaud-Bataille Marine
- Guimbaud Rosine
- Gómez-Garcia E B
- Haan Eric
- Hahnen Erick
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- Halliday Dorothy
- Hamann Ute
- Handallou Sandrine
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- Haque Eshika
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- Hardie Kate
- Hardouin Agnès
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- Hart Steven
- Hart Stewart
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- Hasmad Hanis Nazihah
- Hayward Nicholas K
- Hayward Nick
- Hazelett Dennis
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- Heitz Florian
- Henderson Alex
- Henriksson Karin
- Herzog Josef
- Hildebrandt Michelle A T
- Hill Kathryn
- Hillemanns Peter
- Hodgson Shirley
- Hoffman James S
- Hoffman Jonathan
- Hogdall Claus
- Hogdall Estrid
- Hogervorst F B L
- Hogervorst Frans B L
- Holland Helene
- Hollestelle Antoinette
- Hoogerbrugge Nicoline
- Hooning M J
- Hooning Maartje J
- Hopper John
- Hosono Satoyo
- Houdayer Claude
- Houghton Catherine
- Hulick Peter
- Humphrey Evelyn
- Hunt Clare
- Huo Dezheng
- Hurteau Jean A
- Huzarski Tomasz
- ichert Gabriella
- Iglesias Silvia
- Imyanitov Evgeny N
- Isaacs Claudine
- Isaccs Claudine
- Iversen Edwin S
- Izatt Louise
- Izquierdo Angel
- Jacobs Chris
- Jager Agnes
- Jakubowska Anna
- James Margaret
- James Paul
- Janavicius Ramunas
- Jaworska-Bieniek Katarzyna
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- Jenkins Mark
- Jensen Allan
- Jensen Uffe Birk
- Jernström Helena
- Ji Bu-Tian
- Jobson Irene
- Johannsson Oskar Th
- John Esther M
- Jones Alison
- Jønson Lars
- Karlan Beth Y
- Karlsson Per
- Kast Karin
- Kauff Noah
- Kaufman Bella
- Kaulich Daphne Geschwantler
- Kefford Rick
- Kelemen Linda E
- Kellar Melissa
- Kelley Joseph L
- Kemp Zoe
- Kennedy M John
- Kets C M
- Kets Carolien M
- Khan Sofia
- Kidd Alexa
- Kiely Belinda
- Kiemeney Lambertus A
- Kientz Caroline
- Kim Sung-Won
- Kirchhoff Tomas
- Kirk Judy
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- Kleibl Zdenek
- Kluijt Irma
- Knol-Bout Jacoba P
- Koehler Jessica
- Kohut Kelly
- Kollias James
- Komenaka Ian
- Konstantopoulou Irene
- Kosel Matthew
- Kovalenko Serguei
- Krakstad Camilla
- Kriege Mieke
- Kristoffersson Ulf
- Kruse Torben A
- Kuchenbaecker Karoline B
- Kupryjanczyk Jolanta
- Kwong Ava
- Laframboise Rachel
- Laitman Yael
- Lakhani Sunil
- Lalloo Fiona
- Lambo Rosanna
- Lambrechts Diether
- Lambrechts Sandrina
- Langman Caroline
- Lasa Adriana
- Lasset Christine
- Lawrenson Kate
- Lazaro Conxi
- Le Nhu D
- Leaming Amanda
- Leary Jennifer
- Lebrun Marine
- Lee Adam
- Lee Alice W
- Lee Andrew
- Lee Annette
- Lee Janet M
- Lee Jong Won
- Lee Min Hyuk
- Lefol Cédrick
- Lejbkowicz Flavio
- Lele Shashi
- Leminen Arto
- Leroux Dominique
- Lesperance Bernard
- Lester Jenny
- Lesueur Fabienne
- Levine Douglas A
- Li Qiyuan
- Liang Dong
- Liedgren Sigrun
- Ligtenberg Marjolijn J L
- Liljegren Annelie
- Lim Jacqueline
- Lin Hui-Yi
- Lin Yvonne G
- Lindblom Annika
- Lindeman Geoff
- Lindor Noralane
- Lipton Lara
- Lissowska Jolanta
- Lobb Liz
- Loman Niklas
- Longmuir Mark
- Longy Michel
- Loud Jennifer T
- Lu Karen H
- Lubinski Jan
- Lucassen Anneke
- Lundvall Lene
- Lynch Henry T
- Léone Mélanie
- Léoné Mélanie
- Ma Edmund
- Machackova Eva
- Mai Phuong L
- Male Alison
- Mann Graham
- Manoukian Siranoush
- Mariani Paolo
- Mariette Frederique
- Marsh Deborah
- Martayan Aline
- Massuger Leon F A G
- Matsuo Keitaro
- Maugard Christine
- Mazoyer Sylvie
- McBride Donna
- McCann Emma
- McGuffog Lesley
- McGuire Valerie
- McLachlan Sue Anne
- McLaughlin John R
- McLeod Diane
- McNeish Ian
- Meijers-Heijboer H E J
- Meijers-Heijboer Hanne E J
- Meindl Alfons
- Meiser Bettina
- Meldrum Cliff
- Melin Beatrice
- Melloni Giulia
- Menendez Mireia
- Menkiszak Janusz
- Menon Usha
- Mensenkamp A R
- Mensenkamp Arjen R
- Miedzybrodzka Zosia
- Milne Roger
- Miron Alex
- Mitchell Gillian
- Modugno Francesmary
- Moeller Sanne Traasdahl
- Moncoutier Virginie
- Montagna Marco
- Monteiro Alvaro N
- Morrison Patrick
- Morrison Patrick J
- Mortemousque Isabelle
- Mourits M J
- Moysich Kirsten B
- Muller Danièle
- Mulligan Anna Marie
- Muranen Taru A
- Murday Victoria
- Murray Alex
- Murray Alexandra
- Narod Steven A
- Nathanson Katherine L
- Navarro Matilde
- Nedergaard Lotte
- Nerenstone Stacy R
- Ness Roberta B
- Neuhausen Susan L
- Nevanlinna Heli
- Newman Beth
- Niederacher Dieter
- Niedermayr Eveline
- Nielsen Finn C
- Nielsen Sarah
- Nightingale Sophie
- Nikitina-Zake Liene
- Noguchi Tetsuro
- Nogues Catherine
- Nordling Margareta
- Noushmehr Houtan
- Nussbaum Robert L
- O'Connell Shona
- O'Loughlin Imelda
- O'Malley David M
- Obdeijn I M
- Odunsi Kunle
- Offit Kenneth
- Olah Edith
- Oliver Clare
- Olopade Olufunmilayo I
- Olson Sara H
- Olsson Håkan
- Olswold Curtis
- Ong Kai-ren
- Oosterwijk J C
- Oosterwijk Jan C
- Orlow Irene
- Orsulic Sandra
- Osborne Richard
- Osorio Ana
- Ottini Laura
- Overbeek L I H
- Ozcelik Hilmi
- Pachter Nick
- Page Elizabeth
- Pankratz Vernon S
- Papi Laura
- Papp Janos
- Park Sue K
- Parsons Peter G
- Pasini Barbara
- Paterson Joan
- Patrick-Miller Linda
- Patterson Briony
- Paul James
- Pearce Celeste L
- Pedersen Inge Sokilde
- Peissel Bernard
- Peixoto Ana
- Pejovic Tanja
- Pelttari Liisa M
- Pensotti Valeria
