Measurement of CP observables in B± → D(⁎)K± and B± → D(⁎)π± decays

Measurements of CP observables in B ± →D (⁎) K ± and B ± →D (⁎) π ± decays are presented, where D (⁎) indicates a neutral D or D ⁎ meson that is an admixture of D (⁎)0 and D¯ (⁎)0 states. Decays of the D ⁎ meson to the Dπ 0 and Dγ final states are partially reconstructed without inclusion of the neutral pion or photon, resulting in distinctive shapes in the B candidate invariant mass distribution. Decays of the D meson are fully reconstructed in the K ± π ∓ , K + K − and π + π − final states. The analysis uses a sample of charged B mesons produced in pp collisions collected by the LHCb experiment, corresponding to an integrated luminosity of 2.0, 1.0 and 2.0 fb −1 taken at centre-of-mass energies of s=7, 8 and 13 TeV, respectively. The study of B ± →D ⁎ K ± and B ± →D ⁎ π ± decays using a partial reconstruction method is the first of its kind, while the measurement of B ± →DK ± and B ± →Dπ ± decays is an update of previous LHCb measurements. The B ± →DK ± results are the most precise to date

The LHCb upgrade I

The LHCb upgrade represents a major change of the experiment. The detectors have been almost completely renewed to allow running at an instantaneous luminosity five times larger than that of the previous running periods. Readout of all detectors into an all-software trigger is central to the new design, facilitating the reconstruction of events at the maximum LHC interaction rate, and their selection in real time. The experiment's tracking system has been completely upgraded with a new pixel vertex detector, a silicon tracker upstream of the dipole magnet and three scintillating fibre tracking stations downstream of the magnet. The whole photon detection system of the RICH detectors has been renewed and the readout electronics of the calorimeter and muon systems have been fully overhauled. The first stage of the all-software trigger is implemented on a GPU farm. The output of the trigger provides a combination of totally reconstructed physics objects, such as tracks and vertices, ready for final analysis, and of entire events which need further offline reprocessing. This scheme required a complete revision of the computing model and rewriting of the experiment's software

Measurement of CPCP asymmetries in D±→η′π±D^{\pm}\rightarrow \eta^{\prime} \pi^{\pm} and Ds±→η′π±D_s^{\pm}\rightarrow \eta^{\prime} \pi^{\pm} decays

See paper for full list of authors - All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-041.html - Submitted to Phys. Lett. BInternational audienceA search for CP violation in D±→η′π± and D±s→η′π± decays is performed using proton-proton collision data, corresponding to an integrated luminosity of 3 fb−1, recorded by the LHCb experiment at centre-of-mass energies of 7 and 8 TeV. The measured CP-violating charge asymmetries are ACP(D±→η′π±)=(−0.61±0.72±0.55±0.12)% and ACP(D±s→η′π±)=(−0.82±0.36±0.24±0.27)%, where the first uncertainties are statistical, the second systematic, and the third are the uncertainties on the ACP(D±→K0Sπ±) and ACP(D±s→ϕπ±) measurements used for calibration. The results represent the most precise measurements of these asymmetries to date

Measurement of B0B^0, Bs0B^0_s, B+B^+ and Λb0\Lambda^0_b production asymmetries in 7 and 8 TeV proton-proton collisions

See paper for full list of authors - All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-062.html - Submitted to Phys. Lett. B.International audienceThe B0, B0s, B+ and Λ0b hadron production asymmetries are measured using a data sample corresponding to an integrated luminosity of 3.0 fb−1, collected by the LHCb experiment in proton-proton collisions at centre-of-mass energies of 7 and 8 TeV. The measurements are performed as a function of transverse momentum and rapidity of the b hadrons within the LHCb detector acceptance. The overall production asymmetries, integrated over transverse momentum and rapidity, are also determined

First observation of forward Z→bbˉZ \rightarrow b \bar{b} production in pppp collisions at s=8\sqrt{s}=8 TeV

