Influência dos Social Media no Comportamento Alimentar, Atividade Física e Satisfação Corporal em jovens adultos

Introdução: A sociedade moderna ocidental é seriamente influenciada pelos Social Media, sendo os adolescentes e jovens adultos os grupos populacionais com uma maior probabilidade de desenvolverem comportamentos de risco, no que respeita à alimentação e exercício físico.Objetivo: Avaliar a influência dos Social Media no comportamento alimentar, atividade física e satisfação corporal em jovens adultos.Materiais e métodos: Foram recolhidos dados de 100 indivíduos (56 mulheres e 44 homens, sócios de três ginásios do distrito de Aveiro, com idades compreendidas entre 18-30 anos.Um questionário sociodemográfico, o Eating Attitudes Test -26 (EAT26); o International Physical Activity Questionnaire (IPAQ), o Behavioural Regulation in Exercise Questionaire-3 (BREQ3), Countour Drawing Rating Scale (CDRS), Sociocultural Attitudes Questionnaire in Relation to Appearance - 3(SATAQ3) e a Escala de Autoestima de Estado de Heatherton e Polivy foram aplicados.Foram recolhidos dados antropométricos (peso e altura) e o Índice de Massa Corporal (IMC) foi calculado.Resultados: Apesar do IMC da amostra ser 24,6±4,1kg/m2, 80% encontrava-se insatisfeito com a sua imagem corporal. A amostra apresentava comportamentos alimentares de risco. As mulheres praticam mais exercício físico, mas obtiveram pontuações mais altas nas escalas de Motivação Controlada e Amotivação do BREQ3, havendo diferenças significativas entre os sexos na Amotivação (p=0,01). Verificou-se uma associação positiva entre a motivação para a prática de AF e a subescala ideal de corpo (B=1,01; IC 95%: 0,32; 1,71; p=0,01). Após ajuste para o sexo e IMC, registou-se associação negativa entre a motivação para a prática de AF e a subescala Social Media como fonte de informação sobre a aparência (B=-0,76; IC 95%: (-1,38;-0,15); p=0,02). Não se verificaram associações significativas entre as Atitudes Socioculturais em Relação à Aparência e suas subescalas e a AF e a autoestima.Conclusão: Os Social Media têm uma influência significativa no comportamento alimentar e na atividade física da amostra, existindo ainda uma relação inversa entre os Media e a satisfação corporal.Introduction: Western modern society is heavily influenced by social media, with adolescents and young adults being the population groups most likely to develop risky behaviors with regard to diet and exercise.Objective: To evaluate the influence of Social Media on eating behavior, physical activity and body satisfaction in young adults.Materials and methods: Data were collected from 100 individuals (56 women and 44 men, members of three gyms in the district of Aveiro, aged 18-30 years. A sociodemographic questionnaire, the Eating Attitudes Test -26 (EAT26); The International Physical Activity Questionnaire (IPAQ), the Behavioral Regulation in Exercise Questionnaire-3 (BREQ3), the Countour Drawing Rating Scale (CDRS), the Heatherton State Self-Esteem Scale and the Sociocultural Attitudes Questionnaire in Relation to Appearance Polivy were applied. Anthropometric data (weight and height) were collected and the Body Mass Index (BMI) was calculated.Results: Although the BMI of the sample was 24.6 ± 4.1 kg / m2, 80% were dissatisfied with their body image. The sample presented risky dietary behaviors. Women exercised more exercise, but obtained higher scores on the Controlled Motivation and Amotivation scales of BREQ3, with significant differences between the sexes in the Amotivation (p = 0.01). There was a positive association between the motivation for the practice of PA and the ideal body subscale (B = 1.01, 95% IC: 0.32, 1.71, p = 0.01). After adjusting for sex and BMI, there was a negative association between the motivation for the practice of PA and the subscale Social Media as a source of information about the appearance (B = -0.76, 95% IC: -1.38 ; -0.15), p = 0.02). There were no significant associations between Sociocultural Attitudes regarding Appearance and its subscales and FA and self-esteem.Conclusion: Social Media has a significant influence on the food behavior and physical activity of the sample, and there is an inverse relationship between the media and body satisfactio

Achados histopatológicos de atividade inflamatória em pacientes com cardite subclínica

Nos pacientes com Cardite Reumática Crônica, a cardite em atividade é uma condição frequentemente subdiagnosticada. Os surtos reumáticos promovem o agravamento das lesões já existentes, levando a uma deterioração da condição clínica do paciente. Dessa forma a redução da morbimortalidade da doença depende, em parte, do controle de recidivas a partir da profilaxia secundária. O subdiagnóstico deve-se em parte a ocorrência de surtos reumáticos subclínicos. Este estudo foi realizado com dados dos pacientes que tiveram o diagnóstico de Cardite Reumática Crônica e foram submetidos à cirurgia cardíaca para troca ou plastia valvar, sem evidência clínica ou laboratorial desurto reumático. Um fragmento de miocárdio foi enviado para análise histopatológica. Foram analisados os dados de frequência de alterações histopatológicas compatíveis com surto reumático. Após análises, 80% dos pacientes apresentaram alterações compatíveis com atividade inflamatória. Desses, 87,5% apresentavam infiltrado linfocitário;25% apresentavam nódulos de Aschoff. Os achados histopatológicos de doença crônica mais frequentes foram hipertrofia miocárdica em 56,7% pacientes e fibrose em 53,3%.In patients with Chronic Rheumatic Carditis, active carditis is an often underdiagnosed condition. Rheumatic attacks promote the aggravation of existing lesions, leading to a deterioration of the patient’s clinical condition. Thus, reducing the morbidity and mortality of the disease depends, in part, on controlling relapses through secondary prophylaxis. Underdiagnosis is due in part to the occurrence of subclinical rheumatic attacks. This study was carried out with data from patients who were diagnosed with Chronic Rheumatic Carditis and who underwent cardiac surgery for valve replacement or repair, without clinical or laboratory evidence of rheumatic outbreak. A fragment of myocardium was sent for histopathological analysis. Data on the frequency of histopathological alterations compatible with a rheumatic outbreak were analyzed. After analysis, 80% of patients showed changes compatible with inflammatory activity. Of these, 87.5% had lymphocytic infiltrate; 25% had Aschoff’s nodules. The most frequent histopathological findings of chronic disease were myocardial hypertrophy in 56.7% of patients and fibrosis in 53.3%

