24 research outputs found

    On the second order properties of the multidimensional periodogram for regularly spaced data

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    Recently there is growing interest in improving the level of knowledge of spatial and spatio-temporal processes using spectral techniques. The properties of the estimator of the spectral density, the periodogram, have been broadly studied under different asymptotic assumptions that imply a valuable loss of information about the behavior of the underlying process that is often observed on a grid of small size and with sparse data. In this scheme, neither increasing domain nor shrinking asymptotics applies. The goal of this paper is to study the properties of the multidimensional periodogram, under both cases of tapering and no tapering, and the assumption of finite dimensionality of the regular lattice where the process is observed. We present some theoretical results regarding the second order properties of the multidimensional periodogram. Furthermore, we show that, independent of the tapering procedure, periodogram values present a dependence structure which is not stationary and which particularly depends on weights which are proportional to the Bartlett kernel or the chosen taperThis work was supported by the Spanish Ministry of Science and Education project MTM2005-0020 and grants MTM2004-06231 and BES2003-0581, and by Xunta de Galicia projects PGIDIT06PXIB207009PR and PGIDIT03PXIC20702PNS

    Estadística no paramétrica: pasado, presente y futuro

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    La estadística no paramétrica engloba una serie de técnicas de inferencia cuya característica principal es la ausencia de un modelo paramétrico de distribución subyacente. Sin pretender revisar todos y cada uno de los conceptos e ideas que conforman este planteamiento, es nuestro objetivo que el lector se familiarice con términos como técnicas de suavizado, Bootstrap, verosimilitud empírica o datos funcionales, su porqué, su utilidad, su relevancia en la estadística actual y la posible proyección hacia el futuroS

    A test for directional-linear independence, with applications to wildfire orientation and size

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    Original PaperA nonparametric test for assessing the independence between a directional random variable (circular or spherical, as particular cases) and a linear one is proposed in this paper. The statistic is based on the squared distance between nonparametric kernel density estimates and its calibration is done by a permutation approach. The size and power characteristics of various variants of the test are investigated and compared with those for classical correlation-based tests of independence in an extensive simulation study. Finally, the best-performing variant of the new test is applied in the analysis of the relation between the orientation and size of Portuguese wildfire

    Short-course thrombolysis as the first line of therapy for cardiac valve thrombosis

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    AbstractObjective: To retrospectively evaluate the clinical and echocardiographic criteria of thrombolytic therapy for mechanical heart valve thrombosis. Methods: Nineteen consecutive patients with 22 instances of prosthetic heart valve thrombosis (14 mitral, 2 aortic, 3 tricuspid, and 3 pulmonary) were treated with short-course thrombolytic therapy as first option of treatment in absence of contraindications. The thrombolytic therapy protocol consisted of streptokinase (1,500,000 IU in 90 minutes) (n = 18) in one (n = 7) or two (n = 11) cycles or recombinant tissue-type plasminogen activator (100 mg in 90 minutes) (n = 4). Results: Overall success was seen in 82%, immediate complete success in 59%, and partial success in 23%. Six patients without total response to thrombolytic therapy underwent surgery, and pannus was observed in 83%. Six patients showed complications: allergy, stroke, transient ischemic attack, coronary embolism, minor bleeding, and one death. At diagnosis, 10 patients evidenced atrial thrombus by transesophageal echocardiography, 3 of whom experienced peripheral embolism during thrombolysis. Four episodes of rethrombosis were observed (16%). The survivorship was 84% with a mean follow-up of 42.6 months. Conclusions: A short-course of thrombolytic therapy may be considered first-line therapy for prosthetic heart valve thrombosis. The risk of peripheral embolism may be evaluated for the presence of atrial thrombus by transesophageal echocardiography at diagnosis. (J Thorac Cardiobasc Surg 1998;115:780-4

    Staging, neurocognition and social functioning in bipolar disorder.

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    Introduction: Bipolar disorder (BD) is associated with significant neurocognitive and functional impairment, which may progress across stages. The 'latent stage' of BD remains understudied. This cross-sectional study assessed staging, neurocognition and social functioning among BD patients and their healthy siblings. Methods: Four groups were included: euthymic type I BD patients in the early (n = 25) and late (n = 23) stages, their healthy siblings (latent stage; n = 23) and healthy controls (n = 21). All 92 subjects underwent a comprehensive neuropsychological battery of processing speed, verbal learning/memory, visual memory, working memory, verbal fluency, executive cognition, and motor speed. Social functioning was assessed using the FAST scale. Results: Siblings' social functioning was identical to that of controls, and significantly better than both early- (p < 0.005) and late- (p < 0.001) stage patients. Although all patients were strictly euthymic, those at late stages had a significantly worse social functioning than early-stage patients (p < 0.001). Compared to controls, increasingly greater neurocognitive dysfunction was observed across stages of BD (F = 1.59; p = 0.005). Healthy siblings' performance lied between those of controls and patients, with deficits in tasks of processing speed, executive attention, verbal memory/learning, and visual memory. Both early- and late-stage patients had a more severe and widespread dysfunction than siblings, with no significant differences between them. Conclusions: Genetic vulnerability to BD-I seems to be associated with neurocognitive impairments, whereas social dysfunction would be the result of the clinical phenotype. Staging models of BD should take into account these divergent findings in the latent stage
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