562 research outputs found
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alda Junior WL
- Alexander J
- Aliev T
- Almeida N
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- Alverson G
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- Anagnostou G
- Anastassov A
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- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
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- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
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- Zang SL
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- Zeuner WD
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- Zheng Y
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- Zhukov V
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- Ziebarth EB
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Voltage-Gated Ion Channel Dysfunction Precedes Cardiomyopathy Development in the Dystrophic Heart
- Author
- A Sadeghi
- AE Deconinck
- Agnes K. Mike
- AL Leoni
- B Bostick
- B Bostick
- B Gavillet
- C Colussi
- CG Au
- D Vaidya
- DM Pedrotty
- EM McNally
- Hannes Todt
- J Capote
- JG Quinlan
- JK Perloff
- JM Ervasti
- JN Muth
- K Bushby
- K Matsumura
- Karlheinz Hilber
- Katrin Nagl
- LF Torres
- LS Meadows
- M Albesa
- M Hesse
- M Mille
- M Yotsukura
- Marcello Rota
- MF Peters
- P Sicinski
- Peter Lukacs
- PM Janssen
- Reginald E. Bittner
- Rene Cervenka
- RM Grady
- RP Beynon
- S Sarma
- SA Thomas
- Sandra Dysek
- Stefanie Kimbacher
- T Aiba
- TA Hainsey
- TM Olson
- WP McNair
- Xaver Koenig
- Xuan B. Dang
- Y Ou
- Publication venue
- Public Library of Science
- Publication date
- 23/05/2011
- Field of study
Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is associated with severe cardiac complications including cardiomyopathy and cardiac arrhythmias. Recent research suggests that impaired voltage-gated ion channels in dystrophic cardiomyocytes accompany cardiac pathology. It is, however, unknown if the ion channel defects are primary effects of dystrophic gene mutations, or secondary effects of the developing cardiac pathology.To address this question, we first investigated sodium channel impairments in cardiomyocytes derived from dystrophic neonatal mice prior to cardiomyopahty development, by using the whole cell patch clamp technique. Besides the most common model for DMD, the dystrophin-deficient mdx mouse, we also used mice additionally carrying an utrophin mutation. In neonatal cardiomyocytes, dystrophin-deficiency generated a 25% reduction in sodium current density. In addition, extra utrophin-deficiency significantly altered sodium channel gating parameters. Moreover, also calcium channel inactivation was considerably reduced in dystrophic neonatal cardiomyocytes, suggesting that ion channel abnormalities are universal primary effects of dystrophic gene mutations. To assess developmental changes, we also studied sodium channel impairments in cardiomyocytes derived from dystrophic adult mice, and compared them with the respective abnormalities in dystrophic neonatal cells. Here, we found a much stronger sodium current reduction in adult cardiomyocytes. The described sodium channel impairments slowed the upstroke of the action potential in adult cardiomyocytes, and only in dystrophic adult mice, the QRS interval of the electrocardiogram was prolonged.Ion channel impairments precede pathology development in the dystrophic heart, and may thus be considered potential cardiomyopathy triggers
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
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- Wyslouch B
- Xiao H
- Xie S
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- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
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- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Azimuthal anisotropy of charged particles at high transverse momenta in PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Afanasiev S
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alcaraz Maestre J
- Alda Junior WL
- Alexander J
- Aliev T
- Alimena J
- Almeida N
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunovic Z
- Apanasevich L
- Appelt E
- Apresyan A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
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- Arora S
- Asawatangtrakuldee C
- Asghar MI
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- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avetisyan A
- Avila C
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
- Bachtis M
- Baden A
- Baeni L
- Baffioni S
- Bagliesi G
- Bai Y
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Balazs M
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- Barfuss AF
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- Barnes VE
- Barnett BA
- Barney D
- Barone L
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- Bartalini P
- Barth C
- Basegmez S
- Basso L
- Battilana C
- Bauer G
- Bauerdick LAT
- Baumgartel D
- Baur U
- Bayshev I
- Bazterra VE
- Bean A
- Beauceron S
- Beaudette F
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- Beernaert K
- Behr J
- Behrenhoff W
- Behrens U
- Belforte S
- Beliy N
- Belknap D
- Bell AJ
- Bellan R
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- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
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- Zakaria M
- Zalewski P
- Zanetti M
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- Zarubin A
- Zatserklyaniy A
- Zeinali M
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- Zeuner WD
- Zeyrek M
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- Zhukov V
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- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
The azimuthal anisotropy of charged particles in PbPb collisions at
nucleon-nucleon center-of-mass energy of 2.76 TeV is measured with the CMS
detector at the LHC over an extended transverse momentum (pt) range up to
approximately 60 GeV. The data cover both the low-pt region associated with
hydrodynamic flow phenomena and the high-pt region where the anisotropies may
reflect the path-length dependence of parton energy loss in the created medium.
