7,081 research outputs found
Distinguishing Patients With a Coordination Disorder From Healthy Controls Using Local Features of Movement Trajectories During the Finger-to-Nose Test
Assessment of coordination disorders is valuable for monitoring progression of patients, distinguishing healthy and pathological conditions, and ultimately aiding in clinical decision making, thereby offering the possibility to improve medical care or rehabilitation. A common method to assess movement disorders is by using clinical rating scales. However, rating scales depend on the evaluation and interpretation of an observer, implying that subjective phenotypic assignment precedes the application of the scales. Objective and more accurate methods are under continuous development but gold standards are still scarce. Here, we show how a method we previously developed, originally aimed at assessing dynamic balance by a probabilistic generalized linear model, can be used to assess a broader range of functional movements. In this paper, the method is applied to distinguish patients with coordination disorders from healthy controls. We focused on movements recorded during the finger-to-nose task (FNT), which is commonly used to assess coordination disorders. We also compared clinical FNT scores and model scores. Our method achieved 84% classification accuracy in distinguishing patients and healthy participants, using only two features. Future work could entail testing the reliability of the method by using additional features and other clinical tests such as finger chasing, quiet standing, and/or usage of tracking devices such as depth cameras or force plates
MiniBooNE and LSND data: non-standard neutrino interactions in a (3+1) scheme versus (3+2) oscillations
The recently observed event excess in MiniBooNE anti-neutrino data is in
agreement with the LSND evidence for electron anti-neutrino appearance. We
propose an explanation of these data in terms of a (3+1) scheme with a sterile
neutrino including non-standard neutrino interactions (NSI) at neutrino
production and detection. The interference between oscillations and NSI
provides a source for CP violation which we use to reconcile different results
from neutrino and anti-neutrino data. Our best fit results imply NSI at the
level of a few percent relative to the standard weak interaction, in agreement
with current bounds. We compare the quality of the NSI fit to the one obtained
within the (3+1) and (3+2) pure oscillation frameworks. We also briefly comment
on using NSI (in an effective two-flavour framework) to address a possible
difference in neutrino and anti-neutrino results from the MINOS experiment.Comment: 28 pages, 9 figures, discussion improved, new appendix added,
conclusions unchange
Resonance-free Region in scattering by a strictly convex obstacle
We prove the existence of a resonance free region in scattering by a strictly
convex obstacle with the Robin boundary condition. More precisely, we show that
the scattering resonances lie below a cubic curve which is the same as in the
case of the Neumann boundary condition. This generalizes earlier results on
cubic poles free regions obtained for the Dirichlet boundary condition.Comment: 29 pages, 2 figure
Higgs production as a probe of anomalous top couplings
The LHC may be currently seeing the first hints of the Higgs boson. The
dominant production mode for the Higgs at the LHC involves a top-quark loop. An
accurate measurement of Higgs production cross-sections and decay widths can
thus be used to obtain limits on anomalous top couplings. We find that such an
exercise could potentially yield constraints that are stronger than those
derived from low-energy observables as well as direct bounds expected from the
top pair-production process.Comment: Version published in JHE
Measurement of Atmospheric Neutrino Oscillations with the ANTARES Neutrino Telescope
The data taken with the ANTARES neutrino telescope from 2007 to 2010, a total
live time of 863 days, are used to measure the oscillation parameters of
atmospheric neutrinos. Muon tracks are reconstructed with energies as low as 20
GeV. Neutrino oscillations will cause a suppression of vertical upgoing muon
neutrinos of such energies crossing the Earth. The parameters determining the
oscillation of atmospheric neutrinos are extracted by fitting the event rate as
a function of the ratio of the estimated neutrino energy and reconstructed
flight path through the Earth. Measurement contours of the oscillation
parameters in a two-flavour approximation are derived. Assuming maximum mixing,
a mass difference of eV is
obtained, in good agreement with the world average value.Comment: 9 pages, 5 figure
Model-Independent Searches for New Quarks at the LHC
New vector-like quarks can have sizable couplings to first generation quarks
without conflicting with current experimental constraints. The coupling with
valence quarks and unique kinematics make single production the optimal
discovery process. We perform a model-independent analysis of the discovery
reach at the Large Hadron Collider for new vector-like quarks considering
single production and subsequent decays via electroweak interactions. An early
LHC run with 7 TeV center of mass energy and 1 fb-1 of integrated luminosity
can probe heavy quark masses up to 1 TeV and can be competitive with the
Tevatron reach of 10 fb-1. The LHC with 14 TeV center of mass energy and 100
fb-1 of integrated luminosity can probe heavy quark masses up to 3.7 TeV for
order one couplings.Comment: 37 pages, 11 figures, 7 table
The minimal 3+2 neutrino model versus oscillation anomalies
We study the constraints imposed by neutrino oscillation experiments on the minimal extension of the Standard Model that can explain neutrino masses, which requires the addition of just two singlet Weyl fermions. The most general renormalizable couplings of this model imply generically four massive neutrino mass eigenstates while one remains massless: it is therefore a minimal 3+2 model. The possibility to account for the confirmed solar, atmospheric and long-baseline oscillations, together with the LSND/MiniBooNE and reactor anomalies is addressed. We find that the minimal model can fit oscillation data including the anomalies better than the standard 3ν model and similarly to the 3+2 phenomenological models, even though the number of free parameters is much smaller than in the latter. Accounting for the anomalies in the minimal model favours a normal hierarchy of the light states and requires a large reactor angle, in agreement with recent measurements. Our analysis of the model employs a new parametrization of seesaw models that extends the Casas-Ibarra one to regimes where higher order corrections in the light-heavy mixings are significant
Acoustic and optical variations during rapid downward motion episodes in the deep north-western Mediterranean Sea
An Acoustic Doppler Current Profiler (ADCP) was moored at the deep-sea site
of the ANTARES neutrino telescope near Toulon, France, thus providing a unique
opportunity to compare high-resolution acoustic and optical observations
between 70 and 170 m above the sea bed at 2475 m. The ADCP measured downward
vertical currents of magnitudes up to 0.03 m s-1 in late winter and early
spring 2006. In the same period, observations were made of enhanced levels of
acoustic reflection, interpreted as suspended particles including zooplankton,
by a factor of about 10 and of horizontal currents reaching 0.35 m s-1. These
observations coincided with high light levels detected by the telescope,
interpreted as increased bioluminescence. During winter 2006 deep dense-water
formation occurred in the Ligurian subbasin, thus providing a possible
explanation for these observations. However, the 10-20 days quasi-periodic
episodes of high levels of acoustic reflection, light and large vertical
currents continuing into the summer are not direct evidence of this process. It
is hypothesized that the main process allowing for suspended material to be
moved vertically later in the year is local advection, linked with topographic
boundary current instabilities along the rim of the 'Northern Current'.Comment: 30 pages, 7 figure
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