17 research outputs found
Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy
- Author
- A Alborghetti
- A Burt
- A Crown
- A Gluckman Beedle
- A Kulis
- A Martin
- A Molina-Carballo
- A Moreau
- A Moreau
- A Moreau
- A Moreau
- A Nordwall
- A Pelijeff
- A Vidil
- A Weltman
- AE Geissele
- AG King
- AG Veldhuizen
- AH Schultz
- AK Roseweir
- AL Mark
- AL Nachemson
- Alan Moulton
- AM Cypess
- AM Haqq
- AP Signore
- AS Kauffman
- B Azeddine
- B Azeddine
- B Cannon
- B Capaldo
- B Kasibhatla
- B Krishnan
- B Sevastik
- BT Bruce
- C Barrios Pitarque
- C Bjørbaek
- C Boulay
- C Boulay
- C Civardi
- C Couturier
- C Couturier
- C Denoel
- C Lafosse
- C Proto
- C Siu King Cheung
- C Syme
- CF Semenkovich
- CJ Goldberg
- CJ Goldberg
- CJ Goldberg
- CJ Goldberg
- CJ Goldberg
- CJ Goldberg
- CJ Goldberg
- CJ Goldberg
- CJ Willer
- CL Reed
- CL White
- CM Steppan
- CO Lovejoy
- CO Lovejoy
- CQ Zhao
- CSK Cheung
- CT Montague
- CWG Man
- D Brockmeyer
- D Leboeuf
- D Mihaila
- DD Matson
- DE Flanagan
- DJ Sucato
- DJ Wever
- DJ Wever
- DL Morris
- DM Bramble
- DM Styne
- E Buommino
- E Kasuya
- E Morgan
- E Resmini
- EA Szalay
- ED Wang
- EJ Calabrese
- EK Dretakis
- EM Scott
- EW Somerville
- F Elefteriou
- F Elefteriou
- F Elefteriou
- F Kristmundsdottir
- F Peelman
- FD Burton
- FJP Ebling
- FM Smith
- FM Smith
- G Day
- G Deane
- G Diene
- G Frühbeck
- G Gat-Yablonski
- G Gat-Yablonski
- G Grugni
- G Hagglund
- G Lynch
- G Maor
- G Sun
- G Taubes
- G Wolf
- GC Man
- GC Robin
- GJ Morton
- GM Edelman
- H Bertram
- H Jiang
- H Mori
- H Neugebauer
- H Neugebauer
- H Normelli
- HJ Li
- HQ Zhang
- HY Yeung
- I Gerendai
- I Prokopenko
- IAF Stokes
- IAF Stokes
- IF MacDonald
- IJ Andersson
- IM Korr
- IM Shapiro
- IS Farooqi
- J Antoniou
- J Bjure
- J Dubousset
- J Fischer
- J Kratzsch
- J Lidström
- J Lin
- J Nedergaard
- J Sarwark
- J Sevastik
- J Sevastik
- J Tam
- J Whelan
- J Wu
- J Yu
- J-WM Kouwenhoven
- JA Roth
- JA Sevastik
- JA Sevastik
- JB Emans
- JC Cheng
- JC Moraes
- JCY Cheng
- JD Schwender
- JF Dymling
- JG Burke
- JK Crean
- JK Elmquist
- JK Howard
- JM Friedman
- JM Gomez
- JM Mac-Thiong
- JO Sanders
- JR Davids
- JW Raczkowski
- JWM Kouwenhoven
- K Bagnall
- K Chen
- K Enslein
- K Letellier
- K Letellier
- K Rahmouni
- K Ward
- KA Virtanen
- KK Ong
- KL Ellacott
- KM Bagnall
- KO Klein
- KS Nicolopoulos
- KX Wang
- L Aiello
- L Aulisa
- L Bandini
- L Fu
- L Iughetti
- L Shi
- LB Skogland
- LD Klaman
- LK Malendowicz
- LP Wu
- M Acampa
- M Beaulieu
- M Elchebly
- M Inoue
- M Karasek
- M Machida
- M Machida
- M Machida
- M Mattson
- M Nissinen
- M Repko
- M Roth
- M Shohat
- M Simoneau
- M Vignolo
- M Wiens
- M Zivicnjak
- MA Serrat
- MF Brown
- MH Mehta
- MH Mehta
- Michael P Grevitt
- MJ McMaster
- MK Badman
- MK Singh
- ML Ahmed
- ML Bouxsein
- ML Correia
- ML Lao
- Ml Power
- MM Abitbol
- MM Macchi
- MP Mattson
- MP Warren
- MP Warren
- MS Patel
- MW Hamrick
- MW Hamrick
- N Eikelis
- N Møller
- N Pannacciulli
- N Timpson
- NH Miller
- NJ Lee
- NK Lee
- O Sporns
- ON Hausmann
- P Ducy
- P Giampietro
- P Iliopoulos
- P Kievit
- P Korovessis
- PA Millner
- PA Parsons
- PB Kaplowitz
- PC Hindmarsh
- PE Clayton
- Peter H Dangerfield
- PF MacNeilage
- PH Dangerfield
- PH Dangerfield
- PH Dangerfield
- PH Dangerfield
- PK Picardi
- PL Docquier
- R de Lind van Wijngaarden
- R Fredriksson
- R Geoffrey Burwell
- R Herman
- R Nakajima
- R Perdriolle
- R Roaf
- R Wynne-Davies
- Ranjit K Aujla
- RC Davey
- RF de Lind van Wijngaarden
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG Burwell
- RG McMurray
- RJ Loos
- RM Castelein
- RM Nesse
- RP Heaney
- RW Porter
- S Akhtar
- S Blakeslee
- S Fujihara
- S Gallagher
- S Jebb
- S Parent
- S Roberts
- S Shadan
- S Takeda
- S Takeda
- S Wang
- S Willner
- S Willner
- SA Kaplan
- SC Cunnane
- SE Myers
- SF Morrison
- SG Hassink
- SJ Allison
- SL Drop
- SL Weinstein
- SM Milenkovic
- SR Farmer
- SR Ladyman
- Susan I Anderson
- T Ahl
- T Hosoi
- T Liu
- T Ljung
- T Nagai
- T Odent
- T Paus
- T Thomas
- Tabitha L Randell
- TB Grivas
- TB Grivas
- TB Grivas
- TB Grivas
- TB Grivas
- TB Grivas
- TB Grivas
- TB Grivas
- TB Grivas
- TB Grivas
- TB Kirkwood
- TG Lowe
- TG Lowe
- TG Lowe
- TJ Bartness
- U Sovio
- UT Iwaniec
- V Lyssenko
- VL Ugrinow
- VWY Hung
- W Chu
- WA Banks
- WCW Chu
- WCW Chu
- WCW Chu
- WD van Marken Lichtenbelt
- WF Enneking
- WG Haynes
- WJ Wang
- WJ Wang
- X Gao
- X Guo
- X Guo
- X Guo
- X Sun
- XS Qiu
- XS Qiu
- XS Qiu
- Y Kishida
- Y Nomura
- Y Oomura
- Y Qiu
- Y-H Tseng
- YB Sverrisdóttir
- YB Sverrisdóttir
- YB Sverrisdóttir
- Publication venue
- BioMed Central
- Publication date
- 01/10/2009
- Field of study
Anthropometric data from three groups of adolescent girls - preoperative adolescent idiopathic scoliosis (AIS), screened for scoliosis and normals were analysed by comparing skeletal data between higher and lower body mass index subsets. Unexpected findings for each of skeletal maturation, asymmetries and overgrowth are not explained by prevailing theories of AIS pathogenesis. A speculative pathogenetic theory for girls is formulated after surveying evidence including: (1) the thoracospinal concept for right thoracic AIS in girls; (2) the new neuroskeletal biology relating the sympathetic nervous system to bone formation/resorption and bone growth; (3) white adipose tissue storing triglycerides and the adiposity hormone leptin which functions as satiety hormone and sentinel of energy balance to the hypothalamus for long-term adiposity; and (4) central leptin resistance in obesity and possibly in healthy females. The new theory states that AIS in girls results from developmental disharmony expressed in spine and trunk between autonomic and somatic nervous systems. The autonomic component of this double neuro-osseous theory for AIS pathogenesis in girls involves selectively increased sensitivity of the hypothalamus to circulating leptin (genetically-determined up-regulation possibly involving inhibitory or sensitizing intracellular molecules, such as SOC3, PTP-1B and SH2B1 respectively), with asymmetry as an adverse response (hormesis); this asymmetry is routed bilaterally via the sympathetic