The anisotropy parameter (v2) of the particles is extracted by correlating
charged tracks with respect to the event-plane reconstructed by using the
energy deposited in forward-angle calorimeters. For the six bins of collision
centrality studied, spanning the range of 0-60% most-central events, the
observed v2 values are found to first increase with pt, reaching a maximum
around pt = 3 GeV, and then to gradually decrease to almost zero, with the
decline persisting up to at least pt = 40 GeV over the full centrality range
measured.Comment: Replaced with published version. Added journal reference and DO
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy
- Author
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- Abbiendi G
- Abbrescia M
- Abdullin S
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- Yilmaz Y
- Yohay R
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- Zielinski M
- Zito G
- Zou W
- Zucchetta A
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
A search for new physics is performed in events with two same-sign isolated
leptons, hadronic jets, and missing transverse energy in the final state. The
analysis is based on a data sample corresponding to an integrated luminosity of
4.98 inverse femtobarns produced in pp collisions at a center-of-mass energy of
7 TeV collected by the CMS experiment at the LHC. This constitutes a factor of
140 increase in integrated luminosity over previously published results. The
observed yields agree with the standard model predictions and thus no evidence
for new physics is found. The observations are used to set upper limits on
possible new physics contributions and to constrain supersymmetric models. To
facilitate the interpretation of the data in a broader range of new physics
scenarios, information on the event selection, detector response, and
efficiencies is provided.Comment: Published in Physical Review Letter
Compressed representation of a partially defined integer function over multiple arguments
- Author
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- Abbiendi G
- Abbrescia M
- Abdelalim AA
- Abdullin S
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- Cimmino A
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- Cittolin S
- Ciulli V
- Civinini C
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- Cline D
- CMS Collaboration
- Coarasa Perez JA
- Cockerill DJA
- Colafranceschi S
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- Contardo D
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- Costanza F
- Couderc F
- Coughlan JA
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- Cremaldi LM
- Cripps N
- Cuevas J
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- Cumalat JP
- Cussans D
- Custodio A
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
- D'Alessandro R
- D'Alfonso M
- d'Enterria D
- D'Hondt J
- Da Costa EM
- Dabrowski A
- Daci N
- Dahmes B
- Dahms T
- Dalchenko M
- Dallavalle GM
- Damgov J
- Danielson T
- Das S
- Daskalakis G
- Dasu S
- Daubie E
- Dauncey P
- David A
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- de Barbaro P
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- de Cassagnac RG
- De Cosa A
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- Publication venue
- Publication date
- 01/01/2013
- Field of study
In OLAP (OnLine Analitical Processing) data are analysed in an n-dimensional cube. The cube may be represented as a partially defined function over n arguments. Considering that often the function is not defined everywhere, we ask: is there a known way of representing the function or the points in which it is defined, in a more compact manner than the trivial one
Measurement of jet fragmentation into charged particles in pp and PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
