285 research outputs found
Trace checking of Metric Temporal Logic with Aggregating Modalities using MapReduce
Modern complex software systems produce a large amount of execution data,
often stored in logs. These logs can be analyzed using trace checking
techniques to check whether the system complies with its requirements
specifications. Often these specifications express quantitative properties of
the system, which include timing constraints as well as higher-level
constraints on the occurrences of significant events, expressed using aggregate
operators. In this paper we present an algorithm that exploits the MapReduce
programming model to check specifications expressed in a metric temporal logic
with aggregating modalities, over large execution traces. The algorithm
exploits the structure of the formula to parallelize the evaluation, with a
significant gain in time. We report on the assessment of the implementation -
based on the Hadoop framework - of the proposed algorithm and comment on its
scalability.Comment: 16 pages, 6 figures, Extended version of the SEFM 2014 pape
Efficient Large-scale Trace Checking Using MapReduce
The problem of checking a logged event trace against a temporal logic
specification arises in many practical cases. Unfortunately, known algorithms
for an expressive logic like MTL (Metric Temporal Logic) do not scale with
respect to two crucial dimensions: the length of the trace and the size of the
time interval for which logged events must be buffered to check satisfaction of
the specification. The former issue can be addressed by distributed and
parallel trace checking algorithms that can take advantage of modern cloud
computing and programming frameworks like MapReduce. Still, the latter issue
remains open with current state-of-the-art approaches.
In this paper we address this memory scalability issue by proposing a new
semantics for MTL, called lazy semantics. This semantics can evaluate temporal
formulae and boolean combinations of temporal-only formulae at any arbitrary
time instant. We prove that lazy semantics is more expressive than standard
point-based semantics and that it can be used as a basis for a correct
parametric decomposition of any MTL formula into an equivalent one with
smaller, bounded time intervals. We use lazy semantics to extend our previous
distributed trace checking algorithm for MTL. We evaluate the proposed
algorithm in terms of memory scalability and time/memory tradeoffs.Comment: 13 pages, 8 figure
Global convergence of COVID-19 basic reproduction number and estimation from early-time SIR dynamics
The SIR ('susceptible-infectious-recovered') formulation is used to uncover the generic spread mechanisms observed by COVID-19 dynamics globally, especially in the early phases of infectious spread. During this early period, potential controls were not effectively put in place or enforced in many countries. Hence, the early phases of COVID-19 spread in countries where controls were weak offer a unique perspective on the ensemble-behavior of COVID-19 basic reproduction number Ro inferred from SIR formulation. The work here shows that there is global convergence (i.e., across many nations) to an uncontrolled Ro = 4.5 that describes the early time spread of COVID-19. This value is in agreement with independent estimates from other sources reviewed here and adds to the growing consensus that the early estimate of Ro = 2.2 adopted by the World Health Organization is low. A reconciliation between power-law and exponential growth predictions is also featured within the confines of the SIR formulation. The effects of testing ramp-up and the role of 'super-spreaders' on the inference of Ro are analyzed using idealized scenarios. Implications for evaluating potential control strategies from this uncontrolled Ro are briefly discussed in the context of the maximum possible infected fraction of the population (needed to assess health care capacity) and mortality (especially in the USA given diverging projections). Model results indicate that if intervention measures still result in Ro > 2.7 within 44 days after first infection, intervention is unlikely to be effective in general for COVID-19
Controlling the Frequency-Temperature Sensitivity of a Cryogenic Sapphire Maser Frequency Standard by Manipulating Fe3+ Spins in the Sapphire Lattice
To create a stable signal from a cryogenic sapphire maser frequency standard,
the frequency-temperature dependence of the supporting Whispering Gallery mode
must be annulled. We report the ability to control this dependence by
manipulating the paramagnetic susceptibility of Fe3+ ions in the sapphire
lattice. We show that the maser signal depends on other Whispering Gallery
modes tuned to the pump signal near 31 GHz, and the annulment point can be
controlled to exist between 5 to 10 K depending on the Fe3+ ion concentration
and the frequency of the pump. This level of control has not been achieved
previously, and will allow improvements in the stability of such devices.Comment: 17 pages, 10 figure
Perinatal-lethal Gaucher disease presenting as hydrops fetalis
Perinatal-lethal Gaucher disease is very rare and is considered a variant of type 2 Gaucher disease that occurs in the neonatal period. The most distinct features of perinatal-lethal Gaucher disease are non-immune hydrops fetalis. Less common signs of the disease are hepatosplenomegaly, ichthyosis and arthrogryposis. We report a case of Gaucher's disease (type 2) diagnosed in a newborn who presented with Hydrops Fetalis
The role of the CNR1 gene in schizophrenia: a systematic review including unpublished data
