User Involvement, Procurement Practices and Implementation of Building Construction Projects in the Kenyan Judiciary

Kenyan population increased from 20 million in 1985 to approximately 47.6 million in 2019 and with it, demand for justice also increased yet the growth did not come with improved Judiciary infrastructure. This attracted the World Bank through the Judicial Performance Improvement Project (JPIP) to fund 30 major court construction projects while the Kenyan Government also funded another 33 such projects from 2013. However, by January, 2020,only 10 projects had been completed and successfully handed over with all the 63 projects being out of the planned time and with variation on the original scope of works.This gave rise to this study that aimed to evaluate the influence of user involvement on implementation of building construction projects in the Kenyan judiciary as moderated with the procurement practices. The study was based on general systems theory. Pragmatism paradigm and convergent parallel mixed research design was adopted and proportionate stratified sampling was used to select a population of 234 consisting of judiciary staff, construction staff  and consultants .Primary data was collected through use of questionnaires, interviews and document  content analysis. Reliability was tested using Cronbach’s Alpha while data was analyzed using descriptive statistics which included measures of central tendency. Qualitative data was subjected to thematic analysis to triangulate results derived from quantitative data. Inferential statistics was analyzed by correlation, simple linear regression and multiple regression analysis. Two hypotheses were tested to establish whether there were significant relationships between project delivery attributes and implementation of building construction projects in the Kenyan Judiciary, namely  1.H0:  User Involvement has no significant relationship with implementation of construction projects in the Kenyan Judiciary and 2.H0: There is a significant moderating influence of procurement practices on the relationship between user involvement  and implementation of building construction projects in the Kenyan Judiciary. The findings were that there was a significant influence of user involvement on the implementation of construction projects in the Kenyan Judiciary and that procurement practices significantly moderated the relationship between user involvement and implementation of building construction projects in the Kenyan Judiciary. The slope coefficient was significant when p ≤0.05. The findings of the study will be beneficial to policy makers, project managers in public and private sectors and scholars regarding project delivery attributes on implementation of building construction projects. Keywords: User involvement, Procurement Practices and Implementation of Building Construction Projects. DOI: 10.7176/EJBM/13-18-12 Publication date:September 30th 202

Project Delivery Systems, Procurement Practices and Implementation of Building Construction Projects in the Kenyan Judiciary

Kenyan population increased from 20 million in 1985 to approximately 47.6 million in 2019 and with it, demand for justice also increased yet the growth did not come with improved Judiciary infrastructure. This attracted the World Bank through the Judicial Performance Improvement Project (JPIP) to fund 30 major court construction projects while the Kenyan Government also funded another 33 such projects from 2013. However, by January, 2020,only 10 projects had been completed and successfully handed over with all the 63 projects being out of the planned time and with variation on the original scope of works.This gave rise to this study that aimed to evaluate the influence of project delivery systems on implementation of building construction projects in the Kenyan judiciary as moderated with the procurement practices. The study was based on general systems theory. Pragmatism paradigm and convergent parallel mixed research design was adopted and proportionate stratified sampling was used to select a population of 234 consisting of judiciary staff, construction staff  and consultants.Primary data was collected through use of questionnaires, interviews and document  content analysis. Reliability was tested using Cronbach’s Alpha while data was analyzed using descriptive statistics which included measures of central tendency. Qualitative data was subjected to thematic analysis to triangulate results derived from quantitative data. Inferential statistics was analyzed by correlation, simple linear regression and multiple regression analysis. Two hypotheses were tested to establish whether there were significant relationships between project delivery systems and implementation of building construction projects in the Kenyan Judiciary, namely  1.H0:  Project delivery systems have no significant relationship with implementation of construction projects in the Kenyan Judiciary and 2.H0: There is no significant moderating influence of procurement practices on the relationship between project delivery systems  and implementation of construction projects in the Kenyan Judiciary.The findings were that there was a significant influence of project delivery systems on the implementation of construction projects in the Kenyan Judiciary and that procurement practices significantly moderated the relationship between project delivery systems and implementation of building construction projects in the Kenyan Judiciary.The slope coefficient was significant when p ≤0.05. The findings of the study will be beneficial to policy makers, project managers in public and private sectors and scholars regarding project delivery attributes on implementation of building construction projects. Keywords:Project delivery Systems, Procurement Practices and Implementation of Building Construction Projects. DOI: 10.7176/CER/13-6-03 Publication date:September 30th 202

Artemether-lumefantrine versus artemisinin-naphthoquine in Papua New Guinean children with uncomplicated malaria: A six months post-treatment follow-up study

Background: In a recent trial of artemisinin-naphthoquine (artemisinin-NQ) and artemether-lumefantrine (AM-LM) therapy in young children from Papua New Guinea (PNG), there were no treatment failures in artemisinin-NQ-treated children with Plasmodium falciparum or Plasmodium vivax compared with 2.2% and 30.0%, respectively, in AM-LM-treated children during 42 days of follow-up. To determine whether, consistent with the long elimination half-life of NQ, this difference in efficacy would be more durable, clinical episodes of malaria were assessed in a subset of trial patients followed for six months post-treatment. Methods: For children completing trial procedures and who were assessable at six months, all within-trial and subsequent clinical malaria episodes were ascertained, the latter by clinic attendances and/or review of hand-held health records. Presentations with non-malarial illness were also recorded. Differences between allocated treatments for pre-specified endpoints were determined using Kaplan-Meier survival analysis. Results: Of 247 children who were followed to Day 42, 176 (71.3%) were included in the present sub-study, 87 allocated to AM-LM and 89 to artemisinin-NQ. Twenty children in the AM-LM group (32.8%) had a first episode of clinical malaria within six months compared with 10 (16.4%) in the artemisinin-NQ group (P=0.033, log rank test). The median (interquartile range) time to first episode of clinical malaria was 64 (50-146) vs 116 (77-130) days, respectively (P=0.20). There were no between-group differences in the incidence of first presentation with non-malarial illness (P=0.31). Conclusions: The greater effectiveness of artemisinin-NQ over conventional AM-LM extends to at least six months post-treatment for clinical malaria but not non-malarial illness. Trial registration: Australian New Zealand Clinical Trials Registry ACTRN12610000913077

Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treating Uncomplicated Malaria: A Randomized Trial to Guide Policy in Uganda

BACKGROUND: Uganda recently adopted artemether-lumefantrine (AL) as the recommended first-line treatment for uncomplicated malaria. However, AL has several limitations, including a twice-daily dosing regimen, recommendation for administration with fatty food, and a high risk of reinfection soon after therapy in high transmission areas. Dihydroartemisinin-piperaquine (DP) is a new alternative artemisinin-based combination therapy that is dosed once daily and has a long post-treatment prophylactic effect. We compared the efficacy and safety of AL with DP in Kanungu, an area of moderate malaria transmission. METHODOLOGY/PRINCIPAL FINDINGS: Patients aged 6 months to 10 years with uncomplicated falciparum malaria were randomized to therapy and followed for 42 days. Genotyping was used to distinguish recrudescence from new infection. Of 414 patients enrolled, 408 completed follow-up. Compared to patients treated with artemether-lumefantrine, patients treated with dihydroartemisinin-piperaquine had a significantly lower risk of recurrent parasitaemia (33.2% vs. 12.2%; risk difference = 20.9%, 95% CI 13.0-28.8%) but no statistically significant difference in the risk of treatment failure due to recrudescence (5.8% vs. 2.0%; risk difference = 3.8%, 95% CI -0.2-7.8%). Patients treated with dihydroartemisinin-piperaquine also had a lower risk of developing gametocytaemia after therapy (4.2% vs. 10.6%, p = 0.01). Both drugs were safe and well tolerated. CONCLUSIONS/SIGNIFICANCE: DP is highly efficacious, and operationally preferable to AL because of a less intensive dosing schedule and requirements. Dihydroartemisinin-piperaquine should be considered for a role in the antimalarial treatment policy of Uganda. TRIAL REGISTRATION: Controlled-Trials.com ISRCTN75606663

Current and Historical Drivers of Landscape Genetic Structure Differ in Core and Peripheral Salamander Populations

With predicted decreases in genetic diversity and greater genetic differentiation at range peripheries relative to their cores, it can be difficult to distinguish between the roles of current disturbance versus historic processes in shaping contemporary genetic patterns. To address this problem, we test for differences in historic demography and landscape genetic structure of coastal giant salamanders (Dicamptodon tenebrosus) in two core regions (Washington State, United States) versus the species' northern peripheral region (British Columbia, Canada) where the species is listed as threatened. Coalescent-based demographic simulations were consistent with a pattern of post-glacial range expansion, with both ancestral and current estimates of effective population size being much larger within the core region relative to the periphery. However, contrary to predictions of recent human-induced population decline in the less genetically diverse peripheral region, there was no genetic signature of population size change. Effects of current demographic processes on genetic structure were evident using a resistance-based landscape genetics approach. Among core populations, genetic structure was best explained by length of the growing season and isolation by resistance (i.e. a ‘flat’ landscape), but at the periphery, topography (slope and elevation) had the greatest influence on genetic structure. Although reduced genetic variation at the range periphery of D. tenebrosus appears to be largely the result of biogeographical history rather than recent impacts, our analyses suggest that inherent landscape features act to alter dispersal pathways uniquely in different parts of the species' geographic range, with implications for habitat management

Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate results to policy-relevant administrative and national levels. Additionally, we provide subnational disparity analyses to provide a comprehensive overview of anemia prevalence inequalities within these countries and predict progress toward the World Health Organization’s Global Nutrition Target (WHO GNT) to reduce anemia by half by 2030. Our results demonstrate widespread moderate improvements in overall anemia prevalence but identify only three LMICs with a high probability of achieving the WHO GNT by 2030 at a national scale, and no LMIC is expected to achieve the target in all their subnational administrative units. Our maps show where large within-country disparities occur, as well as areas likely to fall short of the WHO GNT, offering precision public health tools so that adequate resource allocation and subsequent interventions can be targeted to the most vulnerable populations

Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate results to policy-relevant administrative and national levels. Additionally, we provide subnational disparity analyses to provide a comprehensive overview of anemia prevalence inequalities within these countries and predict progress toward the World Health Organization’s Global Nutrition Target (WHO GNT) to reduce anemia by half by 2030. Our results demonstrate widespread moderate improvements in overall anemia prevalence but identify only three LMICs with a high probability of achieving the WHO GNT by 2030 at a national scale, and no LMIC is expected to achieve the target in all their subnational administrative units. Our maps show where large within-country disparities occur, as well as areas likely to fall short of the WHO GNT, offering precision public health tools so that adequate resource allocation and subsequent interventions can be targeted to the most vulnerable populations.Peer reviewe