Training Specialists in the Field of Innovative Financial Technologies in Russia

Formation of educational programs for new types of activity is a complex task that should be solved on the basis of interaction between educational institutions and the professional community, assessment of the current market demand for specialists with certain competencies. But the task becomes much more complicated if the need for specialists is growing rapidly, and the community of professionals is just being formed and cannot have the proper impact on the educational services market. In this case, the educational infrastructure, under certain conditions, can become a controlling component of market development, but it can also become a factor in false goal-setting and inhibition of development.The popularity of financial technologies among the population and applicants prompts higher educational institutions to form educational programs, which are often criticized, and graduates do not always gain employment in accordance with their diploma qualifications. There is a contradiction between the expectations of the labor market, which have not yet been formalized, and the supply from Russian educational institutions.Purpose. The article aims to formulate proposals for the standardization of requirements for specialists in innovative financial technologies (FinTech) based on the consolidation and analysis of the opinions of companies professionally involved in FinTech. Research methods. The authors applied generalization and empirical research methods such as selective market research, statistical observation. Results. The results of an empirical study on the existing educational programs in the sphere of financial technology (Fintech) are presented. Scientific novelty. It is shown that in the conditions of an underdeveloped market and the initial stage of a professional community development, educational infrastructure can become a tool for market development based on a common understanding and standardization of educational competencies and programming of its further development. Practical significance. Taking into account the results obtained, conclusions were formulated that make it possible to substantiate the need to introduce an independent assessment of the formed qualifications into the educational process

Review of the some specific features of the detecting of heavy recoils

In this paper, we present the results of the first beam tests of the detection system at the focal plane of the Dubna Gas-Filled Recoil Separator-2 (DGFRS-2), which receives beams from the DC-280 FLNR cyclotron. The high beam intensity of $^{48}$Ca$^{+10}$ heavy ions from the cyclotron enables us to obtain a number of superheavy recoils sufficient to compare both the measured and calculated spectra of superheavy recoils implanted into a silicon detector. A real-time algorithm to search for an Evaporation Residue (ER) -- $\alpha$ correlated sequences is described in brief. It should be noted that the DGFRS-2 spectrometer operates in conjunction with the 48x128 strip DSSD (Double-sided Silicon Strip Detector; 48x226 mm2) detector and a low-pressure pentane-filled gaseous detector (1.2 Torr; 80x230 mm$^2$). A block-diagram of the spectrometer and the event format are also presented. Special attention is paid to the response of a low-pressure pentane-filled DeltaE multiwire proportional chamber for recoils of Fl, synthesized in the $^{242}$Pu+$^{48}$Ca $\to$ $^{287}$Fl +3n complete fusion nuclear reaction. Some actual parameters of the detection system have also been extracted from $^{\rm nat}$Yb + $^{48}$Ca, $^{232}$Th + $^{48}$Ca, $^{243}$Am + $^{48}$Ca, $^{238}$U + $^{48}$Ca reactions. The effect of neighbor strip charge sharing for the ohmic side of the DSSD detector is also under consideration.Comment: 18 page

Predictive and prognostic significance of mRNA expression and DNA copies aberrations of ERCC1, RRM1, TOP1, TOP2A, TUBB3, TYMS, and GSTP1 genes in patients with breast cancer

