170 research outputs found
КРІОХІРУРГІЯ ГІПЕРПЛАСТИЧНИХ ЗАХВОРЮВАНЬ ЕНДОМЕТРІЯ
Patients suffering from pretumour diseases of endometrium have complicated somatical and obstetrical anamnesis such as disorders of system of hemostasis, that leads to high risk of thromboembolitic complications (TEC ). Alternative to hormonal and surgical treatment of these patients we consider to be the use of organopreserving endocryosurgical treatment of hyperplastic diseases of endometrium. Effectiveness of (clinical, morphological, ultrasonical), cryosurgical therapy made up 95,9 %; prevention of TEC - 100% cases.Больные, которые страдают предопухолевыми заболеваниями эндометрия имеют отягощенный соматический и акушерско-гинекологический анамнез, нарушения системы гемостаза, что обуславливает повышенный риск тромбоэмболических осложнений (ТЭО). Альтернативой гормональному и хирургическому лечению данных пациенток считаем использование органосохраняющего эндокриохирургического лечения гиперпластических заболеваний эндометрия. Эффективность (клиническая, морфологическая, ультразвуковая) криохирургического лечения составила 95,9%, профилактики ТЭО - 100% случаевХворі, які страждають передпухлинними захворюваннями ендометрія, мають обтяжений соматичний і акушерсько-гінекологічний анамнез, порушення системи гемостазу, що обумовлює підвищений ризиктромбоемболічнихускладнень (ТЕУ). Альтернативою гормональному і хірургічному лікуванню даних пацієнток вважаемо застосування органозберігаючого ендокріохірургічного лікування гіперпластичних захворювань ендометрія. Ефективність (клінічна, морфологічна, ультразвукова) кріохірургічного лікування становила 95,9%, профілактики ТЕУ - 100% випадків
A systematic fitting scheme for caustic-crossing microlensing events
We outline a method for fitting binary-lens caustic-crossing microlensing
events based on the alternative model parameterisation proposed and detailed in
Cassan (2008). As an illustration of our methodology, we present an analysis of
OGLE-2007-BLG-472, a double-peaked Galactic microlensing event with a source
crossing the whole caustic structure in less than three days. In order to
identify all possible models we conduct an extensive search of the parameter
space, followed by a refinement of the parameters with a Markov Chain-Monte
Carlo algorithm. We find a number of low-chi2 regions in the parameter space,
which lead to several distinct competitive best models. We examine the
parameters for each of them, and estimate their physical properties. We find
that our fitting strategy locates several minima that are difficult to find
with other modelling strategies and is therefore a more appropriate method to
fit this type of events.Comment: 12 pages, 11 figure
Limb-darkening measurements for a cool red giant in microlensing event OGLE 2004-BLG-482
Aims: We present a detailed analysis of OGLE 2004-BLG-482, a relatively
high-magnification single-lens microlensing event which exhibits clear
extended-source effects. These events are relatively rare, but they potentially
contain unique information on the stellar atmosphere properties of their source
star, as shown in this study. Methods: Our dense photometric coverage of the
overall light curve and a proper microlensing modelling allow us to derive
measurements of the OGLE 2004-BLG-482 source star's linear limb-darkening
coefficients in three bands, including standard Johnson-Cousins I and R, as
well as in a broad clear filter. In particular, we discuss in detail the
problems of multi-band and multi-site modelling on the expected precision of
our results. We also obtained high-resolution UVES spectra as part of a ToO
programme at ESO VLT from which we derive the source star's precise fundamental
parameters. Results: From the high-resolution UVES spectra, we find that OGLE
2004-BLG-482's source star is a red giant of MK type a bit later than M3, with
Teff = 3667 +/- 150 K, log g = 2.1 +/- 1.0 and an assumed solar metallicity.