- Peock Susan
- Perkins Jo
- Permuth-Wey Jenny
- Peterlongo Paolo
- Peters Lester
- Peyrat Jean-Philippe
- Peysselon Magalie
- Pfeiler Georg
- Pharoah Paul D P
- Pharoah Paul P
- Phelan Catherine M
- Phillips Kelly
- Piedmonte Marion
- Pigg Maritta Hellström
- Pike Malcolm C
- Pilato Brunella
- Plante Marie
- Platte Radka
- Plendl Hansjoerg
- Pocza Timea
- Pohlreich Petr
- Poole Elizabeth M
- Pope Jenny
- Poppe Bruce
- Porteous Mary
- Porteous Mary E
- Preisler-Adams Sabine
- Price Melanie
- Prieur Fabienne
- Przybylo Jennifer
- Pujana Miquel Angel
- Pujol Pascal
- Purdie David M
- Purser Lynne
- Putignano Anna Laura
- Quarrell Oliver
- Radice Paolo
- Rahman Nazneen
- Ramus Susan J
- Rantala Johanna
- Rappaport Christine
- Rashid Muhammad Usman
- Rebbeck Timothy R
- Rebischung Christine
- Reeve Jeanne
- Reeve Tony
- Remenieras Audrey
- Remon Marie-Alice
- Rennert Gad
- Rhiem Kerstin
- Richards Robert
- Rickard Edwina
- Risch Harvey A
- Robinson Bridget
- Robson Mark
- Rodriguez Gustavo C
- Rogers Mark T
- Romero Atocha
- Rookus M A
- Rookus Matti A
- Rosen Barry
- Rosenquist Richard
- Rossing Mary Anne
- Rothstein Joseph H
- Rouleau Etienne
- Roversi Gaia
- Rudaitis Vilius
- Rudolph Anja
- Rudzki Barney
- Rudzki Bridget Robinson Barney
- Ruehl Ina
- Runnebaum Ingo B
- Russell N S
- Rzepecka Iwona K
- Révillion Françoise
- Salani Ritu
- Saleh Mona
- Salinas Monica
- Salisbury Elizabeth
- Salvesen Helga B
- Sambrook Joe
- Sardella Domenico
- Sarrel Kara
- Saunders Christobel
- Saunus Jodi
- Savage Sharon A
- Savarese Antonella
- Saya Sibel
- Sayer Robyn
- Schildkraut Joellen M
- Schmidt M K
- Schmutzler Rita Katharina
- Schrijver Lieske H
- Schwaab Ira
- Schwartz Peter E
- Schäfer Dieter
- Scott Clare
- Scott Elizabeth
- Scott Rodney
- Scuvera Giulietta
- Searle Anne
- Segura Pedro Perez
- Seldon Joyce
- Selkirk Christina
- Sellers Thomas A
- Senter Leigha
- Serra-Feliu Gemma
- Seshadri Ram
- Sevenet Nicolas
- Sexton Adrienne
- Seynaeve C
- Shah Sohela
- Shapira Iuliana
- Sharma Priyanka
- Sharma Raghwa
- Shelling Andrew
- Shen Howard C
- Sherman Mark E
- Shu Xiao-Ou
- Shvetsov Yurii B
- Siddiqui Nadeem
- Side Lucy
- Side Lucy E
- Sieh Weiva
- Siesling S
- Sighoko Dominique
- Simard Jacques
- Simpson Peter
- Singer Christian F
- Sinilnikova Olga
- Skytte Anne-Bine
- Slager Susan
- Small Laurie
- Smalley Sarah
- Snadden Lesley
- Snyder Carrie L
- Sobol Hagay
- Sokolenko Anna P
- Sokolowska Johanna
- Solanes Ares
- Soller Maria
- Song Honglin
- Soubrier Florent
- Soucy Penny
- Southey Melissa
- Spindler Tassja J
- Spurdle Amanda
- Stayner Barbara
- Steele Linda
- Steinemann Doris
- Stenmark-Askmalm Marie
- Stevens Kristen
- Stoppa-Lyonnet Dominique
- Sucheston Lara
- Sukiennicki Grzegorz
- Sunde Lone
- Suthers Graeme
- Sutter Christian
- Sykes Pamela
- Szabo Csilla I
- Tancredi Mariella
- Tangen Ingvild L
- Tassell Margaret
- Taylor Amy
- Taylor Donna
- Taylor Jane
- Taylor Jessica
- Taylor Natalie
- Tchatchou Sandrine
- Tea Muy-Kheng
- Teixeira Manuel R
- Tejada Maria-Isabel
- Teo Soo-Hwang
- Terry Kathryn L
- Terry Mary Beth
- Teule Alex
- Thames N E
- Thierry Benjamin
- Thomas Susan
- Thomassen Mads
- Thompson Ella
- Thompson Pamela J
- Thorne Heather
- Tibiletti Maria Grazia
- Tihomirova Laima
- Tilanus-Linthorst Madeleine A
- Timorek Agnieszka
- Tirapo Carole
- Tischkowitz Marc
- Tizzoni Laura
- Tobias Ed
- Tognazzo Silvia
- Toland Amanda Ewart
- Tollenaar R A E M
- Toloczko-Grabarek Aleksandra
- Tommasi Stefania
- Tornero Eva
- Torres Diana
- Toulas Christine
- Townshend Sharron
- Trainer Alison
- Tran Lan
- Tripathi Vishakha
- Tsai Ya-Yu
- Tucker Kathy
- Tung Nadine
- Tworoger Shelley S
- Tyler Janet
- Tyrer Jonathan
- Uhrhammer Nancy
- van Altena Anne M
- van Asperen C J
- van Asperen Christi J
- van Cronenburg T C T E F
- van den Ouweland A M W
- van den Ouweland Ans M W
- van der Baan Frederieke H
- van der Hout A H
- van der Hout Annemarie H
- van der Luijt R B
- van der Luijt Rob B
- van der Pol C C
- van Deurzen C H M
- van Deurzen Carolien H M
- van Dooren Marieke F
- Van Le Linda
- van Leeuwen F E
- van Leeuwen Flora E
- Van Nieuwenhuysen Els
- van Os T A M
- van Os Theo A M
- van Rensburg Elizabeth J
- van Roozendaal K E P
- Varesco Liliana
- Varon-Mateeva Raymonda
- Vasen H F
- Vasen Hans F A
- Vaszko Tibor
- Vaur Dominique
- Vega Ana
- Velasco Angela
- Venat-Bouvet Laurence
- Vennin Philippe
- Vergote Ignace
- Verhoef S
- Verhoef Senno
- Verloop J
- Verny-Pierre Carole
- Verp Marion
- Viel Alessandra
- Vierkant Robert A
- Vignolo-Lutati Francesca
- Vijai Joseph
- Visvader Jane
- Volorio Sara
- von Wachenfeldt Anna
- Vratimos Athanassios
- Væth Signe
- Vénat-Bouvet Laurence
- Waisfisz Q
- Waisfisz Quinten
- Wakeley Katie
- Walker Lisa
- Walker Logan
- Walpole Ian
- Walsh Christine
- Wang Chen
- Wang Xianshu
- Wang-Gohrke Shan
- Wappenschmidt Barbara
- Warcoin Mathilde
- Ward Robin
- Waring Paul
- Warner Bev
- Warren Graham
- Watt Catherine
- Weaver JoEllen
- Webb P
- Weber Bernhard H F
- Weber Rachel Palmieri
- Weitzel Jeffrey N
- Wentzensen Nicolas
- Whiteman David C
- Whittemore Alice S
- Wicklund Kristine G
- Wiggins Jennifer
- Wijnands R
- Wijnen J T
- Wijnen Juul T
- Wilkens Lynne R
- Williams Rachael
- Wilson Judy
- Winchester Lizzie
- Winship Ingrid
- Woo Yin-Ling
- Wu Anna H
- Wu Kathy