nervous system to the growing axial skeleton where it may initiate the scoliosis deformity (leptin-hypothalamic-sympathetic nervous system concept = LHS concept). In some younger preoperative AIS girls, the hypothalamic up-regulation to circulating leptin also involves the somatotropic (growth hormone/IGF) axis which exaggerates the sympathetically-induced asymmetric skeletal effects and contributes to curve progression, a concept with therapeutic implications. In the somatic nervous system, dysfunction of a postural mechanism involving the CNS body schema fails to control, or may induce, the spinal deformity of AIS in girls (escalator concept). Biomechanical factors affecting ribs and/or vertebrae and spinal cord during growth may localize AIS to the thoracic spine and contribute to sagittal spinal shape alterations. The developmental disharmony in spine and trunk is compounded by any osteopenia, biomechanical spinal growth modulation, disc degeneration and platelet calmodulin dysfunction. Methods for testing the theory are outlined. Implications are discussed for neuroendocrine dysfunctions, osteopontin, sympathoactivation, medical therapy, Rett and Prader-Willi syndromes, infantile idiopathic scoliosis, and human evolution. AIS pathogenesis in girls is predicated on two putative normal mechanisms involved in trunk growth, each acquired in evolution and unique to humans
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf AM
- Abdelrouf DM
- Abdelshafy M
- Abdelshakour M
- Abdrabou AK
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
- Abdulbagi O
- Abdulgawad M
- Abdulhakeem EM
- Abdullah AAN
- Abdullah MA
- Abdullah N
- Abdullah NAN
- Abdullah NAN
- Abdullahi L
- Abdurrazzaaq A
- Abebe NS
- Abebe NS
- Abem OE
- Aber A
- Abington E
- Abiola O
- Aboarab A
- Aboelella M
- Aboelmagd O
- Aboelsoud MR
- Aboraya M
- Aboraya M
- Abouelnasr A
- Aboul-Naga MS
- Abouzahra A
- Abouzaid A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abu Qumbos A
- Abu-toyour M
- Abubakr M
- Abudeeb H
- Abuowda Y
- Abuqwaider E
- Abusalem L
- Abuseif M
- Abushamleh S
- Acharya P
- Ackom E
- Acquah E
- Adam A
- Adam N
- Adams R
- Adamu A
- Adawi I
- Adawi M
- Adebanjo A
- Adebanjo A
- Adebola O
- Adedeji A
- Adekoya A
- Adel A
- Adel A
- Adel BE
- Adel I
- Adella FJ
- Adelshone A
- Ademuyiwa A
- Ademuyiwa A
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
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- Adenekan B
- Adeniran J
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- Adeniyi A
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- Adesanya O
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- Adesina A
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- Adesuyi A
- Adeyeye A
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- Adhitama N
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- Adisa AO
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- Afana S
- Afandy A
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- Agbedinu K
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- Aglan A
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- Aguilar-Jimenez J
- Aguilera M
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- Al Awwad S
- Al Barrawi FE
- Al Bastawis F
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- Al-Azraqi IAA
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- Al-Buhaisi A
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- Al-faqawi M
- Al-farram H
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- Al-Hasani RKMJ
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- Leanne Almanon C
- Lecompte J-F
- Lee C
- Lee EX
- Lee F
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- Lee KC
- Lee KY
- Lee TSB
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- Leone N
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- Leppaniemi A
- Leppaniemi A
- Leroux J
- Leung KW
- Leung MF
- Leusink A
- Lewis J
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- Li KKK
- Li WS
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- Liew I
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- Lilford R
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- Lim G
- Lim H
- Lim J
- Lim PJ
- Lim SJ
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- Lim SY
- Limache S
- Limaye N
- Limoges B
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- lo Conte A
- loaloa MR
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- Ma J
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- Macchitella Y
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- Maceviciute K
- Macfarlane A
- Machaca M
- Machain Vega GM
- Machain Vega GM
- Maciejec L
- Madiba T
- Madkor MH
- Madrid Barrientos LA
- Maffioli A
- Maffioli A
- Magdy A
- Magdy B
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- Magdy H
- Magdy M
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- Magee C
- Maghrabi A
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- Mahmoud B
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- Mamdouh R
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- Manchego Bautista AC
- Manchego Bautista AC
- Manfreda S
- Mangan C
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- Mangiapane M
- Manipal CE
- Maniscalco A
- Mann T
- Mannu GS
- Mano MJB
- Manrique Sila G
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- Mansor EY
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- Marroquin Rodriguez DE
- Marshall DC
- Martian B-V
- Martin A
- Mas R
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- Matos-Puig R
- Mattar O
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- Menegussi J
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- Merlo MS
- Mesbah N
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- Metwally MM
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- Mihaljevic AL
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- Mircea H
- Mirghani D
- Mironescu A
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- Mirza A
- Mirza S
- Mistry A
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- Mitroudi M
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- Moaty M
