Pengaruh Intellectual Capital Terhadap Abnormal Return Saham Dan Kinerja Keuangan (Studi Pada Perusahaan Perbankan Di Bursa Efek Indonesia Tahun 2011-2015)

The purpose of this study was to examine the effect of intellectual capital to abnormal stock return and financial perfomance of banking firms. The abnormal stock return was measured by cumulative abnormal return (CAR), and average abnormal return (AAR), the company\u27s financial perfomance measured by return on assets (ROA), assets turn over (ATO) and growth in revenue (GR). Laten variables used in this study was the perfomance of intellectual capital as measured by VAIC™ (VACA, VAHU, STVA). The sample study was using banking company listed in Indonesia Stock Exchange (IDX) for 2011-2015. Research data using purposive sampling method. Data obtained amounted to 75 companies in the period 2011-2015. This study uses PLS version 3.0 to analyze the data. The result showed that significant intellectual capital positive significantly effect the abnormal stock return and financial perfomance that measured by CAR, AAR, ROA and ATO, but no effect on GR. Overall, this research found that structural capital (STVA) gives the most contribution in creating value added of the company

Isolated calcaneal tuberculous osteomyelitis in a 13-year female: a diagnostic dilemma: rare case report and review of literature

Foot and ankle involvement in osteoarticular tuberculosis is uncommon and isolated calcaneal tubercular osteomyelitis of foot bones sparing nearby joints with an osteolytic defect is even more rare. Worsening of the disease can occur over a time involving nearby joints and small bones if diagnostic and therapeutic phase are delayed. We present a retrospective study of osteolytic variety of foot calcaneal bone tuberculosis. We present a case report of 13-year female with isolated osteolytic variety of calcaneal tuberculous osteomyelitis to highlight the clinical, radiological features and management challenges of the condition. Biopsy was done to confirm tissue diagnosis based on Gene Xpert, AFB staining, MGIT culture, and histopathology. Surgical intervention was done in form of debridement and sinus tract removal as a diagnostic and therapeutic purpose to prevent further involvement of a nearby joints and small bone with cystic destruction. Isolated calcaneal tubercular osteomyelitis cases are still found to be seen in our environment though considered a rare. When tuberculous pathology is limited to the isolated calcaneal bone sparing the other joints, the prognosis is better than in osteoarticular disease, as there is less deformity, and hence, less residual pain and disability

Matter wave pulses characteristics

We study the properties of quantum single-particle wave pulses created by sharp-edged or apodized shutters with single or periodic openings. In particular, we examine the visibility of diffraction fringes depending on evolution time and temperature; the purity of the state depending on the opening-time window; the accuracy of a simplified description which uses ``source'' boundary conditions instead of solving an initial value problem; and the effects of apodization on the energy width.Comment: 11 pages, 11 figure

Effect of Wood-derived Charcoal Content on Properties of Wood Plastic Composites

The effect of wood-derived charcoal flour on the water resistance and mechanical properties of wood plastic composite (WPC) panels was investigated. The hot press molded WPC panels were produced from polypropylene (37 wt%) with maleic anhydride-grafted polypropylene (MAPP, 3 wt%) and different mixtures of wood flour and charcoal flour. The amount of charcoal flour was gradually increased up to 60 wt%. The thickness swelling and water absorption of WPC panels considerably decreased with increasing charcoal flour content. The internal bond strength and bending properties of the WPC panels significantly improved with increasing charcoal flour content. This was mainly attributed to the high amount of pores and gaps in the charcoal flour. Melted polypropylene could get into the pores and gaps during the hot press molding, which lead to a better interfacial adhesion between polymer matrix and wood filler. The results showed that the charcoal flour could be partially substituted for the wood flour in the production of WPC panels having higher dimensional stability and internal bond strength

FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma

The oncogene FOXM1 has been implicated in all major types of human cancer. We recently showed that aberrant FOXM1 expression causes stem cell compartment expansion resulting in the initiation of hyperplasia. We have previously shown that FOXM1 regulates HELLS, a SNF2/helicase involved in DNA methylation, implicating FOXM1 in epigenetic regulation. Here, we have demonstrated using primary normal human oral keratinocytes (NOK) that upregulation of FOXM1 suppressed the tumour suppressor gene p16INK4A (CDKN2A) through promoter hypermethylation. Knockdown of HELLS using siRNA re-activated the mRNA expression of p16INK4A and concomitant downregulation of two DNA methyltransferases DNMT1 and DNMT3B. The dose-dependent upregulation of endogenous FOXM1 (isoform B) expression during tumour progression across a panel of normal primary NOK strains (n = 8), dysplasias (n = 5) and head and neck squamous cell carcinoma (HNSCC) cell lines (n = 11) correlated positively with endogenous expressions of HELLS, BMI1, DNMT1 and DNMT3B and negatively with p16INK4A and involucrin. Bisulfite modification and methylation-specific promoter analysis using absolute quantitative PCR (MS-qPCR) showed that upregulation of FOXM1 significantly induced p16INK4A promoter hypermethylation (10-fold, P<0.05) in primary NOK cells. Using a non-bias genome-wide promoter methylation microarray profiling method, we revealed that aberrant FOXM1 expression in primary NOK induced a global hypomethylation pattern similar to that found in an HNSCC (SCC15) cell line. Following validation experiments using absolute qPCR, we have identified a set of differentially methylated genes, found to be inversely correlated with in vivo mRNA expression levels of clinical HNSCC tumour biopsy samples. This study provided the first evidence, using primary normal human cells and tumour tissues, that aberrant upregulation of FOXM1 orchestrated a DNA methylation signature that mimics the cancer methylome landscape, from which we have identified a unique FOXM1-induced epigenetic signature which may have clinical translational potentials as biomarkers for early cancer screening, diagnostic and/or therapeutic interventions

Comparative Phylogeography in a Specific and Obligate Pollination Antagonism

In specific and obligate interactions the nature and abundance of a given species can have important effects on the survival and population dynamics of associated organisms. In a phylogeographic framework, we therefore expect that the fates of organisms interacting specifically are also tightly interrelated. Here we investigate such a scenario by analyzing the genetic structures of species interacting in an obligate plant-insect pollination lure-and-trap antagonism, involving Arum maculatum (Araceae) and its specific psychodid (Diptera) visitors Psychoda phalaenoides and Psycha grisescens. Because the interaction is asymmetric (i.e., only the plant depends on the insect), we expect the genetic structure of the plant to be related with the historical pollinator availability, yielding incongruent phylogeographic patterns between the interacting organisms

Apoptosis of Purified CD4+ T Cell Subsets Is Dominated by Cytokine Deprivation and Absence of Other Cells in New Onset Diabetic NOD Mice

BACKGROUND: Regulatory T cells (Treg) play a significant role in immune homeostasis and self-tolerance. Excessive sensitivity of isolated Treg to apoptosis has been demonstrated in NOD mice and humans suffering of type 1 diabetes, suggesting a possible role in the immune dysfunction that underlies autoimmune insulitis. In this study the sensitivity to apoptosis was measured in T cells from new onset diabetic NOD females, comparing purified subsets to mixed cultures. PRINCIPAL FINDINGS: Apoptotic cells are short lived in vivo and death occurs primarily during isolation, manipulation and culture. Excessive susceptibility of CD25(+) T cells to spontaneous apoptosis is characteristic of isolated subsets, however disappears when death is measured in mixed splenocyte cultures. In variance, CD25(-) T cells display balanced sensitivity to apoptosis under both conditions. The isolation procedure removes soluble factors, IL-2 playing a significant role in sustaining Treg viability. In addition, pro- and anti-apoptotic signals are transduced by cell-to-cell interactions: CD3 and CD28 protect CD25(+) T cells from apoptosis, and in parallel sensitize naïve effector cells to apoptosis. Treg viability is modulated both by other T cells and other subsets within mixed splenocyte cultures. Variations in sensitivity to apoptosis are often hindered by fast proliferation of viable cells, therefore cycling rates are mandatory to adequate interpretation of cell death assays. CONCLUSIONS: The sensitivity of purified Treg to apoptosis is dominated by cytokine deprivation and absence of cell-to-cell interactions, and deviate significantly from measurements in mixed populations. Balanced sensitivity of naïve/effector and regulatory T cells to apoptosis in NOD mice argues against the concept that differential susceptibility affects disease evolution and progression

