Effect of dietary antioxidant supplementation on rabbit performance, meat quality and oxidative stability of muscles

[EN] The aim of this study was to cast light on the effects of EconomasE™ (EcoE), a patented pre-mixture of nutritional additives consisting mainly of organic selenium (0.15 or 0.30 mg/kg feed; Se) combined with vitamin C (5 and 10 mg/kg feed; VC), compared to DL-α-tocopherol acetate (100 or 200 mg/kg feed; VE) dietary supplementation on rabbit performance and meat quality. In fact, the role of Se supplementation in the rabbit diet has not yet been elucidated in the literature and, more specifically, there are no studies on the possible synergistic action between organic Se compared with VE on lipids, fatty acids (FA) and the oxidative stability of two glycolytic muscles, longissimus lumborum (LL) and biceps femoris (BF). Two hundred and seventy New Zealand White rabbits were divided into five dietary groups of 54 rabbits each: 1) control (basal diet = BD; CTRL); 2) VE100 (BD + VE100 mg/kg); 3) VE200 (BD + VE200 mg/kg); 4) EcoE100 (BD + EcoE100 mg/kg); and 5) EcoE200 (BD + EcoE200 mg/kg). Neither of the antioxidant treatments affected growth performance, carcass traits or meat characteristics. Lipid and fatty acid contents were similar in LL and BF and not influenced by the dietary treatment. Meat oxidative stability was strongly improved by both antioxidants. These findings indicate that both EcoE and VE greatly improved the oxidative stability of LL and BF muscles at the dosage rates which, from an economic point of view, would normally be included in the formulation of feeds for rabbits.This study is part of a multidisciplinary research project funded by the Department of Veterinary Medical Science (University of Bologna, Italy). The authors thank Martini Group Spa (Budrio di Longiano, FC, Italy) who provided animals and feeds, and Alltech (Casalecchio di Reno, BO, Italy) who supplied the EcoE.Minardi, P.; Mordenti, A.; Badiani, A.; Pirini, M.; Trombetti, F.; Albonetti, S. (2020). Effect of dietary antioxidant supplementation on rabbit performance, meat quality and oxidative stability of muscles. World Rabbit Science. 28(3):145-159. https://doi.org/10.4995/wrs.2020.12273OJS145159283Abdel-Khalek A.M. 2013. Supplemental antioxidants in rabbit nutrition: A review. Livest. Sci., 158: 95-105. https://doi.org/10.1016/j.livsci.2013.10.019Alasnier C., Gandemer G. 1998. Fatty acid and aldehyde composition of individual phospholipid classes of rabbit skeletal muscles is related to the metabolic type of the fiber. Meat Sci., 48: 225-235. https://doi.org/10.1016/S0309-1740(97)00096-XAlbonetti S., Minardi P., Trombetti F., Savigni F., Mordenti A.L., Baranzoni G.M., Trivisano C., Greco F.P., Badiani A. 2017. In vivo and in vitro effects of selected antioxidants on rabbit meat microbiota. Meat Sci., 123: 88-96. https://doi.org/10.1016/j.meatsci.2016.09.004AMSA 1995. Research guidelines for cookery, sensory evaluation and instrumental tenderness measurements of fresh meat. Chicago, Illinois, USA: American Meat Science Association in cooperation with National Live Stock and Meat Board.AOAC 2000. Official methods of analysis. Official Methods of Analysis of AOAC, 17th ed. Gaithersburg, MD, USA.AOAC 2006. Official methods of analysis. Official Methods of Analysis of AOAC, 18th ed. Gaithersburg, MD, USA.Blasco A., Ouhayoun J. 1993. Harmonisation of criteria and terminology in rabbit meat research. Revised proposal. World Rabbit Sci., 4: 93-99. https://doi.org/10.4995/wrs.1996.278Bligh E.G., Dyer W.J. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol., 37: 911-917. https://doi.org/10.1139/o59-099Castellini C., Dal Bosco A., Bernardini M. 2001. Improvement of lipid stability of rabbit meat by vitamin E and C administration. J. Sci. Food Agric., 81: 46-53. https://doi.org/10.1002/1097-0010(20010101)81:13.0.CO;2-4Chauhan S.S., Liu F., Leury B.J., Cottrell J.J., Celi P., Dunshea F.R. 2016. Functionality and genomics of selenium and vitamin E supplementation in ruminants. Anim. Prod. Sci., 56: 1285-1298. https://doi.org/10.1071/AN15263CIE (Commission Internationale de l'Eclairage). 1976. Official recommendations on uniform colour spaces, colour differences equations and metric colour terms. Suppl. 2 to CIE, publications 15. Paris, France. https://doi.org/10.1002/j.1520-6378.1977.tb00102.xCorino C., Lo Fiego D.P., Macchioni P., Pastorelli G., Di Giancamillo A., Domeneghini C., Rossi R. 2007. Influence of dietary conjugated linoleic acids and vitamin E on meat quality, and adipose tissue in rabbits. Meat Sci., 76: 19-28. https://doi.org/10.1016/j.meatsci.2006.10.007Cullere M., Dalle Zotte A. 2018. Rabbit meat production and consumption: State of knowledge and future perspectives. Meat Sci., 143: 137-146. https://doi.org/10.1016/j.meatsci.2018.04.029Dalle Zotte A., Cullere M., Rémignon H., Alberghini L., Paci G. 2016. Meat physical quality and muscle fiber properties of rabbit meat as affected by the sire breed, season, parity order and gender in an organic production system. World Rabbit Sci., 24: 145-154. https://doi.org/10.4995/wrs.2016.4300Dalle Zotte A., Rémignon H., Ouhayoun J. 2005. Effect of feed rationing during post-weaning growth on meat quality, muscle energy metabolism and fiber properties of Biceps femoris muscle in the rabbit. Meat Sci., 70: 301-306. https://doi.org/10.1016/j.meatsci.2005.01.016Dalle Zotte A., Szendrő Z. 2011. The role of rabbit meat as functional food. Meat Sci., 88: 319-331. https://doi.org/10.1016/j.meatsci.2011.02.017Dokoupilová A., Marounek M., Skrivanova V., Brezina P. 2007. Selenium content in tissues and meat quality in rabbits fed selenium yeast. Czech. J. Anim. Sci., 52: 165-169. https://doi.org/10.17221/2319-CJASEbeid T.A., Zeweil H.S., Basyony M.M., Dosoky W.M., Badry H. 2013. Fortification of rabbit diets with vitamin E or selenium affects growth performance, lipid peroxidation, oxidative status and immune response in growing rabbits. Livest. Sci., 155: 323-331. https://doi.org/10.1016/j.livsci.2013.05.011EFSA AHAW Panel 2020. Scientific Opinion on the health and welfare of rabbits farmed in different production systems. EFSA Journal, 18: 5944. https://doi.org/10.2903/j.efsa.2020.5944Eiben Cs., Végi B., Virág Gy., Gódor-Surmann K., Kustos K., Maró A., Odermatt M., Zsédely E., Tóth T., Schmidt J., Fébel H. 2011. Effect of level and source of vitamin E addition of a diet enriched with sunflower and linseed oils on growth and slaughter traits of rabbits. Livest. Sci., 139: 196-205. https://doi.org/10.1016/j.livsci.2011.01.010Erdèlyi M., Virág G., Mézes M. 2000. Effect of supranutritional additive selenium supply on the tissue selenium concentration and the activity of glutathione peroxidase enzyme in rabbit. World Rabbit Sci., 8: 183-191.Erickson M.C. 1992. Variation of lipid and tocopherol composition in three strains of channel catfish (Ictalurus punctatus). J. Sci. Food Agric., 59: 529-536. https://doi.org/10.1002/jsfa.2740590416European Communities: Council Regulation (EC) 2011. 