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- Modolo MM
- Moe TT
- Mogan YP
- Moghazy ME
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- Mohamed A
- Mohamed AM
- Mohamed AR
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed MA
- Mohamed MAEH
- Mohamed MM
- Mohamed O
- Mohamed SR
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
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- Mohammed AR
- Mohammed H
- Mohammed MM
- Mohammed MMH
- Mohammed S
- Mohan H
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- Mok YT
- Mokhtar A
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- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montoya Botero JA
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
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- Mora JJV
- Morales C
- Morandi E
- Moreira G
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- Morsi A
- Morsi M
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- Morton R
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- Mosalum O
- Mostafa HA
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
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- Mshelbwala P
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- Pesenti G
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- Samaraweera DI
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- Snyder E
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- Sobnach S
- Sodde P
- Soeselo DA
- Sokratous A
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- Solar Garcia L
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- Soldevila-Verdeguer C
- Soley R
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- Soltani N
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- Sriram A
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- Stefanopoulos A
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- Summerour V
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- Taddei A
- Tade A
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- Tahboub H
- Taher AA
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- Taieb C
- Taiwo A
- Taiwo O
- Taiwo O
- Talaat M
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- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
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- De Franciscis S
- De Freitas AVC
- De La Medina AR
- de Leó
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- de Lima CVB
- De Luca E
- De Marco P
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- Delforge X
- Delgado Jm
- Delgado Msftl
- Dell A
- Dempster E
- Denewar A
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- Devadasar Gh
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- Di Martino N
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- Diab A
- Diaconescu B
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- Djivoh F
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- El Hamid NA
- El Jamassi A
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- El Mesery S
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- El Sayed IM
- El Shoura Y
- El Slam MA
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- El-Din Ra
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- El-Latif Nka
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- Eldeeb Az
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- Elkhadrawi M
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- Elkorashy Am
- Ellison Q
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- Elsameea Aa
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- Elsherbiny As
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- Elzowawi F
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- Espinoza F
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- Farinella E
- Farmakis K
- Farooq T
- Farouk Sam
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy Am
- Fattah Aa
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
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- Fermani C
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- Grobler Dc
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- Halicioglu I
- Hall E
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- Hamarshi A
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- Haslegrave A
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- Hassaan A
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- Ibraheem Aa
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- Ibrahem Aa
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- Ibrahim A
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- Ibrahim Am
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- Ibrahim I
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- Macdonald E
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- Maceviciute K
- Macfarlane A
- Machaca M
- Maciejec L
- Madiba T
- Madkor Mh
- Maffioli A
- Maffioli A
- Magdy A
- Magdy B
- Magdy E
- Magdy H
- Magdy M
- Magdy S
- Magee C
- Maghrabi A
- Maghrabi Aa
- Magri D
- Mahamood Ab
- Mahanty S
- Maharaj G
- Mahdi A
- Mahdi S
- Mahdi S
- Maher Me
- Mahmoud B
- Mahmoud H
- Mahmoud M
- Mahmoud Ma
- Mahmoud Mi
- Mahmoud S
- Mahmoud Sme
- Mahmud K
- Maillot B
- Maimbo M
- Maimbo M
- Mairs Ng
- Maison K
- Maistry N
- Majauskyté
- Majbar A
- Majid Ahha
- Majid K
- Major Cp
- Major P
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- Mak T
- Mak T
- Makama J
- Makinde M
- Makupe A
- Malavenda M
- Malik K
- Malik P
- Malik Ta
- Mamdouh E
- Mamdouh R
- Manatakis Dk
- Manfreda S
- Mangan C
- Mangan C
- Mangiapane M
- Manipal Ce
- Maniscalco A
- Mann T
- Mannu Gs
- Manriquez-Reyes M
- Mansor Ey
- Mansour B
- Mansour S
- Mansuri A
- Mao P
- Mapasse D
- Maple N
- Maraie N
- Marey A
- Marey As
- Margaritis M
- Mariani A
- Marinkovic B
- Marinos C
- Marks E
- Marples L
- Marret Jb
- Marshall Dc
- Martian Bv
- Martin A
- Mas R
- Mason C
- Mata Lps
- Matheu A
- Mathew Sw
- Matos-Puig R
- Matta Jjh
- Mattar O
- Matter Sm
- Mauro L
- Mayasari M
- Mazelyte R
- Mazrimas P
- Mazzella A
- Mcaleer E
- Mcaleer S
- Mccarthy K
- Mccarthy M
- Mccarthy M
- McCullagh D
- Mcdonald R
- McGarvie S
- Mcguigan A
- McIntosh K
- Mcintosh R
