817 research outputs found
Physical properties and small-scale structure of the Lyman-alpha forest: Inversion of the HE 1122-1628 UVES spectrum
We study the physical properties of the Lyman-alpha forest by applying the
inversion method described by Pichon et al. (2001) to the high resolution and
high S/N ratio spectrum of the z_em=2.40 quasar HE 1122-1628 obtained during
Science Verification of UVES at the VLT. We compare the column densities
obtained with the new fitting procedure with those derived using standard Voigt
profile methods. The agreement is good and gives confidence in the new
description of the Lyman-alpha forest as a continuous field as derived from our
method. We show that the observed number density of lines with logN>13 and 14
is, respectively, 50 and 250 per unit redshift at z~2. We study the physical
state of the gas, neglecting peculiar velocities, assuming a relation between
the overdensity and the temperature. T=Tbar * rho^(2beta). There is an
intrinsic degeneracy between the parameters beta and Tbar. We demonstrate that,
at a fixed beta, the temperature at mean density, Tbar, can be uniquely
extracted however. While applying the method to HE 1122-1628, we conclude that
for 0.2<beta<0.3, 6000<Tbar<15000 K at z~2. We investigate the small scale
structure of strong absorption lines using the information derived from the
Lyman-beta, Lyman-gamma and Civ profiles. Introducing the Lyman-beta line in
the fit allows us to reconstruct the density field up to rho~10 instead of 5
for the Lyman-alpha line only. There may be small velocity shifts ~10km.s^{-1}
between the peaks in the Civ and Hi density profiles. Although the statistics
is small, it seems that Civ/Hi and n_HI are anti-correlated. This could be a
consequence of the high sensitivity of the Civ/Hi ratio to temperature. The
presence of associated Ovi absorption, with similar profile, confirms that the
gas is photo-ionized and at a temperature of T~10^5 K.Comment: 15 pages, 21 figures, accepted for publication in A&A. Quoted results
from other papers in section 4.2 have been modifie
Quantitative analysis of soft-bottom molluscs in the Bellingshausen Sea and around Peter I Island
Macrobenthic soft-bottom molluscs were sampled in 30 stations located in the Bellingshausen Sea at depths ranging from 90 to 3304 m. The samples were collected using a quantitative grab box-corer during the cruises BENTART 03, from 24 January to 3 March 2003, and BENTART 06, from 2 January to 16 February 2006. Molluscs represent 1074 specimens belonging to 62 species of Polyplacophora, Gastropoda, Bivalvia and Scaphopoda. The bivalve Cyamiocardium denticulatum was the most abundant species (448 specimens). The abundance per station varied between 1 and 446 specimens. The Shannon–Wiener diversity index ranged between one specimen and 2.36, the Pielou evenness index ranged between 0.00 and 1 and species richness ranged from 1 to 14 species. Diversity showed great variations at different stations. After multivariate analysis (cluster analysis and nonmetrical multidimensional scaling) based on Bray–Curtis similarities, we were able to separate two principal clusters. The first cluster groups together species from shallower bottoms near Peter I Island and the Antarctic Peninsula, and the second cluster groups together species from deeper bottoms in the Bellingshausen Sea. The combination of environmental variables with the highest correlations with faunistic data was that of depth and coarse sand at the surface.Publicado
Physical mapping integrated with syntenic analysis to characterize the gene space of the long arm of wheat chromosome 1A
Background: Bread wheat (Triticum aestivum L.) is one of the most important crops worldwide and its production faces pressing challenges, the solution of which demands genome information. However, the large, highly repetitive hexaploid wheat genome has been considered intractable to standard sequencing approaches. Therefore the International Wheat Genome Sequencing Consortium (IWGSC) proposes to map and sequence the genome on a chromosome-by-chromosome basis.
Methodology/Principal Findings: We have constructed a physical map of the long arm of bread wheat chromosome 1A using chromosome-specific BAC libraries by High Information Content Fingerprinting (HICF). Two alternative methods (FPC and LTC) were used to assemble the fingerprints into a high-resolution physical map of the chromosome arm. A total of 365 molecular markers were added to the map, in addition to 1122 putative unique transcripts that were identified by microarray hybridization. The final map consists of 1180 FPC based or 583 LTC based contigs. Conclusions/Significance: The physical map presented here marks an important step forward in mapping of hexaploid bread wheat. The map is orders of magnitude more detailed than previously available maps of this chromosome, and the assignment of over a thousand putative expressed gene sequences to specific map locations will greatly assist future functional studies. This map will be an essential tool for future sequencing of and positional cloning within chromosome 1A
Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions.