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Dinâmicas de (investig)ação em contextos de promoção da língua portuguesa: a presença do CIDTFF na rede Camões, I.P.

Sem resumo disponível.publishe

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

Salivary neoplasias with myoepithelial differentiation : immunoexpression study of the CD10 (CALLA/NEP 24.11) and podoplanin (D2-40)

Orientador: Albina Messias de Almeida Milani AltemaniTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias MedicasResumo: CD10 e Podoplanina (D2-40), além de expressos nas células mioepiteliais, estão envolvidos na progressão tumoral e podem ser utilizados como marcadores prognósticos. Em 79 neoplasias salivares com diferenciação mioepitelial (44 malignas e 35 benignas), analisamos a expressão dessas proteínas nas células neoplásicas, na reação desmoplásica tumoral e, nos carcinomas adenóides císticos (CAC), verificamos possível correlação com fatores prognósticos. CD10 foi negativo nas células epiteliais em 100% dos casos. Nas mioepiteliais, foi positivo em 25,71% das lesões benignas e em 27,27% das malignas, sendo esses resultados significantemente inferiores àqueles da a-SMA (60% e 88,64%, respectivamente). CD10 foi positivo em 83,33%, 30%, 27,7% e 40% dos carcinomas epiteliais-mioepiteliais (CEME), adenomas pleomórficos, mioepiteliomas e carcinomas mioepiteliais, respectivamente, e negativo em 100% dos CAC, adenocarcinomas polimórficos de baixo grau (APBG) e adenomas de células basais. No estroma tumoral, a expressão do CD10 (38,64%) foi significantemente maior (p=0.007) que a da a-SMA (11,36%). Entretanto, a expressão do CD10 não apresentou correlação com os fatores prognósticos do CAC. O D2-40 foi negativo, nas células epiteliais e estromais, e positivo nas mioepiteliais em 59% dos carcinomas e em 42,86% das lesões benignas. Concluímos que, ao contrário do D2-40, o CD10 tem pouca utilidade para identificar células mioepiteliais malignas, exceto no CEME onde pode ser útil no diagnóstico diferencial com a variante tubular do CAC. Sua expressão estromal ocorre em células de fenótipo distinto dos miofibroblastos, está associada com invasão tumoral e não se correlaciona com fatores prognósticos do CAC.AbstrAct: CD10 and Podoplanin (D2-40) are expressed in myoepithelial cells and, in addition, are involved in tumoral progression and can be utilized as prognostic markers. In a series of 79 salivary neoplasias with myoepithelial differentiation (44 malignant and 35 benign), the expression of these proteins was analyzed in tumor cells as well as in tumor-associated stromal cells and it was correlated with prognostic factors in a select group of lesions (adenoid cystic carcinomas). In epithelial cells, CD10 was negative in 100% of the cases. In myoepithelial cells, CD10 was positive in 25.71% of the benign neoplasias and in 27.27% of the malignant ones and this expressions was significantly lower in comparison to that of a-smooth muscle actin (a-SMA) (60% and 88.64%, respectively). In neoplasias classified according to histological subtype, CD10 was positive in 83.33%, 30%, 27.27% and 40% of epithelial-myoepithelial carcinomas (EMC), pleomorphic adenomas, myoepitheliomas and myoepithelial carcinomas, respectively and negative in 100% of adenoid cystic carcinomas (ACC), polymorphic low-grade adenocarcinomas (PLGA) and basal adenomas. In tumor-associated stromal cells, CD10 expression was significantly higher (p=0.007) than that of a-SMA (38.64% versus 11.36%). However, no correlation was detected between CD10 expression and prognostic factors in ACC. D2-40 was negative in epithelial cells and in tumorassociated stromal cells as well and positive in myoepithelial cells of carcinomas (59%) and benign lesions (42.86%). This reactivity in myoepithelial cells did not differ significantly of that using a-SMA as a marker, except for PLGA where D2-40 was negative. In conclusion, CD10 differs of D2-40 once it shows low utility to detect neoplastic myoepithelial cells. However, EMC is an exception and in this tumor, CD10 could be useful to separate this lesion from tubular variant of ACC. In the tumor-associated stroma, CD10 expression in non-myofibroblast cells seems to be associated with tumor invasion but it does not show correlation with prognostic factors in ACC.DoutoradoAnatomia PatologicaDoutor em Ciências Médica