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- Tschudi Y
- Tsirou A
- Tu Y
- Tucker J
- Tully C
- Tumasyan A
- Tuo S
- Tuominen E
- Tuominiemi J
- Tuovinen E
- Tupputi S
- Turkewitz J
- Turner M
- Tuuva T
- Tuve C
- Twedt E
- Tytgat M
- Tyurin N
- Tzeng YM
- Ujvari B
- Ulmer KA
- Ulrich R
- Ungaro D
- Uplegger L
- Urscheler C
- Uvarov L
- Uzunian A
- Vaandering EW
- Valls N
- Valuev V
- Van Doninck W
- Van Haevermaet H
- Van Hove P
- Van Mechelen P
- Van Mulders P
- Van Onsem GP
- Van Remortel N
- Van Spilbeeck A
- Vander Velde C
- Vanelderen L
- Vanini S
- Vanlaer P
- Vardanyan I
- Varela J
- Varelas N
- Vargas JER
- Vartak A
- Vaughan J
- Vavilov S
- Vazquez Valencia F
- Veelken C
- Veeraraghavan V
- Velasco M
- Velicanu D
- Velkovska J
- Venditti R
- Venturi A
- Verdier P
- Verdini PG
- Veres GI
- Vergili LN
- Vergili M
- Verwilligen P
- Verzetti M
- Veszpremi V
- Vesztergombi G
- Veverka J
- Vidal R
- Vila I
- Vilar Cortabitarte R
- Villasenor-Cendejas LM
- Villella I
- Vinogradov A
- Virdee T
- Viret S
- Vischia P
- Vishnevskiy D
- Vitulo P
- Vlasov E
- Vlimant JR
- Vodopiyanov I
- Vogel H
- Volkov A
- Volobouev I
- Volodko A
- Volpe R
- Vorobiev I
- Vorobyev A
- Vorobyev A
- Voutilainen M
- Vuosalo C
- Vutova M
- Wagner P
- Wagner SR
- Wagner-Kuhr J
- Wakefield S
- Wallny R
- Walsh R
- Walsh S
- Waltenberger W
- Walzel G
- Wan X
- Wang J
- Wang J
- Wang M
- Wang S
- Wang X
- Wang Z
- Wardle N
- Wasserbaech S
- Wayand S
- Wayne M
- Weber H
- Weber HA
- Weber M
- Weber M
- Wehrli L
- Weiler T
- Weinberg M
- Wendland L
- Weng Y
- Wenger EA
- Werner JS
- West C
- Wetzel J
- Whitbeck A
- Whitmore J
- Whyntie T
- Wickramage N
- Widl E
- Wilken R
- Wilkinson R
- Williams G
- Williams T
- Willmott C
- Wimpenny S
- Winer BL
- Winn D
- Winstrom L
- Wissing C
- Wittich P
- Wittmer B
- Woehri HK
- Wolf M
- Wolf R
- Womersley WJ
- Won S
- Wood D
- Wood J
- Wood JS
- Worm SD
- Wright D
- Wrochna G
- Wu W
- Wuerthwein F
- Wulz C-E
- Wyslouch B
- Xiao H
- Xie S
- Xu M
- Yagil A
- Yalvac M
- Yang F
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Zielinski M
- Zito G
- Zotto P
- Zou W
- Zucchetta A
- Zumerle G
- Zuranski A
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2012
- Field of study
Jet fragmentation in pp and PbPb collisions at a centre-of-mass energy of
2.76 TeV per nucleon pair was studied using data collected with the CMS
detector at the LHC. Fragmentation functions are constructed using
charged-particle tracks with transverse momenta pt > 4 GeV for dijet events
with a leading jet of pt > 100 GeV. The fragmentation functions in PbPb events
are compared to those in pp data as a function of collision centrality, as well
as dijet-pt imbalance. Special emphasis is placed on the most central PbPb
events including dijets with unbalanced momentum, indicative of energy loss of
the hard scattered parent partons. The fragmentation patterns for both the
leading and subleading jets in PbPb collisions agree with those seen in pp data
at 2.76 TeV. The results provide evidence that, despite the large parton energy
loss observed in PbPb collisions, the partition of the remaining momentum
within the jet cone into high-pt particles is not strongly modified in
comparison to that observed for jets in vacuum.Comment: Submitted to the Journal of High Energy Physic
The counseling african americans to control hypertension (caatch) trial: baseline demographic, clinical, psychosocial, and behavioral characteristics
- Author
- A Schoenthaler
- AI Qureshi
- Andrea Cassells
- AV Chobanian
- Chamanara Kalida
- CL Ogden
- CL Roumie
- D Hedeker
- D Hedeker
- D Perloff
- DE Morisky
- DG Altman
- EH Wagner
- FM Sacks
- G Ogedegbe
- G Ogedegbe
- Gbenga Ogedegbe
- HA Taylor Jr
- HB Bosworth
- HB Bosworth
- HB Bosworth
- JA Cutler
- JE Ware
