Association of index of welfare and metabolism with the genetic merit of holstein and simmental cows after the peak of lactation

The study investigated the relationship of markers of welfare and metabolism in milk, urine and blood with the genetic merit of Holstein and Simmental cows after the peak of lactation. Cows were selected from 3 Simmental (IS) and 2 Holstein (IH) commercial dairy farms. Within each farm, cows were ranked according to the estimated breeding value for milk protein yield (EBVp) from minus to positive and selected every 5 EBVps from minus to positive values (about 20% lactating cows for each farm). Milk was sampled and analysed for protein, fat, lactose, cortisol contents and somatic cell count (SCC). Blood and urines were analysed for biomarkers of metabolism and welfare. Significantly lower body condition score (BCS) was observed for IH in comparison to IS. Plasma creatinine was higher in IS, whilst Zn, total antioxidant status and glutathione peroxidase was higher in IH. The creatinine N to N ratio in urine was significantly higher for IS, while the purine derivatives (PD) N to creatinine N ratio was higher for IH. The EBVp was negatively related to BCS and glucose for IS and to plasma b-hydroxybutyrate in both breeds. EBVp was negatively Related to urinary PD N to total N ratios for IS and to PD N to creatinine N ratio for IH. These preliminary results would indicate that the selection of cows for milk protein yield had minor effect on plasma and milk biomarkers of welfare. Instead, biomarkers of metabolism were more affected by breed and genetic merit

How does the pitch and pattern of a signal affect auditory arousal thresholds?

How arousal thresholds vary with different sounds is a critical issue for emergency awakenings, especially as sleepers are dying in fires despite having a working smoke alarm. Previous research shows that the current high pitched (3000+ Hz) smoke alarm signal is significantly less effective than an alternative signal, the 520 Hz square wave, in all populations tested. However, as the number of sounds tested has been small further research is needed. Here we measured auditory arousal thresholds (AATs) across signals with a range of characteristics to determine the most effective waking signal. Thirty nine young adults participated over three nights. In Part A, nine signals were presented in stage 4 sleep with ascending decibel levels. Signals were short beeps in the low to mid frequency range with different spectral complexities: square waves, pure tones, whoops and white noise. Part B manipulated temporal patterns, inserting silences of 0, 10 and 21 seconds after each 12 seconds of beeps. It was found that the low frequency (400 and 520 Hz) square waves yielded significantly lower AATs than the alternatives. A trend was found across the three temporal manipulations, with a 10 second intervening silence showing some advantage. These findings support earlier research indicating that the best sound for awakening from deep sleep is a low frequency square wave. It is argued that the signal with the lowest response threshold when awake may be the same as the most arousing signal when asleep, especially where the sleeper processes the signal as meaningful

Social interactions and the demand for sport: an economic analysis

‘The definitive version is available at www3.interscience.wiley.com '. Copyright Blackwell Publishing DOI: 10.1111/j.1465-7287.2007.00071.xThis paper explores the decision to participate in sports activities in the UK and the subsequent frequency of participation. The paper draws links between economic and other theories of social interaction to motivate the discussion and links these theories to assessing policy initiatives in the UK. Cluster analysis is combined with a Heckman analysis to examine the empirical evidence provided by the General Household Survey in 2002. The results suggest that social and personal capital are of paramount importance in determining sports participation and consequently it is these features that policy should focus upon.Peer reviewe

The initial measurement structure of the Home Drinking Assessment Scale (HDAS)

Aims: To evaluate the initial psychometric properties of a novel Home Drinking Assessment Scale (HDAS). Participants: Five-hundred and twenty-five (58% female) participants recruited from the internet address book of an English University. This also included a sub-sample (6%) recruited from Twitter and Facebook contacts. Design and methods: Internet-based survey analysed using a two-stage factor analysis protocol and internal consistency(IC) assessment. Findings: A power calculation was made on the basis of pilot data and this established that 317 interviewees were required to test the reliability of the HDAS. The items comprising the HDAS were found to offer the best fit to data when they comprised two-subscales: (1) emotional reasons for home drinking (5-items) and (2) practical reasons for home drinking (3-items). Subscale 1 was also found to have acceptable IC whereas subscale 2 exhibited sub-optimal IC characteristics. Conclusions: This initial study indicates that the HDAS has promise as a measure of the individuals' rationale for home drinking. Subscale 1, may usefully be used in future research whereas the IC characteristics of subscale 2 suggests that further development is required, including the evaluation of additional items