Objective: Schizophrenia is a multifactorial disorder. It is known that a combination of extensive multiple common alleles may be involved in its etiology, each contributing with a small to moderate effect, and, possibly, some rare alleles with a much larger effect size. We aimed to perform a systematic review of association studies between schizophrenia (and its subphenotypes) and polymorphisms in the CNR1 gene, which encodes cannabinoid receptors classically implicated in schizophrenia pathophysiology, as well as to present unpublished results of an association study in a Brazilian population. Methods: Two reviewers independently searched for eligible studies and extracted outcome data using a structured form. Papers were retrieved from PubMed and ISI Web of Knowledge using the search term schizophrenia in combination with CNR1 or CB1 or cannabinoid receptor. Twenty-four articles met our inclusion criteria. We additionally present data from a study of our own comparing 182 patients with schizophrenia and 244 healthy controls. Results: No consistent evidence is demonstrated. Conclusion: Some seemingly positive association studies stress the need for further investigations of the possible role of endocannabinoid genetics in schizophrenia.Fundacao de Amparo e Pesquisa do Estado de Sao Paulo (FAPESP) [2010/08968-6, 2011/50740-5, 2011/00030-1]Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)FAPESPCNPqCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)Fundacao SafraFundacao ABADSUniv Fed Sao Paulo UNIFESP, Dept Psiquiatria, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Lab Interdisciplinar Neurociencias Clin LiNC, Sao Paulo, SP, BrazilIrmandade Santa Casa Misericordia Sao Paulo, Dept Psiquiatria, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Morfol & Genet, Sao Paulo, SP, BrazilUniv Fed Sao Paulo UNIFESP, Dept Psiquiatria, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Lab Interdisciplinar Neurociencias Clin LiNC, Sao Paulo, SP, BraziWeb of Scienc
A New Zn(II) Metal Hybrid Material of 5-Nitrobenzimidazolium Organic Cation (C7H6N3O2)2[ZnCl4]: Elaboration, Structure, Hirshfeld Surface, Spectroscopic, Molecular Docking Analysis, Electric and Dielectric Properties
The slow solvent evaporation approach was used to create a single crystal of (CHNO)[ZnCl] at room temperature. Our compound has been investigated by single-crystal XRD which declares that the complex crystallizes in the monoclinic crystallographic system with the P2/c as a space group. The molecular arrangement of the compound can be described by slightly distorted tetrahedral ZnCl anionic entities and 5-nitrobenzimidazolium as cations, linked together by different non-covalent interaction types (H-bonds, Cl…Cl, π…π and C–H…π). Hirshfeld’s surface study allows us to identify that the dominant contacts in the crystal building are H…Cl/Cl…H contacts (37.3%). FT-IR method was used to identify the different groups in (CHNO)[ZnCl]. Furthermore, impedance spectroscopy analysis in 393 ≤ T ≤ 438 K shows that the temperature dependence of DC conductivity follows Arrhenius’ law. The frequency–temperature dependence of AC conductivity for the studied sample shows one region (E = 2.75 eV). In order to determine modes of interactions of compound with double stranded DNA, molecular docking simulations were performed at molecular level
Impact of biodiesel fuel on cold starting of automotive direct injection diesel engines
The use of biodiesel fuels in diesel engines is gaining attention as a promising solution to control CO2
emissions. Great research efforts have been carried out to identify the impact of biodiesel physical and
chemical properties on engine systems and processes. Most of these investigations were performed in
warm conditions, but the suitability of biodiesel for starting the engine at under-zero ambient temperatures
has not widely evaluated. The surface tension and the viscosity of biodiesel fuels are higher
compared to those of standard diesel and, in cold conditions, these differences become critical since the
injection fuel rate is largely affected and consequently the combustion process can be deteriorated. In
order to improve its flow characteristics at cold temperatures and make them more suitable for low
temperatures operation, additives are used in biodiesel fuels. In this paper the suitability of different
biodiesel fuels, with and without additives, for cold starting of DI (direct injection) diesel engines has
been evaluated. The results have shown that the engine start-ability with pure biodiesel fuels can be
largely deteriorated. However, using diesel/biodiesel blends the start-ability of the engine can be
recovered with the additional benefit of reducing the opacity peak of the exhaust gasesBroatch Jacobi, JA.; Tormos Martínez, BV.; Olmeda González, PC.; Novella Rosa, R. (2014). Impact of biodiesel fuel on cold starting of automotive direct injection diesel engines. Energy. 73:653-660. doi:10.1016/j.energy.2014.06.062S6536607
Ideas del alumnado de primaria y secundaria sobre aleatoriedad
En este trabajo comparamos las características de las secuencias de resultados
aleatorios y distribuciones aleatorias de puntos generadas por tres grupos de alumnos
de Educación Primaria y Secundaria con las propiedades matemáticas de las mismas.
La finalidad es describir el significado personal que dichos estudiantes asignan a la
aleatoriedad.In this paper we compare the features in random sequences and random distribution
of points produced by three groups of students in Primary and Secondary Education
with the mathematical properties of the same. The aim is to describe the meaning of
randomness for these students.Facultad de Educación y Humanidades - Campus de Melilla (Universidad de Granada)Este trabajo es parte de los proyectos SEJ2004-00789, Madrid, MCYT y FQM-126, Junta de Andalucí
Peak grain forecasts for the US High Plains amid withering waters
ACKNOWLEDGMENTS. This paper stems from discussions during the Ettersburg Ecohydrology Workshop in Germany (October 2018), with the corresponding manuscript preparation ensuing in subsequent months. The workshop was funded by the UNIDEL Foundation, Inc. and the University of Delaware. Accordingly, partial support for this paper derived from funding for the workshop. A.M. was supported by the US NSF (Grants NSF-AGS-1644382 and NSF-IOS-175489).Peer reviewedPublisher PD
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