Observation of an Excited Bc+ State

Using pp collision data corresponding to an integrated luminosity of 8.5 fb-1 recorded by the LHCb experiment at center-of-mass energies of s=7, 8, and 13 TeV, the observation of an excited Bc+ state in the Bc+π+π- invariant-mass spectrum is reported. The observed peak has a mass of 6841.2±0.6(stat)±0.1(syst)±0.8(Bc+) MeV/c2, where the last uncertainty is due to the limited knowledge of the Bc+ mass. It is consistent with expectations of the Bc∗(2S31)+ state reconstructed without the low-energy photon from the Bc∗(1S31)+→Bc+γ decay following Bc∗(2S31)+→Bc∗(1S31)+π+π-. A second state is seen with a global (local) statistical significance of 2.2σ (3.2σ) and a mass of 6872.1±1.3(stat)±0.1(syst)±0.8(Bc+) MeV/c2, and is consistent with the Bc(2S10)+ state. These mass measurements are the most precise to date

Measurement of the inelastic pp cross-section at a centre-of-mass energy of 13TeV

The cross-section for inelastic proton-proton collisions at a centre-of-mass energy of 13TeV is measured with the LHCb detector. The fiducial cross-section for inelastic interactions producing at least one prompt long-lived charged particle with momentum p > 2 GeV/c in the pseudorapidity range 2 < η < 5 is determined to be ϭ acc = 62:2 ± 0:2 ± 2:5mb. The first uncertainty is the intrinsic systematic uncertainty of the measurement, the second is due to the uncertainty on the integrated luminosity. The statistical uncertainty is negligible. Extrapolation to full phase space yields the total inelastic proton-proton cross-section ϭ inel = 75:4 ± 3:0 ± 4:5mb, where the first uncertainty is experimental and the second due to the extrapolation. An updated value of the inelastic cross-section at a centre-of-mass energy of 7TeV is also reported

Assessment of plasma chitotriosidase activity, CCL18/PARC concentration and NP-C suspicion index in the diagnosis of Niemann-Pick disease type C: A prospective observational study

Background: Niemann-Pick disease type C (NP-C) is a rare, autosomal recessive neurodegenerative disease caused by mutations in either the NPC1 or NPC2 genes. The diagnosis of NP-C remains challenging due to the non-specific, heterogeneous nature of signs/symptoms. This study assessed the utility of plasma chitotriosidase (ChT) and Chemokine (C-C motif) ligand 18 (CCL18)/pulmonary and activation-regulated chemokine (PARC) in conjunction with the NP-C suspicion index (NP-C SI) for guiding confirmatory laboratory testing in patients with suspected NP-C. Methods: In a prospective observational cohort study, incorporating a retrospective determination of NP-C SI scores, two different diagnostic approaches were applied in two separate groups of unrelated patients from 51 Spanish medical centers (n = 118 in both groups). From Jan 2010 to Apr 2012 (Period 1), patients with =2 clinical signs/symptoms of NP-C were considered ''suspected NP-C'' cases, and NPC1/NPC2 sequencing, plasma chitotriosidase (ChT), CCL18/PARC and sphingomyelinase levels were assessed. Based on findings in Period 1, plasma ChT and CCL18/PARC, and NP-C SI prediction scores were determined in a second group of patients between May 2012 and Apr 2014 (Period 2), and NPC1 and NPC2 were sequenced only in those with elevated ChT and/or elevated CCL18/PARC and/or NP-C SI =70. Filipin staining and 7-ketocholesterol (7-KC) measurements were performed in all patients with NP-C gene mutations, where possible. Results: In total across Periods 1 and 2, 10/236 (4%) patients had a confirmed diagnosis o NP-C based on gene sequencing (5/118 4.2%] in each Period): all of these patients had two causal NPC1 mutations. Single mutant NPC1 alleles were detected in 8/236 (3%) patients, overall. Positive filipin staining results comprised three classical and five variant biochemical phenotypes. No NPC2 mutations were detected. All patients with NPC1 mutations had high ChT activity, high CCL18/PARC concentrations and/or NP-C SI scores =70. Plasma 7-KC was higher than control cut-off values in all patients with two NPC1 mutations, and in the majority of patients with single mutations. Family studies identified three further NP-C patients. Conclusion: This approach may be very useful for laboratories that do not have mass spectrometry facilities and therefore, they cannot use other NP-C biomarkers for diagnosis

Updated Determination of D⁰–D¯⁰Mixing and CP Violation Parameters with D⁰→K⁺π⁻ Decays

We report measurements of charm-mixing parameters based on the decay-time-dependent ratio of D⁰→K⁺π⁻ to D⁰→K⁻π⁺ rates. The analysis uses a data sample of proton-proton collisions corresponding to an integrated luminosity of 5.0  fb⁻¹ recorded by the LHCb experiment from 2011 through 2016. Assuming charge-parity (CP) symmetry, the mixing parameters are determined to be x′²=(3.9±2.7)×10⁻⁵, y′=(5.28±0.52)×10⁻³, and R[subscript D]=(3.454±0.031)×10⁻³. Without this assumption, the measurement is performed separately for D⁰ and D[over ¯]⁰ mesons, yielding a direct CP-violating asymmetry A[subscript D]=(-0.1±9.1)×10⁻³, and magnitude of the ratio of mixing parameters 1.00<|q/p|<1.35 at the 68.3% confidence level. All results include statistical and systematic uncertainties and improve significantly upon previous single-measurement determinations. No evidence for CP violation in charm mixing is observed