- JG Ford
- Jonathan N Tobin
- K Kroenke
- KM Gans
- L Corsino
- L Osterberg
- LE Boulware
- LE Fields
- LJ Appel
- LJ Appel
- LJ Appel
- LP Svetkey
- LP Svetkey
- LS Hicks
- M Johns
- MA Albert
- MA McDowell
- Marleny Diaz-Gloster
- MW Johns
- ND Wong
- P Muntner
- Q Gu
- RG Victor
- RJ Dolor
- RS Paffenbarger
- SB Wyatt
- Senaida Fernandez
- T Giles
- T Young
- T Young
- TC Davis
- VK Kapur
- W Gerin
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>Effectiveness of combined physician and patient-level interventions for blood pressure (BP) control in low-income, hypertensive African Americans with multiple co-morbid conditions remains largely untested in community-based primary care practices. Demographic, clinical, psychosocial, and behavioral characteristics of participants in the Counseling African American to Control Hypertension (CAATCH) Trial are described. CAATCH evaluates the effectiveness of a multi-level, multi-component, evidence-based intervention compared with usual care (UC) in improving BP control among poorly controlled hypertensive African Americans who receive primary care in Community Health Centers (CHCs).</p> <p>Methods</p> <p>Participants included 1,039 hypertensive African Americans receiving care in 30 CHCs in the New York Metropolitan area. Baseline data on participant demographic, clinical (<it>e.g</it>., BP, anti-hypertensive medications), psychosocial (<it>e.g</it>., depression, medication adherence, self-efficacy), and behavioral (<it>e.g</it>., exercise, diet) characteristics were gathered through direct observation, chart review, and interview.</p> <p>Results</p> <p>The sample was primarily female (71.6%), middle-aged (mean age = 56.9 ± 12.1 years), high school educated (62.4%), low-income (72.4% reporting less than $20,000/year income), and received Medicaid (35.9%) or Medicare (12.6%). Mean systolic and diastolic BP were 150.7 ± 16.7 mm Hg and 91.0 ± 10.6 mm Hg, respectively. Participants were prescribed an average of 2.5 ± 1.9 antihypertensive medications; 54.8% were on a diuretic; 33.8% were on a beta blocker; 41.9% were on calcium channel blockers; 64.8% were on angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARBs). One-quarter (25.6%) of the sample had resistant hypertension; one-half (55.7%) reported medication non-adherence. Most (79.7%) reported one or more co-morbid medical conditions. The majority of the patients had a Charlson Co-morbidity score ≥ 2. Diabetes mellitus was common (35.8%), and moderate/severe depression was present in 16% of participants. Participants were sedentary (835.3 ± 1,644.2 Kcal burned per week), obese (59.7%), and had poor global physical health, poor eating habits, high health literacy, and good overall mental health.</p> <p>Conclusions</p> <p>A majority of patients in the CAATCH trial exhibited adverse lifestyle behaviors, and had significant medical and psychosocial barriers to adequate BP control. Trial outcomes will shed light on the effectiveness of evidence-based interventions for BP control when implemented in real-world medical settings that serve high numbers of low-income hypertensive African-Americans with multiple co-morbidity and significant barriers to behavior change.</p
Contextual socioeconomic determinants of cardiovascular risk factors in rural south-west China: a multilevel analysis
- Author
- AE Ezeamama
- Alan Geater
- AV Diez-Roux
- B Isomaa
- Cai Le
- CDC
- CH Hennekens
- D Gu
- D Gu
- D Perloff
- Further Study of Risk Factors for stroke and Coronary Heart Disease Cooperation group
- GA Kaplan
- HR Roohafza
- HW Hense
- J Merlo
- JA Walcott-McQuigg
- JL Gutierrez-Fisac
- K Ball
- KM Henriksson
- L Cai
- LS Li
- M Veglio
- MA Winkleby
- P Levy
- P Palatini
- R Development Core Team
- RM Krauss
- RP Wildman
- S Sharma
- SM Saw
