73 research outputs found

    Processus d’évaluation des compĂ©tences en formation Ă  distance dans une approche collaborative en enseignement supĂ©rieur

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    Comprend des rĂ©fĂ©rences bibliographiquesCette recherche prĂ©sente des rĂ©sultats d’une recherche-action-formation visant Ă  amĂ©liorer un processus d’évaluation des compĂ©tences en formation Ă  distance dans une approche collaborative en enseignement supĂ©rieur. Recueillis principalement au moyen d’analyse de documentations produites, d’entrevues semi-structurĂ©es et d’artefacts conçus lors d’une formation auprĂšs de concepteurs, de producteurs et de tuteurs engagĂ©s dans une genĂšse instrumentale, les rĂ©sultats exposent un modĂšle de processus d’évaluation des compĂ©tences en formation Ă  distance qui Ă©mergent de plusieurs processus impliquant la collaboration entre les groupes d’acteurs

    Identifying the origin of geomaterials of original and restored parts of a 14th century alabaster annunciation group through stable isotopes

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    International audienceThe origin of raw materials for sculpture is often obscure before the 17th century due to the scarcity of written sources. Identifying this origin provides hints to economic exchanges but also, potentially, allows for attributing sculptures to a specific context of creation (regional workshops, artists). Another challenge for art historians is the identification of restorations and their potential chronology. We present an example of a 14th century group of two statues, made of gypsum alabaster, representing an annunciation group, with the Virgin Mary and the angel Gabriel. Their original position was a near Troyes in the eastern Paris Basin, they are now separated being conserved at the Louvre Museum (Virgin Mary) and the Cleveland Museum of Art (Gabriel). Our multi-isotope study revealed the common origin of the material used for both sculptures, their isotope fingerprints being identical within the analytical error. These fingerprints are highly specific and point to an origin in a historical gypsum and alabaster quarry in the northern part of Provence, France, first mentioned at the end of the 13th century. We were also able to identify an unknown restoration of lower part of the Virgin Mary statue with an optically undistinguishable material, using Tuscan alabaster, most likely in the 19th century. Two other 14th century statues of the Virgin Mary originally situated in eastern and southeastern France can also be linked to this quarry. This underlines the potential and usefulness of independent geochemical evidence to underpin stylistic hypotheses on grouping of individual artworks, historical economic relationships between regions and on past restoration activities

    Water-repellent and biocide treatments: Assessment of the potential combinations

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    International audienceIt is a common practice to use several chemical products during restoration projects of monuments or sculptures. However, care must be taken when combining the products to avoid a misuse. For example, it is well-known that applying a biocide on stone before a water-repellent leads to a diminishment of the hydrophobic effect of the treatment. But the application of biocide after a water-repellent treatment has been poorly analysed, although studies have proven that the stone looses its hydrophobicity after the application of the biocide. Henceforth, this study investigates the effects of biocide application on a water-repellent film and focuses on the possibilities to restore the efficiency of the previous water-repellent treatment (after the application of the biocide). At first, the tests were performed on glass slides to understand the mechanisms, with the subsequent results revealing that the biocide product deposits on the water-repellent film. Then, the study focuses on determining methods to remove the remains of biocide on limestone samples, previously treated with a water-repellent. The water-repellent used in the study is an alkylpolysiloxane, Rhodorsil H224 from Rhodia

    Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

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    A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P=9.2 × 10-20), ER-negative BC (P=1.1 × 10-13), BRCA1-associated BC (P=7.7 × 10-16) and triple negative BC (P-diff=2 × 10-5). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P=2 × 10-3) and ABHD8 (P<2 × 10-3). Chromosome conformation capture identifies interactions between four candidate SNPs and ABHD8, and luciferase assays indicate six risk alleles increased transactivation of the ADHD8 promoter. Targeted deletion of a region containing risk SNP rs56069439 in a putative enhancer induces ANKLE1 downregulation; and mRNA stability assays indicate functional effects for an ANKLE1 3â€Č-UTR SNP. Altogether, these data suggest that multiple SNPs at 19p13 regulate ABHD8 and perhaps ANKLE1 expression, and indicate common mechanisms underlying breast and ovarian cancer risk

    Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

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    A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P = 9.2 x 10(-20)), ER-negative BC (P = 1.1 x 10(-13)), BRCA1-associated BC (P = 7.7 x 10(-16)) and triple negative BC (P-diff = 2 x 10(-5)). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P = 2 x 10(-3)) and ABHD8 (PPeer reviewe

    Pourquoi et comment mobiliser l'activité fantasmatique de l'élÚve? Pour une lecture subjective du Roi des Trois Orients.

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        Naissance du sujet de mĂ©moire     D’aprĂšs Wolfgang Iser, « L’auteur et le lecteur prennent donc une part Ă©gale au jeu de l’imagination (
). La lecture ne devient un plaisir que si la crĂ©ativitĂ© entre en jeu, que si le texte nous offre une chance de mettre nos aptitudes Ă  l’épreuve. ». Pour tenter de rĂ©flĂ©chir Ă  une problĂ©matique, je suis partie d’une question trĂšs gĂ©nĂ©rale que je me posais : comment dĂ©velopper le plaisir de lire chez les Ă©lĂšves en se plaçant dans une pĂ©dagogie constructi..

    "Des pays entiers densément peuplés faits de lettres" (Benjamin) dans l'Alphabet de Sonia Delaunay et Jacques Damase

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    Les abécédaires permettent aux enfants d'apprendre les lettres et constituent parfois un premier pas vers l'apprentissage de la lecture de maniÚre artistique comme c'est le cas de Alphabet dans lequel l'artiste Sonia Delaunay illustre les comptines de Jacques Damase. Chaque double page de l'abécédaire est consacré à une lettre de l'alphabet. Le rapport à l'espace de la page ainsi que la présence de multiples couleurs nous permettent de mettre en relation la double page du T de l'abécédaire av..

    "Des pays entiers densément peuplés faits de lettres" (Benjamin) dans l'Alphabet de Sonia Delaunay et Jacques Damase

    No full text
    Les abécédaires permettent aux enfants d'apprendre les lettres et constituent parfois un premier pas vers l'apprentissage de la lecture de maniÚre artistique comme c'est le cas de Alphabet dans lequel l'artiste Sonia Delaunay illustre les comptines de Jacques Damase. Chaque double page de l'abécédaire est consacré à une lettre de l'alphabet. Le rapport à l'espace de la page ainsi que la présence de multiples couleurs nous permettent de mettre en relation la double page du T de l'abécédaire av..

    Pourquoi et comment mobiliser l'activité fantasmatique de l'élÚve? Pour une lecture subjective du Roi des Trois Orients.

    No full text
        Naissance du sujet de mĂ©moire     D’aprĂšs Wolfgang Iser, « L’auteur et le lecteur prennent donc une part Ă©gale au jeu de l’imagination (
). La lecture ne devient un plaisir que si la crĂ©ativitĂ© entre en jeu, que si le texte nous offre une chance de mettre nos aptitudes Ă  l’épreuve. ». Pour tenter de rĂ©flĂ©chir Ă  une problĂ©matique, je suis partie d’une question trĂšs gĂ©nĂ©rale que je me posais : comment dĂ©velopper le plaisir de lire chez les Ă©lĂšves en se plaçant dans une pĂ©dagogie constructi..
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