Export intensity and financial performance of Portuguese Small and Medium Enterprises (SME)

Mestrado em FinançasO objectivo desta investigação é estudar a intensidade exportadora das Pequenas e Médias Empresas (PME) em Portugal. A relação entre a intensidade exportadora e o desempenho financeiro é analisado em detalhe. A análise empírica é baseada na amostra das PME da indústria transformadora obtida através dos dados contabilísticos do Sistema de Contas Integradas das Empresas (SCIE). São analisados dois modelos de intensidade exportadora das PME, linear e probit, tendo em conta dois tipos de variáveis dependentes: (i) a percentagem das vendas no mercado externo (considerando-se; e (ii) uma variável binária que mede a predominância exportadora (valor 1 para percentagens de vendas externas superiores a 50%). Como variáveis explicativas foram testadas variáveis relacionadas com as características das empresas (por exemplo, dimensão, nível tecnológico, custos salariais) e com o desempenho financeiro (por exemplo, endividamento, autonomia financeira). Os resultados são mistos dependendo do modelo e da amostra estudada, no entanto, no geral, o retorno sobre os activos, a produtividade, o resultado líquido e o rácio da dívida têm uma relação positiva com a intensidade exportadora. A dimensão e o nível tecnológico também têm um impacto positivo. O salário médio por trabalhador tem um efeito negativo na intensidade exportadora, sugerindo uma competitividade internacional baseada nos custos.The purpose of this investigation is to explain the export intensity of Small and Medium Enterprises (SME) in Portugal. The relation between export intensity and financial performance is analyzed in detail. The empirical analysis is based on a sample of SME firms from the manufacturing sector obtained from the firm-level accounting data Sistema de Contas Integradas das Empresas (SCIE). Two models of export intensity of SMEs are analyzed, linear and probit, considering two kinds of dependent variables: (i) the percentage of foreign sales (considering; and (ii) a binary variable that measures the predominance (value 1 for percentages of foreign sales higher than 50%). As explanatory variables are tested variables related to company characteristics (e.g. size, technological level, wage costs) and to financial performance (e.g. debt, financial autonomy). Results are mixed depending on the model or sample studied, however, in general, return on assets, productivity, net result and debt-to-equity ratio have a positive relationship with the export intensity. Size and technological level also impacted positively. Average wage has a negative effect on export intensity, suggesting an international competitiveness based on costs

Rhinitis associated with asthma is distinct from rhinitis alone: TARIA‐MeDALL hypothesis

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis.info:eu-repo/semantics/publishedVersio

Characterisation of microbial attack on archaeological bone

As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved

Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study

Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting