2,666 research outputs found
Proton pump inhibitors and the risk of pneumonia: A comparison of cohort and self-controlled case series designs
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2013
- Field of study
Background: To compare the results of a new-user cohort study design and the self-controlled case series (SCCS) design using the risk of hospitalisation for pneumonia in those dispensed proton pump inhibitors compared to those unexposed as a case study. Methods: The Australian Government Department of Veteransâ Affairs administrative claims database was used. Exposure to proton pump inhibitors and hospitalisations for pneumonia were identified over a 4 year study period 01 Jul 2007 -30 Jun 2011. The same inclusion and exclusion criteria were applied to both studies, however, the SCCS study included subjects with a least one hospitalisation for pneumonia. Results: There were 105,467 subjects included in the cohort study and 6775 in the SCCS. Both studies showed an increased risk of hospitalisations for pneumonia in the three defined risk periods following initiation of proton pump inhibitors compared to baseline. With the highest risk in the first 1 to 7 days (Cohort RR, 3.24; 95% CI (2.50, 4.19): SCCS: RR, 3.07; 95% CI (2.69, 3.50)). Conclusions: This study has shown that the self-controlled case series method produces similar risk estimates to a new-users cohort study design when applied to the association of proton pump inhibitors and pneumonia. Exposure to a proton pump inhibitor increases the likelihood of being admitted to hospital for pneumonia, with the risk highest in the first week of treatment.Emmae N Ramsay, Nicole L Pratt, Philip Ryan and Elizabeth E Roughea
Seroprevalence of brucellosis in horses in kars and ardahan provinces of turkey where ruminant brucellosis is endemic and prevalent
- Publication venue
- 'Kafkas University'
- Publication date
- 01/05/2013
- Field of study
GLR in Colorectal Cancers: An Easily Accessible Prognostic Marker
- Publication venue
- 'Dove Medical Press Ltd.'
- Publication date
- 01/05/2024
- Field of study
İsa Caner Aydin,1 Ismail Ege Subasi,2 Ahmet Orhan Sunar,1 Serkan Ademoglu,1 Selcuk Gulmez,1 Mursit Dincer,1 Mustafa Duman,1 Erdal Polat1 1University of Health Sciences, Kartal Kosuyolu Training and Research Hospital, Gastroenterologic Surgery Department, Istanbul, Turkey; 2University of Health Sciences, Van City Hospital Gastroenterologic Surgery Department, Van, TurkeyCorrespondence: İsa Caner Aydin, University of Health Sciences, Kartal Kosuyolu Training and Research Hospital, Gastroenterologic Surgery Department, Email [email protected] and Objectives: Colorectal cancer remains a significant health concern, necessitating reliable prognostic indicators for effective management. This study explores the preoperative prognostic significance of the Glucose/Lymphocyte Ratio (GLR) in colorectal cancers.Methods: The study retrospectively analyzed records of patients who underwent surgery for elective colorectal cancers between January 1, 2013, and December 31, 2021, at the Koşuyolu Training and Research Hospital Gastroenterologic Surgery Department. Demographic, clinicopathological, and follow-up data were comprehensively assessed. A cutoff was established from GLR ratios and patients were divided into two groups for prognosis analysis.Results: The study enrolled 222 eligible patients, examining variables such as age, sex, ASA score, neoadjuvant treatment, lymphovascular and perineural invasion, tumor grade, TNM stage, and GLR. The groups consisted of 128 patients with low GLR and 94 patients with high GLR. Statistical analyses revealed relations between GLR levels (p ⤠0.001) and various prognostic factors such as age (p = 0.034), Perineural Invasion (PNI) (p = 0.002), tumor grade (p = 0.017), TNM stage (p = 0.003), and surgery time (p = 0.029), individuals with GLR ⼠3.04 were observed to show higher mortality rates (p = 0.001). Above GLR cutoff point of 3.04 patients showed better overall survival rates. All survival related parameters were related with prognosis in univariant Cox regression tests. In multivariant cox regression tests GLR ⼠3.04 significantly increased mortality by 2.9 times. (p = 0.003).Conclusion: This study demonstrates that GLR, calculated from preoperative glucose and lymphocyte values serves as an independent prognostic factor in colorectal cancers. The findings suggest potential applications for GLR in survival analyses, with significant associations identified in age, PNI, tumor grade, TNM stage, and surgery time. Further investigations are warranted in homogeneous patient populations.Keywords: colorectal cancer, prognostic factor, survival, Glucose-to-lymphocyte Ratio, cancer-specific surviva
Measurement of Charged Pion Production Yields off the NuMI Target
- Author
- Akgun U.
