Antifungal susceptibilities, varieties, and electrophoretic karyotypes of clinical isolates of Cryptococcus neoformans from Brazil, Chile, and Venezuela

One hundred clinical isolates of Cryptococcus neoformans from human immunodeficiency virus (HIV)-infected and non-HIV-infected patients from Brazil, Chile, and Venezuela were separated according to varieties and tested for antifungal susceptibility. A high susceptibility to antifungal agents was observed among all the isolates. The electrophoretic karyotyping of 51 strains revealed good discrimination among Cryptococcus neoformans var. neoformans strains.3962348235

Expected properties of the Two-Point Autocorrelation Function of the IGM

Recent analyses of the fluctuations of the soft Diffuse X-ray Background (DXB) have provided indirect detection of a component consistent with the elusive Warm Hot Intergalactic Medium (WHIM). In this work we use theoretical predictions obtained from hydrodynamical simulations to investigate the angular correlation properties of the WHIM in emission and assess the possibility of indirect detection with next-generation X-ray missions. Our results indicate that the angular correlation signal of the WHIM is generally weak but dominates the angular correlation function of the DXB outside virialized regions. Its indirect detection is possible but requires rather long exposure times [0.1-1] Ms, large (~1{\deg} x1{\deg}) fields of view and accurate subtraction of isotropic fore/background contributions, mostly contributed by Galactic emission. The angular correlation function of the WHIM is positive for {\theta} < 5' and provides limited information on its spatial distribution. A satisfactory characterization of the WHIM in 3D can be obtained through spatially resolved spectroscopy. 1 Ms long exposures with next generation detectors will allow to detect ~400 O VII+O VIII X-ray emission systems that we use to trace the spatial distribution of the WHIM. We predict that these observations will allow to estimate the WHIM correlation function with high statistical significance out to ~10 Mpc h^-1 and characterize its dynamical state through the analysis of redshift-space distortions. The detectable WHIM, which is typically associated with the outskirts of virialized regions rather than the filaments has a non-zero correlation function with slope {\gamma} = -1.7 \pm 0.1 and correlation length r0 = 4.0 \pm 0.1 Mpc h^-1 in the range r = [4.5, 12] Mpc h^-1. Redshift space distances can be measured to assess the dynamical properties of the gas, typically infalling onto large virialized structures.Comment: 17 pages, 2 tables, 11 figures, Final version, accepted for publication on MNRA

Euclid: Modelling massive neutrinos in cosmology -- a code comparison

The measurement of the absolute neutrino mass scale from cosmological large-scale clustering data is one of the key science goals of the Euclid mission. Such a measurement relies on precise modelling of the impact of neutrinos on structure formation, which can be studied with $N$-body simulations. Here we present the results from a major code comparison effort to establish the maturity and reliability of numerical methods for treating massive neutrinos. The comparison includes eleven full $N$-body implementations (not all of them independent), two $N$-body schemes with approximate time integration, and four additional codes that directly predict or emulate the matter power spectrum. Using a common set of initial data we quantify the relative agreement on the nonlinear power spectrum of cold dark matter and baryons and, for the $N$-body codes, also the relative agreement on the bispectrum, halo mass function, and halo bias. We find that the different numerical implementations produce fully consistent results. We can therefore be confident that we can model the impact of massive neutrinos at the sub-percent level in the most common summary statistics. We also provide a code validation pipeline for future reference.Comment: 43 pages, 17 figures, 2 tables; published on behalf of the Euclid Consortium; data available at https://doi.org/10.5281/zenodo.729797

<em>Euclid</em> preparation: XLVII. Improving cosmological constraints using a new multi-tracer method with the spectroscopic and photometric samples

\ua9 2024 The Authors. Future data provided by the Euclid mission will allow us to better understand the cosmic history of the Universe. A metric of its performance is the figure-of-merit (FoM) of dark energy, usually estimated with Fisher forecasts. The expected FoM has previously been estimated taking into account the two main probes of Euclid, namely the three-dimensional clustering of the spectroscopic galaxy sample, and the so-called 3 72pt signal from the photometric sample (i.e., the weak lensing signal, the galaxy clustering, and their cross-correlation). So far, these two probes have been treated as independent. In this paper, we introduce a new observable given by the ratio of the (angular) two-point correlation function of galaxies from the two surveys. For identical (normalised) selection functions, this observable is unaffected by sampling noise, and its variance is solely controlled by Poisson noise. We present forecasts for Euclid where this multi-tracer method is applied and is particularly relevant because the two surveys will cover the same area of the sky. This method allows for the exploitation of the combination of the spectroscopic and photometric samples. When the correlation between this new observable and the other probes is not taken into account, a significant gain is obtained in the FoM, as well as in the constraints on other cosmological parameters. The benefit is more pronounced for a commonly investigated modified gravity model, namely the γ parametrisation of the growth factor. However, the correlation between the different probes is found to be significant and hence the actual gain is uncertain. We present various strategies for circumventing this issue and still extract useful information from the new observable