- T King
- TAB Snijders
- The expert committee on the diagnosis and classification of diabetes mellitus
- Virasakdi Chongsuvivatwong
- W Hao
- W Hao
- WH Pan
- World Health Organization
- World Health Organization
- X Tang
- XH Fang
- Y Li
- Yunnan Statistical Yearbook
- Publication venue
- BioMed Central
- Publication date
- 01/01/2007
- Field of study
Web-based interventions for weight loss and weight maintenance among rural midlife and older women: protocol for a randomized controlled trial
- Author
- A Khaylis
- A Utter
- B Cardinal
- B Resnick
- CA Befort
- Carol H Pullen
- Centers for Disease Control and Prevention (CDC)
- CF Bove
- CH Pullen
- CH Pullen
- CJ Dye
- CL Himes
- D Moher
- D Perloff
- DA Renjilian
- DB Sarwer
- DF Tate
- DF Tate
- E Calle
- EC Cussler
- J Harvey-Berino
- J Harvey-Berino
- J Harvey-Berino
- JF Sallis
- JF Sallis
- JR Morrow Jr
- JZ Goldfinger
- K Sechrist
- KK Pettee Gabriel
- Linda S Boeckner
- LP Svetkey
- LS Boeckner
- M Csuka
- ME Nelson
- Melody Hertzog
- MM Casey
- MM Yore
- N Pender
- P Diggle
- PA Hageman
- PA Lucey
- Patricia A Hageman
- Q Sun
- R Rikli
- R Vogt
- RC Gershon
- RE Glasgow
- RP Troiano
- RR Wing
- S Fox
- SK Pandey
- SN Walker
- SN Walker
- Susan Noble Walker
- TA Wadden
- TA Wadden
- TM Hale
- TN Robinson
- U.S. Department of Health and Human Services
- U.S. Department of Health and Human Services
- U.S. Department of Health and Human Services
- U.S. Department of Health and Human Services
- U.S. Department of Health and Human Services
- U.S. Department of Health and Human Services and U.S. Department of Agriculture
- U.S. Department of Health and Human Services National Institutes of Health
- VJ Stevens
- WL Haskell
- X Xie
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
Background: Weight loss is challenging and maintenance of weight loss is problematic among midlife and older rural women. Finding effective interventions using innovative delivery methods that can reach underserved and vulnerable populations of overweight and obese rural women is a public health challenge.
Methods/Design: This Women Weigh-In for Wellness (The WWW study) randomized-controlled trial is designed to compare the effectiveness of theory-based behavior-change interventions using (1) website only, (2) website with peer-led support, or (3) website with professional email-counseling to facilitate initial weight loss (baseline to 6 months), guided continuing weight loss and maintenance (7-18 months) and self-directed weight maintenance (19-30 months) among rural women ages 45-69 with a BMI of 28-45. Recruitment efforts using local media will target 306 rural women who live within driving distance of a community college site where assessments will be conducted at baseline, 3, 6, 12, 18, 24 and 30 months by research nurses blinded to group assignments. Primary outcomes include changes in body weight, % weight loss, and eating and activity behavioral and biomarkers from baseline to each subsequent assessment. Secondary outcomes will be percentage of women achieving at least 5% and 10% weight loss without regain from baseline to 6, 18, and 30 months and achieving healthy eating and activity targets. Data analysis will use generalized estimating equations to analyze average change across groups and group differences in proportion of participants achieving target weight loss levels.
Discussion: The Women Weigh-In for Wellness study compares innovative web-based alternatives for providing lifestyle behavior-change interventions for promoting weight loss and weight maintenance among rural women. If effective, such interventions would offer potential for reducing overweight and obesity among a vulnerable, hard-to-reach, population of rural women
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