The decay Z→bb¯ is reconstructed in pp collision data, corresponding to 2 fb −1 of integrated luminosity, collected by the LHCb experiment at a centre-of-mass energy of s=8 TeV. The product of the Z production cross-section and the Z→bb¯ branching fraction is measured for candidates in the fiducial region defined by two particle-level b -quark jets with pseudorapidities in the range 2.220 GeV and dijet invariant mass in the range 4520$GeV and dijet invariant mass in the range$45 < m_{jj} < 165$GeV. From a signal yield of$5462 \pm 763$$Z \rightarrow b \bar{b}$events, where the uncertainty is statistical, a production cross-section times branching fraction of$332 \pm 46 \pm 59$pb is obtained, where the first uncertainty is statistical and the second systematic. The measured significance of the signal yield is 6.0 standard deviations. This measurement represents the first observation of the$Z \rightarrow b \bar{b}$production in the forward region of$pp$ collisions

Growth And Body Composition In Children With Type 1 Diabetes Mellitus [crescimento E Composição Corporal De Crianças Com Diabetes Mellitus Tipo 1]

Objective: To evaluate the growth and body composition of pre-pubertal diabetic children, and to check for influence of the age of diabetes onset and length, sex, insulin requirement and glycosylated hemoglobin. Patients and methods: 59 diabetic children (39 M; 29 F), age 1.2-11.5 years, and 67 controls (36 M; 31 F), age 1.2-11.7 years were included. Weight, height, body mass index (BMI), arm circumference, skin folds, fat mass and muscle areas were evaluated and transformed into standard deviation scores (SDS). Results: Among the diabetic children the mean height SDS was -0.13 (± 0.97) while in the control group it was 0.28 (± 0.86) (p= 0.013). The difference between the first and the current height SDS showed that the height SDS decreased significantly (p< 0.001) and multiple regression analysis indicated correlation with the duration of the disease. The mean arm fat SDS also revealed difference (p< 0.001). The means for weight, BMI, addition of 3 skinfolds and muscle mass did not demonstrate difference between the groups. Conclusions: The diabetic children showed reduction of height SDS during the period studied and they were significantly shorter than the controls, even though their statures were within the population standards. The arm fat area also showed to be increased in relation with the controls.503490498Manna, T.D., Damiani, D., Dichtchekenian, V., Setian, N., Diabetes Mellitus na Infância e na Adolescência (2004) Endocinologia Pediátrica, 2a Ed., pp. 195-241. , Setian N, editora. São Paulo: SarvierSilva Jr., G.R., Fuks, A.G., Cunha, E.F., Clemente, E.L.S., Gomes, M.B., Inter-relação de variáveis demográficas, terapêutica insulínica e controle glicêmico em pacientes com diabetes mellitus do tipo 1 atendidos em um hospital universitário (1999) Arq Bras Endocrinol Metab, 43, pp. 114-120Ferreira, S.R.G., Franco, L.J., Vivolo, M.A., Negrato, C.A., Simões, A.C.P., Ventureli, C.R., Population based incidence of IDDM in the state of São Paulo, Brazil (1993) Diabetes Care, 16, pp. 701-704Maia, F.F.R., Araújo, L.R., Síndrome de Mauriac: Forma rara do diabetes mellitus tipo 1 (2002) Arq Bras Endocrinol Metab, 46, pp. 310-315Herber, S.M., Dunsmore, I.R., Does control affect growth in diabetes mellitus? (1988) Acta Paediatr Scand, 77, pp. 303-305Cunha, E.F., Silva Jr., G.R., Clemente, E.L.S., Gomes, M.B., Crescimento de crianças diabéticas em controle ambulatorial em hospital universitário (1999) Arq Bras Endocrinol Metab, 43, pp. 344-350Dunger, D.B., Edge, J.E., Ahmed, M.L., Diabetes mellitus and growth (1995) Curr Opin Endocrinol Diab, 2, pp. 97-104Rodrigues, T.M.B., Silva, I.N., Estatura final de pacientes com Diabetes Mellitus tipo 1 (2001) Arq Bras Endocrinol Metab, 45, pp. 108-114Dunger, D., Ahmed, L., Ong, K., Growth and body composition in type 1 Diabetes Mellitus (2002) Horm Res, 58, pp. 66-71Clinical Pratice Recomendation 2003 (2003) Diabetes Care, 26, pp. S5-20(2004) A Importância Da HbGli (A1c) para a Avaliação Do Controle Glicêmico Em Pacientes Com Diabetes Mellitus: Aspectos Clínicos e Laboratoriais, , Posicionamento Oficial das Sociedades Brasileiras de Endocrinologia e Metabologia, de Patologia Clínica, de Diabetes, da Associaçã o Latino-Americana de Diabetes e da Federação Nacional das Associações e Entidades de Diabetes, São PauloLohman, T.G., Roche, A.F., Martorell, R., (1988) Anthropometric Standardization Reference Manual, , Illinois: Human Kinetics BooksFrisancho, A.R., (1993) Anthropometric Standards for the Assessment of Growth and Nutritional Status, , Michigan: University of Michigan PressKuczmarski, R.J., Ogden, C.L., Grummer-Strawn, L.M., Flegal, K.M., Mei, Z., Guo, S., CDC