- Wu Xifeng
- Yang Hannah
- Young Mary Ann
- Zaffaroni Daniela
- Zhang Jing
- Zheng Wei
- Zheng Yonglan
- Zidan Jamal
- Zikan Michal
- Ziogas Argyrios
- Złowocka-Perłowska Elżbieta
- Öfverholm Anna
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2015
- Field of study
Effect of Antiplatelet Therapy on Survival and Organ Support–Free Days in Critically Ill Patients With COVID-19
- Author
- Abbass Hakam
- Abdeladim Lilia
- Abdelhady Hesham
- Abdelkharim Hussam
- Abdelrazik Marwa
- Abdi Zakee
- Abdukahil Sheryl Ann
- Abel Lynn
- Abraham Jacinta
- Abrahamson Gail
- Abusamra Yousuf
- Aceto Romina
- Adams Peter
- Adebambo Olumide
- Adhikari Neill
- Affleck Julia
- Agha Gloria
- Aghemo Alessio
- Agno Ronan
- Aguilar-Dano April
- Ahmad Norfaizan
- Ain Quratul
- Ainscough Kate
- Ainsworth James
- Aitken Lindianne
- Akamp Ceren
- Al Amri Ali
- Al Enezi Farhan
- Al Qasim Eman
- Al-Bassam Wisam
- Al-Beidh Farah
- Albert Martin
- Albrett Jonathan
- Alderink Bashar
- Alderman Meera
- Alegria Ana
- Alexander Brian
- Alexander Peter
- Alfonso Jordan
- Ali Farisha
- Ali Maryam
- Ali Murtaza
- Allam Hayat
- Allen Barbara
- Allen Louise
- Allibone Suzanne
- Alqahtani Samah
- Alswaidan Lolowa
- Altomy Mohammed
- Amatya Sameena
- Ambrosino Richard
- Anders Jeanette
- Anderson Thomas
- Andreae Mark
- Andric Zdravko
- Angus Derek
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Anne-Laure Fedou
- Anstey Matthew
- Antcliffe David
- Anthony Alpha
- Antoine Marchalot
- Antoine Pierre
- Antoine Studer
- Anumakonda Vikram
- Aparicio Christelle
- Apte Yogesh
- Arabi Yaseen
- Arachchige Malka
- Arbane Gill
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arias Sonia
- Arishi Hatim
- Arnold Donald
- Arnold John
- Aryal Diptesh
- Asif Namra
- Aspinwall Angelique
- Attanayaka Udara
- Attokaran Antony
- Attwood Ben
- Au Carly
- Austin Karen
- Austin Pauline
- Avard Bronwyn
- Awan Sidra
- Azaiz Amine
- Azergui Nora
- Azzaui Harun
- Babel Jakša
- Babu Suresh
- Bacon Gina
- Badalamenti Salvatore
- Badie Julio
- Bagavathy Kavitha
- Bagot Catherine
- Bagshaw Sean
- Baig Nadia
- Baikady Ravishankar
- Baillie Kenneth
- Bain William
- Baker Evelyn
- Bakthavatsalam Dhanalakshmi
- Balaie Morteza
- Bamford Amy
- Bamford Peter
- Banach Dorota
- Bannard-Smith Jonathan
- Barbash Ian
- Barbazza Leanne
- Barber Russell
- Barbier François
- Barge Deborah
- Bari Sara
- Bariola Ryan
- Barker Gareth
- Barnes Nicky
- Baron Rebecca
- Barreau Amelie
- Bart Robert
- Bartholdy Roland
- Bartley Shauna
- Barton David
- Barton Frances
- Bashyal Archana
- Basile Kim
- Bass Frances
- Bassford Christopher
- Bastola Sirjana
- Bastos Joana Margarida Pereira Sousa
- Bates Michelle
- Bates Samantha
- Batista Teresa Margarida Oliveira
- Bauchmuller Kris
- Bean Sarah
- Beane Abi
- Beard Gregory
- Beasley Richard
- Beavis Sarah
- Bedford Caroline
- Beer Deborah
- Begin Phillipe
- Begum Salma
- Bell Gillian
- Bellemare David
- Beltran Mercedes
- Bendjemar Lynda
- Benettaib Fatna
- Bensen Nicole
- Benyon Sarah
- Benzekri Dalila
- Berdaguer Fernando
- Bergin Colin
- Berry Lindsay
- Berry Scott
- Berryman Emily
- Bertel Melanie
- Best-Lane Janis
- Besten Henny
- Bevan Emily
- Bewley Jeremy
- Beyerl Ashley
- Bhagani Sanjay
- Bhandal Khushpreet
- Bhattarai Binita
- Bhimani Zahra
- Bhonagiri Deepak
- Biddie Simon
- Bihari Shailesh
- Binnie Alexandra
- Biradar Vishwanath
- Birch Janine
- Birch Jenny
- Birchall Kathrine
- Birkinshaw Isobel
- Black Ethel
- Blackledge Bethany
- Blakemore Hayley
- Bland Yvonne
- Blank Elisabeth
- Bloos Frank
- Board Jasmin
- Bocher Simon
- Bociek Aneta
- Boivin Anne-Hélène
- Bojunga Jörg
- Bone Allison
- Bonner Stephen
- Bonten Marc
- Borgatta Barbara
- Borislavova Borislava
- Borrill Zoe
- Boschert Catherine
- Bossard Isabelle
- Boulanger Marie-Claude
- Boumahni Dounia
- Bouman Angela
- Bounab Rania
- Bourgoin Charlotte
- Bourne Michelle
- Bourne Richard
- Bouvier Elodie
- Bouw-Ruiter Marianne
- Boué Yvonnick
- Bowen James
- Bowler Helen
- Boyd Craig
- Boyles Rebecca
- Bracke Stephanie
- Bradbury Charlotte
- Bradley Paul
- Brady Kara
- Brailsford Jane
- Brain Matthew
- Brajković Ana
- Brakké Karen
- Brant Emily
- Breen Patrick
- Bremmer Pamela
- Brennan Aoife
- Bretagnol Anne
- Brett Stephen
- Brewer Chris
- Brickell Kathy
- Brieger Klaus-Gerd
- Brightling Chris
- Brillinger Nicole
- Brimfield Lutece
- Brinkerhoff Gail
- Brochard Laurent
- Brohi Farooq
- Brooks Nicole
- Brown Cynthia
- Brown Louise
- Browne Troy
- Brugman Curt
- Brunetta Enrico
- Brunkhorst Frank
- Brunskill Nigel
- Bryan-Morris Kayla
- Buchanan Philip
- Budd Joanna
- Buehner Ulrike
- Buhay Megan
- Buhr Heidi
- Burbee Dylan
- Burda Dorota
- Burke David
- Burke Tara
- Burkey Jason
- Burnish Rachel
- Burns Dean
- Burns Karen
- Burrell Aidan
- Burt Karen
- Buscher Hergen
- Butler Amelia
- Butler Magdalena
- Buxton Meredith
- Buzgau Adrian
- Byrne Kathleen
- Bélteczki János
- Cabrelli Louise
- Cabreros Leilani
- Cairns Tom
- Calfee Carolyn
- Callender Owen
- Cambalova Lenka
- Campbell Andrew
- Campbell Bridget
- Campbell Lewis
- Campbell Ryan
- Campisi Josie
- Campos Sara
- Camsooksai Julie
- Caplin Cecile
- Carbonneau Frédérick
- Carmona Rosario
- Carn Vanessa
- Carpio Lillian
- Carr-Wilkinson Joanne
- Carrier François
- Carrier Marc
- Carter Brittney
- Carter David
- Carter Jay
