Forty years of carabid beetle research in Europe - from taxonomy, biology, ecology and population studies to bioindication, habitat assessment and conservation

Volume: 100Start Page: 55End Page: 14

Checklist of the clown beetles (Coleoptera, Histeridae) from the Republic of Moldova

The fauna of Histeridae (Coleoptera) from the Republic of Moldova is summarized. During the study period, more than 600 individuals were identified, totaling in 68 species belonging to 23 genera, 8 tribes and 6 subfamilies. The Histeridae from the Republic of Moldova currently contain the follow- ing subfamilies, with genera and species count: Abraeinae W. S. Macleay, 1819 (3 species, 3 genera), Dendrophilinae Reitter, 1909 (5 species, 4 genera), Haeteriinae Marseul, 1857 (1 species, 1 genus), Histerinae Gyllenhal, 1808 (30 species, 8 genera), Onthophilinae W. S. Macleay, 1819 (1 species, 1 genus), Saprininae C. É. Blanchard, 1845 (28 species, 6 genera). Pachylister inaequalis (Olivier, 1789), Saprinus maculatus (P. Rossi, 1792) and Margarinotus marginatus (Erichson, 1834) are reported as new taxa to the fauna of the Republic of Moldova. The checklist of the Histeridae of Republic of Moldova is given

Successful Use of Intravenous Immunoglobulin G to Treat Refractory Heparin-Induced Thrombocytopenia With Thrombosis Complicating Peripheral Blood Stem Cell Harvest

Heparin-induced thrombocytopenia is a well-known, life-threatening complication that occurs in 5% of patients exposed to heparin. It causes thrombocytopenia in roughly 85% to 90% of affected individuals, with expected recovery in approximately 4 to 10 days following heparin withdrawal. However, there is an entity known as refractory heparin-induced thrombocytopenia with thrombosis in which patients have prolonged thrombocytopenia, refractory to the current standard of care. We present one such case of a 48-year-old male with R-ISS (Revised International Staging System) stage II kappa light chain multiple myeloma in stringent complete response status postinduction therapy. He developed heparin-induced thrombocytopenia with thrombosis during peripheral blood stem cell harvesting, manifesting as acute right coronary artery thrombus and severe thrombocytopenia. Although his clinical course was prolonged, he was ultimately successfully treated with intravenous immunoglobulin G 500 mg/kg/day over 4 days

Findings of Multiple Myeloma in Afro-Caribbean Patients in the United States

Background: Multiple myeloma (MM) is the second most common malignancy in the United States and has a higher incidence in the black and Afro-Caribbean population. There remain limited data on disease presentation and clinical characteristics in this patient group in the United States. The clinical profile of MM in this underrepresented patient group is described here. Methods: This retrospective study was conducted at Kings County Hospital, an urban New York City hospital in a majority Afro-Caribbean neighborhood. Data from patients diagnosed with MM from 2000 through 2013 were collected from the institution’s tumor registry. Clinical and demographic characteristics of these patients were then analyzed. Results: Patients with a diagnosis of MM were identified (N = 287). Data were available for 231 patients and of these, 97% self-identified as black. 55% were female, and there was a male-to-female ratio of 1:1.2. The mean age of female patients was 64 years; that of male patients was 63 years. Of the 231 patients, 81% had anemia, 68% had bone lesions, 47% had renal impairment, and 29% had hypercalcemia. Low levels of monoclonal protein were present in 27% of patients and 57% had disease of International Staging System stages I and II. Women had higher BMI than men. Conclusion: The mean age of presentation of MM in Afro-Caribbean patients is similar to that in the standard population; however, unlike the general US population, there was a higher incidence in women; mean BMI of women also was higher than that of male patients. A sizeable percentage of Afro-Caribbean patients with MM presented with low levels of monoclonal protein in the presence of multiorgan involvement and damage, suggesting the need for early and aggressive diagnostic testing