1169/2011 on the Provision of Food Information to Consumers. Available at: http://eur-lex.europa.eu/legal-content/EN/TXT/HTML/?uri=CELEX:32011R1169&from=EN. Accessed April 2017.Giaretta E., Mordenti A., Palmonari A., Brogna N., Canestrari G., Belloni P., Cavallini D., Mammi L., Cabbri R., Formigoni A. 2019. NIRs calibration models for chemical composition and fatty acid families of raw and freeze-dried beef: A comparison. J. Food Compost. Anal., 83: 103257. https://doi.org/10.1016/j.jfca.2019.103257Gondret F., Lebas F., Bonneau M. 2000. Restricted feed intake during fattening reduces intramuscular lipid deposition without modifying muscle fiber characteristics in rabbits. J. Nutr., 130: 228-233. https://doi.org/10.1093/jn/130.2.228Honikel K.O. 1998. Reference methods for the assessment of physical characteristics of meat. Meat Sci., 49: 447-457. https://doi.org/10.1016/S0309-1740(98)00034-5Ichihara K., Shibahara A., Yamamoto K., Nakayama T. 1996. An improved method for rapid analysis of the fatty acids of glycerolipids. Lipids, 31: 535-539. https://doi.org/10.1007/BF02522648ISO 1998. Animal feeding stuffs, animal products and faeces or urine. Determination of gross calorific value - Bomb calorimetric method (Reference number 9831). Available at: https://www.iso.org/standard/17702.html. Accessed July 2017.Kouba M., Benatmane F., Blochet J.E., Mourot J. 2008. Effect of a linseed diet on lipid oxidation, fatty acid composition of muscle, perirenal fat, and raw and cooked rabbit meat. Meat Sci., 80: 829-834. https://doi.org/10.1016/j.meatsci.2008.03.029Lee Y.H., Layman D.K., Bell R.R. 1979. Selenium-dependent and non-selenium-dependent glutathione peroxidase activity in rabbit tissue. Nutr. Rep. Int., 20: 573-578.Lo Fiego D.P., Santoro P., Macchioni P., Mazzoni D., Piattoni F., Tassone F., De Leonibus E. 2004. The effect of dietary supplementation of vitamins C and E on the α-tocopherol content of muscles, liver and kidney, on the stability of lipids, and on certain meat quality parameters of the Longissimus dorsi of rabbits. Meat Sci., 67: 319-327. https://doi.org/10.1016/j.meatsci.2003.11.004Lopez-Bote C.J., Rey A.I., Sanz M., Gray J.I., Buckley D.J. 1997. Dietary vegetable oils and α-tocopherol reduce lipid oxidation in rabbit muscle. J. Nutr., 127: 1176-1182. https://doi.org/10.1093/jn/127.6.1176Maraschiello C., Sárraga C., García Regueiro J.A. 1999. Glutathione peroxidase activity, TBARS, and α-Tocopherol in meat from chickens fed different diets. J. Agr. Food Chem., 47: 867-872. https://doi.org/10.1021/jf980824oMarounek M., Dokoupilová A., Volek Z., Hoza I. 2009. Quality of meat and selenium content in tissues of rabbits fed diets supplemented with sodium selenite, selenized yeast and selenized algae. World Rabbit Sci., 17: 207-212. https://doi.org/10.4995/wrs.2009.645Martillotti F., Antongiovanni M., Rizzi L., Santi E., Bittante G. 1987. Metodi di analisi per la valutazione degli alimenti d'impiego zootecnico. Quaderni Metodologici, 8, CNR-IPRA, Roma.Mateos G.G., Rebollar P.G., de Blas C. 2010. Minerals, vitamins and additives. In: C. DE BLAS and J. WISEMAN (Eds.) Nutrition of the rabbit. 2nd Edition. CABI Publishing, New York: USA, 119-150. https://doi.org/10.1079/9781845936693.0222Matics Z., Cullere M., Szín M., Gerencsér Zs., Szabó A., Fébel H., Odermatt M., Radnai I., Dalle Zotte A., Szendrő Zs. 2017. Effect of a dietary supplementation with linseed oil and selenium to growing rabbits on their productive performances, carcass traits and fresh and cooked meat quality. J. Anim. Physiol. Anim. Nutr., 101: 685-693. https://doi.org/10.1111/jpn.12589Mattioli S., Cardinali R., Balzano M., Pacetti D., Castellini C., Dal Bosco A., Frega N.G. 2017. Influence of dietary supplementation with prebiotic, oregano extract, and vitamin E on fatty acid profile and oxidative status of rabbit meat. J. Food Qual., Article ID 3015120, 1-9. https://doi.org/10.1155/2017/3015120McLellan M.R., Lind L.R., Kime R.W. 1995. Hue angle determinations and statistical analysis for multiquadrant hunter L,a,b data. J. Food Qual., 18: 235-240. https://doi.org/10.1111/j.1745-4557.1995.tb00377.xMézes M., Balogh K. 2009. Mycotoxins in