First isolation of Candida dubliniensis in Rio grande do sul, Brazil

Candida dubliniensis is a newly recognized species closely phylogenetically related to Candida albicans and is commonly associated with oral candidiasis in human immunodeficiency virus-positive patients. in this paper we report the isolation of three strains of C. dubliniensis, from AIDS patients, in the state of Rio Grande do Sul (Brazil). the phenotypic identification was based on germ tube emission, abundant production of chlamydospores, assimilation of sucrose but not of xylose and the inability to grow at 42 degreesC. Randomly amplified polymorphic DNA (RAPD) analysis and genomic DNA sequencing confirmed the distinct genetic nature C. dubliniensis. Topics related to the epidemiology, isolation, phenotypical and genotypical identification of C, dubliniensis are also discussed. (C) 2001 Elsevier Science Inc. All rights reserved.Univ Fed Santa Maria, Hosp Santa Maria, BR-97119900 Santa Maria, RS, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Div Infect Dis, São Paulo, BrazilUniv Campinas, UNICAMP, Div Infect Dis, Campinas, BrazilChiba Univ, Pathogen Fungi & Microbial Toxicoses Res Ctr, Chiba 280, JapanUniversidade Federal de São Paulo, Escola Paulista Med, Div Infect Dis, São Paulo, BrazilWeb of Scienc

Antifungal susceptibilities, varieties, and electrophoretic karyotypes of clinical isolates of Cryptococcus neoformans from Brazil, Chile and Venezuela

Artigo encontra-se disponível em acesso aberto no site do Editor.Submitted by Repositório Arca ([email protected]) on 2019-04-24T12:23:04Z No. of bitstreams: 1 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)Approved for entry into archive by Janaína Nascimento ([email protected]) on 2019-06-20T18:00:20Z (GMT) No. of bitstreams: 2 ve_Calvo_Belinda_etal_INI_2001.pdf: 212025 bytes, checksum: bf16ea470c4361b8dfa39222f8601db0 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)Made available in DSpace on 2019-06-20T18:00:20Z (GMT). No. of bitstreams: 2 ve_Calvo_Belinda_etal_INI_2001.pdf: 212025 bytes, checksum: bf16ea470c4361b8dfa39222f8601db0 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2001Universidad del Zulia-Luz. Maracaibo, Venezuela.Clínica Santa María. Santiago, Chile.Clínica Santa María. Santiago, Chile.Hospital Clínico de Caracas, Caracas, Venezuela.Clínica Santa María, Santiago, ChileFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Universidade Federal de Paraná. Curitiba, PR, Brasil.Chiba University. Chiba, Japan.Chiba University. Chiba, Japan.Chiba University. Chiba, Japan.Chiba University. Chiba, Japan.Universidade Estadual de Campinas. Campinas, SP, Brasil.One hundred clinical isolates of Cryptococcus neoformans from human immunodeficiency virus (HIV)-infected and non-HIV-infected patients from Brazil, Chile, and Venezuela were separated according to varieties and tested for antifungal susceptibility. A high susceptibility to antifungal agents was observed among all the isolates. The electrophoretic karyotyping of 51 strains revealed good discrimination among Cryptococcus neoformans var. neoformans strains

Phaeohyphomycosis Caused By Chaetomium Globosum In An Allogeneic Bone Marrow Transplant Recipient.

Bone marrow transplant recipients are highly susceptible to opportunistic fungal infections. This is the report, of the first case of a Chaetomium systemic infection described in Brazil. A 34 year-old patient with chronic myeloid leukemia underwent an allogeneic sibling matched bone marrow transplant. Seven months later, he developed systemic infection with enlargement of the axillary and cervical lymph nodes. Culture of the aspirates from both lymph nodes yielded Chaetomium globosum. The infection was successfully treated with amphotericin B. The increasing population of immunosupressed patients requires a careful microbiologic investigation for uncommon fungal infections.156309-1

The perception and cognition of contraries

The inspiration for this book originated from an intention to show that in the architecture of human cognition the experience of contrariety is widespread and common to many areas of theoretical and experimental research in the Cognitive Sciences. Since the subject is approached with different operational mind-sets, the variety of meanings, applicative contexts and fields of research referring to the word "contrary" raises the issue of what is invariant in all these areas and what is the ultimate nature of contrariety. Beyond the many questions which this book raises, we might consider how many more questions we might need to ask in order to fully understand how contrariety works in our cognitive system. This is something that cannot be resolved with things as they are now, but the aim of this book is also to stimulate people into asking further questions. Preface The early roots of contrariety 1) The relation of contrariety in the ancient thought and in the Aristotelian formalization 2) The geometry of oppositions and the opposition of logic to it Contrariety in perception 3) The spatial path to contrariety 4) Investigating contraries by means of change detection 5) Contrariety in plane mirror reflections Contrariety in language and though 6) Basic qualities in na\uefve subjects\u2019 perception of voice. Are they based on contrary properties? 7) Are drag and push contraries? 8) Are certain and uncertain epistemic contraries? 9) Contraries in productive thinking 10) The perception of humor: from script opposition to the phenomenological rules of contrariety The unidimensionality of contraries 11) Measuring in experimental phenomenology and carrying out phenomenological psychophysics: the case of contrary properties 12) From opposites to dimensions: filling in the gaps 13) Reverse items are NOT opposites of straightforward item