- Asner D. M.
- Aydin G.
- Baker W.
- Barnes Jr., P. D.
- Bergfeld T.
- Beverly L.
- Bhatnagar V.
- Choudhary B.
- Dukes E. C.
- Duru F.
- Feldman G. J.
- Godley A.
- Graf N.
- Gronberg J.
- Gulmez E.
- Gunaydin Y. O.
- Gustafson H. R.
- Hanlet P.
- Hartouni E. P.
- Heffner M.
- Kamaev O.
- Kaplan D. M.
- Klay J.
- Kumar A.
- Lange D. J.
- Lebedev A.
- Ling J.
- Longo M. J.
- Lu L. C.
- Mahajan S.
- Materniak C.
- Messier M. D.
- Meyer H.
- Miller D. E.
- Mishra S. R.
- Nelson K.
- Nigmanov T.
- Norman A.
- Onel Y.
- Paley J. M.
- Penzo A.
- Peterson R. J.
- Raja R.
- Rajaram D.
- Ratnikov D.
- Rosenfeld C.
- Rubin H.
- Seun S.
- Singh A.
- Solomey N.
- Soltz R. A.
- Torun Y.
- Wilson K.
- Wright D. M.
- Wu Q. K.
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 23/04/2014
- Field of study
The fixed-target MIPP experiment, Fermilab E907, was designed to measure the
production of hadrons from the collisions of hadrons of momenta ranging from 5
to 120 GeV/c on a variety of nuclei. These data will generally improve the
simulation of particle detectors and predictions of particle beam fluxes at
accelerators. The spectrometer momentum resolution is between 3 and 4%, and
particle identification is performed for particles ranging between 0.3 and 80
GeV/c using dE/dx, time-of-flight and Cherenkov radiation measurements. MIPP
collected 1.42Ă106 events of 120 GeV Main Injector protons striking a
target used in the NuMI facility at Fermilab. The data have been analyzed and
we present here charged pion yields per proton-on-target determined in bins of
longitudinal and transverse momentum between 0.5 and 80 GeV/c, with combined
statistical and systematic relative uncertainties between 5 and 10%.Comment: 15 pages, 13 figure
First observation of a narrow charm-strange meson DsJ(2632) -> Ds eta and D0 K+
- Author
- A. A. Vorobyov
- A. G. Atamantchouk
- A. G. Dolgolenko
- A. G. Krivshich
- A. I. Kulyavtsev
- A. I. Sitnikov
- A. N. Vasiliev
- A. P. Kozhevnikov
- A. P. Nilov
- A. S. Ayan
- A. V. Evdokimov
- A. V. Nemitkin
- A. Kushnirenko
- A. Lamberto
- A. Morelos
- A. Ocherashvili
- A. Penzo
- Amf Endler
- B. V. Razmyslovich
- C. O. Escobar
- C. Newsom
- D. V. Vavilov
- D. Mao
- D. Skow
- E. M. Leikin
- E. Gulmez
- E. Mccliment
- E. Ozel
- E. Ramberg
- E. Vazquez Jauregui
- F. G. Garcia
- G. B. Dzyubenko
- G. F. Rappazzo
- G. V. Davidenko
- G. Alkhazov
- Gaspero Mario
- H. Kangling
- H. Kruger
- I. S. Filimonov
- I. Eschrich
- I. Giller
- I. Konorov
- I. Larin
- I. Torres
- J. Amaro Reyes
- J. Engelfried
- J. Kilmer
- J. Lach
- J. Russ
- J. Simon
- J. You
- K. D. Nelson
- K. Vorwalter
- L. G. Landsberg
- L. J. Dauwe
- L. M. Kochenda
- L. N. Uvarov
- L. Emediato
- L. Stutte
- L. Yunshan
- M. A. Kubantsev
- M. A. Moinester
- M. Y. Balatz
- M. Chensheng
- M. Iori
- M. Kaya
- M. Luksys
- M. Mattson
- M. Procario
- M. Srivastava
- M. Svoiski
- M. Zhenlin
- N. F. Bondar
- N. K. Terentyev
- N. P. Kuropatkin
- P. S. Cooper
- P. V. Neoustroev
- P. Gouffon
- P. Mathew
- P. Pogodin
- P. Schiavon
- R. Edelstein
- R. Zukanovich Funchal