Length of Stay after Vaginal Birth: Sociodemographic and Readiness-for-Discharge Factors

Background: The impact of reductions in postpartum length of stay have been widely reported, but factors influencing length of hospital stay after vaginal birth have received less attention. The study purpose was to compare the sociodemographic characteristics and readiness for discharge of new mothers and their newborns at 3 discharge time intervals, and to determine which variables were associated with postpartum length of stay. Methods: The study sample comprised 1,192 mothers who were discharged within 2 postpartum days after uncomplicated vaginal birth at a tertiary perinatal center in the midwestern United States. The sample was divided into 3 postpartum length-of-stay groups: group 1 (18–30 hr), group 2 (31–42 hr), and group 3 (43–54 hr). Sociodemographic and readiness-for-discharge data were collected by self-report and from a computerized hospital information system. Measures of readiness for discharge included perceived readiness (single item and Readiness for Discharge After Birth Scale), documented maternal and neonatal clinical problems, and feeding method. Results: Compared with other groups, the longest length-of-stay group was older; of higher socioeconomic status and education; and with more primiparous, breastfeeding, white, married mothers who were living with the baby’s father, had adequate home help, and had a private payor source. This group also reported greater readiness for discharge, but their newborns had more documented clinical problems during the postbirth hospitalization. In logistic regression modeling, earlier discharge was associated with young age, multiparity, public payor source, low socioeconomic status, lack of readiness for discharge, bottle-feeding, and absence of a neonatal clinical problem. Conclusions: Sociodemographic chracteristics and readiness for discharge (clinical and perceived) were associated with length of postpartum hospital stay. Length of stay is an outcome of a complex interface between patient, provider, and payor influences on discharge timing that requires additional study. Including perceived readiness for discharge in clinical discharge criteria will add an important dimension to assessment of readiness for discharge after birth

Childhood conscientiousness predicts the social gradient of smoking in adulthood: a life course analysis.

The social gradient in smoking is well known, with higher rates among those in less advantaged socioeconomic position. Some recent research has reported that personality characteristics partly explain this gradient. However, the majority of existing work is limited by cross-sectional designs unsuitable to determine whether differences in conscientiousness are a predictor or a product of social inequalities. Adopting a life course perspective, we investigated in the current paper the influence of conscientiousness in early and mid-life on the social gradient in smoking and the role of potential confounding factors in a large longitudinal cohort study

Incidence and correlates of delirium in a West African mental health clinic

Objective: <br/> <br/> To determine the incidence of delirium in those patients presenting to a psychiatric clinic in Nigeria and to examine if any demographic or clinical variables were correlated with this diagnosis. <br/> <br/> Method <br/> <br/> A prospective survey design; 264 consecutive new referrals to a psychiatric clinic in Nigeria were assessed for the presence of delirium using a standardised diagnostic scale. Data was analysed for normality and appropriate statistical test employed to examine the relationships between the presence of delirium and demographic and clinical variables. <br/> <br/> Results <br/> <br/> Of individuals presenting to the mental health clinics, 18.2% had delirium. No demographic variable was significant regarding the presence or absence of delirium. With regard to clinical variables duration of current symptoms, referral source and the presence of comorbid physical illness were significantly associated with the presence of delirium. Most delirium was due to infections. Nearly all patients with delirium were prescribed psychotropic medication (95.2%), and most attributed their symptoms to a spiritual cause.Conclusion(s) Delirium presents more commonly to psychiatry services in the less developed world compared to the West. Development efforts should focus on recognition and management of delirium to improve outcomes and maximise resource