- Casali Sherry
- Casey Ruth
- Casey Siobhan
- Castelain Vincent
- Cathcart Susanne
- Catorze Nuno José Teodoro Amaro dos Santos
- Cattelan Jessy
- Cavayas Alexandros
- Cawley Kathryn
- Cazzola Federica
- Cecconi Maurizio
- Centofanti John
- Champanerkar Shreekant
- Chan Carmen
- Chan Charles
- Chan Peter
- Chapman Marianne
- Chapman Susan
- Charles Bethan
- Charles Walton
- Charlewood Richard
- Charlton Sam
- Charron Cyril
- Chartier Delphine
- Chasse Michael
- Chassé Michaël
- Chen Yan
- Cheng Allen
- Cherian Shiney
- Cheung Winston
- Chhablani Manish
- Chukkambotla Sri
- Ciccarelli Michele
- Cirstea Emanuel
- Clair Bernard
- Clark Michele
- Clark Richard
- Clark Sarah
- Clarke Frances
- Clarke Jennifer
- Claxton Andrew
- Clement Ian
- Clere-Jehl Raphael
- Clermont Giles
- Clermont Gilles
- Cloutier Ève
- Cockrell Maeve
- Codreanu Daniel
- Coetzee Samantha
- Coghlan Phoebe
- Cole Jade
- Coles Jennifer
- Colin Gwenhael
- Collier Dawn
- Collins Amy
- Collins Daniel
- Collins Emma
- Collins Érin
- Collis Matthew
- Combaux Daniele
- Commons Robert
- Comp Susan
- Connolly Karen
- Constantini Elena
- Contou Damien
- Cook Deborah
- Cook Tim
- Cooke Jill
- Cooke Justin
- Cooper Jamie
- Cooper Josh
- Cooper Lauren
- Cooper Melanie
- Cooper Nichola
- Corbett Sarah
- Corcoran Ele
- Cornell Sarah
- Cort Jon
- Costerousse Olivier
- Couillard-Chénard Émilie
- Courtin Laura
- Coutts Amanda
- Cove Matthew
- Cowdrey Keri-Anne
- Cowley Nicholas
- Cowton Amanda
- Coyne Mark
- Craner Michelle
- Craven Thomas
- Creagh-Brown Ben
- Cremer Olaf
- Crisp Nikki
- Croft Maria
- Cruz Raulle
- Cruz Rhoze
- Cudlipp Joanna
- Cuesta Jeronimo
- Curley Gerard
- Currie Andrew
- Cusack Rebecca
- Cuthbertson Brian
- Cutler Sean
- Cviljevic Sabina
- Cárcel Sheila
- da Rocha Joana
- Daebis Admad
- Daher Rana
- Dale Katie
- Daley Jessica
- Dalton James
- Daly James
- Daly Zoe
- Daneman Nick
- Dark Paul
- Darnell Robert
- Darshana Sri
- Daugherty Jason
- Davey Miriam
- Davidson Neil
- Davies Ellie
- Davies Gwyneth
- Davies Louisa
- Davies Michelle
- Davies Rhys
- Dawda Ashlish
- Day Christopher
- de Bus Liesbet
- de Courcy-Golder Kim
- de Jong Menno
- de Jonge Evert
- de Keulenaer Adrian
- de la Fuente Carmen
- de Man Angelique
- de Neef Mark
- de Waele Jan
- Deacon Bethan
- Dean Steven
- Dean Tessa
- Dearden Joy
- Dechert William
- Declerq Pierre
- Degracia Anna
- del Prado Michael
- del Sorbo Lorenzo
- Dela Rosa Arnold
- Delaney Kirsha
- Demetriou Carrie
- Dempster Debra
- Denmade Craig
- Depuydt Pieter
- Dequin Pierre-François
- Derde Lennie
- Deshpande Kush
- Detry Michelle
- Deye Nicolas
- Dice Julie
- Digby Stephen
- Distler Michael
- Doble Patricia
- Dobson Jade
- Doherty Kaleigh
- Doherty Ronan
- Dolman Rozzie
- Donadee Chenell
- Dondrop Arjen
- Donegan Clare
- Donlon Sinead
- Donnelly Adrian
- Donnison Phil
- Doonan Reece
- Doran Peter
- Dore Rachael
- Dormand Natalie
- Dragija Lidija
- Drapola Debra
- Drayss Maria
- Driscoll Alana
- Drummond Andrew
- Drury Kay
- Duan Erick
- Duberley Stephen
- Duffy Eamon
- Duffy Oscar
- Dujardin Romein
- Duke Graeme
- Duke Zoe
- Duncan Tracy
- Dunsavage Janice
- Duplaix Mathilde
- Dushianthan Ahilanandan
- Eastgate Christine
- Ebenezer R
- Edwards Alexandra
- Effelaar Evelien
- Egreteau Pierre
- Ehrmann Stephan
- Eichenauer Dennis
- Eichinger Fred
- Ekhérian Jean-Michel
- El-Khawas Khaled
- Elender Corinna
- Elhassan Munzir
- Ellervee Anneli
- Ellis Chiara
- Ellis Christine
- Elmahi Einas
- Elsefi Tarek
- Eltayeb Ayaa
- Elvira Evangeline
- English Shane
- Epelman Slava
- Eroglu Ege
- Estcourt Lise
- Estensen Kristen
- Evans Andrew
- Evans Debra
- Everitt Robert
- Evers Mirjam
- Evetts George
- Ewalds Esther
- Fagan Laura
- Fagbodun Elizabeth
- Farahi Neda
- Farnell-Ward Sarah
- Fartoukh Muriel
- Faulkner Beverley
- Faulkner Maria
- Fazekas Ágnes
- Felton Tim
- Fennessy Gerard
- Ferguson Niall
- Ferguson Susan
- Fergusson Dean
- Fernandez Maria
- Fernando Gloria
- Fernández de Pinedo Artaraz Ziortza
- Ferreira Ricardo Manuel Castro
- Ferrier Janet
- Ferringer Cindy
- Fesz Jessica
- Fierens Jan
- Finch Cheryl
- Finn André
- Finn Stephanie
- Fischer Roy
- Fitzgerald Mark
- Fitzpatrick Meghan
- Fletcher Simon
- Flint Neil
- Flor Thomas
- Florescu Simin
- Folci Marco
- Forbes Andrew
- Forbes Loretta
- Ford Megan
- Forster Elliot
- Fortune Louise
- Foster Tracy
- Fottrell-Gould Deirdre
- Foulds Angela
- Fowler Rob
- Fowler Robert
- Fox Claire
- Fox Eleonore
- Fragner Gertrud
- Frakking Thuy
- Francoeur François
- Francois Bruno
- Frankfurter Claudia
- Franz Christopher
- François Bourgerol
- Frater Alasdair
- French Craig
- Frey Anna
- Frey Christian
- Frise Matthew
- Fuchs Ralph
- Fysh Ed
- Gachet Alexandre
- Galea James
- Ganesan Arunkumar
- Ganesan Manisha
- Ganguly Saibal
- Garcia Sara
- Gardiner-Hill Caroline
- Garot Denis
- Garrard Hywel
- Garrard William
- Garrett Peter
- Garton Mark
- Gascoyne Rachel
- Gattas David
- Gauli Basanta
- Gay Alexandra
- Gaylard Jane
- Gellamucho Minerva
- Gemmell Lisa
- Gendall Emma
- Geng Wenli
- Geoghegan Pierce
- Geri Guillaume
- Geurts Heidi
- Ghaffari Mehrdad
- Ghamraoui Ali
- Ghattaoraya Amardeep
- Ghosh Alison
- Gill Mandy
- Gilliam Matthew
- Girard Timothy
- Gladas Kirsty
- Glasby Kathleen
- Gledhill Lisa
- Gluck Samuel
- Goddard Wendy
- Godement Mathieu
- Goebeler M.E.