rabbit feed: a review. World Rabbit Sci., 17: 53-62.Midttun Ø., Ueland P.M. 2011. Determination of vitamins A, D and E in a small volume of human plasma by a high-throughput method based on liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Sp., 25: 1942-1948. https://doi.org/10.1002/rcm.5073Montero-Vicente L., Escribá-Pérez C., Baviera-Puig A., Buitrago-Vera J. 2018. Analysis of the commercial value of rabbit meat based on positioning of the different types of fresh meat. Span. J. Agric. Res., 16: e0110. https://doi.org/10.5424/sjar/2018163-13407Mordenti A.L., Sardi L., Bonaldo A., Pizzamiglio V., Brogna N., Cipollini I., Tassinari M., Zaghini G. 2010. Influence of marine algae (Schizochytrium spp.) dietary supplementation on doe performance and progeny meat quality. Livest. Sci., 128: 179-184. https://doi.org/10.1016/j.livsci.2009.12.003Müller A.S., Pallauf J., Most E. 2002. Parameters of dietary selenium and vitamin E deficiency in growing rabbits. J. Trace Elem. Med. Biol., 16: 47-55. https://doi.org/10.1016/S0946-672X(02)80008-6Nambapana N.M.N., Samarasinghe K., Vidanarachchi J.K. 2015. The effect of EconomasE® as a vitamin E replacer on performance, meat quality and organ weights of broiler birds. Trop. Agric. Res., 27: 27-38. http://doi.org/10.4038/tar.v27i1.8151Oriani G., Corino C., Pastorelli G., Pantaleo L., Ritieni A., Salvatori G. 2001. Oxidative status of plasma and muscle in rabbits supplemented with dietary vitamin E. J. Nutr. Biochem., 12: 138-143. https://doi.org/10.1016/S0955-2863(00)00132-7Papadomichelakis G., Zoidis E., Pappas A.C., Mountzouris K.C., Fegeros K. 2017. Effects of increasing dietary organic selenium levels on meat fatty acid composition and oxidative stability in growing rabbits. Meat Sci., 131: 132-138. https://doi.org/10.1016/j.meatsci.2017.05.006Peiretti P.G., Gasco L., Brugiapaglia A., Gai F. 2011. Effects of perilla (Perilla frutescens L.) seeds supplementation on performance, carcass characteristics, meat quality and fatty acid composition of rabbits. Livest Sci., 138: 118-124. https://doi.org/10.1016/j.livsci.2010.12.007Petrescu D.C., Petrescu-Mag R.M. 2018. Consumer behaviour related to rabbit meat as fucntional food. World Rabbit Sci., 26: 321-333. https://doi.org/10.4995/wrs.2018.10435Pirini M., Manuzzi M.P., Pagliarani A., Trombetti F., Borgatti A.R., Ventrella V. 2007. Changes in fatty acid composition of Mytilus galloprovincialis (Lmk) fed on microalgal and wheat germ diets. Comp. Biochem. Physiol. Part B, 147: 616-626. https://doi.org/10.1016/j.cbpb.2007.04.003Ulbricht T., Southgate D. 1991. Coronary heart disease: seven dietary factors. Lancet, 338: 985-992. https://doi.org/10.1016/0140-6736(91)91846-MUnited States Environmental Protection Agency (U.S. EPA) 1986. Test methods for evaluating solid waste, 3rd Edition, Vol. 1A. SW-846. Washington, DC.Van Soest P.J., Robertson J.B., Lewis B.A. 1991. Methods for dietary fiber, neutral detergent fiber, and non-starch polysaccharides in relation to animal nutrition. J. Dairy Sci., 74: 3583-3597. https://doi.org/10.3168/jds.S0022-0302(91)78551-2Xiao R., Power R.F., Mallonee D., Crowdus C., Brennan K. M., Ao T., Pierce J.L., Dawson K.A. 2011. A comparative transcriptomic study of vitamin E and an algae-based antioxidant as antioxidative agents: Investigation of replacing vitamin E with the algae-based antioxidant in broiler diets. Poultry Sci., 90: 136-146. https://doi.org/10.3382/ps.2010-01018Zhang Y., Zhu S., Wang X., Wang C., Li F. 2011. The effect of dietary selenium levels on growth performance, antioxidant capacity and glutathione peroxidase 1 (GSHPx1) mRNA expression in growing meat rabbits. Anim. Feed Sci. Tech., 169: 259-264. https://doi.org/10.1016/j.anifeedsci.2011.07.00

