Ellipsometry noise spectrum, suspension transfer function measurement and closed-loop control of the suspension system in the Q & A experiment

The Q & A experiment, aiming at the detection of vacuum birefringence predicted by quantum electrodynamics, consists mainly of a suspended 3.5 m Fabry-Perot cavity, a rotating permanent dipole magnet and an ellipsometer. The 2.3 T magnet can rotate up to 10 rev/s, introducing an ellipticity signal at twice the rotation frequency. The X-pendulum gives a good isolation ratio for seismic noise above its main resonant frequency 0.3 Hz. At present, the ellipsometry noise decreases with frequency, from 1*10^{-5} rad Hz^{-1/2} at 5 Hz, 2*10^{-6} rad Hz^{-1/2} at 20 Hz to 5*10^{-7} rad Hz^{-1/2} at 40 Hz. The shape of the noise spectrum indicates possible improvement can be made by further reducing the movement between the cavity mirrors. From the preliminary result of yaw motion alignment control, it can be seen that some peaks due to yaw motion of the cavity mirror was suppressed. In this paper, we first give a schematic view of the Q & A experiment, and then present the measurement of transfer function of the compound X-pendulum-double pendulum suspension. A closed-loop control was carried out to verify the validity of the measured transfer functions. The ellipsometry noise spectra with and without yaw alignment control and the newest improvement is presented.Comment: 7 pages, 5 figures, presented in 6th Edoardo Amaldi Conference on Gravitational Waves, June 2005, Okinawa Japan and submitted to Journal of Physics: Conference Series. Some modifications are made according to the referee's comments: mainly to explain the relation between the displacement of cavity mirror and the ellipticity noise spectru

The crystal structure of the Y140F mutant of ADP-l-glycero-d-manno-heptose 6-epimerase bound to ADP-β-d-mannose suggests a one base mechanism

Bacteria synthesize a wide array of unusual carbohydrate molecules, which they use in a variety of ways. The carbohydrate l-glycero-d-manno-heptose is an important component of lipopolysaccharide and is synthesized in a complex series of enzymatic steps. One step involves the epimerization at the C6″ position converting ADP-d-glycero-d-manno-heptose into ADP-l-glycero-d-manno-heptose. The enzyme responsible is a member of the short chain dehydrogenase superfamily, known as ADP-l-glycero-d-manno-heptose 6-epimerase (AGME). The structure of the enzyme was known but the arrangement of the catalytic site with respect to the substrate is unclear. We now report the structure of AGME bound to a substrate mimic, ADP-β-d-mannose, which has the same stereochemical configuration as the substrate. The complex identifies the key residues and allows mechanistic insight into this novel enzyme

Supramolecular assemblies involving metal organic ring interactions: Heterometallic Cu(II)-Ln(III) two dimensional coordination polymers

Three isostructural two-dimensional coordination polymers of the general formula [Ln2(CuL)3(H2O)9]$5.5H2O, where Ln is La (1), Nd (2), and Gd (3), have been synthesized and isolated from aqueous solutions and their single-crystal structures determined by X-ray diffraction. The supramolecular interaction between the non-aromatic metallorings plays an important role in stabilizing the structure of these compounds. The thermal stability, reversible solvent uptake, electronic properties and magnetic studies of these compounds are also reported

Brill–Noether general K3 surfaces with the maximal number of elliptic pencils of minimal degree

We explicitly construct Brill–Noether general K3 surfaces of genus 4, 6 and 8 having the maximal number of elliptic pencils of degrees 3, 4 and 5, respectively, and study their moduli spaces and moduli maps to the moduli space of curves. As an application we prove the existence of Brill–Noether general K3 surfaces of genus 4 and 6 without stable Lazarsfeld–Mukai bundles of minimal c2.publishedVersio

A comparison of substrate oxidation during prolonged exercise in men at terrestrial altitude and normobaric normoxia following the coingestion of 13C glucose and 13C fructose