- Mcintyre Cj
- Mcintyre N
- Mcintyre R
- Mckechnie D
- Mclachlan G
- Mclean Al
- Mclean K
- McMorran D
- Mcnish D
- Mcphee A
- Mealy K
- Mehdi A
- Mehrez S
- Mejia Agv
- Melo R
- Melo R
- Mendel H
- Mendez M
- Mendez N
- Mendizabal Caa
- Mendoza I
- Menegussi J
- Mensah E
- Menshawy A
- Mentula P
- Meqbil J
- Mericliler M
- Merlini D
- Merlini D
- Merlo Ms
- Mesbah N
- Meshref A
- Metwally Mm
- Migliore M
- Miguel Gps
- Mihaljevic Al
- Mihanovic J
- Mihanovic J
- Mijuskovic B
- Mikalauskas S
- Mikalauskas S
- Mikuckyte D
- Mikwar Z
- Milligan W
- Milligan W
- Mingrone P
- Minguez G
- Minocha A
- Minocha A
- Miranda C
- Mircea H
- Mirghani D
- Mironescu A
- Mironescu A
- Mironescu As
- Mironescu As
- Mirza A
- Mirza S
- Mistry A
- Mitrasinovic S
- Mitroudi M
- Mitroudis N
- Mittal A
- Mitul Ar
- Mitul Ar
- Miyasato Hs
- Mizzi C
- Mizzi S
- Mlotshwa M
- Moaty M
- Mochet S
- Modolo Mm
- Modolo Mm
- Modolo Mm
- Moe Tt
- Mogan Yp
- Moghazy Me
- Mohamed A
- Mohamed A
- Mohamed Am
- Mohamed Ar
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed Ma
- Mohamed Maeh
- Mohamed Mm
- Mohamed O
- Mohamed Sr
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
- Mohammed A
- Mohammed Ae
- Mohammed Ar
- Mohammed H
- Mohammed Mm
- Mohammed Mmh
- Mohammed S
- Mohan H
- Mohan M
- Mohan M
- Mok Yt
- Mokhtar A
- Molina G
- Mollo Mc
- Monaghan E
- Monaghan E
- Monrad-Hansen Pw
- Montejo Msg
- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
- Moore R
- Mora Jjv
- Morais Pab
- Morales C
- Moran Aer
- Morandi E
- Moreira G
- Moreno Sc
- Morgan C
- Morgan C
- Morshedy Em
- Morsi A
- Morsi M
- Morton D
- Morton D
- Morton R
- Mosad A
- Mosalum O
- Mostafa Ha
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
- Mphatsoe Am
- Mshelbwala P
- Msiska N
- Msosa V
- Msosa V
- Muddebihal U
- Mukin Adf
- Muktar U
- Mukuzunga C
- Muller C
- Muller C
- Munera A
- Munhoz Mm
- Munipalle Pc
- Muntean L
- Muntean Li
- Muralha N
- Murphy J
- Murray A
- Murutoglu B
- Musa Aek
- Musleh A
- Musowoya J
- Mussad A
- Mustafa M
- Mustafa M
- Mustafa Ma
- Musyoka Ck
- Mutabazi Az
- Mutabazi Az
- Mutlu D
- Mutlu V
- Muzio E
- Myers J
- Mykoniatis I
- Næ
- Nabawi A
- Nada F
- Nadeem N
- Nadkarni S
- Nagy Gs
- Nahar Sn
- Nair H
- Nanthakumaran S
- Napolitano L
- Napolitano L
- Naqvi Sa
- Naqvi T
- Naranjo Aristizã
- Narayanan R
- Narayanan R
- Narvestad Jk
- Nashaat A
- Nashat M
- Nasher O
- Nashidengo P
- Nasir A
- Nasir Aa
- Nasr A
- Nasr M
- Nasr M
- Nassif D
- Nastri G
- Natalie H
- Nataraja R
- Natili A
- Navarro A
- Nawara C
- Nawawi A
- Nawawi A
- Nayel Ar
- Nazir M
- Ndajiwo A
- Ndajiwo A
- Ndegwa W
- Ndlovu Sr
- Ndwambi P
- Ne&apos
- Negida A
- Negoi I
- Nel D
- Nemeth K
- Neo Yn
- Neo Yt
- Neophytou C
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nesaratnam A
- Nessa A
- Nestorovic M
- Nevieraite V
- Newton T
- Ng S
- Ng Yk
- Ng Zh
- Ngayu N
- Ngwa Te
- Niazi Ak
- Nicholson L
- Nighat B
- Nigo S
- Nikberg M
- Nikoloudis N
- Nikoloudis N
- Niragire A
- Niranjan N
- Nirumal Mk
- Niska K
- Nita Ge
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- Niyirera E
- Njokanma I
- Nnajiuba H
- Nocito A
- Nocito A
- Nofal E
- Noor F
- Normile C
- Normile C
- North As
- Notarnicola M
- Notarnicola M
- Nouh T
- Nouh T
- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana Vjp
- Nsengiyumva C
- Ntirenganya F
- Nur&apos
- Nurqistan Hd
- Nwabuoku E
- Nwinee V
- Nwokoro C
- Nyberg J
- Nymo L
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- Obute Rd
- Occhionorelli S
- Odeyemi B
- Odeyemi B
- Odutola O
- Ogunsua O
- Ogunyemi A
- Oh J
- Oh J
- Ohene-Yeboah M
- Ojeda Rrb
- Okenabirhie O
- Olajide To
- Olaolorun A
- Olivier J
- Olori S
- Olori S
- Oludara M
- Oludara M
- Olugbemi M
- Omar Aa
- Omar Me
- Omar Mfw
- Omara S
- Omer Oa
- Onimowo J
- Onuoha C
- Oosterkamp A
- Opoku-Agyeman R
- Oram S
- Orbegozo Pat
- Orchard M
- Ortega I
- Ortega I
- Ortega-Vazquez I
- Ortiz N
- Orton P
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- Osei-Nketiah S
- Oshati O
- Oshodi O
- Osinowo A
- Osinowo A
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- Osman N
- Osman O
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- Oswald D
- Otero-Dí
- Othman M
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- Oumer R
- Owen C
- Owusu F
- Owusu F
- Ozben V
- Ozkan Bb
- Ozkan Bb
- Ozkan Bb
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- Paž
- Pabla G
- Pacheco Rda
- Padmore G
- Pagano G
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- Pagnozzi J
- Pahlsson Hi
- Pai S
- Palayan K
- Palkhi Eya
- Palliyil M
- Palliyil Mm
- Palma A
- Palma Af
- Paludi Ma
- Paludi Ma
- Panait N
- Panez Wr
- Panieri E
- Panteli C
- Papageorgiou D
- Papailia A
- Papandrea M
- Papaskarlatos Ia
- Pape J
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- Parakh J
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- Parasyris S
- Pardo G
- Parent V
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- Parmentier B
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- Parreno-Sacdalan Md
- Parseliunas A
- Parthiban S
- Pascale G
- Pascale Mm
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- Pasquali S
- Pastora J
- Pata D
- Pata D
- Pata F
- Pata F
- Pata F
- Pata F
- Pata F
- Pata F
- Pata G
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- Patoulias I
- Paul M
- Paul S
- Paulouski D
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- Pektaş
- Pellino G
- Peltrini R
- Pereira B
- Perenyei M
- Perera J
- Perera J
- Periasammy D
- Perino M
- Peros G
- Perrotta G
- Pesenti G
- Petrikenas S
- Peycelon M
- Peycelon M
- Pezas T
- Pezas T
- Pezelj N
- Phillips N
- Picardo A
- Picciariello A
- Pimenta Ml
- Pineñ
- Pinkney T
- Pinkney Td
- Pinnagoda K
- Pino W
- Pitt Sk
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- Pluke K
- Poš
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- Popa M
- Popoola A
- Popoola A
- Porter J
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- Poskus T
- Poskus T
- Poskus T
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- Powell A
- Pozo Dar
- Prabhudesai A
- Pranevicius R
- Prasad Ss
- Preckailaite E
- Primavesi F
- Prins M
- Proctor Vk
- Pronin S
