Model-Driven End-to-End Learning for Integrated Sensing and Communication

Integrated sensing and communication (ISAC) is envisioned to be one of the pillars of 6G. However, 6G is also expected to be severely affected by hardware impairments. Under such impairments, standard model-based approaches might fail if they do not capture the underlying reality. To this end, data-driven methods are an alternative to deal with cases where imperfections cannot be easily modeled. In this paper, we propose a model-driven learning architecture for joint single- target multi-input multi-output (MIMO) sensing and multi-input single-output (MISO) communication. We compare it with a standard neural network approach under complexity constraints. Results show that under hardware impairments, both learning methods yield better results than the model-based standard baseline. If complexity constraints are further introduced, model- driven learning outperforms the neural-network-based approach. Model-driven learning also shows better generalization performance for new unseen testing scenario

End-to-End Learning for Integrated Sensing and Communication

Integrated sensing and communication (ISAC) aims to unify radar and communication systems through a combination of joint hardware, joint waveforms, joint signal design, and joint signal processing. At high carrier frequencies, where ISAC is expected to play a major role, joint designs are challenging due to several hardware limitations. Model-based approaches, while powerful and flexible, are inherently limited by how well the models represent reality. Under model deficit, data-driven methods can provide robust ISAC performance. We present a novel approach for data-driven ISAC using an auto-encoder (AE) structure. The approach includes the proposal of the AE architecture, a novel ISAC loss function, and the training procedure. Numerical results demonstrate the power of the proposed AE, in particular under hardware impairments

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research