Optimal Model for Path Loss Predictions using Feed-Forward Neural Networks

[EN] In this paper, an optimal model is developed for path loss predictions using the Feed-Forward Neural Network (FFNN) algorithm. Drive test measurements were carried out in Canaanland Ota, Nigeria and Ilorin, Nigeria to obtain path loss data at varying distances from 11 different 1,800 MHz base station transmitters. Single-layered FFNNs were trained with normalized terrain profile data (longitude, latitude, elevation, altitude, clutter height) and normalized distances to produce the corresponding path loss values based on the Levenberg-Marquardt algorithm. The number of neurons in the hidden layer was varied (1-50) to determine the Artificial Neural Network (ANN) model with the best prediction accuracy. The performance of the ANN models was evaluated based on different metrics: Mean Absolute error (MAE), Mean Squared Error (MSE), Root Mean Squared Error (RMSE), standard deviation, and regression coefficient (R). Results of the machine learning processes show that the FNN architecture adopting a tangent activation function and 48 hidden neurons produced the least prediction error, with MAE, MSE, RMSE, standard deviation, and R values of 4.21 dB, 30.99 dB, 5.56 dB, 5.56 dB, and 0.89, respectively. Regarding generalization ability, the predictions of the optimal ANN model yielded MAE, MSE, RMSE, standard deviation, and R values of 4.74 dB, 39.38 dB, 6.27 dB, 6.27 dB, and 0.86, respectively, when tested with new data not previously included in the training process. Compared to the Hata, COST 231, ECC-33, and Egli models, the developed ANN model performed better in terms of prediction accuracy and generalization ability.This work was supported by Covenant University [grant number CUCRID-SMARTCU-000343].Popoola, SI.; Adetiba, E.; Atayero, AA.; Faruk, N.; Tavares De Araujo Cesariny Calafate, CM. (2018). Optimal Model for Path Loss Predictions using Feed-Forward Neural Networks. Cogent Engineering. 5:1-19. https://doi.org/10.1080/23311916.2018.1444345S1195Adetiba, E., Iweanya, V. C., Popoola, S. I., Adetiba, J. N., & Menon, C. (2017). Automated detection of heart defects in athletes based on electrocardiography and artificial neural network. Cogent Engineering, 4(1). doi:10.1080/23311916.2017.1411220Adetiba, E., & Olugbara, O. O. (2015). Lung Cancer Prediction Using Neural Network Ensemble with Histogram of Oriented Gradient Genomic Features. The Scientific World Journal, 2015, 1-17. doi:10.1155/2015/786013Adeyemo, Z. K., Ogunremi, O. K., & Ojedokun, I. A. (2016). Optimization of Okumura-Hata Model for Long Term Evolution Network Deployment in Lagos, Nigeria. International Journal on Communications Antenna and Propagation (IRECAP), 6(3), 146. doi:10.15866/irecap.v6i3.9012Akhoondzadeh-Asl, L., & Noori, N. (2007). Modification and Tuning of the Universal Okumura-Hata Model for Radio Wave Propagation Predictions. 2007 Asia-Pacific Microwave Conference. doi:10.1109/apmc.2007.4554925Al Salameh, M. S., & Al-Zu’bi, M. M. (2015). Prediction of radiowave propagation for wireless cellular networks in Jordan.Paper presented at the Knowledge and Smart Technology (KST), 2015 7th International Conference on.Alamoud, M. A., & Schutz, W. (2012). Okumura-hata model tuning for TETRA mobile radio networks in Saudi Arabia. 2012 2nd International Conference on Advances in Computational Tools for Engineering Applications (ACTEA). doi:10.1109/ictea.2012.6462901Armenta, A., Serrano, A., Cabrera, M., & Conte, R. (2011). The new digital divide: the confluence of broadband penetration, sustainable development, technology adoption and community participation. Information Technology for Development, 18(4), 345-353. doi:10.1080/02681102.2011.625925Begovic, P., Behlilovic, N., & Avdic, E. (2012). Applicability evaluation of Okumura, Ericsson 9999 and winner propagation models for coverage planning in 3.5 GHZ WiMAX systems.Erceg, V., Greenstein, L. J., Tjandra, S. Y., Parkoff, S. R., Gupta, A., Kulic, B., … Bianchi, R. (1999). An empirically based path loss model for wireless channels in suburban environments. IEEE Journal on Selected Areas in Communications, 17(7), 1205-1211. doi:10.1109/49.778178Farhoud, M., El-Keyi, A., & Sultan, A. (2013). Empirical correction of the Okumura-Hata model for the 900 MHz band in Egypt. 