Lipase catalysed oxidations in a sugar-derived natural deep eutectic solvent

Chemoenzymatic oxidations involving the CAL-B/H2O2 system was developed in a sugar derived Natural Deep Eutectic Solvent (NaDES) composed by a mixture of glucose, fructose and sucrose. Good to excellent conversions of substrates like cyclooctene, limonene, oleic acid and stilbene to their corresponding epoxides, cyclohexanone to its corresponding lactone and 2-phenylacetophenone to its corresponding ester, demonstrate the viability of the sugar NaDES as a reaction medium for epoxidation and Baeyer-Villiger oxidation

Thoracic myopericytoma in an older adult, rare but possible: A case report

Myopericytoma is a rare tumor generally arising from skin and soft tissues of extremities, trunk, head, and neck regions, rarely from visceral sites. An intrathoracic visceral localization may carry a broad differential diagnosis including primary lung, pleura and chest wall lesions, or metastatic lesions. To date, any radiological features have been recognized and diagnosis of myopericytoma with intrathoracic localization remains still challenging. Here, we describe the case of a subpleural lesion incidentally diagnosed in an older adult affected by gastric cancer. Radiological features did not allow a differential diagnosis between a benign lesion, a primary tumor, or a metastasis. After resection, the histological examination showed histopathological features congruent with the diagnosis of myopericytoma. This unusual presentation reflects the need to share clinical, radiological, and histopathological data about this uncommon but frequently misdiagnosed disease

Paratesticular Mesenchymal Malignancies: A Single-Center Case Series, Clinical Management, and Review of Literature

Background: Primary soft tissue sarcomas arising from the male urinary and genital tract are rare tumors, only accounting for 1% to 2% of all malignancies of the genitourinary tract. Clinical management of advanced disease is lacking in standardized recommendations due to the rarity of the disease. To date, complete and extensive surgery represents the only curative and standardized approach for localized disease, while the impact of retroperitoneal lymphadenectomy and adjuvant treatments on clinical outcomes are still unclear. Similarly, a standardized systemic treatment for advanced metastatic disease is still missing. Cases Presentation: Four out of 274 patients have been identified in our sarcoma population. The mean age was 54 years (range = 45-73). The histotypes showed liposarcoma in 2 cases and leiomyosarcoma in the remaining 2 cases. In all 4 cases, the disease was localized at presentation, patients underwent complete surgery, and no adjuvant treatments were done. Three cases presented a recurrence of disease at a mean follow-up of 86 months (range = 60-106 months), more than 7 years. Two cases were treated with a second surgery and chemotherapy and 1 case only with chemotherapy. Discussion and Conclusions: Sharing data about clinical management of paratesticular mesenchymal tumors is a key issue due to the rarity of this tumor\u2019s subtype. In this article, we report the clinical history of 4 patients affected by paratesticular mesenchymal tumor. In particular, main issues of interest are the decision of postoperative treatment and systemic treatment at time of disease recurrence