- Prudhomme T
- Psaila J
- Psarianos K
- Psarianos K
- Pugliesi Tb
- Pujol-Cano N
- Puma Cmh
- Punja V
- Purwaningsih Na
- Puttick M
- Puttick M
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- Qawasmi I
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- Quayle J
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- Quezada Jhj
- Qumbos Aa
- Qureshi Au
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- Radkowiak D
- Radojkovic M
- Rahantasoa Fcfp
- Rahmah Df
- Rahmawati Fn
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- Rajmohan S
- Rakauskas R
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- Ramadan Mt
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- Rashad M
- Rashed Am
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- Rashwan H
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- Raslan C
- Rasoaherinomenjanahary F
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- Rausa E
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- Rayne S
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- Raza A
- Raza I
- Raza I
- Razek T
- Razmdjou S
- Razuri C
- Razzaque J
- Reali C
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- Recinos G
- Recinos G
- Recinos G
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- Redgrave N
- Redota Map
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- Renaux-Petel M
- Restrepo Im
- Restrepo J
- Reunis E
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- Riente F
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- Ripa M
- Riswan Nz
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- Roche Mo
- Rocke A
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- Rodriguez X
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- Runigamugabo E
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- Saad Ha
- Saad M
- Saad Mm
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- Sabour Fa
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- Safa H
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- Sahel S
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- Salah O
- Salah Om
- Salama M
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- Salleh A
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- Sallinen V
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- Salma M
- Salma M
- Salma U
- Salman A
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- Sam Zh
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- Samaniego Cs
- Samaraweera Di
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- Sammarco G
- Sammut K
- Sampson C
- Samson G
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- Sanz S
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- Schivo D
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- Senanayake Kj
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- Septiem Jg
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- Shahbaz Ar
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- Shaikh N
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- Shalabi A
- Shalaby A
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- Shamsedine Aw
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- Shehata S
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- Sigurdadottir J
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- Sodde P
- Soeselo Da
- Sokratous A
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- Soldevila-Verdeguer C
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- Srinivasan R
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- Sundstrom Sm
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- Tansoker I
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- Urbonas T
- Urbonas T
- Urniež
- Urniezius Z
- Urquizu Mc
- Usaityte A
- Utter M
- Uzabumwana N
- Vaicius A
- Valcarcel-Saldañ
- Valioulis I
- Van Der Naald N
- Van Duren B
- Van Niekerk M
- Van Straten S
- Varcada M
- Vargas M
- Varkalys K
- Vartanoglu T
- Vartic M
- Vartic M
- Vasquez G
- Vasquez I
- Veen T
- Vega Gmm
- Vega Gmm
- Velá
- Velá
- Velasquez R
- Vella-Baldacchino M
- Venclauskas L
- Vendramin E
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venugopal C
- Verbeek A
- Vergara Alc
- Verjee A
- Vermaas M
- Veronese E
- Viš
- Vianna P
- Vicario E
- Vico Td
- Vida Lc
- Vida Lc
- Vilč
- Villa R
- Villalobos S
- Villegas Mi
- Vimalachandran D
- Vincent J
- Violi P
- Vivekanantham S
- Vlachogiorgos A
- Voulgaris E
- Vth Le
- Wael N
- Wagener M
- Wakefield R
- Walę
- Waleed H
- Walker M
- Walker N
- Walls L
- Walsh M
- Walsh U
- Waqar M
- Ward Ae
- Ward S
- Warda M
- Warren O
- Warren O
- Warwick Am
- Waterman A
- Watson Nf
- Watts A
- Weber B
- Weber P
- Weber P
- Weinstein Ms
- Werder G
- Wheeler J
- Whewell H
- Whitaker J
- White R
- White T
- Whitehurst K
- Wiborg J
- Widiastini Ta
- Widmer Lw
- Wijayarathna Ls
- Wild Jrl
- Williams E
- Williams G
- Williams O
- Williams O
- Williamson A
- Wilson A
- Wilson L
- Wilson M
- Wilson M
- Wilson Ms
- Wilson Msj
- Wimalge Pmsn
- Winstanley J
- Witherspoon P
- Wogensen F
- Wogensen F
- Wogensen F
- Woin E
- Wold Tb
- Wolf B
- Wolf B
- Wondimu S
- Wondoh P
- Wondoh P
- Wong Cs
- Wong Cy
- Wong F
- Wong Hy
- Wood G
- Woodward H
- Worku M
- Worku M
- Worku T
- Wredberg C
- Wright N
- Wright Nj
- Xerri T
- Xerri T
- Yahaya Mt
- Yakubu M
- Yallop L
- Yam Sy
- Yang J
- Yap S
- Yaseen T
- Yaseen Tm
- Yau Jd
- Yavuz Ma
- Ye J
- Yeang Lj
- Yee J
- Yeo Ls
- Yeung En
- Yeung Mha
- Yifieyeh A
- Yildirim R
- Yip C
- Yip Sbs
- Ymeri S
- Yoganathan P
- Yolcu S
- Yong Co
- Yong Gl
- Younis A
- Youssef D
- Youssef H
- Youssef M
- Youssif Jh
- Yuksek Ma
- Yusufali T
- Zaa&apos
- Zachariades Dc
- Zadoroznas A
- Zahran D
- Zakaria E
- Zakaria M
- Zakaria Y
- Zaki A
- Zakir M
- Zalabia Mf
- Zamarin K
- Zammit S
- Zampitis N
- Zani A
- Zani A
- Zani A
- Zanini N
- Zanini N
- Zapata F
- Zarb C
- Zardab A
- Zegarra S
- Zeidan S
- Zerihun Ab
- Zhang Z
- Zheng F
- Zidan H
- Zidan H
- Zidan M
- Zielinski M
- Ziff O
- Zikry M
- Zil-E-Ali A
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zimmermann Ef
- Zohair A
- Zorrilla Cd
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbü
- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