Measurement of CP observables in B± → D(⁎)K± and B± → D(⁎)π± decays

Measurements of CP observables in B ± →D (⁎) K ± and B ± →D (⁎) π ± decays are presented, where D (⁎) indicates a neutral D or D ⁎ meson that is an admixture of D (⁎)0 and D¯ (⁎)0 states. Decays of the D ⁎ meson to the Dπ 0 and Dγ final states are partially reconstructed without inclusion of the neutral pion or photon, resulting in distinctive shapes in the B candidate invariant mass distribution. Decays of the D meson are fully reconstructed in the K ± π ∓ , K + K − and π + π − final states. The analysis uses a sample of charged B mesons produced in pp collisions collected by the LHCb experiment, corresponding to an integrated luminosity of 2.0, 1.0 and 2.0 fb −1 taken at centre-of-mass energies of s=7, 8 and 13 TeV, respectively. The study of B ± →D ⁎ K ± and B ± →D ⁎ π ± decays using a partial reconstruction method is the first of its kind, while the measurement of B ± →DK ± and B ± →Dπ ± decays is an update of previous LHCb measurements. The B ± →DK ± results are the most precise to date

Measurement of branching fractions of charmless four-body Λ_b ⁰ and Ξ_b ⁰ decays

A search for charmless four-body decays of Λb 0 and Ξb 0 baryons with a proton and three charged mesons (either kaons or pions) in the final state is performed. The data sample used was recorded in 2011 and 2012 with the LHCb experiment and corresponds to an integrated luminosity of 3 fb−1. Six decay modes are observed, among which Λb 0 → pK−π+π−,Λb 0 → pK−K+K−,Ξb 0 → pK−π+π− and Ξb 0 → pK−π+K− are established for the first time. Their branching fractions (including the ratio of hadronisation fractions in the case of the Ξb 0 baryon) are determined relative to the Λb 0 → Λc +π− decay.[Figure not available: see fulltext.].</p

Measurement of forward top pair production in the dilepton channel in <i>pp</i> collisions at √s=13 TeV

Forward top quark pair production is studied in $pp$ collisions in the $\mu eb$ final state using a data sample corresponding to an integrated luminosity of 1.93 fb$^{-1}$ collected with the LHCb experiment at a centre-of-mass energy of 13 TeV. The cross-section is measured in a fiducial region where both leptons have a transverse momentum greater than 20 GeV and a pseudorapidity between 2.0 and 4.5. The quadrature sum of the azimuthal separation and the difference in pseudorapidities, denoted $\Delta R$, between the two leptons must be larger than 0.1. The $b$-jet axis is required to be separated from both leptons by a $\Delta R$ of 0.5, and to have a transverse momentum in excess of 20 GeV and a pseudorapidity between 2.2 and 4.2. The cross-section is measured to be $$\sigma_{t\bar{t}}= 126\pm19\,(\mathrm{stat})\pm16\,(\mathrm{syst})\pm5\,(\mathrm{lumi})\,\,\mathrm{ fb}$$ where the first uncertainty is statistical, the second is systematic, and the third is due to the luminosity determination. The measurement is compatible with the Standard Model prediction.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2017-050.htm

Search for weakly decaying b -flavored pentaquarks

Investigations of the existence of pentaquark states containing a single b (anti)quark decaying weakly into four specific final states J/ψK+π-p, J/ψK-π-p, J/ψK-π+p, and J/ψφ(1020)p are reported. The data sample corresponds to an integrated luminosity of 3.0 fb-1 in 7 and 8 TeV pp collisions acquired with the LHCb detector. Signals are not observed and upper limits are set on the product of the production cross section times branching fraction with respect to that of the Λb0

Updated determination of D 0 - D 0 mixing and C P violation parameters with D 0 → K + π -

We report measurements of charm-mixing parameters based on the decay-time-dependent ratio of D0→K+π- to D0→K-π+ rates. The analysis uses a data sample of proton-proton collisions corresponding to an integrated luminosity of 5.0 fb-1 recorded by the LHCb experiment from 2011 through 2016. Assuming charge-parity (CP) symmetry, the mixing parameters are determined to be x′2=(3.9±2.7)×10-5, y′=(5.28±0.52)×10-3, and RD=(3.454±0.031)×10-3. Without this assumption, the measurement is performed separately for D0 and D0 mesons, yielding a direct CP-violating asymmetry AD=(-0.1±9.1)×10-3, and magnitude of the ratio of mixing parameters 1.00<|q/p|<1.35 at the 68.3% confidence level. All results include statistical and systematic uncertainties and improve significantly upon previous single-measurement determinations. No evidence for CP violation in charm mixing is observed

Measurement of the CP asymmetry in B- -&gt; (Ds-D0) and B- -&gt; (D-D0) decays

The CP asymmetry in B- -&gt; (Ds-D0) and B- -&gt; (D-D0) decays is measured using LHCb data corresponding to an integrated luminosity of 3.0 fb(-1), collected in pp collisions at centre-of-mass energies of 7 and 8TeV. The results are A(CP) (B- -&gt; (Ds-D0)) = (-0.4 +/- 0.5 +/- 0.5)% and A(CP) (B- -&gt; (D-D0)) = (2.3 +/- 2.7 +/- 0.4)%, where the first uncertainties are statistical and the second systematic. This is the first measurement of A(CP) (B- -&gt; (Ds-D0)) and the most precise determination of A(CP) (B- -&gt; (D-D0)). Neither result shows evidence of CP violation