This study compared the effects of co-ingesting glucose and fructose on exogenous and endogenous substrate oxidation during prolonged exercise at altitude and sea level, in men. Seven male British military personnel completed two bouts of cycling at the same relative workload (55% Wmax) for 120 minutes on acute exposure to altitude (3375m) and at sea level (~113m). In each trial, participants ingested 1.2 g.min-1 of glucose (enriched with 13C glucose) and 0.6 g.min-1 of fructose (enriched with 13C fructose) directly before and every 15 minutes during exercise. Indirect calorimetry and isotope ratio mass spectrometry were used to calculate fat oxidation, total and exogenous carbohydrate oxidation, plasma glucose oxidation and endogenous glucose oxidation derived from liver and muscle glycogen. Total carbohydrate oxidation during the exercise period was lower at altitude (157.7±56.3 grams) than sea level (286.5±56.2 grams, P=0.006, ES=2.28), whereas fat oxidation was higher at altitude (75.5±26.8 grams) than sea level (42.5±21.3 grams, P=0.024, ES=1.23). Peak exogenous carbohydrate oxidation was lower at altitude (1.13±0.2 g.min-1) than sea level (1.42±0.16 g.min-1, P=0.034, ES=1.33). There were no differences in rates, or absolute and relative contributions of plasma or liver glucose oxidation between conditions during the second hour of exercise. However, absolute and relative contributions of muscle glycogen during the second hour were lower at altitude (29.3±28.9 grams, 16.6±15.2%) than sea level (78.7±5.2 grams (P=0.008, ES=1.71), 37.7±13.0% (P=0.016, ES=1.45). Acute exposure to altitude reduces the reliance on muscle glycogen and increases fat oxidation during prolonged cycling in men, compared with sea level

Can the Pioneer anomaly be of gravitational origin? A phenomenological answer

In order to satisfy the equivalence principle, any non-conventional mechanism proposed to gravitationally explain the Pioneer anomaly, in the form in which it is presently known from the so-far analyzed Pioneer 10/11 data, cannot leave out of consideration its impact on the motion of the planets of the Solar System as well, especially those orbiting in the regions in which the anomalous behavior of the Pioneer probes manifested itself. In this paper we, first, discuss the residuals of the right ascension \alpha and declination \delta of Uranus, Neptune and Pluto obtained by processing various data sets with different, well established dynamical theories (JPL DE, IAA EPM, VSOP). Second, we use the latest determinations of the perihelion secular advances of some planets in order to put on the test two gravitational mechanisms recently proposed to accommodate the Pioneer anomaly based on two models of modified gravity. Finally, we adopt the ranging data to Voyager 2 when it encountered Uranus and Neptune to perform a further, independent test of the hypothesis that a Pioneer-like acceleration can also affect the motion of the outer planets of the Solar System. The obtained answers are negative.Comment: Latex2e, 26 pages, 6 tables, 2 figure, 47 references. It is the merging of gr-qc/0608127, gr-qc/0608068, gr-qc/0608101 and gr-qc/0611081. Final version to appear in Foundations of Physic

Effect of Dietary Components on Larval Life History Characteristics in the Medfly (Ceratitis capitata: Diptera, Tephritidae)

Background: The ability to respond to heterogenous nutritional resources is an important factor in the adaptive radiation of insects such as the highly polyphagous Medfly. Here we examined the breadth of the Medfly’s capacity to respond to different developmental conditions, by experimentally altering diet components as a proxy for host quality and novelty. Methodology/Principal Findings: We tested responses of larval life history to diets containing protein and carbohydrate components found in and outside the natural host range of this species. A 40% reduction in the quantity of protein caused a significant increase in egg to adult mortality by 26.5%±6% in comparison to the standard baseline diet. Proteins and carbohydrates had differential effects on larval versus pupal development and survival. Addition of a novel protein source, casein (i.e. milk protein), to the diet increased larval mortality by 19.4%±3% and also lengthened the duration of larval development by 1.93±0.5 days in comparison to the standard diet. Alteration of dietary carbohydrate, by replacing the baseline starch with simple sugars, increased mortality specifically within the pupal stage (by 28.2%±8% and 26.2%±9% for glucose and maltose diets, respectively). Development in the presence of the novel carbohydrate lactose (milk sugar) was successful, though on this diet there was a decrease of 29.8±1.6 µg in mean pupal weight in comparison to pupae reared on the baseline diet. Conclusions: The results confirm that laboratory reared Medfly retain the ability to survive development through a wide range of fluctuations in the nutritional environment. We highlight new facets of the responses of different stages of holometabolous life histories to key dietary components. The results are relevant to colonisation scenarios and key to the biology of this highly invasive species