Quality indicators in pork meat from different commercial center of Ciudad Obregón, Sonora (México)
- Publication venue
- 'Universidad Autonoma Metropolitana'
- Publication date
- 01/12/2017
- Field of study
The demand for safety food with high quality has been increased in recent years. Meat properties (color, texture, firmness) are related to the previous products handle before being consumed. The objective of this work was to determinate the physicochemical characteristics of pork in different commercial centers in Ciudad Obregon (Mexico). 50 meat samples were taken from 10 different commercial centers. Water holding capacity (WHC), drip loss (DL), and instrumental color in CIELab coordinates. For the shear strain the methodology of Warner-Bratzler shear blade was employed. Results for WHC were 84.44± 0.918%, DL24h was 6.84 ± 3.09%, and DL48h of 8.12±3.80%. Color obtain luminosity values L* of 48.97±4.20, redness a* of 3.95±1.15, and yellowness b* of 11.22±0.49, hue of 71.45±5.77 and chroma of 14.86±6.50. Shear strain in all samples was in the range of 3.03±0.39 kgf and a pH of 5.937±0.114. No significantly difference between samples commercial centers was found. Nonetheless, the localization of point of sale could influence in function of quality
A retrospective analysis of ethnic and gender differences in alcohol consumption among emergency department patients: a cross-sectional study
- Author
- AC Love
- BA Mills
- Bharath Chakravarthy
- Christopher Eric McCoy
- CJ Cherpitel
- Craig L. Anderson
- Cristobal Barrios
- DA Dawson
- DD Satre
- DG Blazer
- DS Timberlake
- E Bernstein
- EE Bouchery
- F Vaca
- FE Vaca
- FH Galvan
- JB Saunders
- JP Allen
- K Chartier
- KM Keyes
- KM Keyes
- Kristin Alix
- M Stahre
- MJ Bohn
- MJ Paschall
- MM Maldonado-Molina
- R Caetano
- RM Crum
- RW Wilsnack
- S Lotfipour
- S Lotfipour
- S Lotfipour
- S Lotfipour
- SE Zemore
- Shahram Lotfipour
- Uzor C. Ogbu
- Victor Cisneros
- Wirachin Hoonpongsimanont
- World Health Organization
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Effect of Essential Fatty Acid Proportion in Feed on Productive and Reproductive Performance of Japanese Quail (Coturnix coturnix japonica)
- Author
- Al-Daraji HJ
- Alessandri JM
- Arantes da Silva W
- Barceló-Coblijn G
- Baucells MD
- Betancourt L
- Blesbois E
- Bongalhardo DC
- Calder PC
- CB Castro-Tamayo
- Chen TF
- Cherian G
- Cherian G
- Cherian G
- Dalton MN
- FG Rios-Rincón
- Folch J
- G Contreras-Pérez
- Güçlü BK
- Hagger C
- Herstad O
- Hulan HW
- JB Heredia
- Jing M
- JJ Portillo-Loera
- Lucotte G
- Manohar GR
- Mao JNC
- MDI Muy-Rangel
- Mennicken L
- Mexican NO
- Mexican NO
- Minvielle F
- Moir KW
- Morales-Barrera J
- Nadia L
- Navas JM
- Neijat M
- Neumann KF
- RI Castillo-Lopez
- RM Molina-Barrios
- Rodríguez-Michel A
- Shamma TA
- Simopoulos AP
- Spector AA
- Zanini SF
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2020
- Field of study
Resistance to HIV Non-Nucleoside Reverse Transcriptase Inhibitors
- Author
- A Antinori
- A Jacobo-Molina
- A Koen
- A Lazzarin
- AJ Leigh Brown
- AL Hopkins
- AL Hopkins
- AMJ Wensing
- B Brenner
- BA Larder
- BH Chi
- C Apetrei
- C Delaugerre
- C Delaugerre
- C Mordant
- C Palaniappan
- CE Korval
- CL Booth
- D Descamps
- D Havlir
- D Pillay
- DD Richman
- DD Richman
- DD Richmann
- DG DeRequena
- DL Winslow
- DW Rodgers
- E Tuaillon
- EO Freed
- F Rodriguez-Barrios
- F Rodriguez-Barrios
- G Campiani
- G Jourdain
- G Tachedjian
- G Tachedjian
- GJ Hanna
- GR Painter
- H Huang
- H Loemba
- HJ Ribaudo
- J Ding
- J Ding
- J Ding
- J Gallant
- J Lindberg
- J Ren
- J Ren
- J Ren
- J Ren
- J Vingerhoets
- J Wang
- JA Bartlett
- JA Collins
- JB Jackson
- JM Coffin
- JM Whitcomb
- JP Kleim
- JV Madruga
- K Das
- K Das
- K Diallo
- K Rittinger
- L Bacheler
- L Morris
- LA Guay
- LA Kohlstaedt
- LM Demeter
- LM Demeter
- LT Batchelor
- LY Hsu
- M Ait-Khaled
- M Witvrouw
- MD Iglesias-Ussel
- ML Nolan
- N Shulman
- NA Margot
- NA Martinson
- NS Shulman
- NS Shulman
- NT Parkin
- OS Pedersen
- P Colson
- P Gerondelis
- P Musoke
- PAJ Janssen
- PJ Lewis
- PL Boyle
- PR Harrigan
- R Esnouf
- RA Archer
- RA Spence
- RH Haubrich
- RM Esnouf
- RM Esnouf
- RM Grant
- RM Gulick
- S Aquaro
- S Lockman
- S Palmer
- S Staszewski
- S Taylor
- S Y Rhee
- SA Clark
- SD Young
- SG Sarafianos
- SG Sarafianos
- SH Eschleman
- SH Eshleman
- SH Eshleman
- SH Eshleman
- SH Eshleman
- SJ Little
- SJ Smerdon
- SL Warmsley
- SY Rhee
- T Flys
- TD Toni
- The TMC-125 C223 Writing Group
- TJ Dueweke
- V Joly
- VA Johnson
- W Huang
- Y Gao
- Y Hsiou
- Y Hsiou
- Y Quan
- Z Grossman
- Z Grossman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2009
- Field of study
Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects.
- Author
- Abdulhakim Ee
- Abraham G
- Adamiec R
- Adler A
- Alpizar-Salazar M
- Altorjay A
- Andre I
- Anzà C
- Appolinario J
- Archambeaud F
- Armstrong P
- Astrup A
- Augusztin G
- Avezum A
- Baar M
- Babes A
- Banasiak W
- Barnett Ah
- Baro Fm
- Barrios Merino A
- Basdevant A
- Bednarova J
- Beermann J
- Bevilacqua M
- Bock M
- Bodmer C
- Boenner G
- Bogaty P
- Boland J
- Borras Jl
- Borys Jm
- Bosello O
- Bringer J
- Brohet C
- Brophy J
- Brunetiere C
- Bugan V
- Caixas A
- Campbell Iw
- Campbell L
- Carey D
- Carrageta M
- Carrillo-Ortega E
- Caterson Id
- Caterson Id
- Cencarik J
- Cepelak V
- Cerny P
- Charpentier G
- Chiariello M
- Chowdhury T
- Chrusciel P
- Cifkova R
- Cifkova R
- Cleland J
- Cocaul-André M
- Colquhoun D
- Colquhoun D
- Cook Rc
- Cordera R
- Costa e Forti A
- Costa e Forti A
- Coucke F
- Coutinho W
- Coutinho W
- Creteanu G
- Csala L
- Csaszar A
- Cuatrecasas Cambra G
- Czuriga I
- Dabadie H
- Dagenais G
- Dammann Hg
- Dan Ga
- de Albuquerque Dc
- de Godoy Matos Af
- de la Torre Casares Ml
- Dendale P
- Derlaga B
- Di Mario U
- Diehm C
- Dinneen S
- Dinnyes J
- Ditschuneit H
- Dominguez Escribano Jr
- Dominguez H
- Donnachie H
- dos Santos L
- Dragulescu Si
- Drexler H
- Dubreuil A
- Duran Garcia S
- Escobar-Jimenez L
- Esteva de Antonio I
- Estour B
- Fabbri G
- Faber J
- Fanghanel Salmon G
- Farsky S
- Ferrannini E
- Ferrannini E
- Ferrari E
- Finer N
- Finer N
