From "best practice" to "best fit": a framework for designing and analyzing pluralistic agricultural advisory services worldwide

"The paper develops a framework for the design and analysis of pluralistic agricultural advisory services and reviews research methods from different disciplines that can be used when applying the framework. Agricultural advisory services are defined in the paper as the entire set of organizations that support and facilitate people engaged in agricultural production to solve problems and to obtain information, skills and technologies to improve their livelihoods and well-being... To classify pluralistic agricultural advisory services, the paper distinguishes between organizations from the public, the private and the third sector that can be involved in (a) providing and (b) financing of agricultural advisory services. The framework for analyzing pluralistic agricultural advisory services presented in the paper addresses the need for analytical approaches that help policy-makers to identify those reform options that best fit country-specific frame conditions. Thus, the paper supports a shift from a “one-size-fits-all” to a “best fit” approach in the reform of public services... Based on a review of the literature, the paper presents a variety of quantitative and qualitative methodological approaches derived from different disciplines that can be applied when using the framework in empirical research projects. The disciplines include agricultural and institutional economics, communication theory, adult education, and public administration and management. The paper intends to inform researchers as well as practitioners, policy-makers and development partners who are interested in supporting evidence-based reform of agricultural advisory services. from Authors' AbstractAgricultural extension work, Pro-poor growth, Capacity strengthening,

Open for business: Pathways to strengthen CGIARs responsible private sector engagement

CGIAR has considerable experience with private sector engagement in the context of its mission to create sustainable and resilient food, land and water systems, and there is continuing interest and dialogue on this theme within CGIAR and the international development community more generally. The on-going CGIAR reform provides an opportunity to capture those experiences and harmonize strategies under the new structure, as has been acknowledged in the new 'CGIAR 2030 Research and Innovation Strategy'. Commissioned by the NL-CGIAR Strategic Partnership, this report aims to identify, discuss and evaluate pathways for strengthening collaboration between CGIAR and the private sector to stimulate innovation and the scaling of these innovations in food, land and water systems. The objective is to advance private sector engagement in the CGIAR, based on transparent CGIAR system-wide mechanisms and processes

Single-Atom Resolved Fluorescence Imaging of an Atomic Mott Insulator

The reliable detection of single quantum particles has revolutionized the field of quantum optics and quantum information processing. For several years, researchers have aspired to extend such detection possibilities to larger scale strongly correlated quantum systems, in order to record in-situ images of a quantum fluid in which each underlying quantum particle is detected. Here we report on fluorescence imaging of strongly interacting bosonic Mott insulators in an optical lattice with single-atom and single-site resolution. From our images, we fully reconstruct the atom distribution on the lattice and identify individual excitations with high fidelity. A comparison of the radial density and variance distributions with theory provides a precise in-situ temperature and entropy measurement from single images. We observe Mott-insulating plateaus with near zero entropy and clearly resolve the high entropy rings separating them although their width is of the order of only a single lattice site. Furthermore, we show how a Mott insulator melts for increasing temperatures due to a proliferation of local defects. Our experiments open a new avenue for the manipulation and analysis of strongly interacting quantum gases on a lattice, as well as for quantum information processing with ultracold atoms. Using the high spatial resolution, it is now possible to directly address individual lattice sites. One could, e.g., introduce local perturbations or access regions of high entropy, a crucial requirement for the implementation of novel cooling schemes for atoms on a lattice

RAAIS: Rapid Appraisal of Agricultural Innovation Systems (Part I). A diagnostic tool for integrated analysis of complex problems and innovation capacity

This paper introduces Rapid Appraisal of Agricultural Innovation Systems (RAAIS). RAAIS is a diagnostic tool that can guide the analysis of complex agricultural problems and innovation capacity of the agricultural system in which the complex agricultural problem is embedded. RAAIS focuses on the integrated analysis of different dimensions of problems (e.g. biophysical, technological, socio-cultural, economic, institutional and political), interactions across different levels (e.g. national, regional, local), and the constraints and interests of different stakeholder groups (farmers, government, researchers, etc.). Innovation capacity in the agricultural system is studied by analysing (1) constraints within the institutional, sectoral and technological subsystems of the agricultural system, and (2) the existence and performance of the agricultural innovation support system. RAAIS combines multiple qualitative and quantitative methods, and insider (stakeholders) and outsider (researchers) analyses which allow for critical triangulation and validation of the gathered data. Such an analysis can provide specific entry points for innovations to address the complex agricultural problem under study, and generic entry points for innovation related to strengthening the innovation capacity of agricultural system and the functioning of the agricultural innovation support system. The application of RAAIS to analyse parasitic weed problems in the rice sector, conducted in Tanzania and Benin, demonstrates the potential of the diagnostic tool and provides recommendations for its further development and use

Differences in Candidate Gene Association between European Ancestry and African American Asthmatic Children