- Golden David
- Goldman John
- Goligher Ewan
- Gomez Keith
- Gommans Frank
- Goodson Jennifer
- Goossens Herman
- Gopal Shameer
- Gopinath Amitha
- Goralski Patricia
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- Winters Lauren
- Wise Matt
- Wiseman Sophie
- Wisniewski Mary
- Wittenberg Wendy
- Wnuk Chris
- Woelke Amy
- Wong Helen
- Wong Onyee
- Wood Erica
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wrey Brown Caroline
- Wright Chris
- Wunderley Renee
- Wyatt Rachel
- Wylie Katharine
- Xavier Kugan
- Yang Yang
- Yarad Elizabeth
- Yates David
- Yealy Donald
- Young Chelsea
- Young Ian
- Young Meredith
- Young Paul
- Youngstein Taryn
- Yu Haili
- Yusuff Hakeem
- Zaharia Mihaela
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zammit Claire
- Zapalac Marija
- Zarychanski Ryan
- Zhao Xiao
- Zinzoni Vanessa
- Zitter Letizia
- Zouita Louisa
- Đimoti Renata
- Publication venue
- American Medical Association
- Publication date
- 05/04/2022
- Field of study
International audienc
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
- Author
- Abdel-Aziz Amal Kamal
- Abdelfatah Sara
- Abdellatif Mahmoud
- Abdoli Asghar
- Abel Steffen
- Abeliovich Hagai
- Abildgaard Marie H
- Abudu Yakubu Princely
- Acevedo-Arozena Abraham
- Adamopoulos Iannis E
- Adeli Khosrow
- Adolph Timon E
- Adornetto Annagrazia
- Aflaki Elma
- Afshar Elham Ghasemipour
- Agam Galila
- Agarwal Anupam
- Aggarwal Bharat B
- Agnello Maria
- Agostinis Patrizia
- Agrewala Javed N
- Agrotis Alexander
- Aguilar Patricia V
- Ahmad S Tariq
- Ahmed Zubair M
- Ahumada-Castro Ulises
- Aits Sonja
- Aizawa Shu
- Akkoc Yunus
- Akoumianaki Tonia
- Akpinar Hafize Aysin
- Al-Abd Ahmed M
- Al-Akra Lina
- Al-Bari M Abdul Alim
- Al-Gharaibeh Abeer
- Alaoui-Jamali Moulay A
- Alberti Simon
- Alcocer-Gomez Elisabet
- Alcon Soledad Porte
- Alessandri Cristiano
- Ali Muhammad
- Aliwaini Saeb
- Alizadeh Javad
- Almacellas Eugenia
- Almasan Alexandru
- Alonso Alicia
- Alonso Guillermo D
- Altan-Bonnet Nihal
- Altieri Dario C
- Alvarez Elida MC
- Alves Sara
- Alzaharna Mazen M
- Amadio Marialaura
- Amantini Consuelo
- Amaral Cristina
- Ambrosio Susanna
- Amer Amal O
- Ammanathan Veena
- An Zhenyi
- Andersen Stig U
- Andrabi Shaida A
- Andrade-Silva Magaiver
- Andres Allen M
- Angelini Sabrina
- Ann David
- Anozie Uche C
- Ansari Mohammad Y
- Antas Pedro
- Antebi Adam
- Anton Zurine
- Anwar Tahira
- Apetoh Lionel
- Apostolova Nadezda
- Araki Toshiyuki
- Araki Yasuhiro
- Arasaki Kohei
- Araujo Thais Fenz
- Araujo Wagner L
- Araya Jun
- Arden Catherine
- Arevalo Maria-Angeles
- Arguelles Sandro
- Arias Esperanza
- Arikkath Jyothi
- Arimoto Hirokazu
- Ariosa Aileen R
- Armstrong-James Darius
- Arnaune-Pelloquin Laetitia
- Aroca Angeles
- Arroyo Daniela S
- Arsov Ivica
- Artero Ruben
- Asaro Dalia Maria Lucia
- Aschner Michael
- Ashrafizadeh Milad
- Ashur-Fabian Osnat
- Atanasov Atanas G
- Au Alicia K
- Auberger Patrick
- Auner Holger W
- Aurelian Laure
- Autelli Riccardo
- Avagliano Laura
- Avalos Yenniffer
- Aveic Sanja
- Aveleira Celia Alexandra
- AvinWittenberg Tamar
- Aydin Yucel
- Ayton Scott
- Ayyadevara Srinivas
- Azzopardi Maria
- Baba Misuzu
- Backer Jonathan M
- Backues Steven K
- Bae Dong-Hun
- Bae Ok-Nam
- Bae Soo Han
- Baehrecke Eric H
- Baek Ahruem
- Baek Seung-Hoon
- Baek Sung Hee
- Bagetta Giacinto
- Bagniewska-Zadworna Agnieszka
- Bai Hua
- Bai Jie
- Bai Xiyuan
- Bai Yidong
- Bairagi Nandadulal
- Baksi Shounak
- Balazadeh Salma
- Balbi Teresa
- Baldari Cosima T
- Balduini Walter
- Ballabio Andrea
- Ballester Maria
- Balzan Rena
- Bandopadhyay Rina
- Banerjee Sreeparna
- Banerjee Sulagna
- Bao Yan
- Baptista Mauricio S
- Baracca Alessandra
- Barbati Cristiana
- Bargiela Ariadna
- Barila Daniela
- Barlow Peter G
- Barmada Sami J
- Barreiro Esther
- Barrera Miguel Calvo-Rubio
- Barreto George E
- Bartek Jiri
- Bartel Bonnie
- Bartolome Alberto
- Barve Gaurav R
- Basagoudanavar Suresh H
- Bassham Diane C
- Basu Alakananda
- Batoko Henri
- Batten Isabella
- Baulieu Etienne E
- Baumgarner Bradley L
- Bayry Jagadeesh
- Beale Rupert
- Beau Isabelle
- Beaumatin Florian
- Bechara Luiz RG
- Beck George R Jr
- Beers Michael F
- Begun Jakob
- Behl Christian
- Behrends Christian
- Behrens Georg MN
- Bei Roberto
- Bejarano Eloy
- Bel Shai
- Belaid Amine
- Belgareh-Touze Naima
- Bellarosa Cristina
- Belleudi Francesca
- Bello Perez Melissa
- Bello-Morales Raquel
- Beltran Sebastian
- Benbrook Doris Mangiaracina
- Bendorius Mykolas
- Benitez Bruno A
- Benito-Cuesta Irene
- Bensalem Julien
- Berchtold Martin W
- Berezowska Sabina
- Bergamaschi Daniele
- Bergami Matteo
- Bergmann Andreas
- Berliocchi Laura
- Berlioz-Torrent Clarisse
- Bernard Amelie
- Berthoux Lionel
- Besirli Cagri G
- Besteiro Sebastien
- Betin Virginie M
- Beyaert Rudi
- Bezbradica Jelena S
- Bharath MM Srinivas
- Bhaskar Kiran
- Bhatia-Kissova Ingrid
- Bhattacharya Resham
- Bhattacharya Sujoy
- Bhattacharyya Shalmoli
- Bhuiyan Md Shenuarin
- Bhutia Sujit Kumar
- Bi Lanrong
- Bi Xiaolin
- Biden Trevor J
- Bijian Krikor
- Billes Viktor A
- Binart Nadine
- Bincoletto Claudia
- Birgisdottir Asa B
- Bjorkoy Geir
- Blanco Gonzalo
- Blas-Garcia Ana
- Blasiak Janusz
- Blomgran Robert
- Blomgren Klas
- Blum Janice S
- Boada-Romero Emilio
- Boban Mirta
- BoeszeBattaglia Kathleen
- Boeuf Philippe
- Boland Barry
- Bomont Pascale
- Bonaldo Paolo
- Bonam Srinivasa Reddy
- Bonfili Laura
- Bonifacino Juan S
- Boone Brian A
- Bootman Martin D
- Bordi Matteo
- Borner Christoph
- Bornhauser Beat C
- Borthakur Gautam
- Bosch Jurgen
- Bose Santanu
- Botana Luis M
- Botas Juan
- Boulanger Chantal M
- Boulton Michael E
- Bourdenx Mathieu
- Bourgeois Benjamin
- Bourke Nollaig M
- Bousquet Guilhem
- Boya Patricia
- Bozhkov Peter V
- Bozi Luiz HM
- Bozkurt Tolga O
- Brackney Doug E
- Brand-Saberi Beate
- Brandts Christian H
- Braun Ralf J
- Braus Gerhard H
