High-z radio starbursts host obscured X-ray AGN

We use Virtual Observatory methods to investigate the association between radio and X-ray emission at high redshifts. Fifty-five of the 92 HDF(N) sources resolved by combining MERLIN+VLA data were detected by Chandra, of which 18 are hard enough and bright enough to be obscured AGN. The high-z population of microJy radio sources is dominated by starbursts an order of magnitude more active and more extended than any found at z<1 and at least a quarter of these simultaneously host highly X-ray-luminous obscured AGN.Comment: 4 pages, 2 figures, To appear in the proceedings of 'At the Edge of the Universe' (9-13 October 2006, Sintra, Portugal

The radio spectra of the compact sources in Arp 220: A mixed population of supernovae and supernova remnants

We report the first detection at multiple radio wavelengths (13, 6 and 3.6 cm) of the compact sources within both nuclei of the Ultra Luminous Infra-Red Galaxy Arp 220. We present the radio spectra of the 18 detected sources. In just over half of the sources we find that these spectra and other properties are consistent with the standard model of powerful Type IIn supernovae interacting with their pre-explosion stellar wind. The rate of appearance of new radio sources identified with these supernova events suggests that an unusually large fraction of core collapse supernovae in Arp 220 are highly luminous; possibly implying a radically different stellar initial mass function or stellar evolution compared to galactic disks. Another possible explanation invokes very short (~3 x 10^5 year) intense (~10^3 M_Sol year^-1) star formation episodes with a duty cycle of ~10%. A second group of our detected sources, consisting of the brightest and longest monitored sources at 18 cm do not easily fit the radio supernova model. These sources show a range of spectral indexes from -0.2 to -1.9. We propose that these are young supernova remnants which have just begun interacting with a surrounding ISM with a density between 10^4 and 10^5 cm^-3. One of these sources is probably resolved at 3.6 cm wavelength with a diameter 0.9 pc. In the western nucleus we estimate that the ionized component of the ISM gives rise to foreground free-free absorption with opacity at 18 cm of <0.6 along the majority of lines of sight. Other sources may be affected by absorption with opacity in the range 1 to 2. These values are consistent with previous models as fitted to the radio recombination lines and the continuum spectrum.Comment: 44 pages, 9 figures, 2 tables. Accepted for publication in Ap

Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms.

Interstitial pulmonary fibrosis induced by intratracheal instillation of bleomycin (BL) involves an excess production of reactive oxygen species, unavailability of adequate levels of NAD and ATP to repair the injured pulmonary epithelium, and an overexuberant lung collagen reactivity followed by deposition of highly cross-linked mature collagen fibrils resistant to enzymatic degradation. In the present study, we have demonstrated that dietary supplementation with taurine and niacin offered almost complete protection against the lung fibrosis in a multidose BL hamster model. The mechanisms for the protective effect of taurine and niacin are multifaceted. These include the ability of taurine to scavenge HOCl and stabilize the biomembrane; niacin's ability to replenish the BL-induced depletion of NAD and ATP; and the combined effect of taurine and niacin to suppress all aspects of BL-induced increases in the lung collagen reactivity, a hallmark of interstitial pulmonary fibrosis. It was concluded from the data presented at this Conference that the combined treatment with taurine and niacin, which offers a multipronged approach, will have great therapeutic potential in the intervention of the development of chemically induced interstitial lung fibrosis in animals and humans

Modelling Collision Products of Triple-Star Mergers

In dense stellar clusters, binary-single and binary-binary encounters can ultimately lead to collisions involving two or more stars. A comprehensive survey of multi-star collisions would need to explore an enormous amount of parameter space, but here we focus on a number of representative cases involving low-mass main-sequence stars. Using both Smoothed Particle Hydrodynamics (SPH) calculations and a much faster fluid sorting software package (MMAS), we study scenarios in which a newly formed product from an initial collision collides with a third parent star. By varying the order in which the parent stars collide, as well as the orbital parameters of the collision trajectories, we investigate how factors such as shock heating affect the chemical composition and structure profiles of the collision product. Our simulations and models indicate that the distribution of most chemical elements within the final product is not significantly affected by the order in which the stars collide, the direction of approach of the third parent star, or the periastron separations of the collisions. We find that the sizes of the products, and hence their collisional cross sections for subsequent encounters, are sensitive to the order and geometry of the collisions. For the cases that we consider, the radius of the product formed in the first (single-single star) collision ranges anywhere from roughly 2 to 30 times the sum of the radii of its parent stars. The final product formed in our triple-star collisions can easily be as large or larger than a typical red giant. We therefore expect the collisional cross section of a newly formed product to be greatly enhanced over that of a thermally relaxed star of the same mass.Comment: 20 pages, submitted to MNRA

Using VO tools to investigate distant radio starbursts hosting obscured AGN in the HDF(N) region

A 10-arcmin field around the HDF(N) contains 92 radio sources >40 uJy, resolved by MERLIN+VLA at 0".2-2".0 resolution. 55 have Chandra X-ray counterparts including 18 with a hard X-ray photon index and high luminosity characteristic of a type-II (obscured) AGN. >70% of the radio sources have been classified as starbursts or AGN using radio morphologies, spectral indices and comparisons with optical appearance and MIR emission. Starbursts outnumber radio AGN 3:1. This study extends the VO methods previously used to identify X-ray-selected obscured type-II AGN to investigate whether very luminous radio and X-ray emission originates from different phenomena in the same galaxy. The high-redshift starbursts have typical sizes of 5--10 kpc and star formation rates of ~1000 Msun/yr. There is no correlation between radio and X-ray luminosities nor spectral indices at z>~1.3. ~70% of both the radio-selected AGN and the starburst samples were detected by Chandra. The X-ray luminosity indicates the presence of an AGN in at least half of the 45 cross-matched radio starbursts, of which 11 are type-II AGN including 7 at z>1.5. This distribution overlaps closely with the X-ray detected radio sources which were also detected by SCUBA. Stacked 1.4-GHz emission at the positions of radio-faint X-ray sources is correlated with X-ray hardness. Most extended radio starbursts at z>1.3 host X-ray selected obscured AGN. Radio emission from most of these ultra-luminous objects is dominated by star formation but it contributes less than 1/3 of their X-ray luminosity. Our results support the inferences from SCUBA and IR data, that at z>1.5, star formation is an order of magnitude more extended and more copious, it is closely linked to AGN activity and it is triggered differently, compared with star formation at lower redshifts.Comment: 24 pages, 12 figures, uses graphicx, rotating, natbib, supertabular packages and aa.cls. Accepted for publication in A&

