698 research outputs found
Relative Gains, Losses, and Reference Points in Probabilistic Choice in Rats
Citation: Marshall, A. T., & Kirkpatrick, K. (2015). Relative Gains, Losses, and Reference Points in Probabilistic Choice in Rats. Plos One, 10(2), 33. doi:10.1371/journal.pone.0117697Theoretical reference points have been proposed to differentiate probabilistic gains from probabilistic losses in humans, but such a phenomenon in non-human animals has yet to be thoroughly elucidated. Three experiments evaluated the effect of reward magnitude on probabilistic choice in rats, seeking to determine reference point use by examining the effect of previous outcome magnitude(s) on subsequent choice behavior. Rats were trained to choose between an outcome that always delivered reward (low-uncertainty choice) and one that probabilistically delivered reward (high-uncertainty). The probability of high-uncertainty outcome receipt and the magnitudes of low-uncertainty and high-uncertainty outcomes were manipulated within and between experiments. Both the low- and high-uncertainty outcomes involved variable reward magnitudes, so that either a smaller or larger magnitude was probabilistically delivered, as well as reward omission following high-uncertainty choices. In Experiments 1 and 2, the between groups factor was the magnitude of the high-uncertainty-smaller (H-S) and high-uncertainty-larger (H-L) outcome, respectively. The H-S magnitude manipulation differentiated the groups, while the H-L magnitude manipulation did not. Experiment 3 showed that manipulating the probability of differential losses as well as the expected value of the low-uncertainty choice produced systematic effects on choice behavior. The results suggest that the reference point for probabilistic gains and losses was the expected value of the low-uncertainty choice. Current theories of probabilistic choice behavior have difficulty accounting for the present results, so an integrated theoretical framework is proposed. Overall, the present results have implications for understanding individual differences and corresponding underlying mechanisms of probabilistic choice behavior
Mechanisms of Individual Differences in Impulsive and Risky Choice in Rats
Citation: Kirkpatrick, K., Marshall, A. T., & Smith, A. P. (2015). Mechanisms of Individual Differences in Impulsive and Risky Choice in Rats. Comparative Cognition & Behavior Reviews, 10. Retrieved from http://comparative-cognition-and-behavior-reviews.org/2015/vol10_kirkpatrick_marshall_smith/Mechanisms of Individual Differences in Impulsive and Risky Choice in Rats Kimberly Kirkpatrick Department of Psychological Sciences, Kansas State University Andrew T. Marshall Department of Psychological Sciences, Kansas State University Aaron P
Individual differences in impulsive and risky choice: effects of environmental rearing conditions
The present experiment investigated early-rearing environment modulation of individual differences in impulsive and risky choice. Rats were reared in an isolated condition (IC; n = 12), in which they lived alone without novel stimuli, or an enriched condition (EC; n = 12), in which they lived among conspecifics with novel stimuli. The impulsive choice task involved choices between smaller-sooner (SS) versus larger-later (LL) rewards. The risky choice task involved choices between certain-smaller (C-S) versus uncertain-larger (U-L) rewards. Following choice testing, incentive motivation to work for food was measured using a progressive ratio task and correlated with choice behavior. HPLC analyses were conducted to determine how monoamine concentrations within the prefrontal cortex (PFC) and nucleus accumbens (NAC) related to behavior in different tasks. IC rats were more impulsive than EC rats, but they did not differ in risky choice behavior. However, choice behavior across tasks was significantly correlated (i.e., the more impulsive rats were also riskier). There were no group differences in monoamine levels, but noradrenergic and serotonergic concentrations were significantly correlated with impulsive and risky choice. Furthermore, serotonin and norepinephrine concentrations in the NAC significantly correlated with incentive motivation and the timing of the reward delays within the choice tasks. These results suggest a role for domain general processes in impulsive and risky choice and indicate the importance of the NAC and/or PFC in timing, reward processing, and choice behavior
I can't wait: Methods for measuring and moderating individual differences in impulsive choice
Citation: Peterson, J. R., Hill, C. C., Marshall, A. T., Stuebing, S. L., & Kirkpatrick, K. (2015). I can't wait: Methods for measuring and moderating individual differences in impulsive choice. Journal of Agricultural and Food Industrial Organization, 13(1), 89-99. doi:10.1515/jafio-2015-0024Impulsive choice behavior occurs when individuals make choices without regard for future consequences. This behavior is often maladaptive and is a common symptom in many disorders, including drug abuse, compulsive gambling, and obesity. Several proposed mechanisms may influence impulsive choice behavior. These mechanisms provide a variety of pathways that may provide the basis for individual differences that are often evident when measuring choice behavior. This review provides an overview of these different pathways to impulsive choice, and the behavioral intervention strategies being developed to moderate impulsive choice. Because of the compelling link between impulsive choice behavior and the near-epidemic pervasiveness of obesity in the United States, we focus on the relationship between impulsive choice behavior and obesity as a test case for application of the multiple pathways approach. Choosing immediate gratification over healthier long term food choices is a contributing factor to the obesity crisis. Behavioral interventions can lead to more self-controlled choices in a rat pre-clinical model, suggesting a possible gateway for translation to human populations. Designing and implementing effective impulsive choice interventions is crucial to improving the overall health and well-being of impulsive individuals. © by De Gruyter 2015
The evolution of mutualism with modifiers