- Bravo-Sagua Roberto
- Bravo-San Pedro Jose M
- Brest Patrick
- Bringer Marie-Agnes
- Briones-Herrera Alfredo
- Broaddus V Courtney
- Brodersen Peter
- Brodsky Jeffrey L
- Brody Steven L
- Bronson Paola G
- Bronstein Jeff M
- Brown Carolyn N
- Brown Rhoderick E
- Brum Patricia C
- Brumell John H
- Brunetti-Pierri Nicola
- Bruno Daniele
- Bryson-Richardson Robert J
- Bucci Cecilia
- Buch Shilpa
- Buchan J Ross
- Buchrieser Carmen
- Buckingham Erin M
- Budak Hikmet
- Budini Mauricio
- Bueno Marta
- Buitrago-Molina Laura Elisa
- Bultynck Geert
- Burada Florin
- Buraschi Simone
- Burgoyne Joseph R
- Buron M Isabel
- Bustos Victor
- Buttner Sabrina
- Butturini Elena
- Byrd Aaron
- Cabas Isabel
- Cabrera-Benitez Sandra
- Cadwell Ken
- Cai Jingjing
- Cai Lu
- Cai Qian
- Cairo Montserrat
- Calbet Jose A
- Caldwell Guy A
- Caldwell Kim A
- Call Jarrod A
- Calvani Riccardo
- Calvo Ana C
- Camara Niels Os
- Camonis Jacques H
- Camougrand Nadine
- Campanella Michelangelo
- Campbell Edward M
- Campbell-Valois Francois-Xavier
- Campello Silvia
- Campesi Ilaria
- Campos Juliane C
- Camuzard Olivier
- Cancino Jorge
- Canesi Laura
- Caniggia Isabella
- Canonico Barbara
- Canti Carles
- Cao Bin
- Caraglia Michele
- Carames Beatriz
- Carchman Evie H
- Cardenal-Munoz Elena
- Cardenas Cesar
- Cardenas Luis
- Cardoso Sandra M
- Carew Jennifer S
- Carle Georges F
- Carleton Gillian
- Carloni Silvia
- Carmona-Gutierrez Didac
- Carneiro Leticia A
- Carnevali Oliana
- Carosi Julian M
- Carra Serena
- Carrier Alice
- Carrier Lucie
- Carroll Bernadette
- Carter A Brent
- Carvalho Andreia Neves
- Casanova Magali
- Casas Caty
- Casas Josefina
- Cassioli Chiara
- Castillo Eliseo F
- Castillo Karen
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- Castoldi Francesca
- Castori Marco
- Castro Ariel F
- Castro-Caldas Margarida
- Castro-Hernandez Javier
- Castro-Obregon Susana
- Catz Sergio D
- Cavadas Claudia
- Cavaliere Federica
- Cavallini Gabriella
- Cavinato Maria
- Cayuela Maria L
- Cecarini Valentina
- Cecconi Francesco
- Cechowska-Pasko Marzanna
- Cenci Simone
- Ceperuelo-Mallafre Victoria
- Cerqueira Joao J
- Cerutti Janete M
- Cervia Davide
- Cetintas Vildan Bozok
- Cetrullo Silvia
- Chae Han-Jung
- Chagin Andrei S
- Chai Chee-Yin
- Chakrabarti Gopal
- Chakrabarti Oishee
- Chakraborty Tapas
- Chakraborty Trinad
- Chami Mounia
- Chamilos Georgios
- Chan David W
- Chan Edmond YW
- Chan Edward D
- Chan Helen H
- Chan Hung
- Chan HY Edwin
- Chan Matthew TV
- Chan Yau Sang
- Chandra Partha K
- Chang Chih-Peng
- Chang Chunmei
- Chang Hao-Chun
- Chang Kai
- Chao Jie
- Chapman Tracey
- Charlet-Berguerand Nicolas
- Chatterjee Samrat
- Chaube Shail K
- Chaudhary Anu
- Chauhan Santosh
- Chaum Edward
- Cheallaigh Cliona Ni
- Checler Frederic
- Cheetham Michael E
- Chen ChangShi
- Chen Guang-Chao
- Chen Jian-Fu
- Chen Leilei
- Chen Liam L
- Chen Lin
- Chen Mingliang
- Chen MuKuan
- Chen Ning
- Chen Quan
- Chen Ruey-Hwa
- Chen Shi
- Chen Wei
- Chen Weiqiang
- Chen XinMing
- Chen Xiong-Wen
- Chen Xu
- Chen Yan
- Chen Ye-Guang
- Chen Yingyu
- Chen Yongqiang
- Chen Yue-Qin
- Chen YuJen
- Chen Zhefan Stephen
- Chen Zhi
- Chen Zhi-Hua
- Chen Zhijian J
- Chen Zhixiang
- Chen Zhong
- Cheng Hanhua
- Cheng Jun
- Cheng Shi-Yuan
- Cheng Wei
- Cheng Xiaodong
- Cheng Xiu-Tang
- Cheng Yiyun
- Cheng Zhiyong
- Cheong Heesun
- Cheong Jit Kong
- Chernyak Boris V
- Cherry Sara
- Cheung Chi Fai Randy
- Cheung Chun Hei Antonio
- Cheung King-Ho
- Chevet Eric
- Chi Richard J
- Chiang Alan Kwok Shing
- Chiaradonna Ferdinando
- Chiarelli Roberto
- Chiariello Mario
- Chica Nathalia
- Chiocca Susanna
- Chiong Mario
- Chiou Shih-Hwa
- Chiramel Abhilash I
- Chiurchiu Valerio
- Cho Dong-Hyung
- Choe Seong-Kyu
- Choi Augustine MK
- Choi Mary E
- Choudhury Kamalika Roy
- Chow Norman S
- Chu Charleen T
- Chua Jason P
- Chua John Jia En
- Chung Hyewon
- Chung Kin Pan
- Chung Seockhoon
- Chung So-Hyang
- Chung Yuen-Li
- Cianfanelli Valentina
- Ciechomska Iwona A
- Cifuentes Mariana
- Cinque Laura
- Cirak Sebahattin
- Cirone Mara
- Clague Michael J
- Clarke Robert
- Clementi Emilio
- Coccia Eliana M
- Codogno Patrice
- Cohen Ehud
- Cohen Mickael M
- Colasanti Tania
- Colasuonno Fiorella
- Colbert Robert A
- Colell Anna
- Coll Nuria S
- Collins Mark O
- Colombo Maria I
- Colon-Ramos Daniel A
- Combaret Lydie
- Comincini Sergio
- Cominetti Marcia R
- Compagnoni Giacomo Monzio
- Consiglio Antonella
- Conte Andrea
- Conti Fabrizio
- Contu Viorica Raluca
- Cookson Mark R
- Coombs Kevin M
- Coppens Isabelle
- Corasaniti Maria Tiziana
- Cordes Nils
- Corkery Dale P
- Cortese Katia
- Costa Maria do Carmo
- Costantino Sarah
- Costelli Paola
- Coto-Montes Ana
- Crack Peter J
- Crespo Jose L
- Criollo Alfredo
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- Cui Bing
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- Culetto Emmanuel
- Cumino Andrea C
- Cybulsky Andrey V
- Czaja Mark J
- Czuczwar Stanislaw J
- D'Adamo Stefania
- D'Amelio Marcello
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- D'Lugos Andrew C
- D'Orazi Gabriella
- da Costa Cristine Alves
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- Das Hiranmoy
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- Dasari Santosh K
- Dash Srikanta
- Daumke Oliver
- Dauphinee Adrian N
- Davies Jeffrey S
- Davila Valeria A
- Davis Roger J
- Davis Tanja
- de Almeida Danilo Candido
- de Almeida Luis Pereira
- De Amicis Francesca
- de Andrade Ramos Bruna Ribeiro
- De Bosscher Karolien
- De Felice Francesca
- De Franceschi Lucia
- De Leonibus Chiara
- de Mattos Barbosa Mayara G
- De Meyer Guido RY
- De Milito Angelo
- De Nunzio Cosimo
- de Oliveira Beltran Jackeline Soares
- De Palma Clara
- De Santi Mauro
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- De Zio Daniela
- Debnath Jayanta
- DeBosch Brian J
- Decuypere JeanPaul
- Deehan Mark A
- Deflorian Gianluca