This review focuses on the biologic importance of the vitamin D binding protein (DBP) with emphasis on its regulation of total and free vitamin D metabolite levels in various clinical conditions. Nearly all DBP is produced in the liver, where its regulation is influenced by estrogen, glucocorticoids and inflammatory cytokines but not by vitamin D itself. DBP is the most polymorphic protein known, and different DBP alleles can have substantial impact on its biologic functions. The three most common alleles-Gc1f, Gc1s, Gc2-differ in their affinity with the vitamin D metabolites and have been variably associated with a number of clinical conditions. Although DBP has a number of biologic functions independent of vitamin D, its major biologic function is that of regulating circulating free and total levels of vitamin D metabolites. 25 hydroxyvitamin D (25(OH)D) is the best studied form of vitamin D as it provides the best measure of vitamin D status. In a normal non-pregnant individual, approximately 0.03% of 25(OH)D is free; 85% is bound to DBP, 15% is bound to albumin. The free hormone hypothesis postulates that only free 25(OH)D can enter cells. This hypothesis is supported by the observation that mice lacking DBP, and therefore with essentially undetectable 25(OH)D levels, do not show signs of vitamin D deficiency unless put on a vitamin D deficient diet. Similar observations have recently been described in a family with a DBP mutation. This hypothesis also applies to other protein bound lipophilic hormones including glucocorticoids, sex steroids, and thyroid hormone. However, tissues expressing the megalin/cubilin complex, such as the kidney, have the capability of taking up 25(OH)D still bound to DBP, but most tissues rely on the free level. Attempts to calculate the free level using affinity constants generated in a normal individual along with measurement of DBP and total 25(OH)D have not accurately reflected directly measured free levels in a number of clinical conditions. In this review, we examine the impact of different clinical conditions as well as different DBP alleles on the relationship between total and free 25(OH)D, using only data in which the free 25(OH)D level was directly measured. The major conclusion is that a number of clinical conditions alter this relationship, raising the question whether measuring just total 25(OH)D might be misleading regarding the assessment of vitamin D status, and such assessment might be improved by measuring free 25(OH)D instead of or in addition to total 25(OH)D
Axion searches with the EDELWEISS-II experiment
We present new constraints on the couplings of axions and more generic
axion-like particles using data from the EDELWEISS-II experiment. The EDELWEISS
experiment, located at the Underground Laboratory of Modane, primarily aims at
the direct detection of WIMPs using germanium bolometers. It is also sensitive
to the low-energy electron recoils that would be induced by solar or dark
matter axions. Using a total exposure of up to 448 kg.d, we searched for
axion-induced electron recoils down to 2.5 keV within four scenarios involving
different hypotheses on the origin and couplings of axions. We set a 95% CL
limit on the coupling to photons GeV in
a mass range not fully covered by axion helioscopes. We also constrain the
coupling to electrons, , similar to the more
indirect solar neutrino bound. Finally we place a limit on , where is the
effective axion-nucleon coupling for Fe. Combining these results we
fully exclude the mass range keV for DFSZ axions and
keV for KSVZ axions
Recommended from our members
All-sky search for short gravitational-wave bursts in the second Advanced LIGO and Advanced Virgo run
We present the results of a search for short-duration gravitational-wave transients in the data from the second observing run of Advanced LIGO and Advanced Virgo. We search for gravitational-wave transients with a duration of milliseconds to approximately one second in the 32-4096 Hz frequency band with minimal assumptions about the signal properties, thus targeting a wide variety of sources. We also perform a matched-filter search for gravitational-wave transients from cosmic string cusps for which the waveform is well modeled. The unmodeled search detected gravitational waves from several binary black hole mergers which have been identified by previous analyses. No other significant events have been found by either the unmodeled search or the cosmic string search. We thus present the search sensitivities for a variety of signal waveforms and report upper limits on the source rate density as a function of the characteristic frequency of the signal. These upper limits are a factor of 3 lower than the first observing run, with a 50% detection probability for gravitational-wave emissions with energies of ∼10-9 Mc2 at 153 Hz. For the search dedicated to cosmic string cusps we consider several loop distribution models, and present updated constraints from the same search done in the first observing run
Recommended from our members
Search for gravitational waves from Scorpius X-1 in the second Advanced LIGO observing run with an improved hidden Markov model
We present results from a semicoherent search for continuous gravitational
waves from the low-mass X-ray binary Scorpius X-1, using a hidden Markov model
(HMM) to track spin wandering. This search improves on previous HMM-based
searches of LIGO data by using an improved frequency domain matched filter, the
-statistic, and by analysing data from Advanced LIGO's second
observing run. In the frequency range searched, from to
, we find no evidence of gravitational radiation. At
, the most sensitive search frequency, we report an upper
limit on gravitational wave strain (at 95\% confidence) of when marginalising over source inclination angle. This is the
most sensitive search for Scorpius X-1, to date, that is specifically designed
to be robust in the presence of spin wandering
- …