2013 Third International Conference on Communications and Information Technology (ICCIT). doi:10.1109/iccitechnology.2013.6579585Faruk, N., Adediran, Y. A., & Ayeni, A. A. (2013). Error bounds of empirical path loss models at VHF/UHF bands in Kwara State, Nigeria. Eurocon 2013. doi:10.1109/eurocon.2013.6625043Faruk, N., Ayeni, A., & Adediran, Y. A. (2013). ON THE STUDY OF EMPIRICAL PATH LOSS MODELS FOR ACCURATE PREDICTION OF TV SIGNAL FOR SECONDARY USERS. Progress In Electromagnetics Research B, 49, 155-176. doi:10.2528/pierb13011306Hata, M. (1980). Empirical formula for propagation loss in land mobile radio services. IEEE Transactions on Vehicular Technology, 29(3), 317-325. doi:10.1109/t-vt.1980.23859Hufford, G. A. (1952). An integral equation approach to the problem of wave propagation over an irregular surface. Quarterly of Applied Mathematics, 9(4), 391-404. doi:10.1090/qam/44350Ibhaze, A. E., Ajose, S. O., Atayero, A. A.-A., & Idachaba, F. E. (2016). Developing smart cities through optimal wireless mobile network.Paper presented at the emerging technologies and innovative business practices for the transformation of societies (EmergiTech), IEEE international conference on.Luebbers, R. (1984). Propagation prediction for hilly terrain using GTD wedge diffraction. IEEE Transactions on Antennas and Propagation, 32(9), 951-955. doi:10.1109/tap.1984.1143449Matthews, V. O., Osuoyah, Q., Popoola, S. I., Adetiba, E., & Atayero, A. A. (2017, July 5–7). C-BRIG: A network architecture for real-time information exchange in smart and connected campuses. In Lecture notes in engineering and computer science: Proceedings of the world congress on engineering 2017 (pp. 398–401). London.Medeisis, A., & Kajackas, A. (s. f.). On the use of the universal Okumura-Hata propagation prediction model in rural areas. VTC2000-Spring. 2000 IEEE 51st Vehicular Technology Conference Proceedings (Cat. No.00CH37026). doi:10.1109/vetecs.2000.851585Mohtashami, V., & Shishegar, A. A. (2012). Modified wavefront decomposition method for fast and accurate ray-tracing simulation. IET Microwaves, Antennas & Propagation, 6(3), 295. doi:10.1049/iet-map.2011.0264Nimavat, V. D., & Kulkarni, G. (2012). Simulation and performance evaluation of GSM propagation channel under the urban, suburban and rural environments.Paper presented at the communication, information & computing technology (ICCICT), 2012 international conference on.. O. F. O. (2014). RADIO FREQUENCY OPTIMIZATION OF MOBILE NETWORKS IN ABEOKUTA, NIGERIA FOR IMPROVED QUALITY OF SERVICE. International Journal of Research in Engineering and Technology, 03(08), 174-180. doi:10.15623/ijret.2014.0308027Phillips, C., Sicker, D., & Grunwald, D. (2013). A Survey of Wireless Path Loss Prediction and Coverage Mapping Methods. IEEE Communications Surveys & Tutorials, 15(1), 255-270. doi:10.1109/surv.2012.022412.00172Popoola, S. I., Atayero, A. A., Badejo, J. A., John, T. M., Odukoya, J. A., & Omole, D. O. (2018). Learning analytics for smart campus: Data on academic performances of engineering undergraduates in Nigerian private university. Data in Brief, 17, 76-94. doi:10.1016/j.dib.2017.12.059Popoola, S. I., Atayero, A. A., & Faruk, N. (2018). Received signal strength and local terrain profile data for radio network planning and optimization at GSM frequency bands. Data in Brief, 16, 972-981. doi:10.1016/j.dib.2017.12.036Popoola, S. I., Atayero, A. A., Faruk, N., & Badejo, J. A. (2018). Data on the key performance indicators for quality of service of GSM networks in Nigeria. Data in Brief, 16, 914-928. doi:10.1016/j.dib.2017.12.005Popoola, S. I., Atayero, A. A., Faruk, N., Calafate, C. T., Adetiba, E., & Matthews, V. O. (2017, July 