- DeGregori James
- Dehay Benjamin
- Del Rio Gabriel
- Delaney Joe R
- Delbridge Lea MD
- Delorme-Axford Elizabeth
- Delpino M Victoria
- Demarchi Francesca
- Dembitz Vilma
- Demers Nicholas D
- Deng Hongbin
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- Dent Paul
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- Der Channing J
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- Di Guglielmo Gianni M
- Di Leo Luca
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- Diao Jiajie
- Diaz-Araya Guillermo
- Diaz-Laviada Ines
- Dickinson Jared M
- Diederich Marc
- Dieude Melanie
- Dikic Ivan
- Ding Shiping
- Ding Wen-Xing
- Dini Luciana
- Dinic Miroslav
- Dinkova-Kostova Albena T
- Dionne Marc S
- Distler Jorg HW
- Diwan Abhinav
- Dixon Ian MC
- Djavaheri-Mergny Mojgan
- Dobrinski Ina
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- Dou Huan
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- Duan Shao-Bin
- Duan Xiaoqiong
- Duarte Sonia P
- Dubrovska Anna
- Dunlop Elaine A
- Dupont Nicolas
- Duran Raul V
- Dwarakanath Bilikere S
- Dyshlovoy Sergey A
- Ebrahimi-Fakhari Darius
- Eckhart Leopold
- Edelstein Charles L
- Efferth Thomas
- Eftekharpour Eftekhar
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- Eissa N Tony
- Eissa Sanaa
- Ejarque Miriam
- El Andaloussi Abdeljabar
- El-Hage Nazira
- El-Naggar Shahenda
- El-Shafey Eman S
- Eleuteri Anna Maria
- Elgendy Mohamed
- Eliopoulos Aristides G
- Elizalde Maria M
- Elks Philip M
- Elsasser Hans-Peter
- Elsherbiny Eslam S
- Emerling Brooke M
- Emre NC Tolga
- Emre Serap Dokmeci
- Eng Christina H
- Engedal Nikolai
- Engelbrecht Anna-Mart
- Engelsen Agnete ST
- Enserink Jorrit M
- Escalante Ricardo
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- Fadeel Bengt
- Fader Claudio
- Faesen Alex C
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- Falco Alberto
- Falkenburger Bjorn H
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- Fang Yanshan
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- Faure Mathias
- Fazeli Gholamreza
- Fedele Anthony O
- Feldman Arthur M
- Feng Du
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- Fernandez Alvaro F
- Fernandez-Checa Jose C
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- Fernie Alisdair R
- Ferrante Anthony W Jr
- Ferraresi Alessandra
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- Finetti Francesca
- Finkbeiner Steven
- Fisher Edward A
- Fisher Paul B
- Flamigni Flavio
- Fliesler Steven J
- Flo Trude H
- Florance Ida
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- Fon Edward A
- Forlino Antonella
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- Frankel Lisa B
- Friedman Scott L
- Frohlich Leopold F
- Fruhbeck Gema
- Fuentes Jose M
- Fujiki Yukio
- Fujita Naonobu
- Fujiwara Yuuki
- Fukuda Mitsunori
- Fulda Simone
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- Furuya Norihiko
- Fusco Carmela
- Gack Michaela U
- Gaffke Lidia
- Galadari Sehamuddin
- Galasso Alessia
- Galindo Maria F
- Galluzzi Lorenzo
- Galy Vincent
- Gammoh Noor
- Gan Boyi
- Ganley Ian G
- Gao Feng
- Gao Hui
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- Gao Ping
- Gao Shou-Jiang
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- Garcera Ana
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- Garg Abhishek D
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- Gassen Nils C
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- Gewirtz David A
- Ghavami Saeid
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- Gibson Gary E
- Gibson Spencer B
- Ginet Vanessa
- Giniger Edward
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- Girao Henrique
- Girardin Stephen E
- Giridharan Mridhula
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- Golebiewska Anna
- Gomes Luciana R
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- Gomez-Sanchez Ruben
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- Gong Qingqiu
- Goni Felix M
- Gonzalez-Gallego Javier
- Gonzalez-Hernandez Tomas
- Gonzalez-Polo Rosa A
- Gonzalez-Reyes Jose A
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- Goping Ing Swie
- Gorbatyuk Marina S
- Gorbunov Nikolai V
- Gorojod Roxana M
- Gorski Sharon M
- Goruppi Sandro
- Gotor Cecilia
- Gottlieb Roberta A
- Gozes Illana
- Gozuacik Devrim
- Graef Martin
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- Granatiero Veronica
- Grasso Daniel
- Gray Joshua P
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- Greenhough Alexander
- Gregory Stephen L
- Griffin Edward F
- Grinstaff Mark W
- Gros Frederic
- Grose Charles
- Gross Angelina S
- Gruber Florian
- Grumati Paolo
- Grune Tilman
- Gu Xueyan
- Guan Jun-Lin
- Guardia Carlos M
- Guda Kishore
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- Gunst Jan
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- Guntur Anyonya R
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- Gupta Swapnil
- Gupta Veer Bala
- Gupta Vivek
- Gustafsson Asa B
- Gutterman David D
- Haapasalo Annakaisa
- Haber James E
- Hadano Shinji
- Hafren Anders J
- Haidar Mansour
- Hall Belinda S
- Hallden Gunnel
- Hamacher-Brady Anne
- Hamann Andrea
- Hamasaki Maho
- Han Weidong
- Hansen Malene
- Hanson Phyllis I
- Hao Zijian
- Harada Masaru
- Harhaji-Trajkovic Ljubica
- Hariharan Nirmala
- Haroon Nigil
- Harris James
- Hasegawa Takafumi
- Haspel Jeffrey A
- Haucke Volker
- Hawkins Wayne D
- Hay Bruce A
- Haynes Cole M
- Hayrabedyan Soren B
- Hays Thomas S
- He Congcong
- He Qin
- He RongRong
- He You-Wen
- He Yu-Ying
- Heakal Yasser
- Heberle Alexander M
- Hejtmancik J Fielding
- Helgason Gudmundur Vignir
- Henkel Vanessa
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- Herpin Amaury
- Herreros Judit
- Hervas Javier H
- Hesselson Daniel
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- Priault Muriel
- ProikasCezanne Tassula
- Promponas Vasilis J