growth charts: United States (2000) Adv Data, 8, pp. 1-27Ogden, C.L., Kuczmarski, R.J., Flegal, K.M., Mei, Z., Guo, S., Wei, R., Centers for Disease Control and Prevention 2000 growth charts for the United States: Improvements to the 1977 National Center for Health Statistics version (2002) Pediatrics, 109, pp. 45-60Goran, M.I., Kaskoun, M.C., Carpenter, W.H., Poehlman, E.T., Ravussin, E., Fontvieille, A.M., Estimating body composition of young children by using bioeletrical resistance (1993) J Appl Physiol, 75, pp. 1776-1780Fomon, S., Hanschke, F., Ziegler, E., Nelson, B., Body composition of reference children from birth to age 10 years (1982) Am J Nutr, 35, pp. 1169-1175Danne, T., Kordonouri, O., Enders, I., Weber, B., Factors influencing height and weight development in children with diabetes - Results of the Berlin retinopathy study (1997) Diabetes Care, 20, pp. 281-285Petersen, H.D., Korsgaard, B., Deckert, T., Nielsen, E., Growth, body weight and insulin requirement in diabetic children (1978) Acta Paediatr Scand, 67, pp. 453-457Thon, A., Heinze, E., Feilen, K.D., Holl, R.W., Schmidt, H., Koletzko, S., Development of height and weight in children with diabetes mellitus: Report on two prospective multicentre studies, one cross-sectional, one longitudinal (1992) Eur J Pediatr, 151, pp. 258-262Malone, J.I., Growth and sexual maturation in children with insulin-dependent diabetes mellitus (1993) Curr Opin Pediatr, 5, pp. 494-498Ozuna, B., Aruza, A., Belgorosky, A., Mazza, C., Estudio del crecimiento en niños com diabetes insulino dependente. Efectos del control metabólico (1995) Med Infant, 2, p. 147Sepúlveda, Z.N., Jaime Perez, C., Iris Mella, G., Crecimiento en niños con diabetes mellitus insulino-dependente (1997) Rev Chil Pediatr, 68, pp. 61-65The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus (1993) N Engl J Med, 329, pp. 977-986Pitukcheewanont, P., Alemzadeh, R., Jacobs, W.R., Jones, B.H., Eberle, A.J., Does glycemic control affect growth velocity in children with insulin-dependent diabetes mellitus (1995) Acta Diabetol, 32, pp. 148-152Salerno, M.C., Argenziano, A., Di Maio, S., Gasparini, N., Formicola, S., De Fellipo, G., Puberal growth, sexual maturation, and final height in children with IDDM (1997) Diabetes Care, 20, pp. 721-723Bognetti, E., Riva, M.C., Bonfanti, R., Meschi, F., Viscardi, M., Chiumello, G., Growth changes in children and adolescents with short-term diabetes (1998) Diabetes Care, 21, pp. 1226-1229Lebl, J., Schober, E., Zidek, T., Baldis, S., Rami, B., Pruhova, S., Growth data in large series of 587 children and adolescents with type 1 diabetes mellitus (2003) Endocr Regul, 37, pp. 153-161Meira, S.O., Morcillo, A.M., Lemos-Marini, S.H.V., Paulino, M.F.V.M., Minicucci, W.J., Guerra Jr., G., Crescimento puberal e altura final em 40 pacientes com diabetes mellitus tipo 1 (2005) Arq Bras Endocrinol Metab, 49, pp. 396-402Brown, M., Ahmed, M.L., Clayton, K.L., Dunger, D.B., Growth during childhood and final height in type 1 diabetes (1994) Diabetic Medicine, 11, pp. 182-187Zachrisson, I., Brismar, K., Hall, K., Wallensteen, M., Dahlqvist, G., Determinants of growth in diabetic pubertal subjects (1997) Diabetes Care, 20, pp. 1261-1265Scheffer-Marinus, P.D., Links, T.P., Reitsma, W.D., Drayer, N.M., Increased height in diabetes mellitus corresponds to the predicted and the adult height (1999) Acta Paediatr, 88, pp. 384-388Castro, J.C., Goulart, E.M.A., Camargos, A.F., Chagas, A.J., Avaliação antropométrica e bioquímica de crianças e adolescentes com diabetes do tipo 1 comparados a um grupo de não diabéticos de mesmo nível sócioeconômico (2000) Arq Bras Endocrinol Metab, 44, pp. 502-508Tattersall, R.B., Pyke, D.A., Growth in diabetic children: Studies in identical twins (1973) Lancet, 17, pp. 1105-1109Pietilläinen, K.H., Virtanen, S.M., Rissanen, A., Rita, H., Mäenpää, A., Diet, obesity, and metabolic control in girls with insulin dependent diabetes mellitus (1995) Arch Dis Child, 73, pp. 398-402Du Caju, M.V.L., Rooman, R.P., Beeck, L.O., Longitudinal data on growth and final height in diabetic children (1995) Pediatr Res, 38, pp. 607-611Ferrante, E., Pitzalis, G., Vania, A., Angelis, P., Guidi, R., Fontana, L., Stato nutrizionale, obesità ed equilibrio metabolico in soggetti in età evolutiva affeti da diabete mellito di tipo 1 (1999) Minerva Pediatr, 51, pp. 39-46Ingberg, C.M., Sarnblad, S., Palmer, M., Schvarez, E., Berne, C., Amont, T., Body composition in adolescent girls with type 1 diabetes. Diabetes UK (2003) Diabet Med, 20, pp. 1005-1011Villalpando, S., Hermida, I., Esquivel, S., Ramos, L., Barrón, C., Pérez-Pasten, E., Growth and body composition measured by anthropometry in healthy and diabetic children (1984) Rev Invest Clin (Mex), 36, pp. 321-32