This is confirmed by an OGLE calibrated colour-magnitude diagram. We then
obtain from a detailed microlensing modelling of the light curve linear
limb-darkening coefficients that we compare to model-atmosphere predictions
available in the literature, and find a very good agreement for the I and R
bands. In addition, we perform a similar analysis using an alternative
description of limb darkening based on a principal component analysis of ATLAS
limb-darkening profiles, and also find a very good agreement between
measurements and model predictions.Comment: Accepted in A&
Extreme Magnification Microlensing Event OGLE-2008-BLG-279: Strong Limits on Planetary Companions to the Lens Star
We analyze the extreme high-magnification microlensing event
OGLE-2008-BLG-279, which peaked at a maximum magnification of A ~ 1600 on 30
May 2008. The peak of this event exhibits both finite-source effects and
terrestrial parallax, from which we determine the mass of the lens, M_l=0.64
+/- 0.10 M_Sun, and its distance, D_l = 4.0 +/- 0.6. We rule out Jupiter-mass
planetary companions to the lens star for projected separations in the range
0.5-20 AU. More generally, we find that this event was sensitive to planets
with masses as small as 0.2 M_Earth ~= 2 M_Mars with projected separations near
the Einstein ring (~3 AU).Comment: 25 pages, 7 figures, submitted to Ap
Interpretation of Strong Short-Term Central Perturbations in the Light Curves of Moderate-Magnification Microlensing Events
To improve the planet detection efficiency, current planetary microlensing
experiments are focused on high-magnification events searching for planetary
signals near the peak of lensing light curves. However, it is known that
central perturbations can also be produced by binary companions and thus it is
important to distinguish planetary signals from those induced by binary
companions. In this paper, we analyze the light curves of microlensing events
OGLE-2007-BLG-137/MOA-2007-BLG-091, OGLE-2007-BLG-355/MOA-2007-BLG-278, and
MOA-2007-BLG-199/OGLE-2007-BLG-419, for all of which exhibit short-term
perturbations near the peaks of the light curves. From detailed modeling of the
light curves, we find that the perturbations of the events are caused by binary
companions rather than planets. From close examination of the light curves
combined with the underlying physical geometry of the lens system obtained from
modeling, we find that the short time-scale caustic-crossing feature occurring
at a low or a moderate base magnification with an additional secondary
perturbation is a typical feature of binary-lens events and thus can be used
for the discrimination between the binary and planetary interpretations.Comment: 17 pages, 4 figures, 1 tabl
Characterizing Low-Mass Binaries From Observation of Long Time-scale Caustic-crossing Gravitational Microlensing Events
Despite astrophysical importance of binary star systems, detections are
limited to those located in small ranges of separations, distances, and masses
and thus it is necessary to use a variety of observational techniques for a
complete view of stellar multiplicity across a broad range of physical
parameters. In this paper, we report the detections and measurements of 2
binaries discovered from observations of microlensing events MOA-2011-BLG-090
and OGLE-2011-BLG-0417. Determinations of the binary masses are possible by
simultaneously measuring the Einstein radius and the lens parallax. The
measured masses of the binary components are 0.43 and 0.39
for MOA-2011-BLG-090 and 0.57 and 0.17 for
OGLE-2011-BLG-0417 and thus both lens components of MOA-2011-BLG-090 and one
component of OGLE-2011-BLG-0417 are M dwarfs, demonstrating the usefulness of
microlensing in detecting binaries composed of low-mass components. From
modeling of the light curves considering full Keplerian motion of the lens, we
also measure the orbital parameters of the binaries. The blended light of
OGLE-2011-BLG-0417 comes very likely from the lens itself, making it possible
to check the microlensing orbital solution by follow-up radial-velocity
observation. For both events, the caustic-crossing parts of the light curves,
which are critical for determining the physical lens parameters, were resolved
by high-cadence survey observations and thus it is expected that the number of
microlensing binaries with measured physical parameters will increase in the
future.Comment: 8 pages, 5 figures, 4 table
Frequency of Solar-Like Systems and of Ice and Gas Giants Beyond the Snow Line from High-Magnification Microlensing Events in 2005-2008
We present the first measurement of planet frequency beyond the "snow line"
for planet/star mass-ratios[-4.5<log q<-2]: d^2 N/dlog q/dlog
s=(0.36+-0.15)/dex^2 at mean mass ratio q=5e-4, and consistent with being flat
in log projected separation, s. Our result is based on a sample of 6 planets
detected from intensive follow-up of high-mag (A>200) microlensing events
during 2005-8. The sample host stars have typical mass M_host 0.5 Msun, and
detection is sensitive to planets over a range of projected separations
(R_E/s_max,R_E*s_max), where R_E 3.5 AU sqrt(M_host/Msun) is the Einstein
radius and s_max (q/5e-5)^{2/3}, corresponding to deprojected separations ~3
times the "snow line". Though frenetic, the observations constitute a
"controlled experiment", which permits measurement of absolute planet
frequency. High-mag events are rare, but the high-mag channel is efficient:
half of high-mag events were successfully monitored and half of these yielded
planet detections. The planet frequency derived from microlensing is a factor 7
larger than from RV studies at factor ~25 smaller separations [2<P<2000 days].