Candidate gene case-control studies have identified several single nucleotide polymorphisms (SNPs) that are associated with asthma susceptibility. Most of these studies have been restricted to evaluations of specific SNPs within a single gene and within populations from European ancestry. Recently, there is increasing interest in understanding racial differences in genetic risk associated with childhood asthma. Our aim was to compare association patterns of asthma candidate genes between children of European and African ancestry.Using a custom-designed Illumina SNP array, we genotyped 1,485 children within the Greater Cincinnati Pediatric Clinic Repository and Cincinnati Genomic Control Cohort for 259 SNPs in 28 genes and evaluated their associations with asthma. We identified 14 SNPs located in 6 genes that were significantly associated (p-values <0.05) with childhood asthma in African Americans. Among Caucasians, 13 SNPs in 5 genes were associated with childhood asthma. Two SNPs in IL4 were associated with asthma in both races (p-values <0.05). Gene-gene interaction studies identified race specific sets of genes that best discriminate between asthmatic children and non-allergic controls.We identified IL4 as having a role in asthma susceptibility in both African American and Caucasian children. However, while IL4 SNPs were associated with asthma in asthmatic children with European and African ancestry, the relative contributions of the most replicated asthma-associated SNPs varied by ancestry. These data provides valuable insights into the pathways that may predispose to asthma in individuals with European vs. African ancestry

Systems approaches to innovation in crop protection. A systematic literature review

The objective of this paper is to explore the extent to which systems approaches to innovation are reflected in the crop protection literature and how such approaches are used. A systematic literature review is conducted to study the relation between crop protection and systems approaches to innovation in 107 publications. The analysis of the crop protection literature demonstrates that only a small fraction is systems-oriented as compared to the bulk of publications with a technology-oriented approach. The analysis of agricultural innovations systems literature shows that, although crop protection is addressed, the potential of this systems approach remains largely unexplored for crop protection innovation. A large share of the publications included in this review focus on cropping or farming ‘systems’ while ‘innovation’ often equals the development, transfer, adoption and diffusion of crop protection technologies at farm level. There is relatively little attention for the institutional and political dimensions of crop protection and the interactions between farm, regional and national levels in crop protection systems. The traditional division of roles and responsibilities of researchers as innovators, extension personnel as disseminators, and farmers as end-users, is challenged only to a limited extent. The majority of publications discusses ways to optimise existing features of crop protection systems, without exploring more structural transformations that may be required to enhance the resilience of crop protection systems

Identification of Copy Number Variants Defining Genomic Differences among Major Human Groups

BACKGROUND:Understanding the genetic contribution to phenotype variation of human groups is necessary to elucidate differences in disease predisposition and response to pharmaceutical treatments in different human populations. METHODOLOGY/PRINCIPAL FINDINGS:We have investigated the genome-wide profile of structural variation on pooled samples from the three populations studied in the HapMap project by comparative genome hybridization (CGH) in different array platforms. We have identified and experimentally validated 33 genomic loci that show significant copy number differences from one population to the other. Interestingly, we found an enrichment of genes related to environment adaptation (immune response, lipid metabolism and extracellular space) within these regions and the study of expression data revealed that more than half of the copy number variants (CNVs) translate into gene-expression differences among populations, suggesting that they could have functional consequences. In addition, the identification of single nucleotide polymorphisms (SNPs) that are in linkage disequilibrium with the copy number alleles allowed us to detect evidences of population differentiation and recent selection at the nucleotide variation level. CONCLUSIONS:Overall, our results provide a comprehensive view of relevant copy number changes that might play a role in phenotypic differences among major human populations, and generate a list of interesting candidates for future studies

Local governance systems and smallholder cooperatives in Ethiopia

There is ample evidence to suggest that improving the on-farm productivity of small-scale farmers and integrating them into commercial markets is a promising strategy for alleviating poverty and leveraging agriculture as an engine of wider economic growth. Yet, persistent market failures in large parts of sub-Saharan Africa have limited the impact of this strategy. As a result, there is increasing interest in the study of state and community failures -- the underlying rural governance issues -- that affect small-scale farmers. This paper contributes to this area of inquiry by examining the role of farmers' cooperatives in local governance systems in Ethiopia. By drawing on both qualitative and quantitative data sources, the paper offers new insights into the potential role of rural governance systems in national development strategies, the interactions between formal and informal rural governance systems, and possible avenues through which farmers' cooperatives can contribute to improving rural governance and national development.rural producer organisations, farmer cooperatives, rural governance, Ethiopia, local governance, smallholder cooperatives, poverty reduction, on-farm productivity, small-scale farmers, national development strategy, small farms,

Open for business – Pathways to strengthen CGIAR’s responsible private sector engagement

CGIAR has considerable experience with private sector engagement in the context of its mission to create sustainable and resilient food, land and water systems, and there is continuing interest and dialogue on this theme within CGIAR and the international development community more generally. The on-going CGIAR reform provides an opportunity to capture those experiences and harmonize strategies under the new structure, as has been acknowledged in the new 'CGIAR 2030 Research and Innovation Strategy'. Commissioned by the NL-CGIAR Strategic Partnership, this report aims to identify, discuss and evaluate pathways for strengthening collaboration between CGIAR and the private sector to stimulate innovation and the scaling of these innovations in food, land and water systems. The objective is to advance private sector engagement in the CGIAR, based on transparent CGIAR system-wide mechanisms and processes