Increasingly, many researchers are focusing on the sensitivity in breast tumors (BC) to certain chemotherapy drugs and have personalized their research based on the assessment of this sensitivity. One such personalized approach is to assess the chemotherapy’s gene expression, as well as aberrations in the number of DNA copies—deletions and amplifications with the ability to have a significant effect on the gene’s activity. Thus, the aim of this work was to study the predictive and prognostic significance of the expression and chromosomal aberrations of eight chemosensitivity genes in breast cancer patients. Material and methods. The study involved 97 patients with luminal B breast cancer IIB–IIIB stages. DNA and RNA were isolated from samples of tumor tissue before and after treatment. Microarray analysis was performed for all samples on high-density microarrays (DNA chips) of Affymetrix (USA) CytoScanTM HD Array and Clariom™ S Assay, human. Detection of expression level of seven chemosensitivity genes—RRM1, ERCC1, TOP1, TOP2a, TUBB3, TYMS, and GSTP1—was performed using PCR real-time (RT-qPCR). Results. The expression of the RRM1 (AC scheme), TOP2a, TYMS, and TUBB3 genes in patients with an objective response to treatment (complete and partial regression) is higher than in patients with stabilization and progression (p < 0.05). According to our results, the presence of a high level of GSTP1 in a tumor biopsy is associated with the low efficiency of the NAC CP scheme (p = 0.05). The presence of RRM1 deletion is associated with complete and partial regression, as for the TOP1 and TUBB3 genes (p < 0.05). Higher rates of metastatic survival are associated with a high level of expression and amplification of the GSTP1 gene (log-rank test p = 0.02 and p = 0.05). Conclusion. Thus, a complex assessment of the chemotherapy’s gene expression is important not only for understanding the heterogeneity and molecular biology of breast cancer but also to obtain a more accurate disease prognosis

X-ray emission from the Sombrero galaxy: discrete sources

We present a study of discrete X-ray sources in and around the bulge-dominated, massive Sa galaxy, Sombrero (M104), based on new and archival Chandra observations with a total exposure of ~200 ks. With a detection limit of L_X = 1E37 erg/s and a field of view covering a galactocentric radius of ~30 kpc (11.5 arcminute), 383 sources are detected. Cross-correlation with Spitler et al.'s catalogue of Sombrero globular clusters (GCs) identified from HST/ACS observations reveals 41 X-rays sources in GCs, presumably low-mass X-ray binaries (LMXBs). We quantify the differential luminosity functions (LFs) for both the detected GC and field LMXBs, whose power-low indices (~1.1 for the GC-LF and ~1.6 for field-LF) are consistent with previous studies for elliptical galaxies. With precise sky positions of the GCs without a detected X-ray source, we further quantify, through a fluctuation analysis, the GC LF at fainter luminosities down to 1E35 erg/s. The derived index rules out a faint-end slope flatter than 1.1 at a 2 sigma significance, contrary to recent findings in several elliptical galaxies and the bulge of M31. On the other hand, the 2-6 keV unresolved emission places a tight constraint on the field LF, implying a flattened index of ~1.0 below 1E37 erg/s. We also detect 101 sources in the halo of Sombrero. The presence of these sources cannot be interpreted as galactic LMXBs whose spatial distribution empirically follows the starlight. Their number is also higher than the expected number of cosmic AGNs (52+/-11 [1 sigma]) whose surface density is constrained by deep X-ray surveys. We suggest that either the cosmic X-ray background is unusually high in the direction of Sombrero, or a distinct population of X-ray sources is present in the halo of Sombrero.Comment: 11 figures, 5 tables, ApJ in pres

Observation of enhanced nuclear stability near the 162 neutron shell

In bombardments of {sup 248}Cm with {sup 22}Ne the authors discovered two new isotopes, {sup 265}106 and {sup 266}106, by establishing genetic links between {alpha} decays of the 106 nuclides and SF or {alpha} decays of the daughter (grand-daughter) nuclides. For {sup 266}106 they measured E{sub {alpha}}=8.62{+-}0.06 MeV followed by the SF decay of {sup 262}104 for which they measured a half-life value of 1.2{sup +1.0}{sub {minus}0.5} s. For {sup 265}106 they measured E{sub {alpha}}=8.82{+-}0.06 MeV. They estimated {alpha} half-lives of 10-30 s for {sup 266}106 and 2-30 s for {sup 265}106 with SF branches of {approximately}50% or less. The decay properties of {sup 266}106 indicate a large enhancement in the SF stability of this N=160 nuclide and confirm the existence of the predicted neutron-deformed shell N=162

Attempt to produce element 120 in the 244 Pu + 58 Fe reaction

An experiment aimed at the synthesis of isotopes of element 120 has been performed using the 244 Pu( 58 Fe,xn) 302−x 120 reaction. No decay chains consistent with fusion-evaporation reaction products were observed during an irradiation with a beam dose of 7.1 × 10 18 330-MeV 58 Fe projectiles. The sensitivity of the experiment corresponds to a cross section of 0.4 pb for the detection of one decay