44 research outputs found
Syntax highlighting as an influencing factor when reading and comprehending source code
Syntax highlighting or syntax colouring, plays a vital role in programming development environments by colour-coding various code elements differently. The supposition is that this syntax highlighting assists programmers when reading and analysing code. However, academic text books are largely only available in black-and-white which could influence the comprehension of novice and beginner programmers. This study investigated whether student programmers experience more difficulty in reading and comprehending source code when it is presented without syntax highlighting. Number of fixations, fixation durations and regressions were all higher for black-and-white code than for colour code but not significantly so. Subjectively students indicated that the colour code snippets were easier to read and more aesthetically pleasing. Based on the analysis it could be concluded that students do not experience significantly more difficulty when reading code in black-and-white as printed in text books
Making A Difference: Year Two Report of the Pennsylvania High School Coaching Initiative
This report examines the implementation of the second year of three for the Pennsylvania High School Coaching Initiative (PAHSCI). Funded by the Annenberg Foundation, this initiative focuses on literacy and math coaches providing support to teachers from across the major subject areas to create literacy-rich classrooms in which students actively engage in learning tasks that deepen their content knowledge and strengthen their abilities to think critically and communicate well. This report presents findings from the first two years of research. It includes survey research as well as in-depth qualitative research in participating schools and districts and provides recommendations for PAHSCI stakeholders as they refine the program and for other education reformers as they consider the benefits of instructional coaching as a strategy for improving high schools and student achievement
Standards in semen examination:publishing reproducible and reliable data based on high-quality methodology
Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen examination. Recently two concordant documents have been published: the 6th edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen, and the International Standard ISO 23162:2021. With these tools, we propose that authors should be instructed to follow these laboratory methods in order to publish studies in peer-reviewed journals, preferable by using a checklist as suggested in an Appendix to this article.Peer reviewe
Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).
Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)
Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362
Gathering the Kalahari: Tracking Landscapes in Motion
At a time when human environmental disturbance is challenging livability on the planet—for humans and nonhumans alike—it is important to find better methods for engaging with the liveliness of landscapes, the relations with which they hang together, and the various ways they are interrupted. This dissertation explores the practices of tracking and gathering as methods for studying such issues facing Kalahari Desert landscapes in Botswana. These ecologically important landscapes are increasingly encroached upon and fragmented by the growing cattle economy and the proliferation of extractive industries into the desert. These trends have led to dramatic declines in wildlife populations and growing desertification of the already arid region. The Kalahari is home to small communities of people, many of whom are former hunter-gatherers whose rights to land and access to wildlife are increasingly inhibited. The government has banned hunting, largely in response to conservationists’ concerns about wildlife. In addition, gathering is increasingly regulated, and cattle colonize areas that are significant for wildlife and San communities. In this context, rather than treating tracking and gathering as objects of study, I take these practices seriously as methods for noticing and theorizing more-than-human landscapes, their transformations, and contingent histories to address challenges facing people and their environments in the Kalahari and beyond. By focusing on the relational forms of noticing landscapes with San trackers and gatherers, I describe landscapes as always in motion, emergent more-than-human places where assemblages gather, histories are made, and politics enacted. This is in direct contrast to theoretical moves that treat landscapes as background on which histories and politics occur. My dissertation enacts tracking and gathering as a methodology. Beginning with an extension of the concept of tracks and following their movements out to their relations with other landscape actors in each chapter, I emphasize that landscapes are not merely contexts for politics and histories. Rather, landscapes do histories and politics, in spite of efforts to hold these landscapes still as underutilized expanses of resources. The dissertation itself unfolds, moving out through the landscape by tracking these emergent relations. I argue that tracking is a relational practice of becoming-familiar-with these multiple entanglements of emergent landscapes. The practice of gathering involves much of the same kinds of attention to landscape movements and their coordinations as with tracking. Here, I employ gathering in its double meaning: the practice of collecting and of coming together. The tracks of gathered truffles then lead to the worlds of grass and termites that, in turn, allow for a reflection on Kalahari rangeland ecology and the political economy of the cattle industry. Finally, the dissertation zooms out to the desert’s geomorphology, tracking the movements of geological processes as they gather with the movements of humans and nonhumans to form lively landscape features over the longue duree. Tracking and gathering are methods that allow for an elaboration of these more-than-human landscapes-in-motion, together with their social, political, and economic histories and speculative futures
Performance of Distributed Bagged Stone Dust Barrier in Combating Coal-Dust Explosions
The Kloppersbos Research Facility of the CSIR\u27s Division of Mining Technology has developed a new method of building stone dust barriers. The new barrier makes use of a previous concept of containing stone dust in a bag, but incorporates a new method of rupturing the bag. This was achieved by adapting the closing mechanism and by balancing the stone dust content with the void in the bag. The bagged barrier was extensively tested in the 200-m test gallery. During these tests, it became evident that these bags could be made to rupture and spread stone dust when subjected to smaller forces than those required for the most commonly used passive barrier, the polish light barrier. To validate this, as well as to gain international acceptance of this new barrier, tests were conducted in the German experimental mine, DMT Tremonia, Dortmund. The barrier was evaluated against numerous methane-initiated coal-dust explosions. The paper describes the successful inhibition of coal-dust explosions at Kloppersbos and DMT Tremonia. The barrier has been proven successfully for static pressures of 44 to 82 kpa, dynamic pressures of 12 to 36 kpa and for flame speeds as low as 23 m/s. This barrier is now accepted by the South African government and has been implemented in numerous South African collieries