However, this difference is basically consistent with the gradient derived from
RV studies (when extrapolated well beyond the separations from which it is
measured). This suggests a universal separation distribution across 2 dex in
semi-major axis, 2 dex in mass ratio, and 0.3 dex in host mass. Finally, if all
planetary systems were "analogs" of the Solar System, our sample would have
yielded 18.2 planets (11.4 "Jupiters", 6.4 "Saturns", 0.3 "Uranuses", 0.2
"Neptunes") including 6.1 systems with 2 or more planet detections. This
compares to 6 planets including one 2-planet system in the actual sample,
implying a first estimate of 1/6 for the frequency of solar-like systems.Comment: 42 pages, 10 figure
MOA-2009-BLG-387Lb: A massive planet orbiting an M dwarf
We report the discovery of a planet with a high planet-to-star mass ratio in
the microlensing event MOA-2009-BLG-387, which exhibited pronounced deviations
over a 12-day interval, one of the longest for any planetary event. The host is
an M dwarf, with a mass in the range 0.07 M_sun < M_host < 0.49M_sun at 90%
confidence. The planet-star mass ratio q = 0.0132 +- 0.003 has been measured
extremely well, so at the best-estimated host mass, the planet mass is m_p =
2.6 Jupiter masses for the median host mass, M = 0.19 M_sun. The host mass is
determined from two "higher order" microlensing parameters. One of these, the
angular Einstein radius \theta_E = 0.31 +- 0.03 mas, is very well measured, but
the other (the microlens parallax \pi_E, which is due to the Earth's orbital
motion) is highly degenate with the orbital motion of the planet. We
statistically resolve the degeneracy between Earth and planet orbital effects
by imposing priors from a Galactic model that specifies the positions and
velocities of lenses and sources and a Kepler model of orbits. The 90%
confidence intervals for the distance, semi-major axis, and period of the
planet are 3.5 kpc < D_L < 7.9 kpc, 1.1 AU < a < 2.7AU, and 3.8 yr < P < 7.6
yr, respectively.Comment: 20 pages including 8 figures. A&A 529 102 (2011
Jervell and Lange-Nielsen Syndrome: Novel Compound Heterozygous Mutations in the KCNQ1 in a Korean Family
The Jervell and Lange-Nielsen syndrome (JLNS) is an autosomal recessive syndrome characterized by congenital deafness and cardiac phenotype (QT prolongation, ventricular arrhythmias, and sudden death). JLNS has been shown to occur due to homozygous mutation in KCNQ1 or KCNE1. There have been a few clinical case reports on JLNS in Korea; however, these were not confirmed by a genetic study. We identified compound heterozygous mutations in KCNQ1 in a 5-yr-old child with JLNS, who visited the hospital due to recurrent syncope and seizures and had congenital sensorineural deafness. His electrocardiogram revealed a markedly prolonged corrected QT interval with T wave alternans. The sequence analysis of the proband revealed the presence of novel compound heterozygous deletion/splicing error mutations (c.828-830 delCTC, p.S277del/c.921G>A, p.V307V). Each mutation in KCNQ1 was identified on the maternal and paternal side. With β-blocker therapy the patient has remained symptom-free for three and a half years
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