3D Modelling of Jerusalem’s Maghrebi Quarter

Although Jerusalem is one of the most photographed places in the world, few works have focused on the existence of its former 800-year-old Maghrebi Quarter, located in the shadow of the Western Wall. Founded in 1193 by Saladin’s son, al-Afdal ‘Ali to house Muslim pilgrims from North Africa (today Morocco, Algeria, Tunisia, and Libya), the Quarter was razed by Israeli bulldozers on the night of 10–11 June 1967’. Its 1,000 or so inhabitants were forced to flee within hours. Silenced by the occupation of East Jerusalem as part of the Six-Day War, the existence of the Maghrebi Quarter faded behind the walls of history. This research paper describes how 55 years after its razing, the selection of a corpus of archives, combined with 3D technology and Interprofessional collaborations between historians and 3D designers enable making a forgotten history accessible again. Beyond a discussion on methods and technical process, this research paper aims to highlight the potential applications of the data set and the 3D model not only for scholarly research but also for pedagogical purposes, for instance

Ewing Sarcoma of the Bone in Children under 6 Years of Age

BACKGROUND: Ewing Sarcoma Family Tumours (ESFT) are rare in early childhood. The aim of this study was to report the clinical characteristics and outcome of children under 6 years of age affected by ESFT of the bone in Italy. METHODS: The records of all the children diagnosed with osseous ESFT in centres members of the Associazione Italiana di Ematologia ed Oncologia Pediatrica (AIEOP) from 1990 to 2008 were reviewed. The Kaplan-Meier method was used for estimating overall and progression-free survival (OS, PFS) curves; multivariate analyses were performed using Cox proportional hazards regression model. RESULTS: This study includes 62 patients. An axial primary localization was present in 66% of patients, with the primary site in the chest wall in 34%. Fourteen (23%) patients presented metastatic disease. The 5-year OS and PFS were 73% (95% confidence interval, CI, 58-83%) and 72% (95% CI 57-83%) for patients with localized disease and 38% (95% CI 17-60%) and 21% (95% CI 5-45%) for patients with metastatic disease. Metastatic spread, skull/pelvis/spine primary localization, progression during treatment and no surgery predicted worse survival (P<0.01), while patients treated in the last decade had better survival (P = 0.002). In fact, the 5-year OS and PFS for patients diagnosed in the period 2000-2008 were 89% (95% CI 71-96%) and 86% (95% CI 66-94%), respectively. CONCLUSION: The axial localization is the most common site of ESFT in pre-scholar children. Patients treated in the most recent period have an excellent outcome

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Esopo: Sensors and social pollution measurements

In the following we present the idea of a smart sensor distributed platform where users collect pollution measurements by simply placing a small smart device out of their office or home window, a device that interacts with their smartphones. They provide time-geolocalized information that, trough an app, will be made available to the community that will have the chance to control the pollution level and eventually share it on the most popular social networks along with the related user's opinions and feedbacks. The big data coming from sensors and social networks will be analysed, in combination with local setting area data, in order to have a thorough view of the place the people live in and enhance our environmental conscience. The design of such a project, named Esopo, implies and requires technologies capable of providing data privacy, as it deals also with storing sensitive data, and efficiency, being the corresponding output prone to becoming unusable if not produced in real-time

Dive in the Past: A Serious Game to Promote the Underwater Cultural Heritage of the Mediterranean Sea

In the last decades, the popularity of video games has been increasing thanks to their unique ability to engage their audience and create empathy. Among them, serious games have additional purposes besides entertainment, such as learning and behaviour change. Serious games, in fact, have been successfully applied to different fields, including education, health, tourism, and cultural heritage. In this context, the paper describes a novel serious game developed for increasing awareness and promoting the Underwater Cultural Heritage (UCH). In particular, the paper focuses on the Dive in the Past Serious Game which allows users to simulate a virtual dive into the Mediterranean Sea to explore accurate and life-sized 3D reconstructions of underwater archaeological sites. The purpose of the game is twofold: to engage diver and non-diver tourists into a virtual interactive exploration of underwater sites through digital storytelling and challenges; to increase awareness and knowledge on Mediterranean UCH. This work has been carried out in the context of the MeDryDive project, an EU co-funded under the COSME Programme, which aims to create personalized dry dive experiences for the promotion of Mediterranean UCH sites as distinctive tourism destinations

Dive in the Past: A Serious Game to Promote the Underwater Cultural Heritage of the Mediterranean Sea

In the last decades, the popularity of video games has been increasing thanks to their unique ability to engage their audience and create empathy. Among them, serious games have additional purposes besides entertainment, such as learning and behaviour change. Serious games, in fact, have been successfully applied to different fields, including education, health, tourism, and cultural heritage. In this context, the paper describes a novel serious game developed for increasing awareness and promoting the Underwater Cultural Heritage (UCH). In particular, the paper focuses on the Dive in the Past Serious Game which allows users to simulate a virtual dive into the Mediterranean Sea to explore accurate and life-sized 3D reconstructions of underwater archaeological sites. The purpose of the game is twofold: to engage diver and non-diver tourists into a virtual interactive exploration of underwater sites through digital storytelling and challenges; to increase awareness and knowledge on Mediterranean UCH. This work has been carried out in the context of the MeDryDive project, an EU co-funded under the COSME Programme, which aims to create personalized dry dive experiences for the promotion of Mediterranean UCH sites as distinctive tourism destinations

Hybrid and lightweight detection of third party tracking: Design, implementation, and evaluation

A common practice for websites is to rely on services provided by third party sites to track users and provide personalized experiences. Unfortunately, this practice has strong implications for both users and performance. From one hand, the privacy of individuals is at a risk given the use of valuable information used for the reconstruction of personal profiles. From the other hand, many existing countermeasures to protect privacy, having been implemented into Web browsers, exhibit performance issues, mainly due to the use of huge (and difficult to maintain up to date) lists of resources that have to be filtered out, given their privacy intrusiveness. To overcome these limitations, we propose the use of a hybrid mechanism exploiting blacklisting and machine learning for the automatic identification of privacy intrusive services requested while browsing Web pages. The idea is to use the blacklisting technique (widely used by the majority of privacy tools), in combination with a machine learning model which distinguishes between malicious and functional resources, and hence updates the blacklist, accordingly. We found out that machine learning models are able to classify JavaScript programs and HTTP requests with accuracy up to 91% and 97%, respectively. We provided a prototype implementation of this hybrid mechanism, named GuardOne, and we performed an exhaustive evaluation study to assess its effectiveness and performance. Results showed that GuardOne is able to filter out malicious resources from users' requests without performance degradation when compared with traditional systems that leverage on the use of static lists for filtering. Moreover, results about effectiveness show that our mechanism, even with some small improvements, is able to efficiently filter out malicious requests and reduce in a substantial way personal information leakage