Mutualisms are widespread, yet their evolution has received less theoretical attention than within-species social behaviors. Here, we extend previous models of unconditional pairwise interspecies social behavior, to consider selection for donation but also for donation-suppressing modifiers. We present conditions under which modifiers that suppress costly donation receive either positive or negative selection; assortment only at the donation locus always leads to selection for donation suppression, as in within-species greenbeard traits. However, genomewide assortment with modifier loci can lead to intermediate levels of donation, and these can differ in the two species even when payoffs from donation are additive and symmetric. When costly donation between species can evolve without being suppressed, we argue that it is most appropriately explained by indirect fitness benefits within the donating species, using partner species as vectors for altruism. Our work has implications for identifying both the stability and the ultimate beneficiaries of social behavior between species
Identification of a Wide, Low-Mass Multiple System Containing the Brown Dwarf 2MASS J0850359+105716
We report our discovery of NLTT 20346 as an M5+M6 companion system to the
tight binary (or triple) L dwarf 2MASS J0850359+105716. This nearby (~31 pc),
widely separated (~7700 AU) quadruple system was identified through a
cross-match of proper motion catalogs. Follow-up imaging and spectroscopy of
NLTT 20346 revealed it to be a magnetically active M5+M6 binary with components
separated by ~2" (50-80 AU). Optical spectroscopy of the components show only
moderate Halpha emission corresponding to a statistical age of ~5 - 7 Gyr for
both M dwarfs. However NLTT 20346 is associated with the XMM-Newton source
J085018.9+105644, and based on X-ray activity the age of NLTT 20346 is between
250-450 Myr. Strong Li absorption in the optical spectrum of 2MASS J0850+1057
indicates an upper age limit of 0.8 - 1.5 Gyr favoring the younger age for the
primary. Using evolutionary models in combination with an adopted system age of
0.25-1.5 Gyr indicates a total mass for 2MASS J0850+1057 of 0.07+/-0.02 Msun if
it is a binary. NLTT 20346/2MASS J0850+1057 joins a growing list of
hierarchical systems containing brown dwarf binaries and is among the lowest
binding energy associations found in the field. Formation simulations via
gravitational fragmentation of massive extended disks have successfully
produced a specific analog to this system.Comment: 13 pages, accepted for publication to A
An Infrared High Proper Motion Survey Using 2MASS and SDSS: Discovery of M, L and T Dwarfs
A search of the Two Micron All Sky Survey and Sloan Digital Sky
Survey reveals 36 previously unknown high proper motion objects with
J<17. Their red-optical colors indicate that 27 are M dwarfs, 8 are
early-type L dwarfs, and 1 is a late-type T dwarf. The L dwarfs have J-Ks
colors near the extrema of known L dwarfs indicating that previous surveys for
L dwarfs using color as a selection criterion may be biased. Followup
near-infrared spectroscopy of 6 dwarfs confirm they are all late-type with
spectral types ranging from M8 to T4. Spectroscopy also shows that some of the
L dwarf spectra exhibit peculiar features similar to other peculiar "blue" L
dwarfs which may indicate that these dwarfs have a relatively condensate free
atmosphere or may be metal poor. Photometric distance estimates indicate that
22 of the new M, L and T dwarfs lie within 100 pc of the Sun with the newly
discovered T dwarf, 2MASS J10595185+3042059, located at about 25 pc. Based on
the colors and proper motions of the newly identified objects, several appear
to be good subdwarf candidates. The proper motions of known ultracool dwarfs
detected in our survey were also measured, including, for the first time, SDSS
J085834.42+325627.6 (T1), SDSS J125011.65+392553.9 (T4) and 2MASS
J15261405+2043414 (L7).Comment: 14 pages, 7 tables, 9 figures: Accepted for the January 2009 AJ issu
The What and Why of Research on Reinforcement
Reinforcement - a process that helps prevent interbreeding between hybridising populations - is an important and little understood mechanism driving the completion of speciatio
Uveal melanoma UK national guidelines
The United Kingdom (UK) uveal melanoma guideline development group used an evidence based systematic approach (Scottish Intercollegiate Guidelines Network (SIGN)) to make recommendations in key areas of uncertainty in the field including: the use and effectiveness of new technologies for prognostication, the appropriate pathway for the surveillance of patients following treatment for primary uveal melanoma, the use and effectiveness of new technologies in the treatment of hepatic recurrence and the use of systemic treatments. The guidelines were sent for international peer review and have been accredited by NICE. A summary of key recommendations is presented. The full documents are available on the Melanoma Focus website
A spectroscopic and proper motion search of Sloan Digital Sky Survey : red subdwarfs in binary systems
Red subdwarfs in binary systems are crucial for both model calibration and spectral classification. We search for red subdwarfs in binary systems from a sample of high proper motion objects with Sloan Digital Sky Survey spectroscopy. We present here discoveries from this search, as well as highlight several additional objects of interest. We find 30 red subdwarfs in wide binary systems including: two with spectral type of esdM5.5, 6 companions to white dwarfs and 3 carbon-enhanced red subdwarfs with normal red subdwarf companions. 15 red subdwarfs in our sample are partially resolved close binary systems. With this binary sample, we estimate the low limit of the red subdwarf binary fraction of similar to 10 per cent. We find that the binary fraction goes down with decreasing masses and metallicities of red subdwarfs. A spectroscopic esdK7 subdwarf + white dwarf binary candidate is also reported. 30 new M subdwarfs have spectral type of >= M6 in our sample. We also derive relationships between spectral types and absolute magnitudes in the optical and near-infrared for M and L subdwarfs, and we present an M subdwarf sample with measured U, V, W space velocities.Peer reviewe
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