Growth In Patients With The Salt-wasting Form Of Congenital Adrenal Hyperplasia During The First Two Years Of Life [crescimento De Pacientes Com Hyperplasia Congênita Das Supra-renais, Forma Perdedora De Sal, Nos Dois Primeiros Anos De Vida]

Objectives: to assess the growth and nutritional recovery of patients with the classical salt-wasting form of congenital adrenal hyperplasia in the first two years of life. Methods: z scores for weight and height were calculated for 21 patients at birth, on the occasion of the first medical consultation and at one and two years of age. The concentrations of 17-hydroxyprog-esterone, androstenedione and the doses of hydrocortisone prescribed at the first medical concentrations up to the age of two years were determined (at one and two years of age respectively). Results: the mean age for the first medical consultation was 36.7 days. The z score for weight at birth was -0.23±1.4; on the occasion of the first consultation -2.31±1.3; at the age of one year -1.43±1.6 and at the age of two years -0.77± 1.3. The z score for height at birth was -0.69±2.3; on the occasion of the first consultation -1.87±1.7; at one year of age - 1.68±1.1 and at two years -1.07±1.0. The difference between the scores at two years of age and on the occasion of the first medical consultation was 1.54±1.7 for weight and 0.80±1.6 for height. The mean dosage of hydrocortisone prescribed was 21.3 and 19.9 mg/m2/day for periods 1 and 2 and the concentrations (ng/dL) of 17-hydroxyprogesterone and androstenedione were 9.1 and 0.14 for period 1 and 4.4 and 0.27 for period 2. Conclusions: nutritional recovery was observed to occur on treatment and, at two years of age, weight and height are normal, although below the average for the population at large.94415421Technical report: Congenital adrenal hyperplasia (2000) Pediatrics, 106, pp. 1511-1518. , American Academy of PediatricsNguyen, A.T., Brown, J.J., Warne, G.L., Growth in congenital adrenal hyperplasia (2006) Indian J Pediatr, 73, pp. 89-93New, M.I., An update of congenital adrenal hyperplasia (2004) Ann N Y Acad Sci, 1038, pp. 14-43Pang, S., Congenital adrenal hyperplasia (1997) Endocrinol Metab Clin North Am, 26, pp. 853-891Forest, M.G., Recent advances in the diagnosis and management of congenital adrenal hyperplasia due to 21-hydroxylase deficiency (2004) Hum Reprod Update, 10, pp. 469-485Miller, W.L., Genetics, diagnosis, and management of 21-hydroxilase deficiency (1994) J Clin Endocrinol Metab, 78, pp. 241-246Girgis, R., Winter, J.S.D., The effects of glucocorticoid replacement therapy on growth, bone mineral density, and bone turnover markers in children with congenital adrenal hyper-plasia (1997) J Clin Endocrinol Metab, 82 (3), pp. 926-929Eugster, E.A., Dimeglio, L.A., Wright, J.C., Freidenberg, G.R., Seshadri, R., Pescovitz, O.H., Height outcome in congenital adrenal hyperplasia caused by 21 hydroxylase