5–7). Calibrating the standard path loss model for urban environments using field measurements and geospatial data.Paper presented at the Lecture notes in engineering and computer science: Proceedings of the world congress on engineering 2017 (pp. 513–518). London.Popoola, S. I., Atayero, A. A., Faruk, N., Calafate, C. T., Olawoyin, L. A., & Matthews, V. O. (2017). Standard propagation model tuning for path loss predictions in built-up environments.Paper presented at the International Conference on Computational Science and Its Applications.Popoola, S. I., Atayero, A. A., Okanlawon, T. T., Omopariola, B. I., & Takpor, O. A. (2018). Smart campus: Data on energy consumption in an ICT-driven university. Data in Brief, 16, 780-793. doi:10.1016/j.dib.2017.11.091Popoola, S. I., Badejo, J. A., Ojewande, S. O., & Atayero, A. (2017, October 25–27). Statistical evaluation of quality of service offered by GSM network operators in Nigeria. In Lecture notes in engineering and computer science: Proceedings of the world congress on engineering and computer science 2017 (pp. 69–73). San Francisco.Popoola, S. I., Misra, S., & Atayero, A. A. (2018). Outdoor path loss predictions based on extreme learning machine. Wireless Personal Communications, 1–20.Rath, H. K., Verma, S., Simha, A., & Karandikar, A. (2016). Path Loss model for Indian terrain-empirical approach.Paper presented at the communication (NCC), 2016 twenty second national conference on.Salman, M. A., Popoola, S. I., Faruk, N., Surajudeen-Bakinde, N., Oloyede, A. A., & Olawoyin, L. A. (2017). Adaptive neuro-fuzzy model for path loss prediction in the VHF band.Paper presented at the computing networking and informatics (ICCNI), 2017 international conference on.Schneider, I., Lambrecht, F., & Baier, A. (s. f.). Enhancement of the Okumura-Hata propagation model using detailed morphological and building data. Proceedings of PIMRC ’96 - 7th International Symposium on Personal, Indoor, and Mobile Communications. doi:10.1109/pimrc.1996.567508Sotiroudis, S. P., & Siakavara, K. (2015). Mobile radio propagation path loss prediction using Artificial Neural Networks with optimal input information for urban environments. AEU - International Journal of Electronics and Communications, 69(10), 1453-1463. doi:10.1016/j.aeue.2015.06.014Zelley, C. A., & Constantinou, C. C. (1999). A three-dimensional parabolic equation applied to VHF/UHF propagation over irregular terrain. IEEE Transactions on Antennas and Propagation, 47(10), 1586-1596. doi:10.1109/8.80590

An overview of burst, buckling, durability and corrosion analysis of lightweight FRP composite pipes and their applicability

© 2019 Elsevier Ltd. All rights reserved.The main aim of this review article was to address the performance of filament wound fibre reinforced polymer (FRP) composite pipes and their critical properties, such as burst, buckling, durability and corrosion. The importance of process parameters concerning merits and demerits of the manufacturing methods was discussed for the better-quality performance. Burst analysis revealed that the winding angle of ±55° was observed to be optimum with minimum failure mechanisms, such as matrix cracking, whitening, leakage and fracture. The reduction of buckling effect was reported in case of lower hoop stress value in the hoop to axial stress ratio against axial, compression and torsion. A significant improvement in energy absorption was observed in the hybrid composite pipes with the effect of thermal treatment. However, the varying winding angle in FRP pipe fabrication was reported as an influencing factor affecting all the aforementioned properties. Almost 90% of the reviewed studies was done using E-glass/epoxy materials for the composite pipe production. By overcoming associated limitations, such as replacing synthetic materials, designing new material combinations and cost-benefit analysis, the production cost of the lightweight FRP composite pipes can be decreased for the real-time applications.Peer reviewe