- S. B. Nurushev
- S. V. Petrenko
- S. Y. Jun
- S. Kwan
- S. Ozkorucuklu
- T. Lungov
- Thomas Gp
- U. Akgun
- U. Dersch
- V. A. Victorov
- V. E. Vishnyakov
- V. F. Kurshetsov
- V. I. Rud
- V. J. Smith
- V. L. Golovtsov
- V. P. Kubarovsky
- V. P. Maleev
- V. S. Verebryusov
- V. T. Kim
- V. V. Molchanov
- V. Matveev
- V. Steiner
- V. Stepanov
- Y. Onel
- Z. Shuchen
- Z. Wenheng
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2004
- Field of study
We report the first observation of a charm-strange meson DsJ(2632) at a mass
of 2632.6+/-1.6 MeV/c^2 in data from SELEX, the charm hadro-production
experiment E781 at Fermilab. This state is seen in two decay modes, Ds eta and
D0 K+. In the Ds eta decay mode we observe an excess of 49.3 events with a
significance of 7.2sigma at a mass of 2635.9+/-2.9 MeV/c^2. There is a
corresponding peak of 14 events with a significance of 5.3sigma at 2631.5+/-1.9
MeV/c^2 in the decay mode D0 K+. The decay width of this state is <17 MeV/c^2
at 90% confidence level. The relative branching ratio Gamma(D0K+)/Gamma(Dseta)
is 0.16+/-0.06. The mechanism which keeps this state narrow is unclear. Its
decay pattern is also unusual, being dominated by the Ds eta decay mode.Comment: 5 pages, 3 included eps figures. v2 as accepted for publication by
PR
Measurement of the Z/gamma* + b-jet cross section in pp collisions at 7 TeV
- Author
- Abbaneo D.
- Abbiendi G.
- Abbrescia M.
- Abdullin S.
- Acosta D.
- Acosta J. G.
- Acosta M. Vazquez
- Adair A.
- Adam N.
- Adam W.
- Adams M. R.
- Adams T.
- Adiguzel A.
- Adler V.
- Adzic P.
- Afanasiev S.
- Agostino L.
- Agram J-L
- Aguilar-Benitez M.
- Aguilo E.
- Ahmad M.
- Ahmad W. Haj
- Ahuja S.
- Akchurin N.
- Akgun B.
- Akgun U.
- Akin I. V.
- Alagoz E.
- Albajar C.
- Albayrak E. A.
- Albergo S.
- Albrow M.
- Alcaraz Maestre J.
- Alda Junior W. L.
- Alexander J.
- Aliev T.
- Almeida N.
- Alver B.
- Alverson G.
- Alves G. A.
- Amapane N.
- Amsler C.
- Anagnostou G.
- Anastassov A.
- Anderson J.
- Anderson M.
- Andrea J.
- Andreev V.
- Andreev V.
- Andreev Yu.
- Andrews W.
- Anghel I. M.
- Anjos T. S.
- Antonelli L.
- Antunes J. Rodrigues
- Antunovic Z.
- Apanasevich L.
- Apollinari G.
- Appelt E.
- Apresyan A.
- Aranyi A.
- Arce P.
- Arcidiacono R.
- Arenton M. W.
- Arfaei H.
- Argiro S.
- Arisaka K.
- Arneodo M.
- Arora S.
- Asawatangtrakuldee C.
- Asghar M. I.
- Askew A.
- Assran Y.
- Ata M.
- Atac M.
- Atramentov O.
- Attikis A.
- Auffray E.
- Autermann C.
- Auzinger G.
- Avdeeva E.
- Avery P.
- Avetisyan A.
- Azarkin M.
- Azhgirey I.
- Aziz T.
- Azzi P.
- Azzolini V.
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- Baarmand M. M.
- Babb J.
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- Bakhshiansohi H.
- Bakirci M. N.
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- Balazs M.
- Ball A. H.
- Ball G.
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- Banerjee S.
- Banerjee S.
- Bansal S.
- Banzuzi K.
- Barbagli G.
- Barberis E.
- Barbone L.
- Bardak C.
- Barfuss A. F.
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- Barker A.