deficiency: A meta-analysis (2001) J Pediatr, 138, pp. 26-32Cameron, F.J., Kaymakci, B., Byrt, E.A., Ebeling, P.R., Warne, G.L., WalkJD. Bone mineral density and body composition in congenital adrenal hyperplasia (1995) J Clin Endocrinol Metab, 80, pp. 2238-2243Cornean, R.E., Hindmarsh, P.C., Brook, C.G., Obesity in 21-hydroxylase deficient patients (1998) Arch Dis Child, 78, pp. 261-263Migeon, C.J., Donohoue, P.A., Congenital adrenal hyperplasia caused by 21-hydroxylase deficiency. Its molecular basis and its remaining therapeutic problems (1991) Endocrinol Metab Clin North Am, 20, pp. 277-296Merke, D.P., Bornstein, S.R., Congenital adrenal hyperplasia (2005) Lancet, 365, pp. 2125-2136Schwartz, R.P., Back to basics: Early diagnosis and compliance improve final height outcome in congenital adrenal hyperplasia (2001) J Pediatr, 138, pp. 3-5Manoli, I., Kanaka-Gantenbein, C.H., Voutetakis, A., Maniati-Christidi, M., Dacou-Voutetakis, A., Early growth, pubertal development, body mass index and final height of patients with congenital adrenal hyperplasia: Factors influencing the outcome (2002) Clin Endocrinol (oxf), 57, pp. 669-676Savage, M.O., Scommegna, S., Carroll, P.V., Ho, J.T., Monson, J.P., Besser, G.M., Grossman, A.B., Growth in disorders of adrenal hyperfunction (2002) Horm Res, 58 (SUPPL. 1), pp. 39-43van der Kamp, H.J., Otten, B.J., Buitenweg, N., de Munick Keiser-Schrama, S.M.P.F., Oostdijk, W., Jansen, M., Delemarre-de-Waal, H.A., Wit, J.M., Longitudinal analysis of growth and puberty in 21-hydroxylase deficiency patients (2002) Arch Dis Child, 87, pp. 139-144Lemos-Marini, S.H.V., Guerra-Júnior, G., Morcillo, A.M., Baptista, M.T.M., Silva, L.O., Maciel-Guerra, A.T., Hiperplasia congênita das supra-renais por deficiência da 21-hidroxilase: Altura final de 27 pacientes com a forma clássica (2005) Arq Bras Endocrinol Metab, 49, pp. 902-907Hargitai, G., Sólyom, J., Battelino, T., Lebl, J., Pribilincová, Z., Hauspie, R., Kovács, J., Frisch, H., Growth patterns and final height in congenital adrenal hyperplasia due to classical 21-hydroxylase deficiency. Results of a multicenter study (2001) Horm Res, 55, pp. 161-171. , and the MEWPE-CAH study group(2000) Cdc Growth Charts: United States, , http://www.cdc.gov/growthcharts/, National Center for Health Statistics, [cited on 2007 mar 8] Available fromRamos, C.C.A., Bento, L.R., Gonçalves, E.M., De-Mello, M.P., Baptista, M.T.M., Lemos-Marini, S.H.V., Guerra-Junior, G., Avaliação do crescimento, do controle laboratorial e da corticoterapia em um grupo de pacientes com a forma clássica da deficiência da 21-hidroxilase (2007) Rev Paul Pediatr, 25, pp. 317-323Gussinye, M., Potau, N., Vicens-Calvet, E., Albisu, M.A., Yeste, D., Ibanez, L., Audí, L., Carrascosa, A., Adult height, pattern of growth and pubertal development in patients with congenital adrenal hyperplasia, salt losing form (1997) Med Clin (barc), 108, pp. 87-9