- Formiguera Sala X
- Frittitta L
- Gadow J
- Galli M
- Garcia Robles R
- Garcia-Luna Pp
- Gautier Jf
- Gebala A
- Gehlhar S
- Gero L
- Gerstman M
- Gessek J
- Gessner S
- Gibault T
- Giorgino R
- Gonsorcik J
- Gonzalez Albarran O
- Gonzalez C
- Gonzalez C
- Graur M
- Gross Jl
- Guthersohn A
- Gyimesi A
- Hainer V
- Halimi S
- Halmy L
- Halmy L
- Halpern A
- Hamann A
- Hancu N
- Hancu N
- Hanefeld M
- Hasenfuss G
- Haslam Dw
- Havranek P
- Hernandez-Mijares A
- Herzner A
- Hespel Jp
- Heufelder Ae
- Heun Kc
- Hildebrandt P
- Hilderbrant P
- Hillis Gs
- Hohensee H
- Hollanders G
- Hollanders G
- Homza M
- Horne M
- Howarth Dj
- Hughes E
- Issa Sayegh M
- Jackson S
- Jacob S
- James Wp
- James Wp
- Janik K
- Janion M
- Janosi A
- Jansa P
- Jones Sc
- Jones Th
- Jordan J
- Jordan J
- Jouret G
- Kalina Z
- Kamensky G
- Karlicek M
- Karrasch J
- Kerr Saraiva Jf
- Kerr D
- Kmec J
- Kober L
- Kolanowski J
- Kolesar J
- Kotik I
- Kovacs I
- Kozlowski A
- Krahulec B
- Krempf M
- Krings P
- Krosse B
- Krätzig B
- Kucera D
- Kucera D
- Kuchar J
- Kumar S
- Kunc M
- Kurian R
- Kusnierz B
- Kutnowski M
- Kvapil M
- Laviada-Molina Ha
- Laville M
- Lean M
- Lecerf Jm
- Lefkovits J
- Lehmann Rt
- Linhart A
- Liuzzi A
- Liziczai I
- Louvet Jp
- Macek V
- Machova V
- Madero Ma
- Maggioni Ap
- Maggioni Ap
- Maisch B
- Majcher Z
- Majercak I
- Majtenyi A
- Malinverni C
- Mann J
- Marks J
- Marks S
- Maroni J
- Martens F
- Martin Hidalgo A
- Masmiquel Comas L
- Matuska J
- Mcinnes G
- Medvegy M
- Melchionda N
- Mendes Pedro Mm
- Micko K
- Middleton A
- Miekus P
- Milagres R
- Mindt-Prüfert S
- Mokan M
- Morales Perez F
- Moreno Esteban B
- Morosanu M
- Morris A
- Moses R
- Mota M
- Muls E
- Nadhazi Z
- Narkiewicz K
- Narkiewicz K
- Newcombe G
- Niegowska J
- O'Kane Kp
- Occhi G
- Okopien B
- Oral I
- Ostergren J
- Ostrowska L
- Pados G
- Parente Martins Lm
- Pascual Izuel Jm
- Pascual J
- Pasowicz M
- Pavel Ic
- Paveliu Fs
- Pavlas J
- Pawa R
- Payer J
- Peiffer F
- Penfornis A
- Penninckx H
- Pepine C
- Perrild H
- Perry C
- Perticone F
- Pesatova S
- Pfeiffer Af
- Phillips P
- Piepiorka M
- Pinchera A
- Pinelli G
- Pitts C
- Pluta W
- Pocock S
- Polak G
- Polaszewska-Muszynska M
- Ponikowski P
- Povolny J
- Proietto J
- Pupek-Musialik D
- Radoi M
- Raja A
- Ranetti A
- Reckless J
- Redon Mas J
- Renz Cl
- Repetto G
- Ricart W
- Richard F
- Richelsen B
- Riecansky I
- Ritz P
- Roberts D
- Roberts-Thomson P
- Robinson J
- Rode Ra
- Rodriguez G
- Ronaszeki A
- Rose B
- Rovera G
- Rubio Ma
- Ruilope Lm
- Salas-Salvado J
- Saldate C
- Sanchez-Castillo Cp
- Santeusanio F
- Santini F
- Sarmiento R
- Sawicki A
- Scheen A
- Scherbaum Wa
- Scherbaum Wa
- Schlienger Jl
- Schmidt E
- Schmitt B
- Scholze J
- Schoors D
- Schreckenberg A
- Semrad B
- Sharma Am
- Sharma Am
- Shaw J
- Shepherd Gm
- Sherman D
- Sido Z
- Simon K
- Simpson R
- Singh B
- Singleton Jeffries W
- Sleight P
- Smetana K
- Sobocik H
- Sogaard P
- Sojka G
- Soo Sc
- Soucek M
- Stankiewicz A
- Stuckey B
- Stuebler P
- Suplicy Hl
- Svacina S
- Svendsen Ol
- Swedberg K
- Szpajer M
- Taylor S
- Terroba Larumbe M
- Tesinsky P
- Thomas Ho
- Thomson Ma
- Tinahones F
- Tirgoviste Ci
- TORP-PEDERSEN C
- Torp-Pedersen C
- Totoian I
- Toubro S
- Toubro S
- Trojnar R
- Tykarski A
- Uhliar R
- Urbanek R
- Urbinati S
- Urgeova L
- Urhammer S
- Vaerenberg M
- Valensi P
- Van Cleemput J
- Van Crombrugge P
- VAN GAAL Lf
- Van Gaal Lf
- Van Kuyk M
- Vancik J
- Verhaegen A
- Vidal Cortada J
- Violante Rm
- Wacher N
- Walter J
- Wasserburger B
- Wilding J
- Wilding J
- Wilkins M.
- Wirth A
- Wollaert B
- Wrabec K
- Wunderlich J
- Wyrzkowski B
- Zachoval R
- Zahorska-Markiewicz B
- Zahumensky E
- Zalewski M
- Zanella Mt
- Zannad F
- Zayas-Jaime Fj
- Zidkova E
- Ziegler O
- Ziegler O
- Zuniga-Guajardo S
- Zuniga-Perez Lemaur M
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2010
- Field of study
BACKGROUND: The long-term effects of sibutramine treatment on the rates of cardiovascular events and cardiovascular death among subjects at high cardiovascular risk have not been established. METHODS: We enrolled in our study 10,744 overweight or obese subjects, 55 years of age or older, with preexisting cardiovascular disease, type 2 diabetes mellitus, or both to assess the cardiovascular consequences of weight management with and without sibutramine in subjects at high risk for cardiovascular events. All the subjects received sibutramine in addition to participating in a weight-management program during a 6-week, single-blind, lead-in period, after which 9804 subjects underwent random assignment in a double-blind fashion to sibutramine (4906 subjects) or placebo (4898 subjects). The primary end point was the time from randomization to the first occurrence of a primary outcome event (nonfatal myocardial infarction, nonfatal stroke, resuscitation after cardiac arrest, or cardiovascular death). RESULTS: The mean duration of treatment was 3.4 years. The mean weight loss during the lead-in period was 2.6 kg; after randomization, the subjects in the sibutramine group achieved and maintained further weight reduction (mean, 1.7 kg). The mean blood pressure decreased in both groups, with greater reductions in the placebo group than in the sibutramine group (mean difference, 1.2/1.4 mm Hg). The risk of a primary outcome event was 11.4% in the sibutramine group as compared with 10.0% in the placebo group (hazard ratio, 1.16; 95% confidence interval [CI], 1.03 to 1.31; P=0.02). The rates of nonfatal myocardial infarction and nonfatal stroke were 4.1% and 2.6% in the sibutramine group and 3.2% and 1.9% in the placebo group, respectively (hazard ratio for nonfatal myocardial infarction, 1.28; 95% CI, 1.04 to 1.57; P=0.02; hazard ratio for nonfatal stroke, 1.36; 95% CI, 1.04 to 1.77; P=0.03). The rates of cardiovascular death and death from any cause were not increased. CONCLUSIONS: Subjects with preexisting cardiovascular conditions who were receiving long-term sibutramine treatment had an increased risk of nonfatal myocardial infarction and nonfatal stroke but not of cardiovascular death or death from any cause. (Funded by Abbott; ClinicalTrials.gov number, NCT00234832.