- Barnes V. E.
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- Belforte S.
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- Belotelov I.
- Belyaev A.
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- Benaglia A.
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- Benelli G.
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- Beranek S.
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2012
- Field of study
The production of b jets in association with a Z/gamma* boson is studied
using proton-proton collisions delivered by the LHC at a centre-of-mass energy
of 7 TeV and recorded by the CMS detector. The inclusive cross section for
Z/gamma* + b-jet production is measured in a sample corresponding to an
integrated luminosity of 2.2 inverse femtobarns. The Z/gamma* + b-jet cross
section with Z/gamma* to ll (where ll = ee or mu mu) for events with the
invariant mass 60 < M(ll) < 120 GeV, at least one b jet at the hadron level
with pT > 25 GeV and abs(eta) < 2.1, and a separation between the leptons and
the jets of Delta R > 0.5 is found to be 5.84 +/- 0.08 (stat.) +/- 0.72 (syst.)
+(0.25)/-(0.55) (theory) pb. The kinematic properties of the events are also
studied and found to be in agreement with the predictions made by the MadGraph
event generator with the parton shower and the hadronisation performed by
PYTHIA.Comment: Submitted to the Journal of High Energy Physic
Azimuthal anisotropy of charged particles at high transverse momenta in PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
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- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
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- Zatserklyaniy A
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- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
The azimuthal anisotropy of charged particles in PbPb collisions at
nucleon-nucleon center-of-mass energy of 2.76 TeV is measured with the CMS
detector at the LHC over an extended transverse momentum (pt) range up to
approximately 60 GeV. The data cover both the low-pt region associated with
hydrodynamic flow phenomena and the high-pt region where the anisotropies may
reflect the path-length dependence of parton energy loss in the created medium.
The anisotropy parameter (v2) of the particles is extracted by correlating
charged tracks with respect to the event-plane reconstructed by using the
energy deposited in forward-angle calorimeters. For the six bins of collision
centrality studied, spanning the range of 0-60% most-central events, the
observed v2 values are found to first increase with pt, reaching a maximum
around pt = 3 GeV, and then to gradually decrease to almost zero, with the
decline persisting up to at least pt = 40 GeV over the full centrality range
measured.Comment: Replaced with published version. Added journal reference and DO
Compressed representation of a partially defined integer function over multiple arguments
- Author
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- Abbiendi G
- Abbrescia M
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- Cripps N
- Cuevas J
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- Cumalat JP
- Cussans D
- Custodio A
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
- D'Alessandro R
- D'Alfonso M
- d'Enterria D
- D'Hondt J
- Da Costa EM
- Dabrowski A
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- Publication venue
- Publication date
- 01/01/2013
- Field of study
In OLAP (OnLine Analitical Processing) data are analysed in an n-dimensional cube. The cube may be represented as a partially defined function over n arguments. Considering that often the function is not defined everywhere, we ask: is there a known way of representing the function or the points in which it is defined, in a more compact manner than the trivial one
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
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- Yilmaz Y
- Yohay R
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
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- Ziebarth EB
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
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- Acosta MV
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- Wakefield S
- Wallny R
- Walsh R
- Walsh S
- Waltenberger W
- Walzel G
- Wan Z
- Wang D
- Wang J
- Wang J
- Wang M
- Wang S
- Wang X
- Wang Z
- Wardle N
- Wardrope D
- Wasserbaech S
- Wayne M
- Weber H
- Weber HA
- Weber M
- Weber M
- Wehrli L
- Weiler T
- Weinberg M
- Wendland L
- Weng J
- Weng Y
- Wenger EA
- Werner JS
- West C
- Wetzel J
- Whitbeck A
- Whitmore J
- Whyntie T
- Wickens J
- Wickramage N
- Widl E
- Wigmans R
- Wilken R
- Wilkinson R
- Williams G
- Williams T
- Willmott C
- Wimpenny S
- Winn D
- Winstrom L
- Wissing C
- Wittich P
- Wittmer B
- Woehri HK
- Wolf M
- Wolf R
- Womersley WJ
- Won S
- Wood D
- Wood J
- Wood JS
- Worm SD
- Wright D
- Wrochna G
- Wu W
- Wuerthwein F
- Wulz C-E
- Wyslouch B
- Xiao H
- Xie S
- Xu M
- Yagil A
- Yalvac M
- Yang F
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
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