6 research outputs found

    Community Engagement newsletter, Faculty of Veterinary Science, Winter, 2012

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    Mangaung community receives support from Onderstepoort / Willem Engelbrecht, Helzna Krikke, Ingrid Metz, Janine Lombard, Marelize Greyling and Willem Janson -- Fighting animal abuse one school at a time / Ruche Harmse, Taryn Light, Ansu Visser, Este van Coetzen, Megan Naude, Nadia Strydom and Tess Tjasink -- Veterinary education and “Vets for the kids” / Patrick Ntsibande, Nyeleti Manganyi, Noluthando Ndashe, Thapelo Makae, Khulekani Lukhele and Sabelo Magagula -- soVETo k9 Mobile clinic outreach / Daleen Bester, Gideon Stemmet, Ian Gibson, Kobus Rabe, Louw Grobler and Rhynard de RidderNews articles with colour photos about the various community engagement projects of the Faculty of Veterinary Science, University of Pretoria.ab201

    The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

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    INTRODUCTION Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic. RATIONALE We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs). RESULTS Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants. CONCLUSION Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century

    Staff perceptions on talent management and retention: A case of a labour organisation in Gauteng

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    As high turnover is costly and disruptive, all organisations aim to retain talented employees. Talented employees give organisations a competitive advantage in the complex business environment of today. The aim of this article is to report on the employees’ perceptions of talent management retention at a labour organisation in Gauteng. The population comprised 317 permanent staff members, and a convenience sample of 162 was used. A principal factor analysis was employed to determine the main factors, namely, dedication to staff and dedication of staff. Descriptive statistics were used to determine the perceptions of staff members on these two factors. In conclusion, recommendations are offered to labour relations practitioners on how human resource practices can contribute to the fair treatment and retention of talented employees in an organisation

    Effect of visual feedback on classroom noise levels

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    This study explored the effect of visual feedback on classroom noise levels, using a SoundEar II device that monitors noise levels in real time with feedback on intensity levels using a lighting system. During phase one, noise levels from three classrooms in the same school were measured over 36 h of classroom activities. For phase two, six teachers from two schools completed a questionnaire describing their experiences using the device. Visual feedback resulted in a 1.4-dBA reduction in the average noise levels. Classroom noise levels were above 70 dBA for 33% of the time in the baseline period compared to 24% in the intervention period with visual feedback provided on noise levels. Teacher perceptions indicated that visual feedback was beneficial to classroom noise levels and positively influenced the behaviour of learners. Visual feedback reduced overall classroom noise and can provide a cost-effective, noninvasive tool to create a more enabling classroom environment

    Nanoengineered Drug Delivery Systems for Enhancing Antibiotic Therapy

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