Multigene panel testing increases the number of loci associated with gastric cancer predisposition

The main gene involved in gastric cancer (GC) predisposition is CDH1, the pathogenic variants of which are associated with diffuse-type gastric cancer (DGC) and lobular breast cancer (LBC). CDH1 only explains a fraction (10–50%) of patients suspected of DGC/LBC genetic predisposition. To identify novel susceptibility genes, thus improving the management of families at risk, we performed a multigene panel testing on selected patients. We searched for germline pathogenic variants in 94 cancer-related genes in 96 GC or LBC Italian patients with early-onset and/or family history of GC. We found CDH1 pathogenic variants in 10.4% of patients. In 11.5% of cases, we identified loss-of-function variants in BRCA1, BRCA2, PALB2, and ATM breast/ovarian cancer susceptibility genes, as well as in MSH2, PMS2, BMPR1A, PRF1, and BLM genes. In 78.1% of patients, we did not find any variants with clear-cut clinical significance; however, 37.3% of these cases harbored rare missense variants predicted to be damaging by bioinformatics tools. Multigene panel testing decreased the number of patients that would have otherwise remained genetically unexplained. Besides CDH1, our results demonstrated that GC pathogenic variants are distributed across a number of susceptibility genes and reinforced the emerging link between gastric and breast cancer predisposition.This research was supported by the Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, by the Italian Ministry of Education, University and Research (MIUR)—Dipartimenti di Eccellenza Program (2018–2022)—Department of Biology and Biotechnology L. Spallanzani, University of Pavia, and by the Dunia Beam Erasmus Mundus project (fellowship to R.A.K.)

Identification of a delta5-like fatty acyl desaturase from the cephalopod Octopus vulgaris (Cuvier 1797) involved in the biosynthesis of essential fatty acids

Long-chain polyunsaturated fatty acids (LC-PUFA) have been identified as essential compounds for common octopus (Octopus vulgaris), but precise dietary requirements have not been determined due in part to the inherent difficulties of performing feeding trials on paralarvae. Our objective is to establish the essential fatty acid (EFA) requirements for paralarval stages of the common octopus through characterisation of the enzymes of endogenous LC-PUFA biosynthetic pathways. In this study we isolated a cDNA with high homology to fatty acyl desaturases (Fad). Functional characterisation in recombinant yeast showed the octopus Fad exhibited ∆5 desaturation activity towards saturated and polyunsaturated fatty acyl substrates. Thus, it efficiently converted the yeast’s endogenous 16:0 and 18:0 to 16:1n-11 and 18:1n-13, respectively, and desaturated exogenously added PUFA substrates, 20:4n-3 and 20:3n-6, to 20:5n-3 (EPA) and 20:4n-6 (ARA), respectively. Although the ∆5 Fad enables common octopus to produce EPA and ARA, the low availability of its adequate substrates 20:4n-3 and 20:3n-6, either in the diet or by limited endogenous synthesis from C18 PUFA, might indicate that EPA and ARA are indeed EFA for this species. Interestingly, the octopus ∆5 Fad can also participate in the biosynthesis of non-methylene interrupted FA, PUFA that are generally uncommon in vertebrates but that have been found previously in marine invertebrates including molluscs, and now also confirmed to be present in specific tissues of common octopus