- Proud Christopher G
- Puertollano Rosa
- Puglielli Luigi
- Pulinilkunnil Thomas
- Puri Deepika
- Puri Rajat
- Puyal Julien
- Qi Xiaopeng
- Qi Yongmei
- Qian Wenbin
- Qiang Lei
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- Quadrilatero Joe
- Quarleri Jorge
- Raben Nina
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- Rahimi Nader
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- Ramsden David B
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- Rangarajan Pundi N
- Ranieri Danilo
- Ranjitha HB
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- Razani Babak
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- Regnier-Vigouroux Anne
- Reichert Andreas S
- Reigada David
- Reiling Jan H
- Rein Theo
- Reipert Siegfried
- Rekha Rokeya Sultana
- Ren Hongmei
- Ren Jun
- Ren Weichao
- Renault Tristan
- Renga Giorgia
- Reue Karen
- Rewitz Kim
- Riazuddin S Amer
- Ribeiro-Rodrigues Teresa M
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- Risbud Makarand V
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- Roccheri Maria Carmela
- Rocchi Stephane
- Rodney George G
- Rodrigues Silva Vagner Ramon
- Rodrigues Tiago
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- Rodriguez-Barrueco Ruth
- Rodriguez-Henche Nieves
- Rodriguez-Rocha Humberto
- Roelofs Jeroen
- Rogers Robert S
- Rogov Vladimir V
- Rojo Ana I
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- Rosenwald Anne G
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- Vega-Rubin-de-Celis Silvia
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- Velasco Guillermo
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- Vellai Tibor
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- Velotti Francesca
- Verdier Mireille
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- Villalobo Antonio
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- Wang Hexiang
- Wang Hong-Gang
- Wang Jianrong
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- Wang Jundong
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- Wang Maggie Haitian
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- Wang Pengwei
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- Wang Yipeng
- Wang Yu
- Wang Yuqi
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- Wu Junfang
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- Wu Shan-Ying
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- Xiang Jin
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- Xiang Wei
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- Xiao Guozhi
- Xiao Hengyi
- Xiao Hong-tao
- Xiao Jian
- Xiao Lan
- Xiao Shi
- Xiao Yin
- Xie Baoming
- Xie Chuan-Ming
- Xie Min
- Xie Yuxiang
- Xie Zhiping
- Xie Zhonglin
- Xilouri Maria
- Xu Congfeng
- Xu En
- Xu Haoxing
- Xu Jing
- Xu JinRong
- Xu Liang
- Xu Wen Wen
- Xu Xiulong
- Xue Yu
- Yakhine-Diop Sokhna MS
- Yamaguchi Masamitsu
- Yamaguchi Osamu
- Yamamoto Ai
- Yamashina Shunhei
- Yan Shengmin
- Yan Shian-Jang
- Yan Zhen
- Yanagi Yasuo
- Yang Chuanbin
- Yang Dun-Sheng
- Yang Huan
- Yang Huang-Tian
- Yang Hui
- Yang Jin-Ming
- Yang Jing
- Yang Jingyu
- Yang Ling
- Yang Liu
- Yang Ming
- Yang Pei-Ming
- Yang Qian
- Yang Seungwon
- Yang Shu
- Yang Shun-Fa
- Yang Wannian
- Yang Wei Yuan
- Yang Xiaoyong
- Yang Xuesong
- Yang Yi
- Yang Ying
- Yao Honghong
- Yao Shenggen
- Yao Xiaoqiang
- Yao Yong-Gang
- Yao Yong-Ming
- Yasui Takahiro
- Yazdankhah Meysam
- Yen Paul M
- Yi Cong
- Yin Xiao-Ming
- Yin Yanhai
- Yin Zhangyuan
- Yin Ziyi
- Ying Meidan
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- Yiu Stephanie Pei Tung
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- Yoshida Kiyotsugu
- Yoshii Saori R
- Yoshimori Tamotsu
- Yousefi Bahman
- Yu Boxuan
- Yu Haiyang
- Yu Jun
- Yu Jun
- Yu Li
- Yu Ming-Lung
- Yu Seong-Woon
- Yu Victor C
- Yu W Haung
- Yu Zhengping
- Yu Zhou
- Yuan Junying
- Yuan Ling-Qing
- Yuan Shilin
- Yuan Shyng-Shiou F
- Yuan Yanggang
- Yuan Zengqiang
- Yue Jianbo
- Yue Zhenyu
- Yun Jeanho
- Yung Raymond L
- Zacks David N
- Zaffagnini Gabriele
- Zambelli Vanessa O
- Zanella Isabella
- Zang Qun S
- Zanivan Sara
- Zappavigna Silvia
- Zaragoza Pilar
- Zarbalis Konstantinos S
- Zarebkohan Amir
- Zarrouk Amira
- Zeitlin Scott O
- Zeng Jialiu
- Zeng Ju-deng
- Zerovnik Eva
- Zhan Lixuan
- Zhang Bin
- Zhang Donna D
- Zhang Hanlin
- Zhang Hong
- Zhang Hong
- Zhang Honghe
- Zhang Huafeng
- Zhang Huaye
- Zhang Hui
- Zhang Hui-Ling
- Zhang Jianbin
- Zhang Jianhua
- Zhang Jing-Pu
- Zhang Kalin YB
- Zhang Leshuai W
- Zhang Lin
- Zhang Lisheng
- Zhang Lu
- Zhang Luoying
- Zhang Menghuan
- Zhang Peng
- Zhang Sheng
- Zhang Wei
- Zhang Xiangnan
- Zhang Xiao-Wei
- Zhang Xiaolei
- Zhang Xiaoyan
- Zhang Xin
- Zhang Xinxin
- Zhang Xu Dong
- Zhang Yang
- Zhang Yanjin
- Zhang Yi
- Zhang Ying-Dong
- Zhang Yingmei
- Zhang Yuan-Yuan
- Zhang Yuchen
- Zhang Zhe
- Zhang Zhengguang
- Zhang Zhibing
- Zhang Zhihai
- Zhang Zhiyong
- Zhang Zili
- Zhao Haobin
- Zhao Lei
- Zhao Shuang
- Zhao Tongbiao
- Zhao Xiao-Fan
- Zhao Ying
- Zhao Yongchao
- Zhao Yongliang
- Zhao Yuting
- Zheng Guoping
- Zheng Kai
- Zheng Ling
- Zheng Shizhong
- Zheng Xi-Long
- Zheng Yi
- Zheng Zu-Guo
- Zhivotovsky Boris
- Zhong Qing
- Zhou Ao
- Zhou Ben
- Zhou Cefan
- Zhou Gang
- Zhou Hao
- Zhou Hong
- Zhou Hongbo
- Zhou Jie
- Zhou Jing
- Zhou Jing
- Zhou Jiyong
- Zhou Kailiang
- Zhou Rongjia
- Zhou Xu-Jie
- Zhou Yanshuang
- Zhou Yinghong
- Zhou Yubin
- Zhou Zheng-Yu
- Zhou Zhou
- Zhu Binglin
- Zhu Changlian
- Zhu Guo-Qing
- Zhu Haining
- Zhu Hongxin
- Zhu Hua
- Zhu WeiGuo
- Zhu Yanping
- Zhu Yushan
- Zhuang Haixia
- Zhuang Xiaohong
- Zientara-Rytter Katarzyna
- Zimmermann Christine M
- Ziviani Elena
- Zoladek Teresa
- Zong Wei-Xing
- Zorov Dmitry B
- Zorzano Antonio
- Zou Weiping
- Zou Zhen
- Zou Zhengzhi
- Zuryn Steven
- Zwerschke Werner
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field