Microalgae cultivation for phenolic compounds removal
- Author
- A Balasubramanian
- A Banerjee
- A Barrios-Martinez
- A Converti
- A Demirbas
- A Martino De
- A Papazi
- A Papazi
- A Papazi
- A Richmond
- A Salmerón-Alcocer
- A Viggiani
- A Vonshak
- AG Fontes
- Agency for Toxic Substances and Disease Registry (ATSDR)
- AH Al-Muhtaseb
- AJ Dassey
- AP Batista
- B Das
- B Das
- B Lai
- B Wang
- BH Diya’uddeen
- C Chen
- C Iaconi Di
- C Li
- C Safi
- C Védrine
- C-Y Chen
- C. J. Soeder
- CM Gatenby
- CR Jones
- CR Lovell
- D Arya
- D Hoh
- D Li
- D Mamma
- D Puyol
- D Tang
- D Vandamme
- D Xie
- DE Terlizzi
- DL Nelson
- E Molina Grima
- E Razo-Flores
- EB Estrada-Arriaga
- F Fava
- F Ozyonar
- F-LE Chu
- G Baggi
- G González
- G Pinto
- G Torzillo
- G-M Zhou
- GS Costard
- H Liu
- H Yao
- H-Y Ren
- I Fernández
- I Rawat
- I Visviki
- I Vázquez
- J Cao
- J Dosta
- J Doucha
- J Fabregas
- J Michałowicz
- J Winkler
- J Yan
- J Yan
- J Yang
- J Zhou
- JA Padilla-Sánchez
- JE Bailey
- JK Pittman
- JM Sandnes
- JN Whyte
- K Cho
- K Lika
- K Pakshirajan
- K Tsekova
- K-L Ho
- KA Khan
- KH Ogbonda
- KT Semple
- KT Semple
- L Altaş
- L Brennan
- L Chen
- L Damjanović
- L Levén
- L Wang
- L Wang
- L Wang
- L Wang
- L Xin
- L Zhu
- L-S Zhang
- M Cea
- M Ceron Garcia
- M Taraldsvik
- M Vargas
- M-K Ji
- M-K Ji
- MA Al-Obaidi
- MD Greca
- MH El-Naas
- MH El-Naas
- MH El-Naas
- MM El-Sheekh
- MR Bilad
- MR Brown
- MR Brown
- MR Brown
- MTA Reis
- N Uduman
- NK Pazarlioğlu
- O Abdelwahab
- O Abdelwahab
- OJ Hao
- P-T Huong
- PS Majumder
- R Bouterfas
- R Canizares-Villanueva
- R Ramanan
- R Surkatti
- R. Surkatti
- RF Sena De
- Riham Surkatti
- RK Singh
- RM Knuckey
- RM Knuckey
- RO Cristóvão
- RS Dobson
- S Aaronson
- S Al-Zuhair
- S Al-Zuhair
- S Boussiba
- S Chakraborty
- S Chinnasamy
- S Dayana Priyadharshini
- S Mohamad
- S Naoki
- S Rahim Pouran
- S Sanjeev Kumar
- S Wahidin
- S-Y Chiu
- S-Y Chiu
- S-Y Tsai
- SAC Lima
- Senthil Chinnasamy
- SG Thakurta
- SM Renaud
- SS Bhattacharya
- Sulaiman Al-Zuhair
- T Al-Khalid
- T Hirooka
- T Hirooka
- TM Mata
- TS Sim
- V Andrulevičiūtė
- V Klekner
- V Klekner
- W Ngarmkam
- W-B Kong
- WY Cheah
- Y Chenl
- Y Chisti
- Y Jiang
- Y Kitaya
- Y Li
- Y Li
- Y Lu
- Y Wang
- Y-M Chen
- Z Amini Khoeyi
- Z She
- Z Wei
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Mortality after surgery in Europe: a 7 day cohort study
- Author
- Aakeroey K
- Acan I
- Adams D
- Adams T
- Adanic M
- Adolfsson A
- Afonso O
- Afshari A
- Agarwal B
- Agnic I
- Aguado DN
- Ahern R
- Ahonen T
- Aignatoaie M
- Akotia N
- Akouds E
- Al Abdaly A
- Al Subaie N
- Alagarsamy F
- Alameda LE
- Alaspää A
- Albalad DD
- Albaladejo P
- Albante A
- Alberdi F
- Albu C
- Alcaide CM
- Alcantud JF
- Aldecoa C
- Aldecoa C
- Alderson L
- Aleixandre IS
- Aleksic D
- Aleman M
- Alexander D
- Alexander P
- Algarra RR
- Ali ZS
- Aliste P
- Allué RM
- Almeida E
- Almeida IM
- Almeras L
- Alonso AE
- Alonso E
- Alvarez AA
- Alvarez LR
- Amaniti E
- Amatya S
- Ampuero MS
- Anchuelo AH
- Andabaka T
- Andersen JD
- Anderson H
- Andresen B
- Angulo GO
- Anna US
- Anthopoulos G
- Antolinos MA
- Apsokardos A
- Aracil N
- Aranzubia M
- Arawwawala D
- Arcas JJ
- Arevalo J
- Argente GR
- Arif F
- Armaganidis A
- Armaganidis A
- Arnaoutoglou E
- Arnold G
- Arocas B
- Arpino I
- Arroyo MM
- Arteta DA
- Artigas A
- Artigas X
- Arvaniti K
- Arviza LP
- Asensio MA
- Assunção JP
- Aubrun F
- Auer P
- Austine P
- Aversano M
- Awlakpui E
- Axelsson P
- Ayman M
- Baban O
- Bacak Kocman I
- Bacci A
- Baciu M
- Baddeley S
- Bailey K
- Baker A
- Baker J
- Bakosova E
- Balaji P
- Balasa C
- Balciscueta G
- Balenovic I
- Ball C
- Ballington R
- Balust C
- Balust J
- Bandic D
- Baraldi S
- Baranovic S
- Barber R
- Barbes A
- Baricocchi E
- Barižon M
- Baroselli A
- Barr K
- Barrachima BB
- Barrasa H
- Barrios F
- Barrios J
- Barros F
- Barros N
- Barthel F
- Bartolomé MJ
- Bataillard A
- Batchelor N
- Bates D
- Batinica IM
- Battistella M
- Bauer P
- Bauer W
- Bauer ZŠ
- Baumgarten R
- Baxter I
- Bazin M
- Beach M
- Becanne X
- Beck O
- Beckingsale A
- Bekos V
- Belavic M
- Belcher A
- Belciu I
- Belenguer Muncharaz A
- Belhaj A
- Belikova B
- Bellotti F
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- Benayoun L
- Bento HC
- Bento L
- Bergamini E
- Berger K
- Berger P
- Bergin A
- Bermejo FJ
- Bernal DG
- Bernat Álvarez MJ
- Berneanu M
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- Bestle M
- Betancor NO
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- Bešlic G
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- Blauwen Nd
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- Castiñeiras AP
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- Cupitt J
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- DELLA CORTE Francesco
- Della Rocca G
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- Dennesen P
- Derumeaux P
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- Di Mauro P
- Di Noto A
- Diaconescu C
- Diaz A
- Diaz Boladeras RM
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- Dinescu SA
- Dinu M
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- Divander MB
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- Djordjevic B
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- Dragoumanis C
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- Dražen B
- Drenjancevic IH
- Drescher J
- Dresden C
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- Yemnga B
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- Zabarte M
- Zacharouli D
- Zacharovska A
- Zadrazilova K
- Zafiridis T
- Zahorec R
- Zahorec R
- Zaldibar E
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- Zantua K
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- Zompanti V
- Zsisku L
- Zunic F
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- Álvaro JL
- Ålvarez JT
- Íñigo JA
- Šakic K
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2012
- Field of study
Background: Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe.Methods: We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used χ² and Fisher’s exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at p<0·05. We constructed multilevel logistic regression models to adjust for the differences in mortality rates between countries.Findings: We included 46 539 patients, of whom 1855 (4%) died before hospital discharge. 3599 (8%) patients were admitted to critical care after surgery with a median length of stay of 1·2 days (IQR 0·9–3·6). 1358 (73%) patients who died were not admitted to critical care at any stage after surgery. Crude mortality rates varied widely between countries (from 1·2% [95% CI 0·0–3·0] for Iceland to 21·5% [16·9–26·2] for Latvia). After adjustment for confounding variables, important differences remained between countries when compared with the UK, the country with the largest dataset (OR range from 0·44 [95% CI 0·19 1·05; p=0·06] for Finland to 6·92 [2·37–20·27; p=0·0004] for Poland).Interpretation: The mortality rate for patients undergoing inpatient non-cardiac surgery was higher than anticipated. Variations in mortality between countries suggest the need for national and international strategies to improve care for this group of patients.Funding: European Society of Intensive Care Medicine, European Society of Anaesthesiology