GrassPlot - a database of multi-scale plant diversity in Palaearctic grasslands

GrassPlot is a collaborative vegetation-plot database organised by the Eurasian Dry Grassland Group (EDGG) and listed in the Global Index of Vegetation-Plot Databases (GIVD ID EU-00-003). GrassPlot collects plot records (releves) from grasslands and other open habitats of the Palaearctic biogeographic realm. It focuses on precisely delimited plots of eight standard grain sizes (0.0001; 0.001;... 1,000 m(2)) and on nested-plot series with at least four different grain sizes. The usage of GrassPlot is regulated through Bylaws that intend to balance the interests of data contributors and data users. The current version (v. 1.00) contains data for approximately 170,000 plots of different sizes and 2,800 nested-plot series. The key components are richness data and metadata. However, most included datasets also encompass compositional data. About 14,000 plots have near-complete records of terricolous bryophytes and lichens in addition to vascular plants. At present, GrassPlot contains data from 36 countries throughout the Palaearctic, spread across elevational gradients and major grassland types. GrassPlot with its multi-scale and multi-taxon focus complements the larger international vegetationplot databases, such as the European Vegetation Archive (EVA) and the global database " sPlot". Its main aim is to facilitate studies on the scale-and taxon-dependency of biodiversity patterns and drivers along macroecological gradients. GrassPlot is a dynamic database and will expand through new data collection coordinated by the elected Governing Board. We invite researchers with suitable data to join GrassPlot. Researchers with project ideas addressable with GrassPlot data are welcome to submit proposals to the Governing Board

Cortical Activity during Postural Audio-Biofeedback: A Study Based on Quantitative EEG

The control of postural sway depends on the dynamic integration of multisensory information in the Central Nervous System. Augmentation of sensory information, such as during auditory biofeedback (ABF) of the trunk acceleration, has been shown to improve postural control. We evaluated, by means of quantitative electroencephalography (EEG), which are the basic processes in the brain involved in the perception and cognition of auditory signals used for ABF. ABF and Fake ABF (FAKE) auditory stimulations were delivered to 10 healthy naive subjects during quiet standing postural tasks, with eyes open and closed. Trunk acceleration and 19-channels EEG were recorded at the same time. Advanced, state-of-the-art EEG analysis and source modeling methods were employed to assess the possibly differential, functional activation and localization of EEG spectral features (power in the α, β, and γ bands) between the FAKE and the ABF conditions, for both the eyes open and the eyes closed tasks. Subjects gained advantage by ABF in reducing their postural sway, as measured by a reduction of the root mean square of trunk acceleration during the ABF compared to the FAKE condition. EEG outcomes support the idea that ABF for postural control heavily modulates (increases) the cortical activation in healthy subjects. Population-wise cortical localization analysis (based on the sLORETA method) performed on the comparison FAKE - ABF revealed: i) a significant decrease (p < 0.05) of α power in the right inferior parietal cortex (Brodmann area 40) for the eyes open task; ii) a significant increase (p < 0.05) of γ power in the left temporo-occipital areas in the eyes open task (Brodmann areas 17,18,19, and 30); iii) a significant increase (p < 0.05) of γ power in left temporo-parietal areas for the eyes closed task (Brodmann areas 21,37, and 41). All in all, the findings reported above suggest a completely different usage of the ABF sound by healthy subjects in the EC Task as compared to the EO Task. It would indeed seem that, in the eyes open task, the spatial information coded in the ABF sound is primarily used by the brain in association with visual information: the significant decrease of α power in the right IPL and the significant increase of γ power in primary and associative visual areas suggest that the ABF sound could i) just modulate the processing of visual information and ii) trigger some specific multi-sensory integration processes in areas associated with multisensory, perceptual integration. It is obvious that, in the eyes closed task, the brain cannot use the visual information. In the absence of visual information, the perception and the elaboration of the spatial content of the ABF sound would originate, at least partially, by an additional processing workload of the associative cortical auditory areas in the left temporal lobe and in the left temporo-parietal junction. This hypothesis is consistent with the fact that a significant increase of γ power due to ABF was found for the eyes closed task, but not for the eyes open task