Mutualism and Adaptive Divergence: Co-Invasion of a Heterogeneous Grassland by an Exotic Legume-Rhizobium Symbiosis

Species interactions play a critical role in biological invasions. For example, exotic plant and microbe mutualists can facilitate each other's spread as they co-invade novel ranges. Environmental context may influence the effect of mutualisms on invasions in heterogeneous environments, however these effects are poorly understood. We examined the mutualism between the legume, Medicago polymorpha, and the rhizobium, Ensifer medicae, which have both invaded California grasslands. Many of these invaded grasslands are composed of a patchwork of harsh serpentine and relatively benign non-serpentine soils. We grew legume genotypes collected from serpentine or non-serpentine soil in both types of soil in combination with rhizobium genotypes from serpentine or non-serpentine soils and in the absence of rhizobia. Legumes invested more strongly in the mutualism in the home soil type and trends in fitness suggested that this ecotypic divergence was adaptive. Serpentine legumes had greater allocation to symbiotic root nodules in serpentine soil than did non-serpentine legumes and non-serpentine legumes had greater allocation to nodules in non-serpentine soil than did serpentine legumes. Therefore, this invasive legume has undergone the rapid evolution of divergence for soil-specific investment in the mutualism. Contrary to theoretical expectations, the mutualism was less beneficial for legumes grown on the stressful serpentine soil than on the non-serpentine soil, possibly due to the inhibitory effects of serpentine on the benefits derived from the interaction. The soil-specific ability to allocate to a robust microbial mutualism may be a critical, and previously overlooked, adaptation for plants adapting to heterogeneous environments during invasion

Scaling up the effects of inbreeding depression from individuals to metapopulations

Abstract Inbreeding is common in nature, and many laboratory studies have documented that inbreeding depression can reduce the fitness of individuals. Demonstrating the consequences of inbreeding depression on the growth and persistence of populations is more challenging because populations are often regulated by density- or frequency-dependent selection and influenced by demographic and environmental stochasticity. A few empirical studies have shown that inbreeding depression can increase extinction risk of local populations. The importance of inbreeding depression at the metapopulation level has been conjectured based on population-level studies but has not been evaluated. We quantified the impact of inbreeding depression affecting the fitness of individuals on metapopulation persistence in heterogeneous habitat networks of different sizes and habitat configuration in a context of natural butterfly metapopulations. We developed a spatial individual-based simulation model of metapopulations with explicit genetics. We used Approximate Bayesian Computation to fit the model to extensive demographic, genetic, and life-history data available for the well-studied Glanville fritillary butterfly (Melitaea cinxia) metapopulations in the Åland islands in SW Finland. We compared 18 semi-independent habitat networks differing in size and fragmentation. The results show that inbreeding is more frequent in small habitat networks, and consequently, inbreeding depression elevates extinction risks in small metapopulations. Metapopulation persistence and neutral genetic diversity maintained in the metapopulations increase with the total habitat amount in and mean patch size of habitat networks. Dispersal and mating behavior interact with landscape structure to determine how likely it is to encounter kin while looking for mates. Inbreeding depression can decrease the viability of small metapopulations even when they are strongly influenced by stochastic extinction-colonization dynamics and density-dependent selection. The findings from this study support that genetic factors, in addition to demographic factors, can contribute to extinctions of small local populations and also of metapopulations. This article is protected by copyright. All rights reserved.Peer reviewe

A mathematical model for breath gas analysis of volatile organic compounds with special emphasis on acetone

Recommended standardized procedures for determining exhaled lower respiratory nitric oxide and nasal nitric oxide have been developed by task forces of the European Respiratory Society and the American Thoracic Society. These recommendations have paved the way for the measurement of nitric oxide to become a diagnostic tool for specific clinical applications. It would be desirable to develop similar guidelines for the sampling of other trace gases in exhaled breath, especially volatile organic compounds (VOCs) which reflect ongoing metabolism. The concentrations of water-soluble, blood-borne substances in exhaled breath are influenced by: (i) breathing patterns affecting gas exchange in the conducting airways; (ii) the concentrations in the tracheo-bronchial lining fluid; (iii) the alveolar and systemic concentrations of the compound. The classical Farhi equation takes only the alveolar concentrations into account. Real-time measurements of acetone in end-tidal breath under an ergometer challenge show characteristics which cannot be explained within the Farhi setting. Here we develop a compartment model that reliably captures these profiles and is capable of relating breath to the systemic concentrations of acetone. By comparison with experimental data it is inferred that the major part of variability in breath acetone concentrations (e.g., in response to moderate exercise or altered breathing patterns) can be attributed to airway gas exchange, with minimal changes of the underlying blood and tissue concentrations. Moreover, it is deduced that measured end-tidal breath concentrations of acetone determined during resting conditions and free breathing will be rather poor indicators for endogenous levels. Particularly, the current formulation includes the classical Farhi and the Scheid series inhomogeneity model as special limiting cases.Comment: 38 page